Metformin combined with Vitamin B12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vitamin B12 Decreased Other Serious 1/1/2001 53 Female 185 lb 4/13/2006 United States
Primary
Concomitant
Vitamin B12 Decreased Other Serious 53 Female 185 lb 5/19/2006 Physician United States
Primary
Concomitant
Weight Decreased 2/1/2007 51 Female 169 lb 1/10/2008 Consumer United States
Primary
Concomitant
Thrombosis Other Serious Female 3/18/2013 Physician Us
Primary
Secondary
Concomitant
Interacting
Microangiopathic Haemolytic Anaemia Death 7/11/2010 57 Male 222 lb 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/2011 33 Female 5/1/2013 Consumer Ca
Primary
Concomitant
Suicidal Ideation Other Serious 6/21/2011 48 Male 250 lb 11/28/2013 Consumer Country Not Specified
Primary
Concomitant
Vomiting Other Serious Female 117 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Renal Failure Acute Hospitalization 8/6/2011 73 Female 216 lb 5/1/2013 Physician Us
Primary
Secondary
Concomitant
Nausea Other Serious 11/11/2011 66 Female 196 lb 3/11/2013 Other Health Professional Ca
Primary
Concomitant
Pneumonia Hospitalization 12/7/2011 66 Female 9/18/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Diverticulum Intestinal Haemorrhagic Other Serious 3/14/2012 76 Female 9/17/2013 Physician Ca
Primary
Concomitant
Pyrexia Hospitalization 3/28/2012 86 Female 115 lb 10/17/2012 Physician Us
Primary
Secondary
Concomitant
Myalgia 67 Female 4/9/2013 Physician Us
Primary
Secondary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 3/27/2012 69 Female 10/19/2012 Physician Ca
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 4/2010 39 Female 206 lb 12/12/2012 Physician Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2010 65 Female 197 lb 8/7/2013 Consumer Us
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/8/2011 71 Female 173 lb 3/2/2013 Consumer Us
Primary
Concomitant
Medication Error Other Serious 5/20/2012 68 Female 9/25/2012 Physician Us
Primary
Concomitant
Pancytopenia Hospitalization 4/2011 Female 8/29/2012 Physician Us
Primary
Concomitant
Multi-organ Failure Life Threatening 7/19/2012 50 Male 236 lb 11/9/2012 Physician Ca
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 4/26/2012 79 Female 170 lb 9/5/2012 Other Health Professional Us
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/22/2012 52 Female 275 lb 8/29/2012 Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/27/2012 53 Female 168 lb 1/25/2013 Consumer Country Not Specified
Primary
Concomitant
Irritability 8/23/2012 59 Female 269 lb 8/29/2012 Consumer Us
Primary
Secondary
Concomitant
Sedation 41 Female 9/3/2012 Physician Us
Primary
Concomitant
Septic Shock Other Serious 69 Female 8/30/2012 Physician Ca
Primary
Concomitant
Dysgeusia 7/2012 67 Male 240 lb 9/14/2012 Consumer Us
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2011 60 Male 1/7/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 12/16/2011 60 Male 239 lb 1/9/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 9/2012 Male 169 lb 10/5/2012 Other Health Professional Ca
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/2/2012 56 Female 260 lb 12/19/2012 Consumer Us
Primary
Concomitant
Trismus Other Serious Female 10/17/2012 Physician Us
Primary
Concomitant
Rhinitis 1/3/2012 71 Female 132 lb 10/24/2012 Physician Us
Primary
Concomitant
Rectal Polyp Hospitalization 8/2012 Female 10/25/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Initial Insomnia Other Serious 10/2/2012 64 Female 150 lb 10/24/2012 Consumer Us
Primary
Concomitant
Cerebrovascular Accident Disability 57 Female 10/31/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Urticaria Female 11/2/2012 Pharmacist Us
Primary
Concomitant
Vomiting Hospitalization 9/29/2012 53 Female 255 lb 11/1/2012 Consumer Us
Primary
Concomitant
Blood Glucose Decreased Male 617 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Gait Disturbance 59 Female 195 lb 12/3/2012 Consumer Us
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/20/2012 82 Female 211 lb 11/21/2012 Other Health Professional Ca
Primary
Concomitant
Pneumonia Other Serious 11/5/2012 63 Female 118 lb 1/23/2013 Consumer Country Not Specified
Primary
Concomitant
Angioedema Other Serious 11/15/2012 47 Female 177 lb 12/10/2012 Other Health Professional Gb
Primary
Concomitant
Headache 10/20/2012 83 Male 12/11/2012 Consumer Us
Primary
Concomitant
Nasopharyngitis 10/2012 54 Female 303 lb 12/14/2012 Consumer Us
Primary
Secondary
Concomitant
Throat Irritation Other Serious 11/2/2012 70 Female 206 lb 12/17/2012 Other Health Professional Us
