Methadone Hcl combined with Mirtazapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 3/23/2006 United States
Primary
Concomitant
Paralysis Hospitalization 3/1/2006 53 Male 4/6/2006 Physician Spain
Primary
Concomitant
Anaphylactoid Reaction Life Threatening 11/15/2005 34 Male 4/7/2006 Other Health Professional Australia
Primary
Secondary
Suicide Attempt 21 Male 4/13/2006 Other Health Professional Australia
Primary
Secondary
Suicide Attempt 21 Male 5/4/2006 Australia
Primary
Secondary
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 5/12/2006 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 12/17/2005 41 Male 5/15/2006 Switzerland
Primary
Secondary
Concomitant
Completed Suicide Death 32 5/23/2006 Physician United States
Primary
Secondary
Completed Suicide Death 52 5/23/2006 Physician United States
Primary
Secondary
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/14/2006 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 6/23/2006 Female 130 lb 6/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/26/2006 14 Male 6/30/2006 Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 45 Male 7/3/2006 Other Health Professional Switzerland
Primary
Concomitant
Somnolence Other Serious 6/26/2006 14 Male 7/14/2006 Other Health Professional Germany
Primary
Secondary
Suicide Attempt Other Serious 6/26/2006 14 Male 7/14/2006 Other Health Professional Germany
Primary
Secondary
Pain 5/1/2006 46 Female 8/22/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 9/6/2006 United States
Primary
Concomitant
Syncope Hospitalization 45 Male 9/5/2006 Switzerland
Primary
Concomitant
Thrombocytopenia Life Threatening 11/7/2005 41 Female 11/15/2006 Physician Germany
Primary
Concomitant
Transaminases Increased 9/29/2006 Male 11/24/2006 Germany
Primary
Concomitant
Drug Toxicity Death 29 Male 12/29/2006 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 38 Male 1/11/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 12/16/2004 Female 119 lb 3/2/2007 Lawyer United States
Primary
Concomitant
Sudden Death Death 3/3/2007 20 Male 4/19/2007 Switzerland
Primary
Secondary
Concomitant
Obsessive-compulsive Disorder Other Serious 27 Male 6/14/2007 Physician Switzerland
Primary
Secondary
Concomitant
Drug Tolerance Hospitalization 18 Male 8/27/2007
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Pain Other Serious 9/1/2007 30 Female 11/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 49 Male 1/15/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 49 Male 1/28/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 49 Male 2/13/2008 Physician United States
Primary
Secondary
Suicidal Ideation Death 3/3/2007 20 Male 4/3/2008 Switzerland
Primary
Secondary
Concomitant
Drug Toxicity Death 38 Male 4/16/2008 Sweden
Primary
Concomitant
Respiratory Arrest Death 49 Male 5/9/2008 United States
Primary
Secondary
Underweight 5/13/2008 Female 5/22/2008 Other Health Professional Ireland
Primary
Secondary
Withdrawal Syndrome Other Serious 3/1/1999 23 Female 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Talipes Congenital Anomaly 5/11/2008 Female 6/3/2008 Ireland
Primary
Secondary
Weight Increased Disability 9/11/2007 Female 103 lb 6/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Weight Increased Disability 9/11/2007 Female 103 lb 6/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Weight Increased Disability 9/11/2007 Female 103 lb 6/10/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Disability 9/11/2007 Female 103 lb 6/13/2008 Physician United Kingdom
Primary
Concomitant
Post Procedural Complication Other Serious 5/1/2008 Female 8/28/2008 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 7/4/2008 Female 8/28/2008 United Kingdom
Primary
Concomitant
Oropharyngeal Pain Other Serious 7/4/2008 31 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Septal Defect Life Threatening 1/1/2006 Female 9/24/2008 France
Primary
Secondary
Vomiting Hospitalization 7/16/2008 44 Male 10/15/2008 Spain
Primary
Concomitant
Right Ventricular Hypertrophy 32 Male 10/29/2008 United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 9/23/2008 Male 11/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/16/2008 44 Male 11/11/2008 Spain
Primary
Concomitant
Right Ventricular Hypertrophy Other Serious 32 Male 11/13/2008
Primary
Concomitant
Right Ventricular Hypertrophy Other Serious 32 Male 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Hypertrophy Other Serious 32 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Male 11/24/2008 United Kingdom
Primary
Secondary
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Tremor 11/8/2008 74 Male 12/5/2008 Switzerland
Primary
Concomitant
Urinary Retention Other Serious 9/23/2008 Male 12/15/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Hypertrophy Other Serious 32 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Projectile Male 12/26/2008 United Kingdom
Primary
Secondary
Vomiting Projectile Male 1/8/2009 United Kingdom
Primary
Secondary
Vomiting 12/22/2008 38 Male 1/23/2009 United Kingdom
Primary
Secondary
Vomiting Projectile Other Serious Male 1/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 12/22/2008 38 Male 2/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Projectile Other Serious Male 2/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Projectile Other Serious Male 2/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Projectile 12/22/2008 38 Male 2/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 1/1/2008 Male 2/18/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Arrest Death 49 Male 2/25/2009 Physician United States
Primary
Secondary
Hepatic Encephalopathy Life Threatening 4/18/2009 50 Male 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 4/18/2009 50 Male 6/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 4/18/2009 50 Male 7/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Level Increased Life Threatening 4/18/2009 50 Male 6/30/2009 United Kingdom
