Metformin combined with Zyprexa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/12/2005 66 Female 3/3/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/4/2004 42 Male 274 lb 3/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 51 Male 220 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Hyperlipidaemia Hospitalization 1/1/2002 51 Male 220 lb 5/3/2006 Lawyer United States
Primary
Concomitant
Somnolence Hospitalization 10/27/2005 Female 5/19/2006 Physician Canada
Primary
Concomitant
Urine Ketone Body Present Other Serious 9/11/1998 Male 225 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2004 44 Female 244 lb 4/18/2006 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/1999 62 Male 275 lb 6/6/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2003 37 Male 280 lb 6/8/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 7/3/2001 36 Female 300 lb 6/9/2006 Lawyer United States
Primary
Concomitant
Drug Ineffective 2/27/2006 53 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 9/11/1998 Male 225 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2001 36 Female 300 lb 8/13/2006 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 84 Female 180 lb 11/10/2006 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization Female 154 lb 11/16/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2003 56 Female 142 lb 12/4/2006 Consumer United States
Primary
Secondary
Concomitant
Ketoacidosis Other Serious 1/1/2000 49 Male 148 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Erythema Multiforme Other Serious 5/1/2007 62 Female 205 lb 8/13/2007 Physician United States
Primary
Concomitant
Erythema Multiforme Other Serious 5/1/2007 62 Female 205 lb 8/22/2007 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/1/2007 17 Male 166 lb 12/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 194 lb 6/17/2008 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 6/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Congenital Abnormalities Congenital Anomaly 1/25/2005 Female 10 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Torticollis Other Serious 10/17/2007 Female 217 lb 8/22/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 10/15/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 52 Male 1/30/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 37 Male 1/30/2009 Physician United States
Primary
Concomitant
Nausea Hospitalization 1/1/2009 Female 215 lb 2/24/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 3/25/2009 United States
Primary
Concomitant
Tooth Abscess Other Serious 11/19/2001 42 Male 210 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/23/2001 45 Female 314 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 9/21/1999 26 Female 210 lb 4/13/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/28/2009 Male 4/23/2009 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/28/2009 Male 174 lb 5/7/2009 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 5/5/2006 59 Male 257 lb 6/2/2009 United States
Primary
Concomitant
Toxic Encephalopathy Life Threatening 2/1/2009 Male 6/9/2009 Physician United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1995 40 Male 193 lb 6/11/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Weight Increased Other Serious 5/2/2001 40 Female 321 lb 6/29/2009 United States
Primary
Concomitant
Polyneuropathy Other Serious 12/1/2001 50 Female 187 lb 7/1/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/6/2003 53 Female 278 lb 7/29/2009 United States
Primary
Concomitant
Diabetic Complication Other Serious 4/21/2006 47 Female 289 lb 7/29/2009 United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/1/2003 38 Female 160 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 43 Female 233 lb 7/30/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1999 39 Male 258 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2004 51 Male 305 lb 8/5/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 3/4/2004 60 Female 190 lb 8/6/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 46 Female 8/6/2009 United States
Primary
Concomitant
Umbilical Hernia Hospitalization 2/1/2004 52 Female 179 lb 8/6/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/16/2002 47 Male 212 lb 8/6/2009 United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 8/1/2003 45 Male 190 lb 8/7/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2004 40 Female 314 lb 8/10/2009 United States
Primary
Concomitant
Insulin Resistance Other Serious 1/1/2005 31 Female 131 lb 8/12/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 7/6/2005 51 Male 181 lb 8/20/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Faeces Discoloured 9/23/2009 72 Female 172 lb 10/22/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/14/2006 53 Male 247 lb 10/26/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2009 Female 315 lb 11/5/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/3/2009 Female 190 lb 11/5/2009 United States
Primary
Concomitant
Hot Flush 5/1/2009 Male 255 lb 11/25/2009 United States
Primary
Concomitant
Anxiety 62 Female 256 lb 12/9/2009 Consumer United States
Primary
Concomitant