Primary
Concomitant
Stomatitis Hospitalization 66 Male 12/27/2012 Other Health Professional Us
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 12/16/2011 60 Male 238 lb 1/9/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Nausea Female 158 lb 1/9/2013 Consumer Us
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/16/2011 60 Male 238 lb 1/10/2013 Physician Gb
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 12/27/2012 58 Female 1/14/2013 Consumer Us
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 1/2/2013 67 Male 198 lb 9/24/2013 Consumer Ca
Primary
Concomitant
Staphylococcal Skin Infection Disability 8/2012 72 Female 165 lb 1/15/2013 Physician Ca
Primary
Concomitant
Headache Female 1/18/2013 Consumer Us
Primary
Concomitant
Ulcer Hospitalization 7/2012 Male 141 lb 2/23/2013 Other Health Professional Us
Primary
Concomitant
Stomatitis Hospitalization 66 Male 1/22/2013 Physician Us
Primary
Secondary
Concomitant
Wound Other Serious Female 265 lb 6/21/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Injection Site Pain 1/5/2011 67 Female 145 lb 1/28/2013 Consumer Us
Primary
Concomitant
Vertigo 50 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriasis 2011 Male 165 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Tuberculosis 3/2010 62 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Chills 8/23/2012 53 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 265 lb 4/5/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/24/2012 68 Female 207 lb 4/3/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Wound 8/18/2012 62 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriasis 4/2012 54 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Syncope Other Serious 2/4/2012 Female 190 lb 1/29/2013 Consumer Pr
Primary
Concomitant
Injection Site Swelling 8/18/2012 60 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pain 2012 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Rash Papular 7/23/2012 62 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Joint Dislocation 6/2012 60 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pulmonary Hypertension Hospitalization Male 189 lb 1/29/2013 Consumer Us
Primary
Concomitant
Oropharyngeal Pain 10/2012 Female 251 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Rash 12/3/2012 50 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Dermatitis Infected Hospitalization 1/2013 Male 265 lb 2/18/2013 Consumer Country Not Specified
Primary
Concomitant
Vomiting 11/2012 62 Female 2/19/2013 Other Health Professional Us
Primary
Concomitant
Vomiting 2/5/2013 68 Female 172 lb 3/15/2013 Consumer Us
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Male 2/28/2013 Consumer Us
Primary
Concomitant
Bacterial Infection Death Male 172 lb 2/28/2013 Other Health Professional Ca
Primary
Concomitant
Fatigue 3/2012 Male 392 lb 3/4/2013 Consumer Us
Primary
Concomitant
Drug Ineffective 2012 71 Female 173 lb 3/4/2013 Consumer Us
Primary
Secondary
Concomitant
Aphagia 43 Male 218 lb 3/5/2013 Us
Primary
Secondary
Concomitant
Pain Disability 10/2011 63 Male 220 lb 3/27/2013 Consumer Us
Primary
Concomitant
Thyroid Neoplasm Other Serious 10/31/2012 53 Female 3/20/2013 Physician Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/28/2011 77 Female 175 lb 4/20/2013 Consumer Us
Primary
Concomitant
Epistaxis 2/20/2013 61 Female 192 lb 7/19/2013 Consumer Us
Primary
Concomitant
Haemorrhage Other Serious Female 6/27/2013 Other Health Professional Ca
Primary
Concomitant
Heart Rate Increased Other Serious 2/25/2013 77 Male 186 lb 3/14/2013 Other Health Professional Ca
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/16/2012 75 Male 198 lb 3/14/2013 Physician Country Not Specified
Primary
Concomitant
Drug Ineffective 2012 59 Female 195 lb 10/30/2012 Consumer Us
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 3/17/2011 77 Male 235 lb 8/29/2013 Consumer Us
Primary
Concomitant
Flushing 11/2012 Female 3/25/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 2/7/2013 61 Female 196 lb 3/28/2013 Other Health Professional Ca
Primary
Concomitant
Gastritis Other Serious 59 Male 5/6/2013 Physician Us
Primary
Concomitant
Renal Failure Acute Other Serious 62 Male 200 lb 4/10/2013 Physician Ca
Primary
Secondary
Concomitant
Skin Disorder 2013 58 Female 269 lb 8/15/2013 Consumer Us
Primary
Concomitant
Intentional Drug Misuse 4/2013 51 Female 150 lb 5/1/2013 Consumer Us
Primary
Concomitant
Syncope Other Serious 12/2012 54 Male 180 lb 5/10/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 2013 52 Female 7/1/2013 Consumer Us