Primary
Concomitant
Tremor Other Serious Female 8/11/2009 United States
Primary
Secondary
Weight Increased Other Serious 9/11/2007 41 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/11/2007 41 Female 11/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/11/2007 41 Female 11/5/2009 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 9/11/2007 41 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 55 Female 108 lb 1/26/2010 Other Health Professional United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death Male 185 lb 3/18/2010 Consumer United States
Primary
Secondary
Concomitant
Clonus Hospitalization 11/22/2009 58 Female 4/6/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/22/2008 38 Male 176 lb 4/8/2010 United Kingdom
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 1/1/2008 58 Female 190 lb 7/26/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Fall Hospitalization 4/1/2008 58 Female 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Death Death 33 Male 1/25/2011 Other Health Professional Australia
Primary
Secondary
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Death 38 Male 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 28 Male 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 8/10/2009 43 Male 6/3/2011 Physician Canada
Primary
Secondary
Concomitant
Influenza Like Illness Death 38 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 28 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 28 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 28 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 28 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Depression Other Serious 44 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxoplasma Serology Positive Hospitalization 5/7/2005 58 Male 174 lb 6/29/2011 United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 38 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 38 Male 7/5/2011 Physician United Kingdom
Primary
Secondary
Angina Unstable Hospitalization Male 246 lb 7/7/2011 Physician United States
Primary
Secondary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 44 7/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 7/4/2011 Physician United Kingdom
Primary
Concomitant
Influenza Like Illness Other Serious 38 Male 7/4/2011 Physician United Kingdom
Primary
Concomitant
Accidental Poisoning Death 46 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Death 44 7/12/2011 Other Health Professional Australia
Primary
Secondary
Toxicity To Various Agents Death 44 7/12/2011 Other Health Professional Australia
Primary
Secondary
Respiratory Depression Death 44 7/12/2011 Other Health Professional Australia
Primary
Secondary
Influenza Like Illness Death 38 Male 7/12/2011 Physician United Kingdom
Primary
Concomitant
Influenza Like Illness Death 38 Male 7/12/2011 Physician United Kingdom
Primary
Concomitant
Toxicity To Various Agents Death 28 Male 7/1/2011 United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 38 Male 7/1/2011 United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxicity To Various Agents Death 28 Male 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Interaction Death 5/7/2011 34 Male 365 lb 7/11/2011 Consumer United States
Primary
Concomitant
Hepatomegaly Death 44 6/30/2011 Physician Australia
Primary
Secondary
Splenomegaly Death 44 7/5/2011 Other Health Professional
Primary
Secondary
Toxicity To Various Agents Other Serious 44 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Death 44 7/4/2011 Australia
Primary
Secondary
Toxicity To Various Agents Other Serious 38 Male 6/28/2011 Saudi Arabia
Primary
Secondary
Toxicity To Various Agents Death 28 Male 7/11/2011 Other Health Professional
Primary
Secondary
Toxicity To Various Agents Death 28 Male 7/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Influenza Like Illness Death 38 Male 7/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Death 44 7/12/2011 Other Health Professional Denmark
Primary
Secondary
Influenza Like Illness Death 38 Male 7/13/2011 Other Health Professional
Primary
Secondary
Concomitant
Snoring Death 44 7/13/2011 Physician Australia
Primary
Secondary
Haemorrhage Death 44 7/20/2011 Physician Australia
Primary
Secondary
Influenza Like Illness Death 38 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 28 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Snoring Death 44 8/4/2011 Other Health Professional Denmark
Primary
Secondary
Arrhythmia Death 44 8/5/2011 Pharmacist Australia
Primary
Secondary
Treatment Noncompliance Hospitalization 8/8/2011 59 Male 236 lb 8/9/2011 United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2003 56 Female 155 lb 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Scar Death 44 8/18/2011 Other Health Professional Australia
Primary
Secondary
Pain Death 8/1/2005 42 Female 257 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Constipation 1/1/2010 56 Female 92 lb 9/22/2011 Consumer United States
Primary
Concomitant
Convulsion Other Serious 8/1/2011 35 Female 9/30/2011 Physician Ireland
Primary
Concomitant
Cardio-respiratory Arrest Death 36 10/20/2011 Other Health Professional United States
Primary
Secondary
Hallucination Hospitalization 4/4/2008 29 Male 10/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyskinesia Other Serious 10/28/2011 22 Male 192 lb 11/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 8/1/2011 35 Female 11/14/2011 Physician Ireland
Primary
Concomitant
Grand Mal Convulsion Other Serious 10/28/2011 22 Male 192 lb 11/16/2011 Other Health Professional
Primary
Secondary
Concomitant
Oculogyric Crisis Other Serious 10/28/2011 22 Male 192 lb 11/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 10/28/2011 22 Male 11/21/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant

Drug Data