Metformin combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Acuity Reduced Other Serious 1/1/2003 59 Male 1/10/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Disability 78 Male 1/12/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/25/2005 Male 181 lb 2/2/2006 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/25/2005 Male 180 lb 2/2/2006 Other Health Professional
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 11/1/2005 81 Female 2/15/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 6/25/2005 Male 225 lb 11/4/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/20/2001 64 Female 121 lb 2/24/2006 Lawyer United States
Primary
Concomitant
Erectile Dysfunction 11/1/2005 70 Male 12/28/2005 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 10/1/2005 81 Male 195 lb 1/20/2006 United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/30/2006 72 Male 146 lb 3/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased 8/1/2005 51 Male 210 lb 1/20/2006 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Drug Ineffective Hospitalization 2/1/2006 62 Female 218 lb 3/17/2006 Consumer United States
Primary
Concomitant
Leukopenia Other Serious 6/1/2005 53 Male 220 lb 3/28/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/29/1999 70 Male 209 lb 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2005 59 Male 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased 1/1/2005 54 Female 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Visual Disturbance 11/8/2005 65 Male 340 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 11/16/2005 63 Male 1/20/2006 Other Health Professional United States
Primary
Concomitant
Pain 12/10/2005 51 Female 215 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence 10/4/2005 64 Female 175 lb 1/20/2006 Consumer United States
Primary
Concomitant
Flatulence 11/1/2005 77 Male 260 lb 1/20/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2006 62 Female 218 lb 3/30/2006 Physician United States
Primary
Concomitant
Sinusitis 10/7/2005 45 Female 248 lb 1/20/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/10/2006 39 Female 4/12/2006 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/7/2006 Female 180 lb 4/19/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/2/2004 63 Male 231 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Myalgia Disability 65 Female 160 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2000 64 Female 121 lb 4/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/1999 57 Female 5/2/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2005 56 Female 216 lb 4/26/2006 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2000 64 Male 4/19/2006 Consumer United States
Primary
Secondary
Concomitant
Syncope 2/6/2006 61 Male 5/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Exacerbated 1/7/2006 60 Female 2/21/2006 United States
Primary
Concomitant
Syncope Hospitalization 2/6/2006 61 Male 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2005 85 Female 5/10/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 5/30/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 59 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Medication Error Life Threatening 6/1/2006 61 Male 6/5/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/25/2005 Male 181 lb 6/8/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Other Serious 10/1/2005 79 Female 170 lb 4/20/2006 United States
Primary
Concomitant
Somnolence Other Serious 1/27/2006 78 Female 4/20/2006 United States
Primary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 6/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 4/21/2005 50 Female 299 lb 5/18/2006 Physician United States
Primary
Concomitant
Vomiting 12/1/2005 63 Male 185 lb 4/17/2006 Consumer United States
Primary
Concomitant
Pain 11/29/2005 51 Female 212 lb 4/17/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2006 50 Female 4/17/2006 Consumer United States
Primary
Concomitant
Stress 1/23/2006 55 Female 169 lb 4/17/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 74 Female 6/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Swelling 47 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 7/13/2005 82 Female 7/21/2006 Consumer United States
Primary
Concomitant
Vision Blurred 8/1/2005 75 Female 7/21/2006 Consumer United States
Primary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/1/2005 68 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Oedema 50 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 60 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 54 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 57 Female 198 lb 7/7/2006 Physician United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/28/2005 53 Female 110 lb 7/18/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/10/2006 36 Female 143 lb 7/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence 1/1/2006 37 Male 193 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 6/6/2006 60 Male 180 lb 8/1/2006 United States
Primary
Concomitant
Insomnia 9/21/2005 63 Female 7/12/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 6/1/2006 45 Male 276 lb 8/14/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/9/2006 57 Female 213 lb 8/10/2006 Other Health Professional United States
Primary
Concomitant
Thrombosis Hospitalization 8/14/2006 71 Male 8/17/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 7/1/2006 71 Male 8/21/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/25/2005 Male 181 lb 9/12/2006 Other Health Professional Japan
Primary
Concomitant
Weight Increased Other Serious 60 Female 230 lb 9/8/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/10/2006 74 Female 187 lb 9/6/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Disability 8/1/2006 71 Female 9/26/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 12/18/2005 Male 194 lb 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 9/27/2006 66 Female 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2006 71 Female 115 lb 10/24/2006 Physician United States
Primary
Concomitant
