Metformin combined with Xarelto

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastritis Other Serious 3/10/2011 82 Male 172 lb 3/21/2011 Pharmacist Canada
Primary
Concomitant
Interacting
Intracardiac Thrombus Other Serious 5/14/2012 67 Male 187 lb 8/22/2012 Physician United States
Primary
Concomitant
Expired Drug Administered 2011 68 Male 222 lb 7/4/2013 Consumer Us
Primary
Concomitant
Intracardiac Thrombus Other Serious 3/8/2012 71 Male 10/4/2012 Physician Us
Primary
Concomitant
Weight Increased Other Serious 2010 65 Female 197 lb 8/7/2013 Consumer Us
Primary
Secondary
Concomitant
Lung Disorder Disability 4/26/2012 82 Female 141 lb 11/19/2012 Physician Us
Primary
Concomitant
Deep Vein Thrombosis Postoperative Hospitalization 3/29/2010 72 Male 190 lb 8/29/2012 Physician Fr
Primary
Concomitant
Weight Decreased Hospitalization 4/2012 Male 11/21/2012 Other Health Professional De
Primary
Concomitant
Oropharyngeal Pain Other Serious 7/2012 Male 205 lb 12/19/2012 Consumer Us
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 7/4/2012 75 Female 163 lb 9/4/2012 Pharmacist Us
Primary
Concomitant
Subdural Haematoma Life Threatening 6/5/2012 80 Male 146 lb 9/10/2012 Other Health Professional Us
Primary
Concomitant
Interacting
Sensorimotor Disorder Other Serious 9/3/2012 86 Male 161 lb 9/18/2012 Physician De
Primary
Concomitant
Tongue Disorder Other Serious 8/2012 62 Female 9/26/2012 Physician Us
Primary
Concomitant
Torsade De Pointes Hospitalization 7/13/2012 72 Female 119 lb 7/13/2012 Pharmacist Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/2012 Female 250 lb 12/19/2012 Physician Us
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/14/2012 Male 212 lb 3/20/2013 Physician De
Primary
Concomitant
Heart Rate Increased Other Serious 10/2/2012 68 Female 270 lb 10/10/2012 Consumer Us
Primary
Concomitant
Procedural Site Reaction Hospitalization 2012 67 Female 10/19/2012 Physician Br
Primary
Concomitant
Interacting
Haemorrhage Intracranial Other Serious 10/2012 Male 11/16/2012 Physician Us
Primary
Concomitant
Procedural Site Reaction Other Serious 2012 67 Female 11/5/2012 Physician Br
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 10/18/2012 62 Male 212 lb 10/30/2012 Consumer Us
Primary
Concomitant
Kidney Infection Hospitalization Female 99 lb 11/5/2012 Consumer Mx
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/2012 Female 240 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Hospitalisation Hospitalization 10/2012 Male 12/3/2012 Physician Us
Primary
Concomitant
Hospitalisation Hospitalization 10/2012 82 Male 11/14/2012 Other Health Professional Us
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/15/2012 67 Female 240 lb 12/13/2012 Consumer Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/1/2012 86 Male 165 lb 11/29/2012 Physician De
Primary
Secondary
Drug Ineffective Other Serious 10/23/2012 65 Female 265 lb 1/21/2013 Physician De
Primary
Secondary
Concomitant
Haemorrhage Other Serious 11/4/2012 73 Female 2/26/2013 Physician De
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 2010 Male 216 lb 11/26/2012 Consumer Us
Primary
Concomitant
Drug Dose Omission Other Serious 9/28/2012 66 Female 11/28/2012 Pharmacist Us
Primary
Concomitant
Thyroiditis Other Serious 75 Male 11/29/2012 Physician Us
Primary
Concomitant
Drug Ineffective Life Threatening 11/11/2012 68 Male 154 lb 11/29/2012 Physician De
Primary
Concomitant
Thrombosis Other Serious 10/22/2012 46 Male 300 lb 11/29/2012 Other Health Professional Us
Primary
Concomitant
Postmenopausal Haemorrhage Hospitalization 11/3/2012 54 Female 12/19/2012 Physician De
Primary
Concomitant
Drug Ineffective Other Serious 11/7/2012 56 Female 12/4/2012 Physician Za
