Metformin combined with Sitagliptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Face Hospitalization 11/4/2008 84 Male 1/9/2009 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 Male 160 lb 2/27/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 Male 160 lb 3/4/2009 Consumer United States
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 1/31/2005 Male 9/18/2009 Lawyer United States
Primary
Concomitant
Cytolytic Hepatitis Death 6/30/2009 80 9/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 7/31/2009 Male 10/1/2009 Physician Puerto Rico
Primary
Secondary
Concomitant
Skull Fracture Other Serious 1/1/2009 Female 150 lb 10/30/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 10/31/2009 70 Male 309 lb 12/11/2009 Physician Germany
Primary
Concomitant
Vertigo Other Serious 10/31/2009 Male 309 lb 12/23/2009 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 9/8/2009 Female 258 lb 12/29/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 75 Female 1/15/2010 Physician United States
Primary
Secondary
Completed Suicide Death 75 Female 2/22/2010 United States
Primary
Secondary
Renal Impairment Other Serious 1/1/2010 Female 3/17/2010 Consumer United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/2/2009 67 Male 185 lb 4/5/2010 Consumer United States
Primary
Concomitant
Petechiae Life Threatening 80 Male 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/5/2009 62 Male 4/9/2010 Consumer Canada
Primary
Concomitant
Muscle Spasms Other Serious 12/1/2009 55 Female 4/21/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 3/28/2010 48 Female 4/28/2010 Physician United Kingdom
Primary
Concomitant
Premature Baby Other Serious 38 Male 5/31/2010 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 12/1/2009 55 Female 6/1/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 1/20/2003 61 Female 203 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/1/2006 73 Female 6/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Drug Ineffective 5/12/2009 74 Male 168 lb 6/29/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/11/2009 71 Female 184 lb 6/29/2010 Consumer United States
Primary
Concomitant
Nausea Other Serious 2/1/2008 41 Female 210 lb 7/21/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious Female 160 lb 7/28/2010 Consumer United States
Primary
Secondary
Concomitant
Rosacea Female 207 lb 7/31/2010 Consumer United States
Primary
Concomitant
Weight Increased 6/1/2009 49 Male 240 lb 8/4/2010 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2009 69 Female 283 lb 8/6/2010 Consumer United States
Primary
Concomitant
Stress 9/12/2009 63 Female 256 lb 8/10/2010 Physician United States
Primary
Concomitant
Drug Ineffective 7/1/2010 67 Male 162 lb 8/27/2010 Physician United States
Primary
Concomitant
Blood Glucose Increased 4/19/2010 66 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Hair Disorder Other Serious 1/1/2009 47 Male 200 lb 9/3/2010 Consumer United States
Primary
Concomitant
Nausea 7/18/2009 45 Female 189 lb 9/15/2010 Consumer United States
Primary
Concomitant
Cytolytic Hepatitis Death 6/30/2009 80 Male 9/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Skull Fracture Other Serious 1/1/2009 65 Female 150 lb 9/16/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2009 57 Male 9/17/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 73 Male 160 lb 9/24/2010 Consumer United States
Primary
Concomitant
Tachycardia Other Serious Female 10/6/2010 Other Health Professional Germany
Primary
Secondary
Proteinuria Other Serious 8/11/2010 55 Female 10/8/2010 Other Health Professional Brazil
Primary
Concomitant
Tachycardia Life Threatening 10/12/2010 Other Health Professional Germany
Primary
Secondary
Neuralgia Other Serious Male 202 lb 10/25/2010 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness Female 205 lb 10/26/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 8/23/2010 58 Male 175 lb 10/28/2010 Consumer United States
Primary
Concomitant
White Blood Cell Disorder Other Serious 10/1/2010 67 Male 194 lb 11/4/2010 Physician United States
Primary
Concomitant
Death Other Serious 10/1/2010 56 Female 210 lb 11/14/2010 Consumer United States
Primary
Concomitant
Sepsis Other Serious 9/10/2010 75 Male 192 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 10/30/2010 62 Female 203 lb 11/29/2010 Physician Germany
Primary
Concomitant
Drug Ineffective 5/1/2010 64 Male 260 lb 11/29/2010 Consumer United States
Primary
Concomitant
Cytolytic Hepatitis Death 6/30/2009 80 9/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Skull Fracture Other Serious 1/1/2009 65 Female 150 lb 10/30/2009 Consumer United States
Primary
Concomitant
