Metformin combined with Xalatan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Field Defect Disability 5/12/2005 57 Male 5/11/2006 Netherlands
Primary
Concomitant
Sputum Discoloured Hospitalization 5/4/2006 50 Female 5/19/2006 Pharmacist United States
Primary
Concomitant
Injection Site Bruising 8/8/2005 76 Female 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Rash 5/29/2005 67 Female 7/21/2006 Consumer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 92 Female 7/17/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 1/13/2007 Male 1/25/2007 Pharmacist Canada
Primary
Concomitant
Restlessness Life Threatening 4/17/2007 72 Female 174 lb 5/7/2007 Pharmacist United States
Primary
Concomitant
Hypotension 5/1/2007 72 Female 8/16/2007 Physician United States
Primary
Concomitant
Flushing 9/6/2006 66 Male 225 lb 9/20/2007 Other Health Professional United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/1/2007 Female 168 lb 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/6/2007 60 Male 11/11/2007 United States
Primary
Concomitant
Throat Irritation 2/1/2008 61 Male 220 lb 6/18/2008 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 10/30/2008 Male 183 lb 12/29/2008 Canada
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2006 Female 1/13/2009 Consumer
Primary
Concomitant
Swelling Face 12/7/2008 72 Female 170 lb 1/15/2009 Consumer United States
Primary
Concomitant
Tendon Disorder Disability 75 Male 209 lb 1/22/2009 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 7/1/2005 49 Male 359 lb 1/23/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 48 Male 241 lb 1/26/2009 Consumer United States
Primary
Concomitant
Increased Appetite Other Serious 12/1/2008 72 Female 215 lb 2/9/2009 United States
Primary
Concomitant
Wound Infection Other Serious 10/30/2008 Male 183 lb 3/6/2009 Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/11/2009 62 Male 179 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation 2/1/2009 80 Male 5/15/2009 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 12/1/2008 Male 6/3/2009 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 4/22/2002 Female 169 lb 6/24/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 8/25/2009 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 9/14/2009 Consumer United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2009 Female 9/29/2009 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 92 10/1/2009 Consumer Brazil
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 10/13/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 92 10/16/2009 Consumer Brazil
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/22/2009 Male 165 lb 10/20/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2006 Female 150 lb 11/4/2009 Consumer United States
Primary
Concomitant
Skin Burning Sensation 9/1/2009 Female 159 lb 11/25/2009 United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 12/11/2009 Physician United States
Primary
Concomitant
Vertigo Other Serious Male 2/2/2010 Consumer France
Primary
Concomitant
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 2/11/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 8/3/2009 Male 278 lb 2/12/2010 Physician Denmark
Primary
Concomitant
Intraocular Pressure Increased Other Serious 60 Female 130 lb 3/19/2010 Consumer Brazil
Primary
Concomitant
Palpitations Other Serious 1/1/2010 69 Male 165 lb 4/2/2010 Consumer Sweden
Primary
Concomitant
Upper Limb Fracture Other Serious 9/1/2009 77 Female 4/8/2010 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Cerebrovascular Accident Life Threatening 6/29/2009 67 Male 148 lb 4/23/2010 Physician France
Primary
Concomitant
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 4/22/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Weight Decreased Other Serious Male 198 lb 4/23/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/11/2009 71 Female 184 lb 6/29/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 1/1/2009 73 Male 163 lb 7/8/2010 Consumer Brazil
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 5/16/2010 70 Female 7/12/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/1/2009 74 Male 7/13/2010 Physician France
Primary
Concomitant
