Metformin combined with Sutent

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Anaphylactic Reaction Life Threatening 1/19/2006 60 Male 260 lb 2/17/2006 Other Health Professional United States
Primary
Concomitant
Troponin Increased Other Serious 2/3/2006 68 Male 172 lb 3/15/2006 Physician Italy
Primary
Concomitant
Stress Hospitalization 1/11/2006 68 Female 153 lb 3/20/2006 Other Health Professional Canada
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 5/6/2006 61 Male 148 lb 5/19/2006 Other Health Professional Brazil
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 5/6/2006 61 Male 148 lb 5/31/2006 Physician Brazil
Primary
Concomitant
Vomiting Hospitalization 4/12/2006 70 Male 6/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 6/13/2006 Other Health Professional Brazil
Primary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 6/22/2006 Physician Hong Kong
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 6/26/2006 Physician Brazil
Primary
Concomitant
Somnolence Life Threatening 2/24/2006 68 Male 153 lb 6/30/2006 Physician France
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 7/11/2006 Physician Brazil
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 7/11/2006 Physician Brazil
Primary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 7/14/2006 Physician Hong Kong
Primary
Concomitant
Syncope Hospitalization 7/26/2006 67 Male 169 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 7/27/2006 47 Male 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/26/2006 67 Male 169 lb 9/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 12/18/2005 74 Male 206 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/6/2006 61 Male 148 lb 11/16/2006 Physician Brazil
Primary
Concomitant
Surgical Procedure Repeated Other Serious 10/22/2006 66 Male 183 lb 11/22/2006 Physician France
Primary
Concomitant
Pyrexia Other Serious 10/22/2006 Male 183 lb 1/17/2007 Physician France
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 10/22/2006 Male 183 lb 2/12/2007 Physician France
Primary
Concomitant
Cerebral Haemorrhage Other Serious 8/26/2007 Male 200 lb 9/7/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia 10/15/2007 Other Health Professional United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/17/2008 Male 304 lb 10/14/2008 United States
Primary
Concomitant
Vomiting Hospitalization 10/2/2008 2/4/2009 Physician France
Primary
Concomitant
Disorientation Hospitalization 9/1/2009 Male 159 lb 12/29/2009 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious Female 2/19/2010 Consumer United States
Primary
Concomitant
Psoriasis Other Serious 1/1/2009 65 Male 265 lb 4/9/2010 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 6/1/2009 65 Female 188 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 5/7/2010 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/1/2010 70 Male 181 lb 5/18/2010 Physician United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 6/22/2010 Consumer United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 7/8/2010 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 6/1/2009 65 Female 188 lb 7/22/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 70 Male 177 lb 8/10/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Vulvovaginal Pruritus 4/1/2009 78 Female 291 lb 9/14/2010 Consumer United States
Primary
Concomitant
Periorbital Oedema Other Serious 12/1/2009 72 Male 9/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 7/1/2010 83 Female 165 lb 9/30/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 70 Male 178 lb 10/6/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Lethargy Other Serious 7/1/2010 83 Female 165 lb 11/5/2010 Physician United States
Primary
Concomitant
Sepsis Life Threatening 11/7/2010 68 Male 11/15/2010 Physician Netherlands
Primary
Concomitant
Dysstasia Hospitalization 11/1/2010 81 Male 130 lb 11/22/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Metastases To Lymph Nodes Other Serious 10/1/2010 66 Male 12/9/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2010 Female 12/29/2010 Consumer India
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Pericardial Effusion Hospitalization Male 280 lb 1/19/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 11/13/2010 49 Male 164 lb 1/24/2011 Pharmacist Canada
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 66 Male 198 lb 1/26/2011 Physician Hungary
