Metformin combined with Temazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nightmare Other Serious 12/19/2005 Male 258 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/26/2006 78 Female 178 lb 5/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 12/22/2004 57 Male 210 lb 5/26/2006 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 59 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/12/2006 70 Male 6/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia 75 Female 7/21/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Yellow Skin Other Serious 76 Male 225 lb 7/31/2006 Pharmacist Netherlands
Primary
Concomitant
Tooth Abscess 4/11/2006 70 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 5/1/2006 73 Male 198 lb 8/28/2006 Consumer United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 80 Female 10/5/2006 Netherlands
Primary
Secondary
Concomitant
Anterior Chamber Inflammation Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Poisoning Death 42 11/6/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 2/11/2004 46 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 67 Female 158 lb 11/22/2006 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Adverse Drug Reaction Death 42 11/28/2006 Physician United States
Primary
Secondary
Myalgia Hospitalization 12/16/2006 65 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 12/1/2006 65 Male 172 lb 1/26/2007 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/20/2007 64 Male 163 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 5/31/2006 Male 251 lb 6/28/2007 Consumer United States
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 10/13/2007 65 Female 11/8/2007 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/1/2007 65 Female 165 lb 1/28/2008 Physician United States
Primary
Concomitant
Death Death 3/15/2008 61 Female 3/25/2008 Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2005 Female 200 lb 3/24/2008 Consumer United States
Primary
Concomitant
Death Death 3/15/2008 61 Female 3/26/2008 Physician Netherlands
Primary
Secondary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 7/11/2002 45 Female 6/20/2008 Physician United Kingdom
Primary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Discomfort Hospitalization 12/23/2006 Male 206 lb 7/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Haemorrhage Hospitalization 3/1/2008 Female 128 lb 7/16/2008 Physician United States
Primary
Concomitant
Fatigue 1/1/1994 Female 174 lb 8/22/2008 Consumer United States
Primary
Concomitant
Wound Haemorrhage Hospitalization 3/1/2008 Female 128 lb 10/24/2008 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2006 Female 1/13/2009 Consumer
Primary
Concomitant
Renal Impairment Hospitalization 7/20/2006 45 Male 241 lb 1/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 2/19/2009 Physician United States
Primary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 11/19/2001 42 Male 210 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 4/10/2009 Physician United States
Primary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2008 Male 146 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 6/4/2009 Physician United States
Primary
Concomitant
Rash Pruritic Death 4/9/2008 Male 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 6/8/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 Female 245 lb 7/31/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 46 Female 8/6/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 66 Male 7/31/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/10/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/28/2008 Male 8/19/2009 Physician United States
Primary
Concomitant
Skin Burning Sensation Female 8/21/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 Female 245 lb 9/15/2009 Consumer United States
Primary
Concomitant
Product Quality Issue 7/1/2008 65 Female 10/7/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/6/2009 Male 195 lb 10/7/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 42 Female 10/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Vasculitic Rash Other Serious 8/24/2009 67 10/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/6/2009 Male 195 lb 11/14/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 42 Female 12/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 42 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 42 Female 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Other Serious 1/1/2007 59 Male 199 lb 12/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/23/2009 1/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Intervertebral Disc Disorder Other Serious 10/1/2009 Female 212 lb 1/5/2010 Consumer United States
Primary
Concomitant
Disease Progression Death 5/1/2009 Female 1/5/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 42 Female 1/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Failure Congestive Death Male 191 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 Female 174 lb 3/11/2010 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 2/1/2010 68 Female 214 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Wound Dehiscence Hospitalization 9/11/2009 65 Male 309 lb 5/6/2010 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/1/2007 60 Female 163 lb 6/16/2010 Consumer United States
Primary
Concomitant
Overdose Hospitalization 6/16/2010 24 Male 190 lb 8/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Male 215 lb 8/27/2010 United States
Primary
Concomitant
Pruritus Male 300 lb 8/29/2010 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 2/22/2009 37 Male 266 lb 9/16/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 57 Female 245 lb 9/16/2010 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 8/31/2005 36 Male 114 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased Other Serious 3/23/2001 53 Male 219 lb 9/21/2010 United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 7/19/2010 66 Male 309 lb 9/24/2010 Physician United States
Primary
Concomitant