Nervousness Other Serious 1/1/2010 84 Male 174 lb 7/23/2010 Consumer Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/20/2006 84 Male 174 lb 8/10/2010 Physician Brazil
Primary
Concomitant
Visual Impairment Other Serious 1/1/2009 73 Male 163 lb 8/17/2010 Consumer Brazil
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2009 73 Male 163 lb 8/24/2010 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting 1/1/2008 53 Female 169 lb 8/28/2010 United States
Primary
Concomitant
Eye Irritation 7/1/2010 82 Female 130 lb 8/31/2010 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization Male 9/13/2010 Other Health Professional United States
Primary
Concomitant
Low Density Lipoprotein Increased 5/1/2010 59 Female 240 lb 9/16/2010 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/3/2010 80 Male 152 lb 9/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 7/3/2010 80 Male 152 lb 9/28/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Weight Increased Other Serious Female 9/21/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 48 Male 241 lb 10/7/2010 Pharmacist United States
Primary
Concomitant
Eye Irritation Male 175 lb 10/22/2010 Consumer United States
Primary
Secondary
Concomitant
Intraocular Pressure Decreased Other Serious 10/13/2010 69 Male 203 lb 10/27/2010 Consumer Brazil
Primary
Concomitant
Throat Irritation 72 Female 10/13/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious Male 11/2/2010 Consumer Netherlands
Primary
Concomitant
Intraocular Pressure Decreased Other Serious 10/13/2010 69 Male 203 lb 11/9/2010 Consumer Brazil
Primary
Concomitant
Gait Disturbance 11/2/2010 78 Male 193 lb 11/16/2010 Consumer United States
Primary
Concomitant
Eye Irritation Male 175 lb 12/10/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 86 Female 12/14/2010 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 11/5/2010 61 Male 1/12/2011 Physician United States
Primary
Concomitant
Dementia Other Serious 1/1/2010 83 Female 141 lb 1/20/2011 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 66 Male 198 lb 1/26/2011 Physician Hungary
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2011 78 Male 231 lb 1/26/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/29/2009 67 Male 148 lb 2/3/2011 Physician France
Primary
Concomitant
Abasia Other Serious Male 2/14/2011 Physician United States
Primary
Concomitant
Skin Discolouration 1/1/2009 70 Female 98 lb 2/16/2011 Consumer United States
Primary
Secondary
Concomitant
Expired Drug Administered 1/1/2010 57 Female 180 lb 2/17/2011 Consumer United States
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 1/3/2011 75 Female 194 lb 2/10/2011 Pharmacist United States
Primary
Concomitant
Nodal Arrhythmia Hospitalization 12/27/2010 81 Female 146 lb 1/26/2011 Pharmacist United States
Primary
Concomitant
No Adverse Event Female 141 lb 3/1/2011 Consumer United States
Primary
Concomitant
Death Death Male 3/8/2011 Consumer United States
Primary
Concomitant
Expired Drug Administered Other Serious 1/1/2011 78 Male 231 lb 3/17/2011 Consumer United States
Primary
Concomitant
Nephrogenic Anaemia Other Serious 9/19/2006 68 Male 3/22/2011 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2011 51 Male 212 lb 3/30/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/3/2010 80 Male 4/8/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/3/2010 80 Male 152 lb 4/8/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Abasia Other Serious 10/1/2009 70 Male 235 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2011 51 Male 212 lb 4/20/2011 Consumer United States
Primary
Secondary
Concomitant
Eye Irritation Other Serious 70 Male 4/20/2011 Consumer Netherlands
Primary
Concomitant
Death Death Male 4/22/2011 Consumer United States
Primary
Concomitant
Dyslipidaemia Other Serious 10/21/2009 57 Male 5/23/2011 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious Female 200 lb 6/6/2011 Consumer United States
Primary
Concomitant
Ocular Discomfort Other Serious 1/1/2011 71 Female 201 lb 6/6/2011 Consumer United States
Primary
Concomitant
Cataract Operation Other Serious 5/11/2011 74 Female 6/15/2011 Consumer Canada
Primary
Concomitant
Cataract Operation Other Serious 5/11/2011 75 Female 6/27/2011 Consumer Canada
Primary
Concomitant
Cataract Other Serious 1/1/2010 47 Female 6/28/2011 Consumer Canada
Primary
Concomitant
