Metformin combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting 49 Female 2/27/2006 Consumer United States
Primary
Concomitant
Ventricular Dyskinesia Hospitalization 9/1/2001 71 Male 276 lb 3/28/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/1/2006 42 Female 3/21/2006 Physician United States
Primary
Concomitant
Weight Decreased 11/1/2005 57 Female 225 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 4/10/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2001 71 Male 276 lb 5/4/2006 Physician United States
Primary
Concomitant
Yellow Skin 2/13/2006 64 Female 202 lb 3/17/2006 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness 2/24/2006 35 Female 5/5/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/1/2005 60 Female 280 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/28/2006 68 Female 210 lb 4/17/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 58 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 3/1/2006 47 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 10/2/2006 46 Female 10/31/2006 Other Health Professional United States
Primary
Concomitant
Body Temperature Increased Other Serious 2/1/2006 57 Female 221 lb 8/18/2006 United States
Primary
Concomitant
Blood Glucose Increased 58 Male 11/30/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 8/2/2006 57 Male 215 lb 10/16/2006 Consumer United States
Primary
Concomitant
Swollen Tongue Hospitalization 3/1/2007 65 Female 225 lb 3/19/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 8/1/2006 65 Male 270 lb 11/28/2006 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 Female 214 lb 7/5/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 301 lb 1/16/2008 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 6/1/2008 Female 134 lb 7/11/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 6/1/2008 46 Female 231 lb 7/15/2008 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/1/2008 Female 130 lb 7/23/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 280 lb 7/22/2008 Consumer United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 2/1/2008 Female 182 lb 12/16/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2008 64 Male 183 lb 12/29/2008 Physician United States
Primary
Concomitant
Pain Hospitalization 11/1/2007 60 Female 125 lb 1/22/2009 Pharmacist United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 2/1/2008 Female 182 lb 1/26/2009 Consumer United States
Primary
Secondary
Concomitant
Atrioventricular Block Other Serious 2/10/2009 Female 175 lb 2/11/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2008 64 Male 183 lb 2/19/2009 Physician United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 150 lb 3/4/2009 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/23/2001 45 Female 314 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 9/21/1999 26 Female 210 lb 4/13/2009 United States
Primary
Concomitant
Arthralgia 5/12/2009 73 Female 143 lb 6/10/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 Female 165 lb 6/10/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2001 44 Female 269 lb 8/5/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2004 40 Female 314 lb 8/10/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/1995 Female 270 lb 8/20/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 60 Female 125 lb 9/25/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased 55 Female 270 lb 10/2/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 60 Female 125 lb 10/21/2009 Pharmacist United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Adverse Event Female 198 lb 11/5/2009 Lawyer United States
Primary
Concomitant
Vomiting 9/1/2009 Female 195 lb 10/27/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 Female 191 lb 12/31/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 4/22/2005 Female 1/5/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 12/21/2009 Female 151 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Sphincter Of Oddi Dysfunction Other Serious 10/15/2008 Female 226 lb 3/19/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2008 Female 210 lb 3/26/2010 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 12/21/2008 49 Male 385 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious Male 4/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 4/3/2010 55 Female 4/23/2010 Other Health Professional United States
Primary
Concomitant
Stress 7/1/2009 60 Female 167 lb 4/22/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 29 Female 274 lb 6/3/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/23/2001 45 Female 314 lb 6/4/2010 United States
Primary
Secondary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Tinnitus 4/1/2009 63 Female 235 lb 7/13/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 5/1/2007 56 Male 190 lb 7/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased 4/1/2007 60 Female 230 lb 7/13/2010 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 4/1/2008 42 Female 281 lb 7/21/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2003 68 Female 194 lb 7/21/2010 Physician United States
Primary
Concomitant
Paraesthesia Oral 57 Female 6/2/2010 Physician United States
Primary
Concomitant
Macular Degeneration Other Serious 2/1/2010 35 Male 300 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 58 Female 304 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Pruritus 8/1/2009 57 Female 230 lb 8/28/2010 United States
Primary
Concomitant
Sleep Disorder 6/9/2010 37 Female 229 lb 8/29/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 268 lb 8/27/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/1/2002 34 Female 230 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/17/2006 46 Male 260 lb 9/20/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2006 40 Male 324 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 10/30/2007 55 Female 162 lb 9/20/2010 United States
Primary
Concomitant
Epilepsy Other Serious Male 325 lb 9/20/2010 Physician United States
Primary
Concomitant