Rash Erythematous Other Serious 9/13/2010 60 Female 220 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 9/30/2010 Other Health Professional United States
Primary
Concomitant
Drug Administration Error Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 6/16/2010 24 Male 180 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 6/6/2005 56 Female 150 lb 10/14/2010 Physician United Kingdom
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 203 lb 10/6/2010 Other Health Professional
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 10/26/2010 Other Health Professional United States
Primary
Concomitant
Haematuria Hospitalization 7/18/2010 63 Male 11/5/2010 Physician Netherlands
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2009 30 Female 216 lb 11/8/2010 Physician United States
Primary
Concomitant
Cytogenetic Abnormality Congenital Anomaly 1/1/2009 11/8/2010 Physician United States
Primary
Concomitant
Turner's Syndrome Congenital Anomaly 1/1/2008 11/8/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2008 29 Female 216 lb 11/8/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 11/8/2010 Other Health Professional United States
Primary
Concomitant
Enuresis Other Serious 4/1/2008 47 Female 200 lb 11/8/2010 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 10/29/2010 70 Male 169 lb 11/11/2010 Physician Canada
Primary
Concomitant
Atrial Fibrillation 11/1/2008 73 Male 203 lb 11/24/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Tendonitis Other Serious Male 11/30/2010 Other Health Professional Netherlands
Primary
Concomitant
Tendonitis Other Serious Male 11/30/2010 Other Health Professional Netherlands
Primary
Concomitant
Tendonitis Other Serious 80 Male 12/7/2010 Other Health Professional Netherlands
Primary
Concomitant
Ventricular Fibrillation Hospitalization 46 Female 12/14/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 57 Female 245 lb 9/15/2009 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 11/16/2010 71 Female 143 lb 12/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Death 63 Female 265 lb 12/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Abnormal Other Serious 12/28/2010 58 Female 1/11/2011 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2002 34 Female 205 lb 1/20/2011 Consumer United States
Primary
Concomitant
Eye Infection 8/13/2010 68 Female 205 lb 1/29/2011 Consumer United States
Primary
Concomitant
Constipation 12/10/2010 71 Female 265 lb 2/3/2011 Consumer United States
Primary
Concomitant
Blood Triglycerides Increased Other Serious 4/1/2008 47 Female 200 lb 2/22/2011 Physician United States
Primary
Concomitant
Blood Urine Present Other Serious 5/1/2008 47 Female 200 lb 2/25/2011 Physician United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 2/15/2011 59 Female 220 lb 3/8/2011 Other Health Professional Canada
Primary
Concomitant
Anaemia Other Serious 12/1/2010 36 Female 174 lb 3/9/2011 Consumer United States
Primary
Secondary
Concomitant
Furuncle Other Serious 12/1/2010 36 Female 174 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 12/1/2010 36 Female 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Bacterial Infection Other Serious 12/1/2010 36 Female 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 59 Male 183 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 11/2/2010 61 Male 4/18/2011 Physician Netherlands
Primary
Concomitant
Nausea Hospitalization 11/2/2010 61 Male 4/25/2011 Other Health Professional Netherlands
Primary
Concomitant
Anxiety Hospitalization 7/20/2002 64 Male 172 lb 4/28/2011 Lawyer United States
Primary
Concomitant
Nervousness Hospitalization 11/16/2005 56 Male 255 lb 7/25/2011 Lawyer United States
Primary
Concomitant
Respiratory Arrest Death 7/9/2011 86 Male 132 lb 7/25/2011 Physician United States
Primary
Concomitant
Back Pain Other Serious 10/1/2003 70 Male 8/31/2011 Physician United States
Primary
Secondary
Concomitant
Accidental Overdose Death 48 Female 247 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Malaise 1/1/2006 43 Male 180 lb 9/22/2011 United States
Primary
Concomitant
Leukaemia Other Serious 7/6/2010 49 Female 9/22/2011 Physician United Kingdom
Primary
Concomitant
Pain In Extremity 12/3/2006 38 Female 215 lb 9/22/2011 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 64 Male 10/4/2011 Pharmacist Australia
Primary
Concomitant
Angina Unstable Hospitalization 68 Male 11/7/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 68 Male 11/9/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Pain Hospitalization 2/1/2011 47 Female 11/14/2011 Consumer Switzerland
Primary
Concomitant
Psychotic Behaviour Death 8/29/2010 65 Male 12/8/2011 Physician United Kingdom
Primary
Concomitant
Compulsive Sexual Behaviour Other Serious 11/21/2011 77 Male 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 7/6/2010 49 Female 3/7/2012 Physician United Kingdom
Primary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 3/14/2012 Other Health Professional United Kingdom
Primary
Concomitant
Bone Pain Hospitalization 10/1/2003 70 Male 3/14/2012 Physician United States
Primary
Secondary
Concomitant
Erythema Hospitalization Male 3/14/2012 Consumer United States
Primary
Concomitant
Back Disorder Other Serious 1/1/2011 51 Female 193 lb 7/19/2012 Consumer United States
Primary
Concomitant
Back Disorder Other Serious 1/1/2011 52 Female 193 lb 8/21/2012 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 8/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Toxicity To Various Agents Death 12/1/2008 38 Male 10/1/2012 Physician Us
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization Female 135 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Sepsis Hospitalization 7/28/2011 74 Male 190 lb 10/2/2012 Physician Au
Primary
Concomitant
Pneumonia Hospitalization 12/7/2011 66 Female 9/18/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Hypoacusis Other Serious 2009 63 Female 198 lb 9/12/2012 Consumer Us
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 2010 Female 149 lb 9/28/2012 Consumer Pr
Primary
Secondary
Concomitant

Drug Data