Primary
Concomitant
Off Label Use Female 4/30/2013 Consumer Country Not Specified
Primary
Concomitant
Loss Of Consciousness Other Serious 12/2012 54 Male 180 lb 5/15/2013 Consumer Us
Primary
Concomitant
Interacting
Paraesthesia Disability 2003 54 Male 183 lb 5/20/2013 Consumer Gb
Primary
Secondary
Concomitant
Paraesthesia Disability 2003 54 Male 183 lb 5/21/2013 Consumer Gb
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2003 54 Male 183 lb 5/21/2013 Consumer Gb
Primary
Secondary
Concomitant
Paraesthesia Disability 2003 54 Male 183 lb 5/22/2013 Consumer Gb
Primary
Secondary
Concomitant
Local Swelling 2013 71 Female 161 lb 6/19/2013 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization 68 Male 176 lb 5/30/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Suicide Attempt Required Intervention 68 Male 176 lb 5/28/2013 Ca
Primary
Secondary
Concomitant
Joint Swelling Other Serious 3/2013 70 Male 159 lb 6/7/2013 Other Health Professional Us
Primary
Concomitant
Weight Decreased 50 Female 159 lb 6/20/2013 Physician Us
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/29/2013 81 Male 181 lb 8/13/2013 Physician Ca
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/6/2013 56 Female 255 lb 7/1/2013 Physician Us
Primary
Concomitant
Joint Swelling Other Serious 2013 Male 159 lb 6/12/2013 Other Health Professional Us
Primary
Concomitant
Drug Ineffective 60 Female 170 lb 6/14/2013 Consumer Us
Primary
Concomitant
Suicidal Ideation Other Serious 2/2013 Female 8/16/2013 Consumer Us
Primary
Concomitant
Vaginal Laceration Other Serious 11/2011 30 Female 165 lb 6/17/2013 Other Health Professional Us
Primary
Concomitant
Sinusitis 64 Female 194 lb 6/17/2013 Other Health Professional Us
Primary
Concomitant
Ear Pain 6/3/2013 80 Female 179 lb 6/18/2013 Consumer Us
Primary
Concomitant
Cardiac Disorder Other Serious 1/31/2013 85 Male 7/17/2013 Physician Country Not Specified
Primary
Concomitant
White Blood Cell Count Decreased Disability 12/16/2011 60 Male 238 lb 6/24/2013 Physician Ca
Primary
Secondary
Concomitant
Embolism Other Serious 91 Female 6/27/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 1/13/2013 65 Female 169 lb 6/25/2013 Us
Primary
Concomitant
Blood Pressure Increased Other Serious 7/17/2013 72 Female 7/31/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Palpitations 7/17/2013 30 Female 163 lb 7/24/2013 Consumer Us
Primary
Concomitant
Blood Glucose Increased NotSpecified 265 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Blood Glucose Increased Male 265 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Skin Burning Sensation Male 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Swelling Face 8/2012 59 Female 214 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Blood Pressure Increased Male 320 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Tachycardia 2013 Female 175 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Nausea NotSpecified 233 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Abdominal Pain Upper 4/8/2013 65 Female 198 lb 7/30/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Rhinorrhoea 6/2013 53 Female 8/1/2013 Other Health Professional Us
Primary
Concomitant
Pain In Extremity Other Serious 4/17/2013 56 Female 8/5/2013 Consumer Us
Primary
Concomitant
Sensation Of Heaviness Other Serious 56 Female 8/9/2013 Consumer Us
Primary
Concomitant
Incorrect Dose Administered Hospitalization Male 8/16/2013 Physician Us
Primary
Concomitant
Fall Hospitalization 8/8/2013 59 Female 98 lb 8/19/2013 Other Health Professional Ca
Primary
Concomitant
Pruritus Hospitalization Female 204 lb 8/22/2013 Consumer Us
Primary
Concomitant
Anaemia 5/16/2013 68 Male 235 lb 8/23/2013 Consumer Us
Primary
Concomitant
Pain 75 Female 117 lb 9/18/2013 Consumer Us
Primary
Concomitant
Blood Testosterone Decreased Male 8/28/2013 Consumer Country Not Specified
Primary
Concomitant
Blood Testosterone Decreased 3/2013 69 Male 259 lb 8/28/2013 Consumer Us
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 8/2013 Female 9/5/2013 Consumer De
Primary
Secondary
Vitamin B12 Deficiency Other Serious 8/2013 Female 9/5/2013 Consumer De
Primary
Secondary
Rash Generalised Other Serious 1/2012 76 Female 1/19/2012 Physician Us
Primary
Concomitant
Pollakiuria Other Serious 8/2013 66 Female 148 lb 9/27/2013 Consumer Us
Primary
Concomitant
Pneumonia Hospitalization 9/18/2013 74 Female 135 lb 10/30/2013 Us
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 11/6/2013 Consumer Us
Primary
Concomitant

Drug Data