Metformin combined with Tramadol Hcl

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hallucination, Visual Other Serious 9/1/2004 56 Female 1/5/2006 Consumer United States
Primary
Concomitant
Stomach Discomfort 11/1/2005 47 Male 3/7/2006 Consumer United States
Primary
Concomitant
Stomach Discomfort 11/1/2005 47 Male 3/7/2006 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 3/1/2003 47 Male 3/21/2006 Consumer United States
Primary
Concomitant
Asthenia Required Intervention 3/10/2006 75 Female 3/12/2006 Physician United States
Primary
Concomitant
Incorrect Drug Administration Rate Hospitalization 3/1/2004 Male 3/27/2006 New Zealand
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 4/13/2006 United States
Primary
Secondary
Concomitant
Pain Other Serious 9/1/2004 56 Female 4/21/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 Female 300 lb 5/2/2006 Consumer United States
Primary
Concomitant
Stridor Disability 2/24/2006 45 Female 5/8/2006 United States
Primary
Concomitant
Vomiting Hospitalization 4/12/2006 70 Male 6/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypernatraemia Required Intervention 62 Female 6/8/2006 Physician United States
Primary
Concomitant
Rash Pruritic 2/15/2006 63 Female 190 lb 4/17/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 2/27/2006 53 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Movement Disorder Hospitalization 6/1/2006 68 Female 236 lb 7/27/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 3/27/2006 72 Male 198 lb 8/14/2006 Physician Germany
Primary
Concomitant
Pituitary Infarction Other Serious 62 Female 10/23/2006 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 1/1/2006 80 Female 11/1/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/11/2004 46 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/24/2006 55 Female 11/14/2006 Consumer United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Throat Tightness 1/9/2006 Female 12/20/2006 Consumer United States
Primary
Concomitant
Carotid Artery Stenosis Hospitalization 9/21/2006 56 Male 225 lb 12/20/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 182 lb 3/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Hyperglycaemia Other Serious 10/19/2006 65 Female 4/23/2007 United States
Primary
Secondary
Concomitant
Restlessness Life Threatening 4/17/2007 72 Female 174 lb 5/7/2007 Pharmacist United States
Primary
Concomitant
Back Pain 11/7/2006 62 Female 183 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/4/2007 58 Male 261 lb 10/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 8/7/2007 57 Male 257 lb 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Pruritus Other Serious 2/12/2008 Female 203 lb 3/13/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/23/2008 54 Female 143 lb 3/14/2008 Consumer Mexico
Primary
Concomitant
Respiratory Tract Congestion 1/1/2007 Female 170 lb 3/15/2008 United States
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 256 lb 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 3/10/2008 Male 3/25/2008 Consumer Netherlands
Primary
Concomitant
Pulmonary Embolism Other Serious 3/12/2007 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/17/2008 Male 3/28/2008 Belgium
Primary
Concomitant
Thrombocythaemia Death 6/29/2008 Female 157 lb 7/23/2008 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 7/28/2008 Physician United Kingdom
Primary
Concomitant
Throat Cancer Other Serious 1/18/2008 Male 181 lb 8/22/2008 United Kingdom
Primary
Concomitant
Blood Thyroid Stimulating Hormone Increased 9/1/2007 Female 160 lb 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/3/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 220 lb 10/8/2008 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 10/15/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 10/22/2008 Female 1/12/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 12/26/2008 Male 164 lb 1/15/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 265 lb 1/21/2009 Lawyer United States
Primary
Concomitant
Completed Suicide Death 76 Male 1/29/2009 Other Health Professional United States
Primary
Secondary
Wound Hospitalization 1/1/2007 Female 1/30/2009 Other Health Professional Sweden
Primary
Concomitant
Myocardial Ischaemia Hospitalization 6/1/2005 33 Female 207 lb 2/4/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Other Serious 7/31/2008 Female 166 lb 2/19/2009 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/5/2008 Female 278 lb 2/27/2009 Consumer United Kingdom
Primary
Concomitant
Somnolence 4/1/2008 78 Female 3/4/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 9/1/2003 59 Male 226 lb 3/6/2009 Consumer United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Other Serious 7/29/2006 Female 166 lb 3/5/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 11/29/2007 Female 213 lb 3/6/2009 Physician United States
Primary
Concomitant
Medication Error 12/1/2008 67 Female 3/24/2009 Consumer
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 3/25/2009 United States
Primary
Concomitant
Lung Neoplasm Malignant Death 1/29/2009 Male 150 lb 3/27/2009 Consumer Brazil
Primary
Concomitant
Pruritus 4/7/2009 63 Female 6/9/2009 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Other Serious 10/15/2008 66 Male 201 lb 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/29/2006 Female 166 lb 5/29/2009 Physician United States
Primary
Concomitant
Paraesthesia Hospitalization 4/1/2009 Male 237 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 7/27/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/4/2009 Consumer