Glaucoma Other Serious 30 Female 270 lb 9/20/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2003 43 Female 135 lb 9/20/2010 United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2003 45 Female 324 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased 1/31/2003 31 Male 393 lb 9/20/2010 United States
Primary
Concomitant
Wound Other Serious 1/31/2003 31 Male 160 lb 9/21/2010 United States
Primary
Concomitant
Cardiomyopathy Hospitalization 61 Female 279 lb 9/28/2010 Other Health Professional United States
Primary
Concomitant
Self-medication Other Serious 9/15/2010 59 Female 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death 8/13/2010 63 Female 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/3/2010 35 Female 333 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Nystagmus 10/1/2010 49 Female 186 lb 10/14/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious Female 264 lb 11/16/2010 Consumer United States
Primary
Concomitant
Macular Oedema Other Serious 15 Female 11/29/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 58 Female 304 lb 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Effect Decreased Other Serious 1/1/2010 34 Female 155 lb 1/18/2011 Consumer United States
Primary
Concomitant
Bunion Other Serious 3/28/2003 44 Female 256 lb 1/20/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 43 Female 238 lb 1/20/2011 Physician United States
Primary
Concomitant
Pain Of Skin Other Serious 3/2/2010 55 Female 1/28/2011 Physician United States
Primary
Concomitant
Oedema 28 Female 1/29/2011 Consumer United States
Primary
Concomitant
Wound Infection 10/1/2010 62 Female 102 lb 1/30/2011 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis 9/9/2010 59 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Death 12/13/2010 57 Female 2/2/2011 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 34 Female 155 lb 2/7/2011 Consumer United States
Primary
Concomitant
Drug Intolerance 3/1/2010 54 Female 245 lb 2/28/2011 Consumer United States
Primary
Concomitant
Asthma Other Serious 1/1/2002 17 Female 200 lb 3/3/2011 Other Health Professional United States
Primary
Concomitant
Akathisia Other Serious 1/1/1984 32 Female 115 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Aortic Stenosis Death Female 3/22/2011 Physician Canada
Primary
Concomitant
Back Pain 10/1/2010 72 Female 201 lb 4/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2011 59 Male 9/2/2011 Other Health Professional United States
Primary
Concomitant
Retinal Vein Thrombosis Other Serious 53 Female 9/12/2011 Other Health Professional Italy
Primary
Concomitant
Drug Ineffective 1/1/2006 44 Female 240 lb 9/13/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission 50 Female 9/22/2011 United States
Primary
Concomitant
Irritability 41 Female 275 lb 9/22/2011 Consumer United States
Primary
Concomitant
Pain Death 8/1/2005 42 Female 257 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Dermal Cyst 1/1/2001 35 Female 195 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 9/28/2010 Male 9/22/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 10/1/2010 25 Female 230 lb 10/28/2011 Consumer United States
Primary
Concomitant
Vomiting Death 11/1/2007 58 Female 304 lb 11/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Polycystic Ovaries Other Serious 1/1/1999 26 Female 160 lb 2/1/2012 Consumer United States
Primary
Concomitant
Drug Withdrawal Syndrome 1/24/2012 39 Female 160 lb 2/1/2012 Consumer United States
Primary
Concomitant
Irritability 1/24/2012 39 Female 160 lb 2/6/2012 Consumer United States
Primary
Concomitant
Abasia Disability 6/1/2011 42 Female 210 lb 2/15/2012 Other Health Professional United States
Primary
Concomitant
Burning Sensation Disability 6/1/2011 42 Female 210 lb 2/21/2012 Other Health Professional United States
Primary
Concomitant
Vestibular Disorder Disability Male 224 lb 2/23/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Female 180 lb 3/26/2012 Consumer United States
Primary
Concomitant
Insomnia Female 180 lb 4/1/2012 Consumer United States
Primary
Concomitant
Vestibular Disorder Disability Male 224 lb 4/5/2012 Consumer United States
Primary
Concomitant
Drug Screen False Positive 5/4/2011 32 Female 215 lb 4/24/2012 Consumer United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 3/1/2012 54 Female 5/10/2012 Consumer United States
Primary
Concomitant
Pruritus 4/25/2012 Female 5/16/2012 Consumer United States
Primary
Concomitant
Insomnia Other Serious 6/5/2012 Female 6/8/2012 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 1/1/2012 Female 6/8/2012 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 4/5/2010 27 Female 11/7/2012 Us
Primary
Secondary
Concomitant
Ulcer Other Serious 2008 41 Female 311 lb 8/20/2012 Lawyer Us
Primary
Concomitant
Cardiovascular Disorder Male 277 lb 12/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 3/2012 55 Female 9/14/2012 Consumer Us
Primary
Concomitant
Perineal Injury Other Serious Female 10/19/2012 Consumer Us
Primary
Secondary
Concomitant
Speech Disorder Congenital Anomaly Female 9/20/2012 Consumer Us
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 311 lb 9/14/2012 Other Health Professional Us
Primary
Concomitant
Tremor Hospitalization 7/2008 36 Female 143 lb 12/27/2012 Consumer Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/30/2012 9/28/2012 Physician Us
Primary
Secondary
Concomitant
Speech Disorder Other Serious Female 6 lb 10/3/2012 Consumer Us
Primary
Secondary
Concomitant
Perineal Injury Other Serious 29 Female 10/25/2012 Consumer Us
Primary
Secondary
Concomitant
Weight Increased 2008 35 Female 148 lb 9/27/2012 Consumer Us
Primary
Concomitant
Migraine 11/2011 Female 230 lb 10/25/2012 Consumer Country Not Specified
Primary
Concomitant
Urinary Tract Infection Female 135 lb 10/25/2012 Physician Us
Primary
Concomitant
Migraine Male 205 lb 10/30/2012 Physician Us
Primary
Concomitant
Weight Increased Other Serious 2005 Female 10/30/2012 Physician Us
Primary
Concomitant

Drug Data