Metformin combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 6/1/2004 Female 4/28/2006 Physician Sweden
Primary
Concomitant
Toothache Other Serious 9/1/2005 61 Male 209 lb 6/5/2006 Consumer Brazil
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 70 Female 271 lb 6/8/2006 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 2/1/2006 88 Male 6/12/2006 United States
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 9/11/2006 59 Male 11/15/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2005 55 Male 11/22/2006 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 9/11/2006 59 Male 11/23/2006 Physician United States
Primary
Concomitant
Pain 53 Female 12/8/2006 Consumer United States
Primary
Secondary
Concomitant
Pregnancy Test False Positive Other Serious 11/28/2006 53 Female 161 lb 12/27/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2002 Female 4/5/2007 Switzerland
Primary
Secondary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Visual Field Defect Other Serious 4/1/2008 Male 163 lb 9/5/2008 Pharmacist France
Primary
Secondary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 2/21/2009 United States
Primary
Concomitant
Wound Treatment Other Serious 2/17/2003 Male 297 lb 2/24/2009 United States
Primary
Concomitant
Wound Treatment Other Serious 2/17/2003 Male 297 lb 2/24/2009 United States
Primary
Concomitant
Tooth Abscess Other Serious 12/1/2005 Female 7/29/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 11/23/2008 Female 7/30/2009 Physician United States
Primary
Concomitant
Pyrexia Other Serious 3/26/2009 Female 127 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 12/30/2009 Physician United States
Primary
Concomitant
Pancreatitis Acute Life Threatening 10/1/2009 Female 1/8/2010 Physician United Kingdom
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 4/19/2008 Female 200 lb 1/18/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 12/28/2009 Male 210 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 12/22/2009 Female 161 lb 2/8/2010 Physician France
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 11/18/2009 75 Male 183 lb 3/16/2010 Germany
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 Male 174 lb 3/22/2010 United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/1/2010 70 Male 181 lb 5/18/2010 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 6/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 61 Female 203 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 6/11/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/13/2010 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/1/2010 79 Female 125 lb 7/21/2010 Physician United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 4/21/2010 83 Male 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pollakiuria Hospitalization 4/21/2010 83 Male 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Tooth Loss Disability 4/22/2010 73 Male 8/20/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Loss Other Serious Male 8/20/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 8/23/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 9/8/2010 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 7/30/2010 57 Male 9/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 9/30/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 1/7/2004 47 Female 10/5/2010 United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/8/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/11/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Tooth Loss Other Serious Male 10/11/2010 United States
Primary
Concomitant
Tooth Loss Other Serious Male 10/13/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/13/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 7/6/2009 64 Male 10/25/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 10/26/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/26/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection 73 Female 10/13/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 11/8/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/12/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/16/2010 United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 9/25/2010 66 Male 235 lb 11/16/2010 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 11/17/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 2/2/2004 75 Male 11/18/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/3/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 12/7/2010 Other Health Professional United States
Primary
Concomitant
Tooth Loss Other Serious 7/6/2009 64 Male 12/16/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 2/2/2004 75 Male 12/22/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 12/28/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/30/2010 United States
Primary
Secondary
Concomitant
Ligament Sprain Hospitalization 1/1/2005 63 Male 177 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Metabolic Syndrome Hospitalization 6/1/2006 47 Female 1/26/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Male 2/23/2011 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2005 63 Male 177 lb 2/28/2011 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 6/1/2006 78 Male 200 lb 3/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arteriosclerosis Hospitalization 6/1/2006 78 Male 200 lb 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 1/1/2003 46 Male 3/11/2011 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 63 Male 177 lb 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Oral Herpes Hospitalization 3/1/2011 69 Male 3/22/2011 Other Health Professional Netherlands