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Oropharyngeal Plaque Other Serious 1/29/2011 58 Male 2/7/2011 Physician Colombia
Primary
Concomitant
Dyspnoea 3/7/2011 85 Male 3/14/2011 Other Health Professional United States
Primary
Concomitant
Pericardial Effusion Hospitalization Male 280 lb 3/23/2011 Physician United States
Primary
Concomitant
Death Death 3/1/2011 85 Male 3/23/2011 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2010 62 Male 4/4/2011 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 11/7/2010 68 Male 4/5/2011 Physician Netherlands
Primary
Concomitant
Colitis Hospitalization 3/28/2011 77 Male 174 lb 4/14/2011 Physician France
Primary
Concomitant
Hypotension Other Serious Male 260 lb 4/29/2011 Consumer United States
Primary
Concomitant
Colitis Hospitalization 3/27/2011 77 Male 172 lb 5/5/2011 Physician France
Primary
Concomitant
Death Death Male 5/6/2011 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Other Serious 4/1/2011 68 Male 192 lb 5/6/2011 Consumer United States
Primary
Concomitant
Hypotension Other Serious Male 260 lb 5/9/2011 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 5/3/2011 59 Male 152 lb 5/12/2011 Physician Netherlands
Primary
Concomitant
Headache 5/8/2011 59 Male 180 lb 5/13/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 10/8/2008 6/22/2011 Physician Italy
Primary
Concomitant
Hypotension Other Serious Male 260 lb 7/4/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 10/8/2008 7/5/2011 Physician Italy
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 10/8/2008 7/7/2011 Physician Italy
Primary
Concomitant
Haematemesis Other Serious 7/6/2011 61 Male 131 lb 7/13/2011 Pharmacist United States
Primary
Concomitant
Dyspnoea 4/18/2011 63 Male 269 lb 7/14/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/11/2011 55 Female 190 lb 7/20/2011 Consumer United States
Primary
Concomitant
Fall Other Serious 7/27/2011 58 Female 195 lb 8/18/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/11/2011 55 Female 181 lb 8/25/2011 Consumer United States
Primary
Concomitant
Lacrimation Increased 4/18/2011 63 Male 269 lb 8/29/2011 Consumer United States
Primary
Concomitant
Decreased Appetite 7/18/2011 73 Female 119 lb 8/29/2011 Consumer United States
Primary
Concomitant
Blood Thyroid Stimulating Hormone Decreased Other Serious 12/10/2010 50 Female 146 lb 9/7/2011 Pharmacist Brazil
Primary
Concomitant
Oral Pain 9/6/2011 60 Male 9/9/2011 Consumer United States
Primary
Concomitant
Acute Disseminated Encephalomyelitis Hospitalization 8/14/2011 70 Female 115 lb 9/13/2011 Physician Denmark
Primary
Concomitant
Musculoskeletal Chest Pain 9/2/2011 60 Male 220 lb 9/20/2011 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 64 Male 10/4/2011 Pharmacist Australia
Primary
Concomitant
Hair Colour Changes 8/5/2011 55 Male 291 lb 10/12/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/7/2011 66 Male 198 lb 10/11/2011 Physician Hungary
Primary
Concomitant
Contusion 9/1/2011 61 Male 200 lb 11/7/2011 Consumer United States
Primary
Concomitant
Somnolence Male 333 lb 11/7/2011 Consumer United States
Primary
Concomitant
Encephalitis Hospitalization 8/14/2011 70 Female 115 lb 11/23/2011 Physician Denmark
Primary
Concomitant
Blood Pressure Increased Male 11/23/2011 Consumer United States
Primary
Concomitant
Diarrhoea Male 333 lb 11/30/2011 Consumer United States
Primary
Concomitant
Lung Infection Hospitalization 6/1/2011 79 Female 128 lb 2/15/2012 Pharmacist Brazil
Primary
Concomitant
Vomiting Other Serious 2/1/2012 81 Male 137 lb 3/7/2012 Consumer Brazil
Primary
Concomitant
Vascular Calcification 1/1/2012 66 Male 180 lb 3/14/2012 Consumer United States
Primary
Concomitant
Tongue Disorder Other Serious 2/1/2012 81 Male 137 lb 3/15/2012 Consumer Brazil
Primary
Concomitant
Diarrhoea 3/22/2012 82 Male 208 lb 3/28/2012 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased 1/1/2012 66 Male 180 lb 3/29/2012 Consumer United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 2/17/2012 67 Male 4/2/2012 Physician Netherlands
Primary
Concomitant
Pain Other Serious 1/1/2012 81 Male 208 lb 4/12/2012 Consumer United States
Primary
Concomitant
Somnolence Male 218 lb 4/21/2012 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 1/1/2012 81 Male 208 lb 4/26/2012 Consumer United States
Primary
Concomitant
