Metformin combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 1/17/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 4/27/2000 60 Female 209 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 12/1/2005 Female 164 lb 1/31/2006 Other Health Professional Canada
Primary
Concomitant
Insulin Resistance Hospitalization 12/29/2005 35 Female 281 lb 1/27/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 79 Female 2/7/2006 Other Health Professional Canada
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 2/21/2006 Physician United States
Primary
Concomitant
Urticaria 11/15/2005 45 Male 2/27/2006 Consumer United States
Primary
Concomitant
Photosensitivity Reaction 6/1/2005 48 Male 267 lb 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 1/1/2006 49 Male 209 lb 2/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 4/16/2004 81 Female 141 lb 3/10/2006 Lawyer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 55 Female 3/13/2006 Consumer United States
Primary
Concomitant
Injection Site Irritation 12/7/2005 54 Female 156 lb 1/20/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 6/1/2005 63 Female 152 lb 1/20/2006 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/22/2006 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2005 63 Male 310 lb 1/20/2006 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/2/2002 81 Female 141 lb 3/27/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/1/2006 42 Female 3/21/2006 Physician United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/1/2006 56 Male 209 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/29/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased 11/22/2005 55 Male 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/27/2000 60 Female 209 lb 4/3/2006 Physician United States
Primary
Concomitant
Vomiting 10/21/2005 54 Female 156 lb 1/20/2006 Consumer United States
Primary
Concomitant
Hunger 9/6/2005 59 Female 312 lb 1/20/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 10/1/2005 70 Female 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 2/13/2006 Male 4/5/2006 Physician Canada
Primary
Concomitant
Suicidal Ideation Hospitalization 3/6/2006 42 Female 220 lb 3/24/2006 Physician United States
Primary
Concomitant
Stomach Discomfort 10/23/2005 51 Female 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 10/24/2005 55 Male 174 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 9/1/2005 70 Female 200 lb 1/20/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2005 83 Female 3/30/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
Headache 12/11/2005 67 Female 290 lb 1/20/2006 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2006 83 Female 4/4/2006 Pharmacist Canada
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/30/2003 66 Female 238 lb 4/13/2006 Physician United States
Primary
Concomitant
Overdose Other Serious 9/25/2005 Female 1/10/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Pain In Extremity Disability 1/1/2006 53 Female 226 lb 4/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 65 Male 5/3/2006 Physician Canada
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 4/12/2006 71 Female 164 lb 4/24/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 12/15/2003 79 Female 160 lb 4/27/2006 Canada
Primary
Concomitant
Emphysema 7/1/2005 67 Female 2/21/2006 United States
Primary
Concomitant
Weight Increased 1/7/2006 65 Male 230 lb 2/20/2006 United States
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2002 71 Male 220 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Oedema Other Serious 3/13/2006 80 Male 162 lb 5/17/2006 Physician Canada
Primary
Concomitant
Tremor Hospitalization 1/1/2005 85 Female 5/10/2006 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 1/1/2005 Male 5/24/2006 Consumer United States
Primary
Concomitant
Somnolence 11/8/2005 54 Female 170 lb 3/23/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 5/8/2006 67 Female 136 lb 5/25/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 70 Female 271 lb 6/8/2006 Physician Canada
Primary
Concomitant
Yellow Skin 2/13/2006 64 Female 202 lb 3/17/2006 Consumer United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 86 Female 125 lb 6/13/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 6/27/2006 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 4/21/2005 50 Female 299 lb 5/18/2006 Physician United States
Primary
Concomitant
Injection Site Urticaria 3/2/2006 56 Female 227 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/6/2006 65 Male 230 lb 4/17/2006 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort 10/23/2005 51 Female 195 lb 4/17/2006 Consumer United States
Primary
Concomitant
Injection Site Urticaria 1/1/2005 67 Female 4/17/2006 Physician United States
Primary
Concomitant
Weight Increased 1/1/2006 49 Female 244 lb 4/17/2006 Consumer United States
Primary
Concomitant
Dry Mouth 2/27/2006 67 Female 4/17/2006 Consumer United States
Primary
Concomitant
Injection Site Urticaria 3/27/2006 49 Female 225 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 2/6/2006 58 Female 239 lb 4/17/2006 Consumer United States
Primary
Concomitant
Procedural Pain 2/22/2006 53 Female 226 lb 4/17/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/19/2004 77 Male 195 lb 6/27/2006 United States
Primary
Concomitant
Injection Site Haemorrhage 2/26/2006 52 Female 240 lb 4/17/2006 Consumer United States
Primary
Concomitant
Rash 12/25/2005 41 Female 4/17/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Abnormal 12/1/2005 54 Female 190 lb 4/17/2006 Consumer United States
Primary
Concomitant
Medication Error 2/18/2006 59 Female 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 47 Female 265 lb 4/17/2006 Consumer United States
Primary
Concomitant
Sneezing 3/6/2006 38 Female 197 lb 4/17/2006 Consumer United States
Primary
Concomitant
Somnolence 2/9/2006 66 Female 186 lb 4/17/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 6/20/2006 50 Male 7/7/2006 Physician Canada
Primary
Concomitant
Protein Urine Present Other Serious 7/4/2006 56 Female 190 lb 7/14/2006 United States
Primary
Secondary
Concomitant