Primary
Concomitant
Abdominal Pain Upper Death 6/1/2006 78 Male 200 lb 3/28/2011 Physician United States
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 3/14/2011 53 Male 231 lb 3/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Paraesthesia Death 6/1/2006 78 Male 200 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Serology Positive Other Serious 5/7/2005 58 Male 174 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Sinusitis Hospitalization 6/1/2006 47 Female 4/6/2011 Lawyer United States
Primary
Concomitant
Urinary Retention Other Serious 6/1/2006 78 Male 200 lb 4/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 3/14/2011 53 Male 231 lb 4/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Groin Pain Hospitalization Male 4/18/2011 Other Health Professional Netherlands
Primary
Concomitant
Hyponatraemia Hospitalization 11/12/2010 72 Male 4/21/2011 Other Health Professional France
Primary
Concomitant
Malaise Hospitalization Male 4/21/2011 Netherlands
Primary
Concomitant
Death Death Male 4/25/2011 Physician United States
Primary
Concomitant
Osteolysis Other Serious 1/1/2006 42 Female 5/5/2011 Other Health Professional United States
Primary
Concomitant
Hyperglycaemia Death 1/1/2005 63 Male 216 lb 5/23/2011 United States
Primary
Secondary
Concomitant
Cough Death 1/1/2005 63 Male 216 lb 7/25/2011 United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 7/6/2009 64 Male 8/17/2011 Physician United States
Primary
Concomitant
Joint Effusion Other Serious Female 8/18/2011 Other Health Professional United States
Primary
Concomitant
Impaired Healing Other Serious Female 8/19/2011 Lawyer United States
Primary
Concomitant
Back Pain Other Serious 10/1/2003 70 Male 8/31/2011 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious Female 8/30/2011 Other Health Professional United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 184 lb 8/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Hospitalization 6/22/2011 Female 8/31/2011 Physician Cyprus
Primary
Concomitant
Spinal Fracture Hospitalization Male 154 lb 8/31/2011 Consumer Germany
Primary
Concomitant
Diverticulum Other Serious Female 138 lb 10/28/2011 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious Female 10/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Other Serious Female 208 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Infection Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Aortic Valve Incompetence Other Serious Male 184 lb 11/23/2011 Lawyer United States
Primary
Secondary
Concomitant
Osteolysis Other Serious 5/1/2007 41 Female 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious Male 12/27/2011 Physician United States
Primary
Concomitant
Fall Hospitalization Male 1/19/2012 Lawyer United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 12/28/2009 72 Male 210 lb 2/1/2012 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Disability 6/1/2006 47 Female 3/14/2012 Consumer United States
Primary
Concomitant
Bone Pain Hospitalization 10/1/2003 70 Male 3/14/2012 Physician United States
Primary
Secondary
Concomitant
Constipation 1/1/2012 69 Male 225 lb 6/11/2012 Consumer United States
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 81 Male 8/3/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence 1/1/2012 69 Male 227 lb 8/8/2012 Consumer United States
Primary
Secondary
Concomitant
Costochondritis Other Serious 1/1/2008 42 Female 8/23/2012 Physician United States
Primary
Concomitant
Weight Decreased Death 2006 Female 9/11/2012 Consumer Us
Primary
Concomitant
Weight Decreased Hospitalization 12/7/2009 70 Male 94 lb 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Rash Pruritic 6/2011 72 Male 207 lb 12/19/2012 Other Health Professional Us
Primary
Concomitant
Vertigo 2012 69 Male 229 lb 10/25/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Hypotension Other Serious Male 8/29/2012 Consumer De
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Death 2004 Male 10/3/2012 Other Health Professional No
Primary
Concomitant
Acute Coronary Syndrome Death 7/3/2012 67 Male 141 lb 12/27/2012 Other Health Professional Ru
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/31/2012 75 Male 182 lb 10/19/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 8/6/2012 77 Male 201 lb 10/24/2012 Physician Au
Primary
Secondary
Concomitant
Cellulitis Other Serious 9/20/2012 70 Female 131 lb 11/6/2012 Physician Us
Primary
Concomitant
Weight Decreased Hospitalization 7/6/2012 85 Female 123 lb 11/6/2012 Consumer Us
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/28/2011 60 Male 216 lb 11/6/2012 Consumer Us
Primary
Secondary
Concomitant
Wound Hospitalization 10/2007 Female 10/19/2012 Consumer Us
Primary
Secondary
Concomitant
Vertebral Foraminal Stenosis Other Serious 5/2000 Male 10/16/2012 Consumer Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2005 Female 10/30/2012 Physician Us
Primary
Concomitant
Wound Hospitalization Female 9/7/2012 Physician Us
Primary
Secondary
Concomitant

Drug Data