Primary
Concomitant
Pruritus 5/7/2012 69 Female 11/28/2012 Pharmacist Us
Primary
Concomitant
Pulmonary Embolism Other Serious 2012 53 Female 12/14/2012 Other Health Professional Us
Primary
Concomitant
Transaminases Increased Other Serious 8/2/2012 86 Female 12/13/2012 Physician De
Primary
Concomitant
Hearing Impaired Hospitalization 10/9/2012 73 Female 154 lb 2/13/2013 Other Health Professional Gb
Primary
Concomitant
Melaena Other Serious 12/2012 73 Male 185 lb 12/20/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Scratch Other Serious 2012 Male 265 lb 1/10/2013 Consumer Us
Primary
Secondary
Concomitant
Scratch Other Serious 2012 72 Male 265 lb 12/23/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Multi-organ Failure Death 12/20/2012 40 Male 218 lb 1/4/2013 Consumer Mx
Primary
Concomitant
Shock Hospitalization 12/21/2012 88 Male 186 lb 1/1/2013 Pharmacist Us
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/2013 Female 1/23/2013 Consumer Us
Primary
Concomitant
Haematoma Hospitalization 9/5/2012 79 Male 247 lb 1/28/2013 Physician De
Primary
Concomitant
Renal Failure Acute Other Serious 1/3/2013 88 Female 112 lb 1/29/2013 Physician Gb
Primary
Concomitant
Lacunar Infarction Life Threatening 1/11/2013 67 NotSpecified 251 lb 2/7/2013 Other Health Professional Gb
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 1/2013 Female 3/7/2013 Physician Us
Primary
Concomitant
Menorrhagia Hospitalization 1/3/2013 Female 265 lb 2/11/2013 Consumer Br
Primary
Secondary
Concomitant
Haemorrhage Urinary Tract Other Serious 12/2012 69 Male 204 lb 2/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Syncope Other Serious 2/4/2012 Female 190 lb 1/29/2013 Consumer Pr
Primary
Concomitant
Vasculitis Hospitalization 11/8/2012 75 Male 2/28/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 1/16/2013 71 Male 231 lb 4/12/2013 Physician De
Primary
Concomitant
Haemoglobin Decreased Life Threatening 6/2012 Male 3/12/2013 Physician Ca
Primary
Concomitant
General Physical Health Deterioration Death 12/7/2012 73 Male 2/20/2013 Physician De
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization Female 165 lb 3/15/2013 Physician Us
Primary
Concomitant
Prothrombin Time Prolonged Other Serious Female 154 lb 3/21/2013 Physician De
Primary
Secondary
Concomitant
Haemorrhage Urinary Tract Other Serious 11/28/2012 NotSpecified 2/11/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 2/4/2013 79 Female 3/12/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Renal Impairment Other Serious 76 Female 143 lb 5/6/2013 Pharmacist Gb
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 10/3/2012 76 Male 230 lb 3/7/2013 Consumer Us
Primary
Concomitant
Syncope Other Serious 1/21/2013 Male 3/6/2013 Consumer De
Primary
Concomitant
Subdural Haematoma Hospitalization 12/25/2012 68 Female 3/11/2013 Consumer Fr
Primary
Concomitant
Tension Other Serious 2/2013 63 Female 180 lb 5/22/2013 Consumer Us
Primary
Concomitant
Stomach Mass Other Serious 2/19/2013 79 Female 126 lb 4/5/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2013 78 Female 3/18/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Renal Failure Hospitalization Male 5/16/2013 Physician Us
Primary
Secondary
Concomitant
Pain Other Serious Female 122 lb 4/17/2013 Physician Country Not Specified
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 1/29/2013 78 Female 3/26/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/2013 59 Male 4/18/2013 Other Health Professional Us
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 1/24/2012 74 Female 150 lb 5/6/2013 Physician De
Primary
Concomitant
Ischaemic Stroke Disability 3/15/2013 70 Male 5/6/2013 Physician Us
