Metformin combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swollen Tongue Other Serious 12/22/2005 76 Male 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 6/1/2004 55 Male 1/10/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 1/17/2006 Physician United States
Primary
Concomitant
Overdose Hospitalization 1/1/2004 53 Female 220 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 9/22/2003 87 Female 95 lb 1/23/2006 Physician United States
Primary
Concomitant
Insulin Resistance Hospitalization 12/29/2005 35 Female 281 lb 1/27/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 6/25/2005 Male 225 lb 11/4/2005 Pharmacist United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 2/21/2006 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 1/1/2003 75 Female 201 lb 2/23/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/22/2006 Physician United States
Primary
Concomitant
Weight Decreased 8/1/2005 51 Male 210 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2005 63 Male 310 lb 1/20/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 53 Female 220 lb 3/24/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/29/2006 Physician United States
Primary
Concomitant
Hypoglycaemia 10/13/2005 64 Male 267 lb 1/20/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 160 lb 3/31/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 11/10/2005 78 Female 204 lb 1/20/2006 Consumer United States
Primary
Concomitant
Psoriasis Disability 1/1/2006 Female 4/7/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/3/2005 46 Female 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting 12/8/2005 74 Female 172 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2005 51 Male 252 lb 1/20/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia 12/12/2005 57 Male 315 lb 1/20/2006 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/30/2003 66 Female 238 lb 4/13/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Disability 4/15/2002 Female 4/19/2006 Physician United States
Primary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2001 53 Female 185 lb 4/13/2006 United States
Primary
Concomitant
Hallucination, Visual Other Serious 4/20/2006 87 Male 4/24/2006 Consumer United States
Primary
Concomitant
Victim Of Crime Other Serious 1/1/2004 53 Female 220 lb 4/24/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/2/2004 63 Male 231 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Confusional State 11/15/2005 81 Male 1/25/2006 Consumer United States
Primary
Concomitant
Skin Exfoliation Disability 1/1/2004 Female 4/27/2006 Physician United States
Primary
Concomitant
Vascular Occlusion Hospitalization 2/1/2004 63 Male 243 lb 4/28/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 4/12/2006 71 Female 164 lb 4/24/2006 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 64 Male 4/19/2006 Consumer United States
Primary
Secondary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/9/2006 Physician United States
Primary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2001 53 Female 185 lb 5/8/2006 Physician United States
Primary
Concomitant
Vitamin B12 Decreased Other Serious 53 Female 185 lb 5/19/2006 Physician United States
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2006 63 Male 226 lb 5/30/2006 United States
Primary
Concomitant
Weight Increased Other Serious 7/11/2005 Male 160 lb 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 3/22/2006 Male 192 lb 6/5/2006 Consumer United States
Primary
Concomitant
Road Traffic Accident Other Serious 1/1/1995 49 Male 200 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Condition Aggravated 2/1/2006 57 Male 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 7/14/2005 49 Male 248 lb 4/17/2006 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 3/8/2006 53 Female 6/23/2006 Other Health Professional United States
Primary
Concomitant
Blister 3/15/2006 53 Male 350 lb 4/17/2006 Consumer United States
Primary
Concomitant
Myopathy Other Serious 5/8/2006 61 Female 289 lb 7/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity 3/7/2006 39 Male 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 3/14/2006 51 Female 167 lb 4/17/2006 Consumer United States
Primary
Concomitant
Hallucination, Visual Other Serious 4/20/2006 87 Male 7/18/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/13/2006 67 Male 245 lb 7/7/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/28/2006 67 Male 190 lb 5/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2005 55 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Male 7/21/2006 Consumer United States
Primary
Concomitant
Joint Swelling 4/1/2005 64 Female 7/21/2006 Consumer United States
Primary
Concomitant
Rash 12/21/2005 60 Female 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 12/1/2005 73 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/1/2005 68 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2006 72 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 1/1/2005 62 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 69 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased 60 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 59 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 54 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 3/1/2006 47 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/11/2005 Male 160 lb 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/28/2006 67 Male 190 lb 5/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/6/2006 60 Male 180 lb 8/1/2006 United States
Primary
Concomitant
Dyspnoea Hospitalization 6/30/2006 79 Male 167 lb 7/31/2006 Other Health Professional United States
Primary
Concomitant
Marital Problem Other Serious 48 Male 195 lb 8/9/2006 United States
Primary
Concomitant
Thrombosis Hospitalization 8/14/2006 71 Male 8/17/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 7/1/2006 71 Male 8/21/2006 Consumer United States
Primary
Concomitant