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Face 6/19/2008 Female 8/21/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 62 Female 9/15/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/25/2009 71 Male 174 lb 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/25/2009 Female 10/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 7/20/2009 Female 123 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 10/9/2009 United States
Primary
Concomitant
Death Death 9/25/2009 Female 10/20/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2003 62 Male 281 lb 10/21/2009 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Nausea Other Serious Male 182 lb 11/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious Male 182 lb 11/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 6/25/2009 Female 11/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2006 36 Female 263 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 59 Male 199 lb 12/29/2009 United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/3/2009 Female 12/29/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 12/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2009 64 Female 1/11/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2009 64 Female 1/13/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2008 Male 130 lb 3/11/2010 United States
Primary
Concomitant
Renal Injury Other Serious 7/1/2007 Male 201 lb 3/19/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/10/2010 78 Female 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 4/2/2010 43 Male 256 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 1/1/2010 66 Female 4/22/2010 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 212 lb 4/26/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 4/20/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 61 Female 203 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 64 Male 185 lb 7/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Loss Disability 4/22/2010 73 Male 8/20/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/27/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2010 82 Female 8/27/2010 Physician United States
Primary
Concomitant
Rash Macular Male 234 lb 8/28/2010 United States
Primary
Concomitant
Headache 2/1/2010 50 Female 288 lb 8/28/2010 United States
Primary
Concomitant
Pruritus Male 300 lb 8/29/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/26/2010 65 Male 8/30/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/2/2009 64 Male 9/2/2010 Physician
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Uterine Disorder Other Serious 3/21/2005 39 Female 211 lb 9/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2006 46 Male 249 lb 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
Interacting
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 286 lb 9/20/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 5/14/2007 58 Male 9/24/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/11/2006 46 Male 249 lb 9/21/2010 United States
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Swelling Other Serious 1/6/2008 34 Female 291 lb 10/1/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Male 249 lb 9/28/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 49 Male 10/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 7/1/2010 66 Female 10/6/2010 Other Health Professional United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/14/2007 58 Male 10/8/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 9/27/2010 88 Female 108 lb 10/14/2010 Physician Spain
Primary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Male 257 lb 10/18/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 7/26/2010 70 Female 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 10/29/2010 54 Female 177 lb 11/3/2010 Physician Chile
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/18/2009 74 Male 11/12/2010 Other Health Professional Australia
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 51 Female 250 lb 11/16/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 1/26/2010 79 Female 176 lb 11/17/2010
Primary
Secondary
Concomitant
Pituitary Tumour Removal Other Serious 57 Male 11/25/2010 Consumer Germany
Primary
Concomitant
Polyarthritis Hospitalization 10/29/2010 54 Female 177 lb 11/29/2010 Physician Chile
Primary
Secondary
Concomitant
Visual Impairment Other Serious 12/1/2009 58 Male 245 lb 11/28/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/26/2010 57 Female 231 lb 11/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2010 47 Female 187 lb 12/3/2010 Other Health Professional Netherlands
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 200 lb 12/1/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2010 57 Female 12/7/2010 Consumer Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious Female 12/15/2010 Pharmacist Iceland
Primary
Concomitant
Interacting
Pneumonia 12/18/2009 12/16/2010 Consumer United States
Primary
Concomitant
Bronchitis 12/26/2009 12/16/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2010 68 Female 240 lb 12/29/2010 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization Female 1/4/2011 Other Health Professional Iceland
Primary
Concomitant
Interacting
Toxicity To Various Agents Death 56 Female 1/5/2011 Physician United States
Primary
Secondary
Gastrooesophageal Reflux Disease Hospitalization 1/1/2010 Female 1/18/2011 Consumer United States
Primary
Concomitant
Gout Hospitalization 1/1/2010 Female 1/21/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission 1/1/2011 74 Female 137 lb 1/24/2011 Consumer United States
Primary
Concomitant