Prostatomegaly Other Serious 1/1/2010 73 Male 244 lb 12/3/2010 United States
Primary
Secondary
Concomitant
Pruritus 9/16/2009 12/19/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 8/1/2009 12/22/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious Male 12/21/2010
Primary
Secondary
Fatigue Disability 1/1/2000 52 Female 98 lb 1/18/2011 Consumer United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 1/1/2011 75 Female 196 lb 1/17/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 45 Female 1/21/2011 Physician United States
Primary
Secondary
Gastritis Hospitalization 1/19/2011 67 Male 190 lb 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 1/16/2011 Male 258 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Coma Hospitalization 10/1/2010 65 Female 2/24/2011 Physician Portugal
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/4/2011 Physician Greece
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 3/8/2011 Physician Greece
Primary
Secondary
Concomitant
Drug Ineffective 3/6/2011 73 Male 160 lb 3/10/2011 Consumer United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 9/29/2010 65 Female 3/14/2011 Physician Portugal
Primary
Concomitant
Musculoskeletal Pain Other Serious 2/9/2011 35 Female 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Wall Haematoma Hospitalization 1/24/2011 84 Female 3/29/2011 Other Health Professional France
Primary
Concomitant
Interacting
Nausea 8/1/2009 37 Female 280 lb 4/4/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 1/24/2011 84 Female 4/11/2011 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 1/24/2011 84 Female 4/13/2011 Other Health Professional France
Primary
Concomitant
Interacting
Wheezing Other Serious 2/16/2011 77 Female 169 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rosacea Other Serious Female 207 lb 4/20/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 4/1/2011 52 Female 4/20/2011 Consumer Turkey
Primary
Concomitant
Gastrointestinal Disorder Other Serious 4/8/2011 Male 4/26/2011 Consumer France
Primary
Concomitant
Interacting
Amnesia Other Serious Female 225 lb 4/27/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/24/2011 73 Female 146 lb 4/28/2011 Physician Greece
Primary
Secondary
Concomitant
Constipation 4/14/2011 64 Female 190 lb 4/19/2011 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Other Serious 4/1/2011 68 Male 192 lb 5/6/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/24/2011 84 Female 6/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Nausea 6/19/2011 53 Female 183 lb 6/20/2011 Physician United States
Primary
Concomitant
Dizziness 6/19/2011 53 Female 183 lb 7/20/2011 Physician United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 4/1/2011 52 Female 8/2/2011 Consumer Turkey
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2003 22 Male 8/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Balance Disorder Hospitalization Male 8/18/2011 Consumer Canada
Primary
Concomitant
Pain Other Serious 3/4/2011 42 Male 337 lb 8/18/2011 Consumer United Kingdom
Primary
Concomitant
Anaemia Other Serious 1/1/2011 84 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Interacting
Drug Ineffective Other Serious 1/1/2009 47 Male 200 lb 9/19/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2011 84 Female 9/19/2011 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Decreased Other Serious 7/22/2011 10/28/2011 Physician United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2009 64 Female 12/27/2011 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Urticaria Papular Other Serious 3/18/2012 41 Male 174 lb 5/8/2012 Pharmacist United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 68 Male 6/1/2012 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 68 Male 6/1/2012 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Other Serious 68 Male 7/10/2012 Physician United States
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 68 Male 7/19/2012 Physician United States
Primary
Concomitant
Parkinson's Disease Other Serious Male 8/23/2012 Consumer Ireland
Primary
Concomitant
Schizophrenia Hospitalization 9/14/2012 38 Female 10/9/2012 Other Health Professional Au
Primary
Concomitant
Vomiting Hospitalization 3/28/2010 71 Male 134 lb 6/26/2013 Physician Au
Primary
Concomitant
Weight Decreased Other Serious 11/2011 69 Male 218 lb 4/22/2013 Consumer Gb
Primary
Concomitant
Laceration Hospitalization 5/21/2012 66 Male 229 lb 6/27/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 5/13/2012 77 Male 205 lb 10/8/2012 Physician Gb
Primary
Concomitant
Lung Neoplasm Malignant Death 10/2011 Male 273 lb 10/4/2012 Physician Fr
Primary
Secondary