Primary
Concomitant
Product Quality Issue Hospitalization 3/2013 59 Male 4/1/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 2/4/2013 78 Female 4/11/2013 Physician De
Primary
Concomitant
Renal Failure Hospitalization 1/31/2013 86 Male 160 lb 2/8/2013 Pharmacist Us
Primary
Concomitant
Hyperglycaemia Hospitalization 11/2012 58 Male 4/15/2013 Other Health Professional Fr
Primary
Concomitant
Drug Effect Decreased 67 Male 217 lb 4/15/2013 Consumer Us
Primary
Concomitant
Crying 3/21/2013 67 Male 217 lb 6/4/2013 Consumer Us
Primary
Concomitant
Myalgia Other Serious Male 212 lb 4/16/2013 Other Health Professional Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/2/2013 75 Female 287 lb 4/18/2013 Physician De
Primary
Concomitant
Lethargy Hospitalization Female 194 lb 4/18/2013 Physician Gb
Primary
Concomitant
Procedural Haemorrhage Hospitalization 3/29/2013 81 Male 174 lb 5/3/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Procedural Haemorrhage Hospitalization 3/29/2013 81 Male 174 lb 5/6/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Nephrolithiasis Other Serious 67 Male 225 lb 4/23/2013 Consumer Us
Primary
Concomitant
Renal Failure Acute Hospitalization 3/13/2013 72 Female 165 lb 6/19/2013 Physician De
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 4/4/2013 73 Male 225 lb 5/1/2013 Consumer Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 65 Female 139 lb 5/2/2013 Pharmacist Us
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/4/2013 72 Male 225 lb 5/3/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 4/19/2013 51 Female 375 lb 6/19/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Swelling Face Other Serious 3/4/2013 70 Male 192 lb 6/12/2013 Consumer De
Primary
Concomitant
Thrombosis Other Serious Female 5/13/2013 Physician Us
Primary
Concomitant
Thrombocytopenia Hospitalization 5/1/2013 56 Male 6/12/2013 Physician Us
Primary
Secondary
Concomitant
Haemorrhagic Transformation Stroke Hospitalization Male 8/4/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 5/1/2013 56 Male 5/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 76 Female 251 lb 5/20/2013 Pharmacist Gb
Primary
Concomitant
Skin Discolouration Other Serious 3/13/2013 78 Male 216 lb 5/20/2013 Other Health Professional Gb
Primary
Concomitant
Retinopathy Other Serious 4/2013 48 Male 209 lb 6/14/2013 Physician De
Primary
Secondary
Asthenia Other Serious 4/13/2013 59 Female 138 lb 5/21/2013 Consumer Us
Primary
Concomitant
Incorrect Dose Administered Hospitalization 5/12/2013 63 Male 5/22/2013 Other Health Professional Us
Primary
Concomitant
Hypoaesthesia 2012 Female 140 lb 5/23/2013 Consumer Us
Primary
Secondary
Concomitant
Sensory Disturbance Life Threatening Male 209 lb 6/3/2013 Physician De
Primary
Concomitant
Pleural Effusion Other Serious 8/2012 85 Male 185 lb 8/16/2013 Physician De
Primary
Concomitant
Ischaemic Cerebral Infarction Hospitalization 4/22/2013 71 Female 205 lb 6/14/2013 Physician De
Primary
Concomitant
Glycosylated Haemoglobin Decreased Other Serious 2013 69 Male 9/23/2013 Consumer Us
Primary
Concomitant
Skin Discolouration Other Serious 6/1/2013 79 Male 179 lb 6/24/2013 Consumer De
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/2013 77 Male 175 lb 7/5/2013 Consumer Us
Primary
Concomitant
Ear Pain 6/3/2013 80 Female 179 lb 6/18/2013 Consumer Us
Primary
Concomitant
Haemoptysis Disability 2013 78 Male 163 lb 8/22/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/5/2013 67 Female 6/20/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/28/2013 70 Male 6/20/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/14/2013 77 Male 6/20/2013 Other Health Professional Us