Headache Other Serious 7/1/2006 62 Female 154 lb 10/30/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/10/2006 62 Female 210 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Pruritus 7/22/2005 50 Female 244 lb 11/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Decreased Life Threatening 10/1/2006 72 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Nightmare Other Serious 11/1/2006 64 Male 11/22/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2006 37 Female 194 lb 11/27/2006 Physician United States
Primary
Concomitant
Fatigue Disability Male 11/29/2006 Physician United States
Primary
Concomitant
Serum Ferritin Decreased Life Threatening 10/1/2006 72 Male 11/29/2006 Other Health Professional United States
Primary
Concomitant
Subileus Hospitalization 1/1/2005 69 Male 12/1/2006 Physician Spain
Primary
Concomitant
Serum Ferritin Decreased Life Threatening 10/1/2006 72 Male 12/1/2006 Other Health Professional United States
Primary
Concomitant
Swelling Face Hospitalization 1/1/2002 50 Female 12/13/2006 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 12/18/2005 Male 194 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Decreased Life Threatening 10/1/2006 72 Male 12/21/2006 Other Health Professional United States
Primary
Concomitant
Myalgia Hospitalization 12/16/2006 65 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Muscular Weakness Other Serious 1/8/2007 81 Male 1/18/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 9/3/2006 Female 1/25/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 12/1/2006 65 Male 172 lb 1/26/2007 Physician United States
Primary
Concomitant
Weight Decreased 7/12/2006 77 Male 160 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 2/13/2007 48 Female 337 lb 3/15/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Hospitalization 2/13/2007 48 Female 337 lb 3/15/2007 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 7/1/2006 76 Male 195 lb 11/28/2006 United States
Primary
Concomitant
Syncope Hospitalization 2/13/2007 Male 194 lb 3/29/2007 United States
Primary
Concomitant
Rash 12/1/2006 57 Male 2/16/2007 United States
Primary
Concomitant
Nausea 2/7/2007 37 Female 252 lb 5/17/2007 Physician United States
Primary
Concomitant
Drug Ineffective 2/23/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 6/13/2007 Female 112 lb 7/2/2007 Physician Israel
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 4/13/2007 55 Male 280 lb 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 8/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/1/2007 Female 250 lb 8/16/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Dose Omission Other Serious 1/1/2007 Male 245 lb 8/29/2007 Consumer United States
Primary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Myalgia 9/1/2007 64 Female 207 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Diarrhoea 55 Male 8/16/2007 Physician United States
Primary
Concomitant
Myalgia 4/15/2007 54 Female 185 lb 8/16/2007 Physician United States
Primary
Concomitant
Rash Macular 3/12/2007 65 Female 136 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia 60 Female 8/16/2007 United States
Primary
Concomitant
Headache 2/15/2007 51 Male 280 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2004 76 Male 10/23/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 2/16/2006 Female 170 lb 10/22/2007 Consumer United States
Primary
Concomitant
Cough 8/20/2007 Female 10/24/2007 Consumer United States
Primary
Concomitant
Dyspnoea 9/1/2006 67 Female 185 lb 10/25/2007 Consumer United States
Primary
Concomitant
Nervousness 5/19/2007 Male 10/26/2007 Consumer United States
Primary
Concomitant
Acute Promyelocytic Leukaemia Hospitalization 9/1/2004 54 Male 262 lb 12/26/2007 Pharmacist United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/1/2007 66 Male 12/28/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/18/2008 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 2/16/2006 Female 170 lb 1/11/2008 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/25/2008 Other Health Professional Canada
Primary
Concomitant
Tendon Rupture Hospitalization 1/1/2008 60 Male 198 lb 2/20/2008 Other Health Professional France
Primary
Concomitant
Tendon Rupture Hospitalization 1/1/2008 60 Male 198 lb 3/13/2008 Other Health Professional France
Primary
Concomitant
Somnolence Hospitalization 12/18/2005 74 Male 206 lb 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Event Other Serious 1/1/2007 Female 195 lb 3/13/2008 Consumer United States
Primary
Concomitant
Nasal Congestion 1/1/2008 64 Male 3/17/2008 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Disability 1/1/2007 66 Male 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Disability 10/1/2007 Male 174 lb 4/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Eruption Disability 10/1/2007 59 Female 201 lb 4/1/2008 Physician United States
Primary
Concomitant
Hepatomegaly Other Serious 4/8/2008 53 Male 260 lb 4/22/2008 Physician Cyprus
Primary
Concomitant
Hepatomegaly Other Serious 4/8/2008 53 Male 260 lb 5/1/2008 Physician Cyprus
Primary
Concomitant
Poor Quality Sleep Other Serious 1/1/2008 63 Male 223 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Disability 9/1/2007 75 Male 258 lb 5/14/2008 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 11/14/2007 41 Male 5/16/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Hospitalization 6/1/2006 49 Female 5/22/2008 Physician New Zealand
Primary
Concomitant
Tendonitis Other Serious 4/22/2008 49 Female 190 lb 6/19/2008 United States
Primary
Concomitant
Alopecia 2/1/2007 66 Female 127 lb 6/19/2008 Consumer United States
Primary
Concomitant
Migraine Hospitalization 3/1/2008 Female 6/17/2008 Physician United States
Primary
Concomitant
Rash Macular Other Serious 2/1/2008 79 Male 172 lb 6/23/2008 Physician United States
Primary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/2/2006 69 Female 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/1/2008 66 Male 7/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 11/14/2007 41 Male 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 3/22/2008 86 Male 200 lb 5/4/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Disability 6/1/2008 74 Female 7/9/2008 Consumer United States
Primary
Concomitant

Drug Data