Neuropathy Hospitalization 1/1/2006 77 Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess 4/11/2006 70 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 5/1/2006 73 Male 198 lb 8/28/2006 Consumer United States
Primary
Concomitant
Cardiac Disorder Hospitalization 54 Female 115 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/4/2006 59 Female 9/5/2006 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2005 62 Male 200 lb 9/22/2006 Physician United States
Primary
Concomitant
Chromaturia 4/1/2006 67 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Anterior Chamber Inflammation Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 7/7/2006 68 Male 176 lb 11/16/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 9/1/2006 Male 211 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Other Serious 4/1/2006 Female 11/21/2006 United States
Primary
Concomitant
Prostate Examination Abnormal Hospitalization 8/28/2006 62 Male 11/8/2006 Consumer United States
Primary
Concomitant
Nightmare Other Serious 11/1/2006 64 Male 11/22/2006 Consumer United States
Primary
Concomitant
Blood Pressure Inadequately Controlled Other Serious 10/23/2006 46 Male 225 lb 12/2/2006 Consumer United States
Primary
Secondary
Concomitant
Throat Irritation 1/1/2001 54 Female 12/8/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/1/2006 Male 160 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Myalgia Hospitalization 12/16/2006 65 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 55 Female 1/18/2007 Consumer United States
Primary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 1/18/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/1/2006 65 Male 172 lb 1/26/2007 Physician United States
Primary
Concomitant
Weight Decreased 7/12/2006 77 Male 160 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 69 Male 192 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/13/2006 54 Female 220 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2006 57 Female 275 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2006 85 Female 180 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pneumonia Death 11/5/2006 50 Female 165 lb 3/19/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 3/18/2007 79 Male 141 lb 3/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dermatomyositis Other Serious 9/1/2006 68 Female 120 lb 11/28/2006 Physician United States
Primary
Concomitant
Myasthenia Gravis Other Serious 10/17/2006 71 Male 182 lb 4/11/2007 United States
Primary
Secondary
Concomitant
Weight Decreased 8/1/2006 62 Female 185 lb 1/12/2007 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal 1/1/2006 68 Female 220 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2007 79 Male 130 lb 5/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/18/2007 49 Male 5/3/2007 Physician United States
Primary
Concomitant
Angioedema 12/4/2006 65 Female 5/17/2007 Physician United States
Primary
Concomitant
Head Titubation 12/31/2006 53 Male 261 lb 5/17/2007 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 4/13/2007 55 Male 280 lb 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Disability Male 7/5/2007 Pharmacist United States
Primary
Concomitant
Death Disability 3/1/2007 80 Female 90 lb 7/9/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 8/9/2007 Female 174 lb 8/16/2007 Consumer United States
Primary
Concomitant
Haematochezia 8/11/2007 50 Male 389 lb 8/28/2007 Pharmacist United States
Primary
Concomitant
Hypersensitivity Other Serious 7/28/2007 61 Female 205 lb 9/7/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 125 lb 9/21/2007 Physician United States
Primary
Concomitant
Interacting
Pharmaceutical Product Complaint Other Serious 7/23/2007 81 Male 8/9/2007 Pharmacist United States
Primary
Concomitant
Limb Injury Other Serious 7/23/2007 Male 225 lb 9/24/2007 Physician United States
Primary
Concomitant
Hypotension 5/1/2007 72 Female 8/16/2007 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 2/22/2007 52 Female 317 lb 8/16/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 9/16/2005 Female 9/27/2007 United States
Primary
Concomitant
Hypoglycaemia 60 Female 8/16/2007 United States
Primary
Concomitant
Urticaria Other Serious 4/7/2006 66 Male 300 lb 9/20/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 5/30/2007 Female 133 lb 9/28/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 6/25/2007 Female 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Throat Irritation 1/1/2006 65 Male 184 lb 10/24/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 5/30/2007 Female 133 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 7/1/2007 74 Male 247 lb 12/7/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/28/2007 64 Male 229 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Chromaturia Other Serious 57 Female 201 lb 1/21/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 12/29/2007 60 Male 2/15/2008 United States
Primary
Concomitant
Nausea 11/21/2007 67 Female 2/15/2008 Physician United States
Primary
Concomitant
Hallucination, Visual Other Serious 3/15/2008 56 Female 185 lb 6/4/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 194 lb 6/17/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2007 Female 233 lb 6/13/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 6/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gingival Bleeding Other Serious 2/14/2008 Female 155 lb 6/20/2008 Physician United States
Primary
Concomitant
Malaise Other Serious 4/1/2008 62 Female 160 lb 6/17/2008 United States
Primary
Concomitant
Death Death Male 212 lb 6/21/2008 Other Health Professional United States
Primary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/8/2008 Male 265 lb 6/30/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 5/1/2008 Female 199 lb 6/30/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pallor Hospitalization 5/4/2008 78 Male 7/22/2008 Other Health Professional United States
Primary
Concomitant
Chest Pain 76 Male 7/24/2008 Consumer United States
Primary
Concomitant
Fatigue 61 Female 7/24/2008 Consumer United States
Primary
Concomitant

Drug Data