Vomiting 9/1/2009 Female 195 lb 10/27/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 12/16/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Myalgia Disability 1/9/2009 69 Female 225 lb 1/6/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 1/25/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 57 Female 186 lb 1/25/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/15/2010 Male 267 lb 3/26/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 52 Male 200 lb 4/28/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 29 Female 274 lb 6/3/2010 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 1/1/2007 49 Female 160 lb 6/4/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/23/2001 45 Female 314 lb 6/4/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/7/2004 47 Female 147 lb 6/23/2010 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2006 48 Female 198 lb 7/14/2010 United States
Primary
Concomitant
Thinking Abnormal Other Serious Male 7/22/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 55 Female 185 lb 8/25/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2001 58 Male 234 lb 9/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Male 8/27/2010 Physician Norway
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2006 53 Female 163 lb 9/8/2010 United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Female 152 lb 9/15/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 9/4/2010 66 Male 334 lb 9/14/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 51 Male 270 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/18/2003 50 Male 236 lb 9/17/2010 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 10/1/2000 40 Male 279 lb 9/17/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 1/26/2005 32 Female 175 lb 9/17/2010 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 11/1/2002 31 Female 98 lb 9/17/2010 United States
Primary
Concomitant
Hyperglycaemia Other Serious 1/1/2004 41 Female 219 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 48 Female 212 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2003 43 Female 98 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Disability 2/5/2003 40 Male 260 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2002 49 Male 264 lb 9/20/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 39 Male 250 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 59 Female 294 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/1999 49 Male 244 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2005 40 Female 210 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 266 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 32 Male 274 lb 9/20/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2004 42 Female 256 lb 9/20/2010 United States
Primary
Concomitant
Vomiting 5/1/2005 41 Female 180 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 41 Male 315 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/11/2005 54 Female 208 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/20/2005 45 Male 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2005 52 Male 255 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/1999 45 Female 232 lb 9/20/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/24/2005 14 Female 249 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/26/2006 32 Female 227 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 53 Female 223 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 38 Male 204 lb 9/20/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 38 Male 190 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2006 51 Female 342 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 64 Male 144 lb 9/21/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/6/2004 41 Male 181 lb 9/21/2010 United States
Primary
Concomitant
Wound Other Serious 1/31/2003 31 Male 160 lb 9/21/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2004 48 Male 311 lb 9/28/2010 United States
Primary
Concomitant
Hospitalisation Other Serious Female 9/24/2010 Physician United Kingdom
Primary
Concomitant
Schizophrenia, Undifferentiated Type Hospitalization 8/27/2010 18 Male 10/22/2010 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 8/30/2010 66 Male 334 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2010 47 Male 220 lb 11/1/2010 Consumer United States
Primary
Concomitant
Polyuria Other Serious 57 Male 224 lb 11/9/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death 1/13/2004 43 Male 11/18/2010 Other Health Professional United States
Primary
Concomitant
Feeling Abnormal 1/1/2009 39 Female 254 lb 11/24/2010 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 12/1/2008 63 Female 12/2/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Male 159 lb 12/8/2010 Pharmacist Canada
Primary
Concomitant
Tremor Other Serious 1/1/2010 47 Male 220 lb 12/9/2010 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 10 lb 12/10/2010 Lawyer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Male 159 lb 12/14/2010 Pharmacist Canada
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 10 lb 12/13/2010 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 12/8/2010 61 Female 182 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Injection Site Nodule 10/1/2010 45 Female 1/12/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 10/1/2009 56 Female 138 lb 1/28/2011 Consumer United States
Primary
Concomitant
Mood Swings Hospitalization Female 1/31/2011 Consumer United States
Primary
Concomitant
Abnormal Loss Of Weight Other Serious 1/1/2009 53 Male 230 lb 2/7/2011 Consumer United States
Primary
Concomitant
Productive Cough Other Serious 3/27/2009 51 Male 2/15/2011 Other Health Professional Switzerland
Primary
Concomitant
Overdose Other Serious 1/7/2002 38 Female 186 lb 2/25/2011 Consumer Canada
Primary
Secondary
Concomitant

Drug Data