Confusional State Hospitalization 87 Female 7/5/2011 Physician Spain
Primary
Concomitant
Interacting
Parkinson's Disease Other Serious Male 7/21/2011 Consumer Canada
Primary
Concomitant
Parkinson's Disease Other Serious Male 8/2/2011 Consumer Canada
Primary
Concomitant
Glaucoma Surgery Other Serious 4/1/2010 75 Female 8/3/2011 Consumer Canada
Primary
Concomitant
Cataract Operation Other Serious 1/1/2010 Male 8/31/2011 Consumer Canada
Primary
Concomitant
Cataract Operation Other Serious 1/1/2009 72 Male 9/6/2011 Consumer Canada
Primary
Concomitant
Intraocular Pressure Increased Other Serious 67 Male 9/8/2011 Consumer Canada
Primary
Concomitant
Blindness Unilateral Other Serious 9/1/2010 Male 9/8/2011 Consumer Canada
Primary
Concomitant
Ocular Discomfort Other Serious 1/1/2011 71 Female 201 lb 9/15/2011 Consumer United States
Primary
Secondary
Concomitant
Blindness Unilateral Other Serious 9/1/2010 Male 9/21/2011 Consumer Canada
Primary
Concomitant
Intraocular Pressure Increased Other Serious 67 Male 9/23/2011 Consumer Canada
Primary
Concomitant
Cataract Operation Other Serious 1/1/2009 72 Male 9/28/2011 Consumer Canada
Primary
Concomitant
Intraocular Pressure Fluctuation Other Serious 1/1/2010 70 Male 9/30/2011 Consumer Canada
Primary
Concomitant
Dyspnoea Hospitalization 1/7/2011 66 Male 198 lb 10/11/2011 Physician Hungary
Primary
Concomitant
Sinus Disorder Other Serious 8/1/2007 69 Female 180 lb 10/20/2011 Consumer United States
Primary
Concomitant
Sinus Disorder Other Serious 8/1/2007 69 Female 180 lb 11/8/2011 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 155 lb 11/29/2011 Consumer Canada
Primary
Concomitant
Asthenopia Other Serious 8/1/2007 69 Female 180 lb 12/19/2011 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 155 lb 12/22/2011 Physician Canada
Primary
Concomitant
Eye Pain Other Serious 1/1/2012 64 Female 159 lb 1/17/2012 Consumer Brazil
Primary
Concomitant
Photopsia Other Serious 8/1/2011 80 Female 155 lb 1/27/2012 Consumer United States
Primary
Concomitant
Helicobacter Infection Other Serious 1/1/2010 Female 2/13/2012 Consumer Brazil
Primary
Secondary
Concomitant
Blindness Unilateral Other Serious 64 Female 2/29/2012 Consumer Brazil
Primary
Concomitant
Visual Impairment 57 Male 3/14/2012 United States
Primary
Secondary
Concomitant
Cataract Hospitalization 10/1/2010 70 Female 3/16/2012 Consumer Brazil
Primary
Concomitant
Intraocular Pressure Increased Other Serious 60 Male 3/20/2012 Consumer Brazil
Primary
Concomitant
Vitreous Floaters Other Serious 8/1/2011 80 Female 155 lb 3/20/2012 Other Health Professional United States
Primary
Concomitant
Salivary Hypersecretion Other Serious 1/1/2004 59 Male 161 lb 3/28/2012 Consumer Brazil
Primary
Concomitant
Depression Other Serious 1/1/2009 83 Female 4/18/2012 Consumer Brazil
Primary
Concomitant
Expired Drug Administered Other Serious 9/1/2011 84 Female 125 lb 5/10/2012 Consumer United States
Primary
Secondary
Concomitant
Infarction Hospitalization 5/1/2012 67 Male 5/16/2012 Consumer Brazil
Primary
Concomitant
Hypovolaemia Hospitalization 8/3/2009 70 Female 154 lb 5/24/2012 Pharmacist Germany
Primary
Concomitant
Interacting
Skin Exfoliation Other Serious 1/1/2012 75 Female 160 lb 5/25/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/3/2009 70 Female 154 lb 5/24/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Headache 3/1/2012 57 Female 215 lb 5/30/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/3/2009 70 Female 154 lb 6/5/2012 Pharmacist Germany
Primary
Concomitant
Interacting
Skin Exfoliation Other Serious 1/1/2012 75 Female 160 lb 6/11/2012 Physician United States
Primary
Secondary
Concomitant
Underdose Life Threatening 1/1/2006 59 Male 230 lb 6/15/2012 Consumer United States
Primary
Secondary
Concomitant
Emphysema Other Serious 6/18/2012 73 Female 214 lb 6/26/2012 Consumer United States
Primary
Secondary
Concomitant
Optic Nerve Disorder Other Serious 5/13/2012 75 Male 6/29/2012 Consumer Colombia
Primary
Concomitant
Gait Disturbance Other Serious 6/18/2012 73 Female 214 lb 7/10/2012 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 6/18/2012 73 Female 214 lb 7/16/2012 Consumer United States
Primary
Secondary
Concomitant
Headache 3/1/2012 57 Female 215 lb 7/27/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data