Metformin combined with Trazodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hallucination, Visual Other Serious 9/1/2004 56 Female 1/5/2006 Consumer United States
Primary
Concomitant
Toe Amputation Hospitalization 9/1/2005 Female 220 lb 1/13/2006 United States
Primary
Concomitant
Prostate Examination Abnormal Hospitalization 10/1/2005 Male 253 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Other Serious 12/12/2005 Female 126 lb 1/31/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2009 Female 180 lb 2/27/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2009 Female 180 lb 3/23/2009 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/9/2009 Male 319 lb 6/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Disability 3/1/2009 Male 7/9/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/8/2009 Male 230 lb 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Disability 53 8/28/2009 Consumer Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 Male 131 lb 10/1/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/12/2005 53 Female 184 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Device Failure Other Serious 10/1/2009 50 Female 240 lb 10/7/2009 Consumer United States
Primary
Concomitant
Acquired Macroglossia Other Serious 9/11/2009 Female 188 lb 10/14/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 10/26/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2001 56 Male 256 lb 11/2/2009 United States
Primary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Vitreous Floaters Hospitalization 62 Female 12/11/2009 Lawyer United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 56 Male 1/15/2010 Physician United States
Primary
Secondary
Vaginal Haemorrhage Other Serious 1/1/1999 Female 197 lb 1/22/2010 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/1999 Female 197 lb 1/23/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 1/25/2010 United States
Primary
Concomitant
Intentional Self-injury Hospitalization Female 165 lb 2/12/2010 Other Health Professional Germany
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/2003 41 Male 256 lb 2/22/2010 United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 12/21/2009 Female 151 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/15/2010 Male 267 lb 3/26/2010 Pharmacist United States
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 4/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2009 62 Female 179 lb 5/4/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 5/1/2010 48 Male 226 lb 7/1/2010 Consumer United States
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 9/1/2009 7/22/2010 Other Health Professional United States
Primary
Concomitant
Headache 6/15/2008 Male 7/22/2010 Consumer United States
Primary
Concomitant
Cardiac Death Death Male 198 lb 7/23/2010 Physician Canada
Primary
Secondary
Concomitant
Stress Other Serious 7/9/2008 57 Female 212 lb 7/23/2010 Physician United States
Primary
Concomitant
Drug Ineffective Female 276 lb 7/31/2010 Physician United States
Primary
Concomitant
Hepatitis Acute Death 5/27/2010 92 Male 8/2/2010 Other Health Professional Italy
Primary
Concomitant
Drug Ineffective 4/1/2010 55 Male 238 lb 8/17/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2009 68 Female 167 lb 8/29/2010 Consumer United States
Primary
Concomitant
Acquired Macroglossia Other Serious 9/11/2009 62 Female 188 lb 9/16/2010 Physician United States
Primary
Concomitant
Speech Disorder Disability 53 Female 9/16/2010 Consumer Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 9/16/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1984 29 Male 315 lb 9/24/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1998 43 Male 315 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Other Serious 8/27/2010 60 Female 170 lb 9/29/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2009 68 Female 167 lb 10/15/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/6/2010 60 Female 170 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 9/3/2010 56 Female 209 lb 10/22/2010 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 1/1/2010 72 Female 10/25/2010 Physician United States
Primary
Concomitant
