Metformin combined with Zolpidem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Troponin Increased Hospitalization 55 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Road Traffic Accident Death 1/25/2006 48 Male 3/6/2006 United States
Primary
Concomitant
Troponin Increased Hospitalization 55 Female 3/15/2006 Pharmacist United States
Primary
Secondary
Weight Increased Other Serious 3/1/2008 75 Female 181 lb 7/10/2008 Physician France
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 7/28/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 5/12/2007 Male 210 lb 1/14/2009 Physician United States
Primary
Concomitant
Poisoning Death 37 Male 1/15/2009 Physician United States
Primary
Secondary
Completed Suicide Death 37 Male 1/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/12/2009 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 2/20/2009 Physician United States
Primary
Concomitant
Product Quality Issue 7/1/2008 62 Female 2/27/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 3/5/2009 Physician United States
Primary
Concomitant
Somnolence Hospitalization 2/3/2009 73 Female 4/7/2009 Physician Switzerland
Primary
Concomitant
Interacting
Sleep Disorder Other Serious 5/1/2009 60 Male 6/16/2009 United States
Primary
Secondary
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/1/2003 45 Male 296 lb 7/29/2009 United States
Primary
Concomitant
Epilepsy Other Serious 1/1/2003 38 Female 160 lb 7/27/2009 United States
Primary
Concomitant
Social Problem Death 82 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 72 Female 7/22/2009 United States
Primary
Concomitant
Thyroidectomy Hospitalization 8/1/2008 Female 8/5/2009 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 7/1/2008 62 Female 8/6/2009 Pharmacist South Africa
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/20/2009 Female 11/5/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Radius Fracture Other Serious 8/9/2006 Female 11/9/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Death Death 1/4/2010 Female 1/14/2010 United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 56 Male 1/15/2010 Physician United States
Primary
Secondary
Renal Failure Hospitalization 9/29/2009 Male 210 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 62 Male 229 lb 1/22/2010 United States
Primary
Concomitant
Death Death Male 2/3/2010 Consumer United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 12/22/2009 Female 161 lb 2/8/2010 Physician France
Primary
Secondary
Concomitant
Completed Suicide Death 12/1/2009 56 Male 2/1/2010 Physician United States
Primary
Secondary
Liver Injury Hospitalization 1/18/2010 88 Female 2/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2009 87 Male 190 lb 4/6/2010 Pharmacist France
Primary
Secondary
Concomitant
Intestinal Ulcer Hospitalization 4/24/2009 84 Female 161 lb 4/22/2010 Physician Germany
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Rash 2/1/2010 38 Female 4/19/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 50 Female 230 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Erosion Hospitalization 1/1/2009 71 Male 240 lb 5/5/2010 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 3/27/2010 43 Male 6/16/2010 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Other Serious 1/1/2009 56 Male 203 lb 6/27/2010 Physician France
Primary
Secondary
Concomitant
Panic Attack Other Serious 5/19/2008 58 Female 8/5/2010 Lawyer United States
Primary
Concomitant
Flushing Female 195 lb 8/27/2010 United States
Primary
Concomitant
Musculoskeletal Discomfort 9/1/2009 65 Female 178 lb 8/27/2010 United States
Primary
Concomitant
Diarrhoea 2/3/2010 40 Female 8/28/2010 United States
Primary
Concomitant
Wheezing Other Serious 3/1/2004 42 Female 285 lb 9/3/2010 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 77 Male 9/2/2010 Physician United States
Primary
Secondary
Pain In Extremity 6/14/2010 70 Female 9/14/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2009 57 Male 9/17/2010 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 77 Male 8/31/2010 Physician United States
Primary
Secondary
Renal Failure Hospitalization 1/1/2008 46 Female 309 lb 10/4/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 10/18/2010 43 Female 10/29/2010 Physician United States
Primary
Concomitant