Vascular Calcification 1/1/2012 66 Male 180 lb 5/8/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 1/1/2012 69 Male 218 lb 5/8/2012 Consumer United States
Primary
Secondary
Concomitant
Penile Haemorrhage Other Serious 1/1/2012 81 Male 208 lb 5/16/2012 Physician United States
Primary
Concomitant
Testicular Pain Other Serious 12/1/2011 61 Male 195 lb 5/22/2012 Physician United States
Primary
Concomitant
Fatigue Other Serious 3/1/2012 61 Male 196 lb 5/22/2012 Consumer United States
Primary
Concomitant
Limb Discomfort Female 5/23/2012 Other Health Professional United States
Primary
Concomitant
Somnolence 1/1/2012 69 Male 218 lb 5/30/2012 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 67 Male 6/7/2012 Pharmacist Brazil
Primary
Concomitant
Constipation 1/1/2012 69 Male 225 lb 6/11/2012 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 67 Male 7/5/2012 Pharmacist Brazil
Primary
Concomitant
Nausea 1/1/2012 66 Male 265 lb 7/16/2012 Consumer United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 7/29/2012 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 6/1/2012 63 Male 305 lb 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Somnolence 1/1/2012 69 Male 227 lb 8/8/2012 Consumer United States
Primary
Secondary
Concomitant
Lymphadenopathy Other Serious 12/1/2011 61 Male 195 lb 8/9/2012 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 57 Male 8/9/2012 Physician United States
Primary
Concomitant
Fatigue Female 8/22/2012 Consumer United States
Primary
Concomitant
Renal Cancer Metastatic Life Threatening 8/14/2011 70 Female 115 lb 1/15/2013 Physician Dk
Primary
Concomitant
Vomiting Other Serious 2012 81 Male 137 lb 9/7/2012 Consumer Br
Primary
Concomitant
Vascular Calcification 1/2012 66 Male 180 lb 2/21/2013 Consumer Us
Primary
Concomitant
Vertigo 2012 69 Male 229 lb 10/25/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/2/2008 73 Male 10/7/2012 Physician It
Primary
Concomitant
Vision Blurred Other Serious 2012 41 Male 190 lb 4/4/2013 Consumer Us
Primary
Concomitant
Interacting
Hepatic Function Abnormal Hospitalization 5/18/2012 61 Male 240 lb 11/27/2012 Physician Nl
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2012 57 Male 8/30/2012 Physician Us
Primary
Concomitant
Multi-organ Failure Death 3/2012 Male 9/24/2012 Consumer Br
Primary
Concomitant
Vomiting Other Serious 10/2/2012 48 Female 143 lb 12/14/2012 Consumer Us
Primary
Concomitant
Vomiting Hospitalization 8/2012 67 Male 213 lb 1/18/2013 Consumer Us
Primary
Concomitant
Pyrexia 9/9/2012 55 Female 170 lb 11/9/2012 Pharmacist Us
Primary
Concomitant
Weight Increased 8/2012 70 Female 150 lb 9/4/2012 Consumer Us
Primary
Concomitant
Vomiting Hospitalization 2012 72 Female 9/5/2012 Physician Us
Primary
Concomitant
Urinary Retention Hospitalization 2012 60 Male 163 lb 9/10/2012 Consumer Br
Primary
Concomitant
Weight Decreased Death 2012 62 Male 88 lb 12/24/2012 Consumer Br
Primary
Concomitant
Weight Decreased Other Serious 2012 49 Male 209 lb 9/26/2012 Consumer Us
Primary
Concomitant
Platelet Count Decreased Death 2012 75 Female 132 lb 9/27/2012 Consumer Br
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2012 65 Male 123 lb 4/23/2013 Consumer Us
Primary
Concomitant
Spinal Osteoarthritis Death 4/5/2012 10/10/2012 Consumer Us
Primary
Secondary
Concomitant
Weight Increased 2012 71 Female 177 lb 11/30/2012 Physician Us
Primary
Concomitant
Sleep Disorder Hospitalization 65 Male 187 lb 12/4/2012 Consumer Us
Primary
Concomitant
Hypertension Male 11/9/2012 Consumer Us
Primary
Concomitant
Yellow Skin Other Serious 11/2012 54 Male 186 lb 5/16/2013 Physician Us
Primary
Concomitant
Renal Function Test Abnormal 10/20/2012 71 Male 180 lb 11/23/2012 Consumer Us
Primary
Concomitant
Yellow Skin Other Serious 2012 64 Female 1/3/2013 Consumer Br
Primary
Concomitant
Skin Ulcer 2012 76 Female 249 lb 12/3/2012 Consumer Us
Primary
Concomitant
Weight Decreased 71 Male 220 lb 3/19/2013 Consumer Us
Primary
Secondary
Concomitant
Skin Wound Death 7/23/2012 69 Male 150 lb 12/10/2012 Consumer Br
Primary
Concomitant
Vomiting Other Serious 4/30/2012 73 Male 230 lb 4/9/2013 Consumer Us
Primary
Concomitant
Upper Respiratory Tract Infection 72 Female 3/21/2013 Consumer Us
Primary
Concomitant
Nausea Male 1/28/2013 Consumer Us
Primary
Concomitant
Rhabdomyolysis Other Serious 2/22/2013 57 Male 3/26/2013 Physician It
Primary
Secondary
Concomitant

Drug Data