Rib Fracture Hospitalization 1/1/2010 61 Female 176 lb 10/25/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 10/29/2010 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 9/14/2010 63 Female 10/29/2010 Physician United States
Primary
Concomitant
Venous Injury Other Serious 9/16/2010 60 Male 324 lb 11/2/2010 Consumer United States
Primary
Concomitant
Paranoia Other Serious 9/1/2009 58 Male 149 lb 10/26/2010 United States
Primary
Secondary
Pulmonary Oedema Hospitalization 1/1/2010 63 Male 281 lb 11/11/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2005 62 Female 240 lb 11/9/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 63 Female 225 lb 11/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/13/2008 61 Female 200 lb 12/8/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious Male 261 lb 12/13/2010 Physician Canada
Primary
Concomitant
Acquired Macroglossia Other Serious 9/11/2009 62 Female 188 lb 10/14/2009 Physician United States
Primary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2010 67 Female 225 lb 12/20/2010 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 8/1/2010 77 Male 190 lb 12/27/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2010 67 Female 225 lb 12/29/2010 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 1/1/2010 72 Female 254 lb 1/11/2011 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2002 34 Female 205 lb 1/20/2011 Consumer United States
Primary
Concomitant
Bunion Other Serious 3/28/2003 44 Female 256 lb 1/20/2011 Consumer United States
Primary
Concomitant
Self Injurious Behaviour Other Serious 1/15/2011 42 Male 303 lb 1/24/2011 Consumer United States
Primary
Concomitant
Death Death Male 1/26/2011 Pharmacist Canada
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/21/2010 49 Female 324 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Bronchitis 1/1/2009 28 Female 273 lb 1/28/2011 Physician United States
Primary
Concomitant
Rash Other Serious 10/1/2009 50 Female 1/29/2011 Physician United States
Primary
Concomitant
Chest Pain 7/9/2010 58 Female 1/29/2011 Other Health Professional United States
Primary
Concomitant
Haematocrit Decreased 5/1/2009 Female 1/29/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Haemorrhagic 5/1/2009 40 Female 1/29/2011 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 6/1/2010 54 Male 260 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 11/12/2010 52 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 58 Male 1/30/2011 Consumer United States
Primary
Concomitant
Pain 12/8/2010 62 Male 1/30/2011 Consumer United States
Primary
Concomitant
Myalgia 8/1/2010 77 Male 190 lb 2/18/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2010 67 Female 225 lb 2/22/2011 Consumer United States
Primary
Secondary
Concomitant
Duodenal Perforation Other Serious 1/1/2009 69 Female 2/25/2011 Physician Canada
Primary
Concomitant
Drug Intolerance 3/1/2010 54 Female 245 lb 2/28/2011 Consumer United States
Primary
Concomitant
Dyspnoea 12/27/2010 57 Female 3/4/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 2/14/2011 45 Female 176 lb 3/4/2011 Physician United States
Primary
Concomitant
Feeding Tube Complication 73 Male 3/14/2011 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 2/11/2011 66 Male 338 lb 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Anxiety Other Serious Female 174 lb 3/14/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious Female 174 lb 3/14/2011 Consumer United States
Primary
Concomitant
Gallbladder Cholesterolosis Other Serious 2/19/2008 16 Female 210 lb 3/20/2011 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 2/16/2011 66 Male 338 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/17/2011 61 Female 220 lb 3/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 41 Female 186 lb 3/30/2011 Consumer United States
Primary
Concomitant
Pain Other Serious Female 4/8/2011 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/14/2010 68 Male 4/15/2011 Pharmacist United States
Primary
Concomitant
Malaise 4/1/2011 62 Male 157 lb 4/19/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/15/2007 60 Female 190 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
No Adverse Event 3/30/2011 55 Female 247 lb 4/12/2011 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/14/2010 68 Male 4/28/2011 Pharmacist United States
Primary
Concomitant