Concomitant
Urticaria Hospitalization 8/23/2012 62 Male 227 lb 9/7/2012 Other Health Professional Gb
Primary
Concomitant
Urticaria Hospitalization 8/23/2012 62 Male 227 lb 9/18/2012 Physician Gb
Primary
Concomitant
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 8/23/2012 62 Male 227 lb 9/17/2012 Physician Gb
Primary
Concomitant
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 8/23/2012 62 Male 9/13/2012 Other Health Professional Dk
Primary
Concomitant
Pulmonary Embolism Other Serious 9/12/2012 50 Male 337 lb 10/11/2012 Consumer Gb
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 10/12/2012 71 Male 10/31/2012 Physician Ch
Primary
Concomitant
Abdominal Pain Other Serious Female 1/21/2013 Consumer Gb
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 5/14/2010 62 Male 132 lb 11/2/2012 Physician Tw
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2005 70 Male 195 lb 11/12/2012 Physician Gb
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 70 Male 195 lb 11/9/2012 Physician Gb
Primary
Secondary
Concomitant
Troponin Increased Other Serious 9/10/2012 47 Male 194 lb 11/14/2012 Other Health Professional Au
Primary
Concomitant
Renal Failure Hospitalization 60 Female 11/21/2012 Se
Primary
Concomitant
Vomiting Hospitalization 12/2012 47 Male 4/16/2013 Other Health Professional Ie
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/3/2012 71 Male 2/7/2013 Physician Fr
Primary
Secondary
Concomitant
Weight Increased Hospitalization 52 Male 12/4/2012 Other Health Professional Dk
Primary
Concomitant
Psychotic Disorder Hospitalization 11/21/2012 55 Male 185 lb 12/20/2012 Physician Gb
Primary
Concomitant
Somnolence Other Serious 12/18/2012 48 Female 1/8/2013 Other Health Professional Au
Primary
Concomitant
Rash Pruritic Other Serious 12/7/2012 53 Female 154 lb 12/29/2012 Physician Gb
Primary
Concomitant
Blood Glucose Increased Hospitalization 62 Male 292 lb 1/7/2013 Other Health Professional Gb
Primary
Concomitant
Amylase Abnormal Hospitalization 11/2012 64 Female 1/11/2013 Other Health Professional Gb
Primary
Concomitant
Lacunar Infarction Life Threatening 1/11/2013 67 NotSpecified 251 lb 2/7/2013 Other Health Professional Gb
Primary
Concomitant
Rheumatoid Arthritis Other Serious 56 Male 2/6/2013 Other Health Professional Dk
Primary
Concomitant
Rheumatoid Arthritis Other Serious 56 Male 2/4/2013 Pharmacist Gb
Primary
Concomitant
Rheumatoid Arthritis Other Serious 56 Male 2/11/2013 Pharmacist Gb
Primary
Concomitant
Rheumatoid Arthritis Other Serious 56 Male 2/12/2013 Other Health Professional Gb
Primary
Concomitant
Protrusion Tongue Hospitalization 55 Female 2/15/2013 Other Health Professional Kr
Primary
Concomitant
Hypogonadism Male Hospitalization 67 Male 3/14/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 66 Female 2/1/2013 Other Health Professional Country Not Specified
Primary
Secondary
Rheumatoid Arthritis Other Serious 56 Male 2/1/2013 Other Health Professional Gb
Primary
Concomitant
Injection Site Mass Other Serious 1/17/2013 53 Female 227 lb 1/31/2013 Consumer Gb
Primary
Concomitant
Gastrointestinal Carcinoma Hospitalization 3/2011 Male 3/19/2013 Other Health Professional Gb
Primary
Concomitant
Gynaecomastia Other Serious 67 Female 2/13/2013 Physician Us
Primary
Secondary
Concomitant
Completed Suicide Death 51 Female 2/18/2013 Physician Us
Primary
Secondary
Vomiting Hospitalization 2/21/2012 78 Female 2/26/2013 Physician Au
Primary
Concomitant
Hypogonadism Other Serious 67 Male 2/27/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Cardiac Disorder Hospitalization Male 145 lb 2/28/2013 Physician Us
Primary
Concomitant
Toxicity To Various Agents Death Female 3/1/2013 Other Health Professional Us
Primary
Secondary
Death Death Female 3/7/2013 Physician Us
Primary
Secondary
Death Other Serious Female 3/8/2013 Physician Us
Primary
Secondary
Endometrial Cancer Other Serious 54 Female 3/7/2013 Consumer Gb
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 56 Male 2/11/2013 Other Health Professional Dk
Primary
Concomitant
Spinal Cord Compression Hospitalization 1/17/2013 57 Male 154 lb 3/21/2013 Physician Au
Primary
Concomitant
Pancreatitis Other Serious 2/25/2013 56 Female 134 lb 3/18/2013 Physician Gb
Primary
Secondary
Concomitant
Presyncope Hospitalization 6/21/2012 56 Female 220 lb 3/14/2013 Pharmacist Us
Primary
Concomitant
Pancreatitis Other Serious 2/25/2013 56 Female 134 lb 3/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Syncope Other Serious 10/2/2012 42 Female 196 lb 11/2/2012 Consumer Gb
Primary
Concomitant
Pancreatitis Other Serious 2/25/2013 56 Female 134 lb 3/25/2013 Physician Gb
Primary
Secondary
Concomitant

Drug Data