Metformin combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spinal Osteoarthritis Other Serious 9/22/2003 87 Female 95 lb 1/23/2006 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 7/1/1999 Male 209 lb 2/15/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 61 Female 227 lb 2/9/2006 Physician South Africa
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 4/2/2006 72 Female 157 lb 4/5/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2005 83 Female 3/30/2006 Pharmacist Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2006 83 Female 4/4/2006 Pharmacist Canada
Primary
Concomitant
Rash Hospitalization 3/21/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Bone Marrow Disorder Hospitalization 7/5/2006 79 Male 8/11/2006 Other Health Professional France
Primary
Concomitant
Acute Leukaemia Hospitalization 7/5/2006 79 Male 9/15/2006 Other Health Professional France
Primary
Concomitant
Chromaturia 4/1/2006 67 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2007 61 Female 3/7/2007 Physician United States
Primary
Concomitant
Rash Erythematous Hospitalization 3/1/2007 Male 4/11/2007 United Kingdom
Primary
Concomitant
Irritability Other Serious 4/1/2006 71 Male 231 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/23/2007 83 Male 10/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Disability 80 Male 168 lb 2/22/2008 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 6/1/2006 49 Female 5/22/2008 Physician New Zealand
Primary
Concomitant
Pallor Hospitalization 5/4/2008 78 Male 7/22/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/12/2009 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 2/20/2009 Physician United States
Primary
Concomitant
Generalised Erythema 11/22/2008 Male 2/24/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/4/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/26/2008 Male 255 lb 3/5/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/19/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 3/26/2009 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/25/1998 Female 141 lb 4/17/2009 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Hospitalization 49 Male 6/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 57 Male 6/17/2009 United States
Primary
Concomitant
Torsade De Pointes Other Serious 72 Female 6/25/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Haemorrhage Intracranial Hospitalization 64 Female 7/7/2009 United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 49 Male 7/9/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 45 Male 7/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 7/15/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 6/1/2008 76 Female 8/7/2009 Physician United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Pruritus 8/1/2008 Male 8/22/2009 Other Health Professional United States
Primary
Concomitant
Neck Pain Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 10/30/2008 Female 8/22/2009 United States
Primary
Concomitant
Flushing 1/1/2005 Male 8/22/2009 United States
Primary
Secondary
Concomitant
Heart Rate Increased 1/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 8/25/2009 Consumer United States
Primary
Concomitant
Stress Other Serious 1/1/2003 Male 212 lb 9/11/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 9/16/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 72 Female 9/21/2009 Other Health Professional United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 49 Male 9/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 49 Male 9/29/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2009 Male 200 lb 10/23/2009 Consumer United States
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2009 Male 200 lb 11/13/2009 Consumer United States
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 10/26/2009 Female 11/20/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Disorder Hospitalization 10/1/2009 59 Female 198 lb 1/1/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 5/1/2009 Female 1/5/2010 Physician United States
Primary
Concomitant
Sleep Disorder Life Threatening 10/1/2009 48 Male 353 lb 1/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Male 366 lb 1/21/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 57 Female 186 lb 1/25/2010 United States
Primary
Concomitant
Cardiac Disorder Hospitalization 11/1/2009 Male 165 lb 1/25/2010 Consumer Brazil
Primary
Concomitant
Respiratory Failure Other Serious 12/21/2007 64 Male 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious Female 2/19/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/15/2010 Male 267 lb 3/26/2010 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 4/19/2010 75 Male 5/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 4/19/2010 75 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/4/2010 66 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Premature Baby Other Serious 38 Male 5/31/2010 Consumer United States
Primary
Concomitant
Dyspepsia Other Serious 1/1/2002 64 Female 6/7/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious Female 247 lb 6/11/2010 Physician United Kingdom
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2007 60 Female 163 lb 6/16/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/11/2009 71 Female 184 lb 6/29/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 4/25/2010 73 Female 7/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mental Disorder Other Serious 2/26/2008 73 Male 7/16/2010 Lawyer United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 59 Male 328 lb 7/21/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Muscle Spasms Male 180 lb 8/16/2010 Consumer United States
Primary
Concomitant
Nausea Other Serious 12/1/2008 64 Male 8/23/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/27/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hepatic Neoplasm Other Serious 8/20/2010 82 Male 218 lb 9/1/2010 Consumer United States
Primary
Concomitant
Limb Crushing Injury Other Serious 1/1/1998 48 Male 350 lb 9/2/2010 Consumer United States
Primary
Concomitant
Drug Effect Decreased Other Serious 5/1/2010 69 Male 140 lb 9/3/2010 Consumer United States