Constipation 4/14/2011 64 Female 190 lb 4/19/2011 Consumer United States
Primary
Concomitant
Dyspepsia Life Threatening 67 Female 4/29/2011 Consumer United States
Primary
Concomitant
Ulcer Other Serious 53 Male 5/2/2011 Physician United States
Primary
Secondary
Concomitant
Malaise 5/3/2011 63 Female 215 lb 5/5/2011 Consumer United States
Primary
Concomitant
Hostility Other Serious 1/1/2011 53 Female 145 lb 5/16/2011 Other Health Professional United States
Primary
Concomitant
Irritability Other Serious 1/1/2011 53 Female 145 lb 5/17/2011 Other Health Professional United States
Primary
Concomitant
Physical Assault Other Serious 1/1/2011 53 Female 143 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Dysuria Other Serious 1/1/2008 59 Male 205 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 5/1/2011 49 Female 190 lb 5/31/2011 Consumer United States
Primary
Concomitant
Malaise 4/1/2011 62 Male 157 lb 6/10/2011 Physician United States
Primary
Concomitant
Oscillopsia 6/9/2011 77 Female 6/16/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 5/16/2011 56 Female 172 lb 7/5/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 1/1/2007 52 Male 7/19/2011 Lawyer United States
Primary
Concomitant
Drug Effect Delayed 1/1/2011 52 Male 320 lb 7/21/2011 Consumer United States
Primary
Concomitant
Alopecia Other Serious 1/1/2011 42 Female 172 lb 7/22/2011 Consumer United States
Primary
Concomitant
Vision Blurred 6/9/2011 77 Female 7/25/2011 Consumer United States
Primary
Concomitant
Drug Level Increased Hospitalization 1/1/2011 55 Male 8/3/2011 Pharmacist Canada
Primary
Concomitant
Pain 8/2/2011 54 Female 175 lb 8/8/2011 Consumer United States
Primary
Concomitant
Mental Disorder Other Serious 1/1/2008 42 Male 8/10/2011 Lawyer United States
Primary
Concomitant
Vomiting 6/13/2006 29 Female 4/29/2008 Physician United States
Primary
Concomitant
Anxiety Other Serious 8/1/2007 61 Female 9/9/2011 Lawyer United States
Primary
Concomitant
Drug Ineffective Other Serious 11/22/2011 69 Female 150 lb 12/7/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 3/21/2011 32 Female 12/21/2011 Pharmacist United States
Primary
Concomitant
Pain Other Serious 1/1/2011 56 Male 258 lb 12/25/2011 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 50 Female 205 lb 1/11/2012 Consumer United States
Primary
Concomitant
Drug Level Decreased 1/19/2012 70 Female 160 lb 2/1/2012 Consumer United States
Primary
Concomitant
Impaired Work Ability Other Serious 2/7/2012 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 50 Female 205 lb 2/8/2012 Consumer United States
Primary
Concomitant
Uterine Disorder Other Serious 10/1/2011 51 Female 144 lb 2/9/2012 Consumer United States
Primary
Concomitant
Drug Level Decreased 1/19/2012 70 Female 161 lb 2/15/2012 Consumer United States
Primary
Concomitant
Irritability Other Serious 2/1/2012 46 Female 240 lb 2/22/2012 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 50 Female 205 lb 2/29/2012 Consumer United States
Primary
Concomitant
Pneumothorax Other Serious 10/1/2011 51 Female 144 lb 3/1/2012 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious Male 3/6/2012 Consumer United States
Primary
Concomitant
Corneal Transplant Other Serious Female 3/7/2012 Consumer United States
Primary
Secondary
Concomitant
Impaired Work Ability Other Serious 3/15/2012 Other Health Professional United States
Primary
Concomitant
Corneal Transplant Other Serious Female 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious Male 4/9/2012 Consumer United States
Primary
Secondary
Concomitant
Depression Other Serious 2/1/2012 46 Female 240 lb 4/9/2012 Consumer United States
Primary
Secondary
Concomitant
Cataract Other Serious Female 4/17/2012 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization Male 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2012 62 Male 240 lb 4/25/2012 Consumer United States
Primary
Concomitant
Malaise Male 143 lb 4/27/2012 Consumer United States
Primary
Concomitant
Erythema Other Serious 4/2/2012 55 Male 203 lb 4/27/2012 Pharmacist Canada
Primary
Concomitant
Physical Disability Disability 1/1/2012 62 Male 240 lb 4/30/2012 Consumer United States
Primary
Concomitant
Intervertebral Disc Disorder Other Serious Female 5/7/2012 Physician United States
Primary
Concomitant

Drug Data