Metformin combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 9/8/2004 Female 3/3/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased 7/1/2005 51 Female 179 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/8/2004 Female 3/28/2006 Physician Germany
Primary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2001 53 Female 185 lb 5/8/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/20/2006 74 Male 260 lb 5/5/2006 Physician United States
Primary
Concomitant
Weight Decreased 3/1/2006 50 Female 4/17/2006 Consumer United States
Primary
Concomitant
Injection Site Bruising 8/8/2005 76 Female 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Dry Mouth 2/27/2006 67 Female 4/17/2006 Consumer United States
Primary
Concomitant
Lethargy Hospitalization 5/16/2006 76 Female 6/27/2006 United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/16/2006 76 Female 7/6/2006 United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 2/1/2005 80 Female 7/21/2006 Consumer Canada
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 7/10/2006 74 Female 187 lb 9/6/2006 Other Health Professional United States
Primary
Concomitant
Nightmare Other Serious 11/1/2006 64 Male 11/22/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2006 54 Female 258 lb 11/20/2006 Consumer United States
Primary
Concomitant
Pubic Rami Fracture Other Serious 8/1/2006 66 Male 206 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 8/14/2006 66 Female 6/25/2007 United States
Primary
Concomitant
Pneumonia Other Serious 3/31/2007 85 Male 7/10/2007 Physician Norway
Primary
Secondary
Concomitant
Weight Decreased 11/7/2006 74 Female 260 lb 7/11/2007 Consumer United States
Primary
Concomitant
Polyarthritis Other Serious 9/19/2007 Male 10/24/2007 Physician Netherlands
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 120 lb 11/2/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 5/1/2005 Female 198 lb 6/5/2008 Physician United States
Primary
Concomitant
Drug Ineffective 5/2/2008 61 Female 7/24/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 280 lb 7/22/2008 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/4/2008 Female 178 lb 8/22/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 280 lb 8/19/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 8/30/2008 Female 9/9/2008 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2008 42 Female 190 lb 10/1/2008 United States
Primary
Concomitant
Convulsion Other Serious 9/3/2008 Female 10/28/2008 Physician United States
Primary
Concomitant
Otitis Media Hospitalization 10/25/2008 Male 180 lb 1/9/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 12/1/2008 Male 190 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 12/1/2008 Male 190 lb 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Male 2/24/2009 United States
Primary
Concomitant
Insomnia 9/2/2008 44 Female 3/4/2009 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 3/25/2009 Consumer United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2007 Female 180 lb 3/23/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2006 Male 165 lb 6/26/2009 Consumer United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 1/18/2009 62 Female 7/1/2009 Pharmacist Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/1/2009 Canada
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/23/2009 53 Female 7/7/2009 Other Health Professional Canada
Primary
Concomitant
Pain In Extremity Other Serious 2/20/2009 58 Male 7/21/2009 United States
Primary
Concomitant
Alveolitis Allergic Hospitalization 4/18/2009 Female 183 lb 7/29/2009 New Zealand
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/30/2009 55 Female 253 lb 7/23/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2006 Male 165 lb 8/3/2009 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 6/16/2009 Female 220 lb 8/17/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 Male 242 lb 8/19/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 6/1/2007 Female 160 lb 8/20/2009 Physician Canada
Primary
Concomitant
Alveolitis Allergic Hospitalization 4/18/2009 Female 183 lb 8/20/2009 New Zealand
Primary
Secondary
Concomitant
Feeling Hot 12/9/2008 Female 8/22/2009 United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2008 Male 170 lb 10/1/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 8/13/2009 67 Male 211 lb 9/25/2009 Pharmacist Canada
Primary
Concomitant
Pruritus 8/24/2009 Male 227 lb 11/25/2009 United States
Primary
Concomitant
Skin Tightness Female 11/25/2009 United States
Primary
Concomitant
Weight Decreased Disability 9/1/2009 77 Male 12/8/2009 Physician Colombia
Primary
Concomitant
Pyrexia Hospitalization 8/26/2009 67 Male 211 lb 12/14/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting 9/1/2009 Female 195 lb 10/27/2009 Consumer United States
Primary
Concomitant
Death Death 11/4/2009 66 Male 399 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 12/22/2009 United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 12/26/2009 Male 154 lb 1/7/2010 Physician India
Primary
Secondary
Concomitant
Large Intestinal Ulcer Hospitalization 11/18/2009 65 Female 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/26/2009 Male 154 lb 1/15/2010 Physician India
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 80 Male 1/7/2010 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious 12/1/2009 Female 1/31/2010 Other Health Professional Canada
Primary
Concomitant
Spinal Cord Disorder Hospitalization 6/25/2009 Female 209 lb 2/12/2010 Consumer United States
Primary
Concomitant
Pain 9/1/2009 66 Male 245 lb 2/15/2010 Consumer United States
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 2/19/2010 United States
Primary
Concomitant
Myalgia Other Serious 1/29/2010 Female 199 lb 3/9/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 3/12/2010 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/2/2009 67 Male 185 lb 4/5/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 4/22/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/8/2010 78 Female 4/27/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 68 Male 149 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Skin Reaction Other Serious Female 5/5/2010 Physician Canada