Blood Glucose Increased 6/1/2005 66 Female 7/21/2006 Consumer United States
Primary
Concomitant
Headache 8/10/2005 39 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2005 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Fatigue 9/1/2005 80 Female 7/21/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious Male 7/21/2006 Consumer United States
Primary
Concomitant
Joint Swelling 4/1/2005 64 Female 7/21/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Male 7/21/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 2/9/2006 77 Female 7/21/2006 Consumer United States
Primary
Concomitant
Headache 64 Female 7/21/2006 Consumer United States
Primary
Concomitant
Malaise 1/1/2005 66 Female 171 lb 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Female 7/21/2006 Consumer United States
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/1/2005 Female 212 lb 7/26/2006 Physician United States
Primary
Concomitant
Lipoma Of Breast Other Serious 4/1/2006 55 Female 128 lb 8/3/2006 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/7/2006 88 Female 8/10/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 5/23/2004 51 Female 8/7/2006 Other Health Professional Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/7/2006 88 Female 8/18/2006 Physician Canada
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 8/3/2006 53 Female 8/21/2006 Consumer Canada
Primary
Concomitant
Weight Decreased 7/4/2005 38 Female 278 lb 7/19/2006 United States
Primary
Concomitant
Dyspnoea Hospitalization 9/1/2006 Female 179 lb 9/22/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation Death 11/1/2004 57 Female 10/6/2006 Consumer United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/1/2006 60 Female 252 lb 10/31/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 9/28/2006 72 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 11/2/2006 Physician United States
Primary
Concomitant
Eructation Other Serious 10/4/2006 74 Female 180 lb 11/15/2006 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Intestinal Obstruction Other Serious 4/1/2006 Female 11/21/2006 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/7/2006 88 Female 12/14/2006 Physician Canada
Primary
Secondary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 55 Female 1/2/2007 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 9/28/2006 72 Female 141 lb 1/16/2007 Physician United States
Primary
Secondary
Concomitant
Pubic Rami Fracture Other Serious 8/1/2006 66 Male 206 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/5/2006 Female 1/18/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 3/23/2006 65 Female 258 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 80 Male 200 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 7/1/2006 46 Female 180 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2006 70 Male 205 lb 10/16/2006 Consumer United States
Primary
Concomitant
Vomiting 8/16/2006 36 Female 10/16/2006 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 2/1/2007 58 Female 183 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 11/5/2006 Female 3/12/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious Female 200 lb 3/21/2007 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 7/1/2006 76 Male 195 lb 11/28/2006 United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 10/6/2006 68 Female 4/2/2007 Consumer United States
Primary
Concomitant
Sciatica 1/1/2007 58 Female 150 lb 5/17/2007 Physician United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2007 47 Female 296 lb 6/12/2007 Physician United States
Primary
Concomitant
Weight Decreased 12/15/2006 44 Female 163 lb 4/10/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 3/16/2007 55 Female 6/22/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 6/22/2007 Female 186 lb 6/25/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/13/2007 79 Female 106 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 1/1/2007 73 Male 9/6/2007 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 7/20/2007 57 Female 247 lb 9/11/2007 Physician United States
Primary
Concomitant
Hemianopia Homonymous Other Serious 4/17/2007 Female 9/11/2007 Physician United States
Primary
Concomitant
Renal Disorder 3/1/2007 70 Female 8/16/2007 Physician United States
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 9/28/2007 Consumer Brazil
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 9/28/2007 Consumer Brazil
Primary
Concomitant
Sensation Of Foreign Body 1/5/2007 30 Female 260 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pain In Extremity 6/25/2007 Female 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 8/17/2007 Female 10/9/2007 Physician United States
Primary
Concomitant
Performance Status Decreased Other Serious 1/6/2007 56 Male 165 lb 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 6/22/2007 66 Female 187 lb 10/18/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia 10/15/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Required Intervention 10/10/2007 59 Female 201 lb 10/18/2007 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 10/25/2007 Consumer Brazil
Primary
Concomitant
Pharmaceutical Product Complaint 10/19/2006 66 Female 10/25/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 12/1/2004 68 Female 137 lb 10/25/2007 Consumer United States
Primary
Concomitant
Varicella 1/1/2006 59 Female 10/26/2007 Consumer United States
Primary
Concomitant
Hallucination, Auditory Other Serious 9/30/2007 67 Female 215 lb 10/24/2007 United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/1/2000 46 Female 315 lb 11/9/2007 Other Health Professional United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/14/2000 46 Female 315 lb 12/21/2007 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/1/2007 17 Male 166 lb 12/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 Female 1/1/2008 Physician United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/14/2000 46 Female 315 lb 2/21/2008 Other Health Professional United States
Primary
Concomitant
Device Occlusion Hospitalization 9/17/2007 61 Female 3/3/2008 Consumer United States
Primary
Concomitant

Drug Data