Primary
Concomitant
Somnolence 4/3/2009 60 Female 180 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Clostridial Infection Hospitalization 5/24/2010 59 Male 206 lb 9/14/2010 Physician United States
Primary
Concomitant
Rash Pruritic 9/19/2010 71 Female 9/27/2010 Consumer
Primary
Concomitant
Lung Transplant Hospitalization 59 Male 195 lb 9/28/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 5/1/2010 47 Female 9/29/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization Male 240 lb 10/5/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 42 Female 211 lb 10/21/2010 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2009 64 Female 217 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 68 Male 179 lb 11/1/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Life Threatening 7/26/2010 70 Female 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sluggishness Hospitalization 3/1/2010 60 Female 152 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 10/1/2010 62 Male 260 lb 11/9/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 11/18/2010 Pharmacist United Kingdom
Primary
Concomitant
Malaise 6/4/2010 45 Female 175 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 12/7/2010 Pharmacist United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction 11/2/2010 54 Female 158 lb 11/5/2010 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 82 Female 11/30/2010 United States
Primary
Concomitant
Injection Site Haematoma 5/3/2010 12/22/2010 Consumer United States
Primary
Concomitant
Sinus Disorder 12/1/2010 80 Male 165 lb 12/24/2010 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 47 Male 300 lb 12/29/2010 Other Health Professional Canada
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2009 40 Female 311 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Application Site Pruritus Other Serious 12/1/2010 86 Male 168 lb 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Incorrect Dose Administered Other Serious 1/3/2011 68 Male 180 lb 1/16/2011 Consumer United States
Primary
Concomitant
Palpitations Other Serious 3/1/2008 50 Male 328 lb 1/20/2011 Physician United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 1/1/2005 43 Female 1/26/2011 Physician United States
Primary
Concomitant
Mental Status Changes Other Serious 62 Male 172 lb 1/28/2011 Other Health Professional
Primary
Concomitant
Wheezing 1/1/2008 70 Male 1/30/2011 Consumer United States
Primary
Concomitant
Wound Infection 10/1/2010 62 Female 102 lb 1/30/2011 Other Health Professional United States
Primary
Concomitant
Pain In Jaw 7/1/2010 72 Male 1/30/2011 Consumer United States
Primary
Concomitant
Arthralgia 7/1/2010 72 Male 1/30/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 8/9/2010 61 Female 1/30/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious 1/1/1984 74 Male 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Bundle Branch Block Left Other Serious 62 Female 331 lb 1/26/2011 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 80 Male 1/28/2011 United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/1/2009 35 Female 2/15/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2005 43 Female 2/17/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 1/24/2011 72 Male 2/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Disability 78 Female 1/13/2011 Physician Puerto Rico
Primary
Concomitant
Dyspnoea Death 10/1/2010 85 Female 110 lb 2/23/2011 Physician United States
Primary
Concomitant
Dysuria Other Serious 1/3/2011 68 Male 180 lb 2/23/2011 Consumer United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 65 Male 2/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 63 Male 200 lb 2/28/2011 Other Health Professional United States
Primary
Concomitant
Glossodynia 1/1/2010 Female 198 lb 3/1/2011 Consumer United States
Primary
Concomitant
Blood Calcium Decreased Other Serious 1/1/2011 73 Female 215 lb 3/3/2011 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 2/1/2011 73 Male 3/4/2011 Consumer United Kingdom
Primary
Concomitant
Oedema Hospitalization 1/24/2011 72 Male 3/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Localised Infection Other Serious 10/17/2010 67 Female 187 lb 3/7/2011 Physician Canada
Primary
Concomitant
Headache 12/13/2010 85 Female 3/10/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 1/1/2011 46 Female 3/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Abnormal Female 3/11/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 7/1/2009 35 Female 3/14/2011 Consumer United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 65 Male 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain 1/1/2010 Female 198 lb 3/17/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization Male 161 lb 3/4/2011 Consumer Canada
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 8/1/2009 65 Female 242 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 76 Male 3/30/2011 Consumer United States
Primary
Concomitant
Nausea 8/1/2009 37 Female 280 lb 4/4/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 80 Male 190 lb 4/5/2011 Lawyer United States
Primary
Concomitant
Skin Exfoliation Disability 2/18/2011 73 Female 3/29/2011 Other Health Professional Denmark
Primary
Concomitant
Foaming At Mouth 8/24/2010 63 Female 4/13/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/27/2009 35 Female 183 lb 4/13/2011 Lawyer United States
Primary
Concomitant
Sudden Death Death 11/20/2010 57 Male 229 lb 4/18/2011 Physician United Kingdom
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 1/1/2011 46 Female 214 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 7/17/2010 78 Male 4/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 64 Male 4/21/2011 Other Health Professional United States
Primary
Concomitant
Hallucination, Visual Other Serious 1/22/2011 77 Male 214 lb 4/14/2011 Consumer United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 2/18/2011 73 Male 194 lb 4/29/2011 Consumer United Kingdom
Primary
Concomitant
Pain Life Threatening 8/4/2005 73 Female 165 lb 4/29/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Male 5/2/2011 Pharmacist United States
Primary
Concomitant

Drug Data