Poor Quality Sleep 10/19/2010 72 Female 138 lb 11/1/2010 Consumer United States
Primary
Concomitant
Interacting
Poor Quality Sleep 10/19/2010 72 Female 138 lb 12/1/2010 Physician United States
Primary
Concomitant
Interacting
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Completed Suicide Death 45 Female 1/21/2011 Physician United States
Primary
Secondary
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Dysphonia 1/1/2006 70 Female 147 lb 1/30/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious 1/1/1984 74 Male 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 12/1/2010 65 Female 180 lb 2/4/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Hospitalization 8/1/2010 55 Female 230 lb 2/3/2011 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/31/2011 66 Male 209 lb 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis Other Serious 11/15/2004 42 Female 285 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Movement Disorder Hospitalization Female 300 lb 2/23/2011 Consumer United States
Primary
Secondary
Concomitant
Nerve Injury Other Serious 1/27/2011 58 Female 2/25/2011 Consumer United States
Primary
Concomitant
Fungal Infection Hospitalization 12/1/2010 65 Female 180 lb 2/28/2011 Consumer United States
Primary
Concomitant
Cholecystitis Chronic Other Serious 7/8/2008 21 Female 262 lb 3/3/2011 Lawyer United States
Primary
Concomitant
Akathisia Other Serious 1/1/1984 32 Female 115 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Abdominal Wall Haematoma Hospitalization 1/24/2011 84 Female 3/29/2011 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 2/21/2011 59 Female 245 lb 4/1/2011 Physician France
Primary
Secondary
Concomitant
Drug Screen Positive 6/11/2010 42 Male 200 lb 4/4/2011 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/5/2010 51 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity 60 Male 4/4/2011 Pharmacist United States
Primary
Concomitant
Anaemia Hospitalization 1/24/2011 84 Female 4/11/2011 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 1/24/2011 84 Female 4/13/2011 Other Health Professional France
Primary
Concomitant
Interacting
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 44 Female 243 lb 4/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 50 Male 4/5/2011 United Kingdom
Primary
Concomitant
Abdominal Pain 1/11/2011 61 Male 4/15/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Female 4/21/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased 2/18/2011 64 Male 183 lb 4/26/2011 Consumer United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/1/2011 50 Male 4/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Injury Other Serious 1/1/2010 27 Female 323 lb 5/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/24/2011 84 Female 6/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Motor Dysfunction Other Serious 58 Male 6/14/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Hepatic Steatosis Hospitalization 1/1/2009 62 Female 8/2/2011 Physician Switzerland
Primary
Secondary
Concomitant
Depression Hospitalization 1/1/2009 58 Female 8/3/2011 Lawyer United States
Primary
Concomitant
Irritability Other Serious 6/1/2011 51 Female 154 lb 8/12/2011 Physician Colombia
Primary
Concomitant
Cognitive Disorder Hospitalization 1/1/2009 58 Female 8/26/2011 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Death 5/1/2011 70 Male 9/1/2011 Consumer United States
Primary
Concomitant
Pain In Extremity 6/14/2010 70 Female 9/6/2011 Consumer United States
Primary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Other Serious 1/1/2011 84 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 1/1/2011 84 Female 9/19/2011 Other Health Professional France
Primary
Concomitant
Interacting
Suicidal Ideation Other Serious 6/1/2011 51 Female 154 lb 9/21/2011 Physician Colombia
Primary
Concomitant
Polydipsia 64 Female 285 lb 9/22/2011 United States
Primary
Concomitant
Obesity 1/1/2006 30 Male 200 lb 9/22/2011 United States
Primary
Concomitant
Drug Hypersensitivity Male 185 lb 10/28/2011 Physician United States
Primary
Concomitant
Drug Hypersensitivity Male 185 lb 11/11/2011 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious Female 11/23/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/3/2011 75 Female 11/25/2011 Physician Spain
Primary
Secondary
Concomitant
