Metformin combined with Singulair

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Leukocytosis Hospitalization 8/24/2004 61 Female 1/9/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/12/2006 58 Male 300 lb 1/12/2006 Pharmacist United States
Primary
Concomitant
Nervous System Disorder 54 3/7/2006 Consumer United States
Primary
Concomitant
Nervous System Disorder 54 3/7/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 8/1/2002 66 Female 110 lb 3/10/2006 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 55 Female 3/13/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 8/1/2002 66 Female 110 lb 3/17/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 2/18/2006 75 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 8/1/2002 66 Female 110 lb 3/22/2006 Physician United States
Primary
Concomitant
Herpes Zoster Hospitalization 2/18/2004 53 Male 3/27/2006 Physician United States
Primary
Concomitant
Leukopenia Other Serious 6/1/2005 53 Male 220 lb 3/28/2006 Physician United States
Primary
Concomitant
Leukocytosis Hospitalization 8/24/2004 61 Female 209 lb 3/30/2006 Physician United States
Primary
Concomitant
Vertebral Injury Hospitalization 6/22/2004 64 Female 276 lb 3/31/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/1/2005 49 Female 214 lb 3/27/2006 United States
Primary
Secondary
Concomitant
Aggression Hospitalization 3/1/2006 12 Female 141 lb 4/10/2006 Physician United States
Primary
Concomitant
Scar Hospitalization 2/18/2004 53 Male 254 lb 4/10/2006 Physician United States
Primary
Concomitant
Macular Degeneration Other Serious Male 4/27/2006 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 4/19/2006 31 Female 403 lb 4/27/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 3/12/2006 76 Male 126 lb 5/9/2006
Primary
Secondary
Concomitant
Macular Degeneration Other Serious Male 165 lb 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/3/2003 60 Female 176 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Tachycardia Other Serious 5/8/2006 58 Female 143 lb 5/16/2006 Consumer Brazil
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious Male 165 lb 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia 11/1/2005 42 Female 3/23/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 11/1/2005 54 Female 5/30/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/12/2006 76 Male 126 lb 6/7/2006
Primary
Secondary
Concomitant
Medical Device Complication Other Serious Male 165 lb 6/7/2006 Consumer United States
Primary
Secondary
Concomitant
Nasal Congestion 1/4/2006 32 Female 208 lb 4/17/2006 United States
Primary
Concomitant
Tooth Deposit 12/1/2005 61 Female 230 lb 4/17/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 69 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 6/8/2006 46 Female 206 lb 7/12/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Life Threatening 5/30/2006 58 Female 157 lb 8/3/2006 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Death 36 Female 250 lb 8/22/2006 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 4/1/2006 Female 11/21/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/8/2006 49 Female 183 lb 11/27/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Throat Irritation 1/1/2001 54 Female 12/8/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Overdose Death 5/3/2006 36 Female 196 lb 12/13/2006 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 12/11/2006 50 Female 1/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 6/1/2006 Male 124 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2005 63 Female 139 lb 4/13/2007 Physician United States
Primary
Secondary
Concomitant
Pruritus Disability 7/24/2007 54 Female 8/8/2007 Physician Japan
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 8/1/2007 74 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Furuncle 11/1/2006 60 Female 208 lb 8/16/2007 Physician United States
Primary
Concomitant
Cough 1/1/2007 64 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 10/19/2006 66 Female 10/25/2007 Consumer United States
Primary
Concomitant
Vocal Cord Disorder 11/1/2006 59 Female 246 lb 10/24/2007 Consumer United States
Primary
Concomitant
Hyposmia 2/1/2007 Male 11/5/2007 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/1/2000 46 Female 315 lb 11/9/2007 Other Health Professional United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/14/2000 46 Female 315 lb 12/21/2007 Other Health Professional United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/14/2000 46 Female 315 lb 2/21/2008 Other Health Professional United States
Primary
Concomitant
Device Occlusion Hospitalization 9/17/2007 61 Female 3/3/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 12/18/2007 Female 212 lb 3/17/2008 Consumer United States
Primary
Secondary
Concomitant
Tachycardia 10/1/2007 18 Female 269 lb 3/24/2008 Consumer United States
Primary
Concomitant
Application Site Rash 1/1/2008 66 Female 3/24/2008 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/26/2005 Female 314 lb 3/24/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 16 Female 4/8/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 16 Female 4/16/2008 Physician United States
Primary
Concomitant
Angioedema Other Serious Female 6/18/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2007 73 Female 185 lb 6/30/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/1/2008 53 Female 7/1/2008 Consumer United States
Primary
Concomitant
Foetal Heart Rate Abnormal Other Serious 7/22/2008 Consumer United States
Primary
Secondary
Fluid Retention 2/1/2007 58 Female 7/24/2008 Consumer United States
Primary
Concomitant
Muscle Spasms 43 Female 7/24/2008 Consumer United States
Primary
Secondary
Concomitant
Blood Thyroid Stimulating Hormone Increased 9/1/2007 Female 160 lb 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 1/1/2007 Female 259 lb 8/18/2008 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/1/2007 57 Female 8/27/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Disability 1/1/2008 54 Female 9/2/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 8/13/2008 57 Female 187 lb 9/25/2008 Physician United States
Primary
Concomitant
Alopecia 83 Female 140 lb 10/15/2008 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 72 Female 243 lb 1/12/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 11/26/2008 Male 249 lb 2/2/2009 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2005 61 Female 261 lb 2/2/2009 Physician United States