Primary
Concomitant
Pneumonia Other Serious 12/1/2009 60 Female 198 lb 5/7/2010 Other Health Professional Canada
Primary
Concomitant
Hyperosmolar State Other Serious 44 Male 5/3/2010 Physician United Kingdom
Primary
Concomitant
Blood Glucose Increased 1/1/2010 70 Female 168 lb 6/3/2010 United States
Primary
Concomitant
Chest Pain Other Serious 5/1/2010 64 Female 184 lb 6/4/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 6/11/2010 United States
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 6/18/2010 Consumer United States
Primary
Concomitant
Diarrhoea 10/1/2006 70 Male 165 lb 6/29/2010 Consumer United States
Primary
Concomitant
Urticaria Hospitalization Female 6/30/2010 United States
Primary
Concomitant
Rash 5/9/2007 62 Female 178 lb 7/13/2010 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles 1/1/1998 37 Female 7/14/2010 United States
Primary
Concomitant
Weight Decreased 12/12/2007 58 Male 220 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 2/1/2008 71 Female 185 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Middle Insomnia 3/15/2008 63 Female 168 lb 7/21/2010 Consumer United States
Primary
Concomitant
Pain Female 296 lb 8/4/2010 Consumer United States
Primary
Concomitant
Nausea 1/1/2003 67 Male 165 lb 8/6/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 8/5/2010 52 Female 8/25/2010 Consumer United States
Primary
Concomitant
Road Traffic Accident Life Threatening 8/17/2010 75 Male 172 lb 8/25/2010 Physician Canada
Primary
Secondary
Concomitant
Skin Reaction Other Serious Female 8/25/2010 Physician Canada
Primary
Concomitant
Muscular Weakness 7/30/2009 74 Male 232 lb 8/27/2010 United States
Primary
Concomitant
Flushing 1/1/2004 52 Male 290 lb 8/27/2010 United States
Primary
Concomitant
Flushing 8/8/2009 56 Male 220 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 10/12/2009 Female 8/28/2010 United States
Primary
Concomitant
Pruritus 10/1/2009 70 Female 115 lb 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2007 60 Female 185 lb 8/28/2010 United States
Primary
Concomitant
Pain 6/1/2009 69 Male 200 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 11/1/2009 67 Female 124 lb 8/28/2010 United States
Primary
Concomitant
Heart Rate Increased 2/1/2010 63 Male 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2010 62 Female 176 lb 8/28/2010 United States
Primary
Concomitant
Diarrhoea Female 156 lb 8/28/2010 United States
Primary
Concomitant
Paraesthesia 3/1/2010 57 Male 165 lb 8/28/2010 United States
Primary
Concomitant
Abdominal Discomfort Female 180 lb 8/29/2010 United States
Primary
Concomitant
Hyperhidrosis 5/18/2010 68 Female 242 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing 5/1/2010 66 Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Generalised Erythema 5/24/2010 46 Female 203 lb 8/29/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation 6/1/2010 72 Male 259 lb 8/29/2010 Consumer United States
Primary
Concomitant
Melaena 6/30/2010 76 Male 162 lb 8/29/2010 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 6/29/2010 63 Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Road Traffic Accident Life Threatening 8/17/2010 75 Male 172 lb 9/2/2010 Physician Canada
Primary
Secondary
Concomitant
Anaemia Hospitalization 8/3/2010 57 Male 222 lb 8/31/2010 Physician United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 8/3/2010 57 Male 223 lb 9/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization Male 222 lb 9/7/2010 Physician United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Nervousness 9/4/2010 65 Female 165 lb 9/16/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Female 152 lb 9/15/2010 Physician United States
Primary
Concomitant
Ventricular Extrasystoles 1/1/1998 37 Female 9/20/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/5/2010 68 Male 183 lb 9/22/2010 Physician United States
Primary
Concomitant
Pancreatic Mass Other Serious 7/29/2010 63 Female 201 lb 9/23/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1984 29 Male 315 lb 9/24/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1998 43 Male 315 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 7/1/2010 82 Female 165 lb 9/29/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 8/18/2010 75 Male 9/29/2010 Physician United States
Primary
Concomitant
Pancreatic Mass Other Serious 7/29/2010 63 Female 201 lb 10/5/2010 Physician United States
Primary
Concomitant
Catheterisation Cardiac Hospitalization Female 235 lb 10/6/2010 Physician United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/25/2010 10/8/2010 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/15/2009 73 Female 141 lb 10/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/8/2010 United States
Primary
Concomitant
Vomiting Hospitalization 8/31/2010 65 Male 10/7/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/5/2010 68 Male 183 lb 10/12/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1984 52 Male 315 lb 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 9/1/2010 75 Male 191 lb 10/13/2010 Physician United States
Primary
Concomitant
Jaundice Other Serious 10/1/2010 68 Male 10/21/2010 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 1/1/2010 72 Female 10/25/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 8/30/2010 66 Male 334 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Back Pain 81 Female 159 lb 10/26/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/26/2010 United States
Primary
Concomitant
Vomiting Other Serious 10/1/2010 68 Male 10/27/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 8/23/2010 58 Male 175 lb 10/28/2010 Consumer United States
Primary
Concomitant
Dyspnoea 76 Female 10/13/2010 Consumer United States
Primary
Concomitant
Haemorrhage Subcutaneous 77 Male 10/13/2010 Consumer United States
Primary
Concomitant
Tongue Discolouration 72 Female 10/13/2010 Consumer United States
Primary
Concomitant

Drug Data