Drug Effect Decreased 1/1/2012 63 Female 182 lb 1/19/2012 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Disability 5/1/2000 51 Female 182 lb 2/2/2012 Other Health Professional United States
Primary
Concomitant
Memory Impairment Female 3/1/2012 Physician United States
Primary
Concomitant
Emotional Distress Other Serious 3/1/2008 47 Female 3/26/2012 Lawyer United States
Primary
Concomitant
Somnolence Hospitalization 1/12/2012 77 Male 4/3/2012 Other Health Professional France
Primary
Concomitant
Drug Ineffective Disability 5/1/2000 51 Female 170 lb 4/25/2012 Other Health Professional United States
Primary
Concomitant
Haemorrhage Other Serious 2/1/2012 69 Male 215 lb 5/8/2012 Consumer United States
Primary
Concomitant
Infection Hospitalization 2/24/2012 67 Female 5/25/2012 Other Health Professional United States
Primary
Concomitant
Malaise Male 8/23/2012 Physician United States
Primary
Concomitant
Tendon Disorder Hospitalization 1/2008 Female 176 lb 10/22/2012 Consumer Us
Primary
Concomitant
Interacting
Weight Increased 66 Female 200 lb 3/7/2013 Us
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 11/3/2011 75 Female 3/21/2013 Physician Es
Primary
Secondary
Concomitant
Injection Site Pain Other Serious Female 1/25/2013 Consumer Br
Primary
Concomitant
Rash Hospitalization Female 8/31/2012 Pharmacist Us
Primary
Concomitant
Weight Increased 2012 Female 142 lb 11/22/2012 Consumer Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/1/2012 50 Female 223 lb 10/5/2012 Physician Us
Primary
Concomitant
Death Death 8/19/2012 57 Male 8/29/2012 Other Health Professional Us
Primary
Concomitant
Pancreatitis Hospitalization 8/13/2012 61 Male 218 lb Other Health Professional Us
Primary
Concomitant
Vomiting Other Serious 5/2012 Male 233 lb 11/26/2012 Physician Us
Primary
Concomitant
Sinus Tachycardia 61 Male 9/28/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 10/6/2011 53 Female 205 lb 10/19/2012 Physician Us
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 10/11/2012 56 Male 3/5/2013 Physician Us
Primary
Concomitant
Deep Vein Thrombosis Other Serious 8/9/2007 46 Female 10/24/2012 Other Health Professional Us
Primary
Concomitant
Myalgia 59 Female 200 lb 10/24/2012 Physician Us
Primary
Concomitant
Weight Increased 51 Female 10/25/2012 Physician Us
Primary
Concomitant
Gait Disturbance 59 Female 195 lb 12/3/2012 Consumer Us
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/23/2012 64 Female 157 lb 11/28/2012 Physician Us
Primary
Concomitant
Drug Ineffective 11/7/2012 50 Male 11/26/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Convulsion Other Serious 10/25/2012 64 Female 157 lb 11/28/2012 Physician Us
Primary
Concomitant
Pneumonia Death 55 Female 12/28/2012 Other Health Professional Us
Primary
Concomitant
International Normalised Ratio Increased Other Serious 11/28/2012 75 Male 160 lb 12/5/2012 Pharmacist Us
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 8/2/2012 86 Female 12/13/2012 Physician De
Primary
Concomitant
Vomiting Other Serious 10/15/2012 71 Female 195 lb 12/26/2012 Consumer Se
Primary
Concomitant
Drug Administration Error Female 1/7/2013 Physician Us
Primary
Concomitant
Toxicity To Various Agents Death 31 Female 1/10/2013 Physician Us
Primary
Secondary
Drug Ineffective Other Serious 1/5/2011 62 Female 220 lb 2/28/2013 Consumer Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/4/2012 51 Female 197 lb 2/25/2013 Other Health Professional Us
Primary
Concomitant
Respiratory Arrest Death 2011 70 Male 1/8/2013 Physician Us
Primary
Secondary
Tardive Dyskinesia Disability Female 1/17/2013 Physician Us
Primary
Concomitant
Completed Suicide Death 70 Male 1/18/2013 Physician Country Not Specified
Primary
Secondary
Rheumatoid Arthritis Other Serious 2009 61 Female 1/18/2013 Consumer Country Not Specified
Primary
Concomitant
Completed Suicide Other Serious 70 Male 1/20/2013 Physician Us
Primary
Secondary
Completed Suicide Death 27 Male 1/28/2013 Country Not Specified
Primary
Secondary
Death Death 10/22/2012 68 Male 1/28/2013 Physician Us
Primary
Concomitant
Poor Venous Access Other Serious 2012 Female 150 lb 9/17/2012 Consumer Us
Primary
Concomitant
Renal Failure Acute Hospitalization 7/23/2012 75 Male 10/29/2012 Physician Se
Primary
Secondary
Concomitant
Drug Ineffective 2012 59 Female 195 lb 10/30/2012 Consumer Us
Primary
Concomitant

Drug Data