Primary
Concomitant
Resuscitation Other Serious 1/12/2009 Male 2/3/2009 Physician Canada
Primary
Concomitant
Blood Glucose Increased 12/1/2008 Male 2/24/2009 United States
Primary
Concomitant
Dizziness Male 2/24/2009 United States
Primary
Concomitant
Syncope Hospitalization Female 2/27/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/1/2006 58 Male 326 lb 3/6/2009 Consumer United States
Primary
Concomitant
Pain 2/14/2009 Male 3/20/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Life Threatening 7/9/2008 45 Female 271 lb 4/22/2009 Physician United States
Primary
Concomitant
Palpitations Hospitalization 73 Female 5/28/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 Female 165 lb 6/10/2009 Physician United States
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/10/2009 Ireland
Primary
Concomitant
Paraesthesia Hospitalization 4/1/2009 Male 237 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/24/2009 Ireland
Primary
Concomitant
Palpitations Hospitalization 70 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/6/2003 53 Female 278 lb 7/29/2009 United States
Primary
Concomitant
Epilepsy Other Serious 1/1/2003 38 Female 160 lb 7/27/2009 United States
Primary
Concomitant
Swelling Face Other Serious 6/3/2009 Female 7/29/2009 Consumer Switzerland
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1999 39 Male 258 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage 1/1/2009 Female 288 lb 7/29/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/4/2009 Consumer
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2001 44 Female 269 lb 8/5/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2004 40 Female 314 lb 8/10/2009 United States
Primary
Concomitant
Thirst Other Serious 41 Female 249 lb 8/12/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 242 lb 8/12/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/7/2007 73 Male 265 lb 8/5/2009 United States
Primary
Concomitant
Weight Increased Other Serious 7/31/2009 51 Female 197 lb 8/14/2009 Consumer United States
Primary
Concomitant
Interacting
Suicidal Ideation Other Serious 6/16/2009 Female 220 lb 8/17/2009 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 1/1/2009 Male 170 lb 8/17/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 10/13/2008 Female 254 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 1/1/2009 Male 170 lb 8/19/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2001 45 Male 8/20/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 186 lb 9/24/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/31/2009 51 Female 197 lb 9/29/2009 Consumer United States
Primary
Concomitant
Interacting
Vision Blurred Other Serious 70 Female 180 lb 10/2/2009 United States
Primary
Concomitant
Device Failure Other Serious 10/1/2009 50 Female 240 lb 10/7/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 9/8/2009 31 Female 10/21/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2003 62 Male 281 lb 10/21/2009 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/7/2007 73 Male 265 lb 11/4/2009 United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 11/17/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 12/30/2009 Physician United States
Primary
Concomitant
Urinary Tract Disorder Hospitalization 10/1/2009 59 Female 198 lb 1/1/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 5/1/2009 Female 1/5/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 173 lb 1/7/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2009 64 Female 1/11/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2009 64 Female 1/13/2010 Other Health Professional United States
Primary
Concomitant
Myalgia Disability 1/9/2009 69 Female 225 lb 1/6/2010 Consumer United States
Primary
Concomitant
Circulatory Collapse Other Serious 9/16/2009 Male 150 lb 1/18/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 211 lb 1/19/2010 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 12/1/2009 Female 252 lb 1/21/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 Female 1/22/2010 Physician United States
Primary
Concomitant
Umbilical Hernia Repair Other Serious 2/24/2003 Female 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/17/2009 Female 159 lb 1/29/2010 Other Health Professional Canada
Primary
Concomitant
Death Death Male 2/3/2010 Consumer United States
Primary
Concomitant
Wheezing Life Threatening 12/28/2009 52 Female 2/11/2010 Physician United States
Primary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2009 Female 2/19/2010 Consumer United States
Primary
Concomitant
Wheezing Life Threatening 12/28/2009 52 Female 2/24/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/1/2008 Female 172 lb 3/19/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious Female 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 9/1/2009 71 Male 4/8/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2009 58 Female 159 lb 4/27/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 7/1/2005 60 Male 154 lb 4/29/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 59 Female 222 lb 4/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Vaginal Discharge Disability 1/1/2006 61 Female 174 lb 5/6/2010 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 5/25/2007 59 Female 5/14/2010 Other Health Professional United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/14/2000 46 Female 315 lb 5/19/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 29 Female 274 lb 6/3/2010 United States
Primary
Concomitant
Tooth Erosion Hospitalization 1/1/2009 71 Male 240 lb 5/5/2010 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/1/2007 59 Female 6/9/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2009 65 Female 6/7/2010 Consumer United States
Primary
Concomitant
Skin Fibrosis Other Serious 5/1/2009 44 Female 245 lb 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Costochondritis 56 Female 228 lb 6/16/2010 United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization Male 6/15/2010 Consumer United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 4/24/2010 64 Female 211 lb 6/11/2010 Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 5/1/2009 44 Female 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data