Primary
Concomitant
Haemorrhagic Transformation Stroke Other Serious 67 Male 7/5/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Drug Ineffective Other Serious 6/10/2013 80 Male 194 lb 7/1/2013 Physician Es
Primary
Concomitant
Wound Haemorrhage Other Serious 6/2013 68 Male 211 lb 8/23/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Eye Pain Other Serious Female 7/3/2013 Other Health Professional Us
Primary
Concomitant
Chest Pain Other Serious 4/2013 62 Female 7/3/2013 Other Health Professional Us
Primary
Concomitant
Anaemia Hospitalization 5/27/2013 88 Male 185 lb 7/4/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/31/2013 86 Male 160 lb 8/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Photopsia Other Serious 6/7/2013 76 Male 251 lb 7/25/2013 Physician De
Primary
Concomitant
Transient Ischaemic Attack Death 6/10/2013 79 Female 7/11/2013 Physician No
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 7/3/2013 77 Female 167 lb 8/20/2013 Pharmacist Us
Primary
Concomitant
Pericardial Haemorrhage Hospitalization 6/18/2013 67 Male 8/6/2013 Other Health Professional Us
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 86 Male 9/20/2013 Physician Ca
Primary
Concomitant
Thrombocytopenia Other Serious 6/27/2013 83 Female 143 lb 7/24/2013 Physician De
Primary
Concomitant
Weight Decreased Hospitalization 2013 71 Male 290 lb 7/24/2013 Consumer Us
Primary
Concomitant
Constipation 7/19/2013 73 Female 195 lb 7/25/2013 Other Health Professional Us
Primary
Concomitant
Puncture Site Haemorrhage Death 7/15/2013 78 Female 150 lb 7/23/2013 Registered Nurse Us
Primary
Concomitant
Weight Increased Other Serious 2013 76 Male 7/29/2013 Consumer Us
Primary
Secondary
Concomitant
Blood Glucose Increased Male 260 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Shock Other Serious 7/14/2013 79 Female 150 lb 8/30/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/31/2013 86 Male 160 lb 8/2/2013 Pharmacist Us
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 7/23/2013 83 Male 162 lb 8/27/2013 Physician Us
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 7/2013 71 Male 194 lb 8/14/2013 Physician De
Primary
Concomitant
Uterine Haemorrhage Other Serious 4/20/2013 72 Female 172 lb 8/12/2013 Physician De
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/31/2013 39 Female 8/13/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Haemorrhagic Stroke Other Serious 7/7/2013 70 Male 207 lb 12/10/2013 Physician Br
Primary
Concomitant
Headache Other Serious 52 Male 268 lb 8/15/2013 Other Health Professional Gb
Primary
Concomitant
Starvation Hospitalization 7/2013 89 Male 190 lb 8/16/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 7/24/2013 Female 10/7/2013 Physician Ca
Primary
Concomitant
Weight Decreased Other Serious 70 Female 230 lb 8/22/2013 Consumer Us
Primary
Concomitant
Nausea 7/2/2012 65 Male 8/22/2013 Consumer Us
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 2013 68 Female 180 lb 8/23/2013 Consumer Us
Primary
Concomitant
Local Swelling Hospitalization 7/22/2013 69 Male 198 lb 8/23/2013 Other Health Professional Gb
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 7/25/2013 75 Female 154 lb 9/23/2013 Physician Us
Primary
Secondary
Concomitant
Umbilical Hernia Repair Other Serious 8/19/2013 66 Male 10/9/2013 Consumer Us
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Other Serious 6/5/2013 81 Female 157 lb 10/16/2013 Physician Gb
Primary
Concomitant
Syncope Hospitalization 6/10/2013 77 Male 192 lb 12/23/2013 Physician De
Primary
Concomitant
Pulmonary Oedema Hospitalization 8/21/2013 74 Male 249 lb 10/4/2013 Pharmacist Gb
Primary
Concomitant

Drug Data