Metformin combined with Rosuvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal Hospitalization 10/18/2005 78 Male 2/15/2006 Physician United Kingdom
Primary
Secondary
Iiird Nerve Paralysis Other Serious 3/1/2006 52 Male 4/5/2006 Germany
Primary
Concomitant
Vomiting Other Serious 3/1/2006 56 Female 150 lb 5/19/2006 United Kingdom
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 4/10/2006 56 Female 182 lb 6/26/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 4/9/2006 69 Female 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 9/8/2006 66 Female 167 lb 11/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious 61 Male 12/28/2006 United Kingdom
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 9/8/2006 66 Female 167 lb 1/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 11/1/2006 65 Male 226 lb 1/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Pacemaker Insertion Other Serious Male 3/5/2007 Physician United Kingdom
Primary
Concomitant
Skin Nodule Other Serious 8/1/2006 Male 258 lb 3/30/2007 Physician United Kingdom
Primary
Concomitant
Arthralgia Disability 6/1/2007 71 Female 224 lb 7/10/2007 Pharmacist United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 73 Female 9/24/2007 Pharmacist United States
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 51 Male 9/25/2007 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 48 Male 328 lb 10/16/2007 Physician United Kingdom
Primary
Concomitant
Drug Ineffective 11/1/2007 Female 180 lb 3/14/2008 Consumer United States
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 5/30/2009 Consumer United States
Primary
Concomitant
Palpitations 6/9/2008 Male 8/21/2009 United States
Primary
Concomitant
Feeling Abnormal 7/27/2008 Female 8/21/2009 United States
Primary
Concomitant
Blood Glucose Increased 6/30/2008 Male 8/21/2009 United States
Primary
Concomitant
Urticaria 9/14/2008 Male 8/21/2009 Consumer United States
Primary
Concomitant
Pruritus 9/20/2008 Female 8/21/2009 United States
Primary
Concomitant
Dizziness 9/28/2008 Male 8/22/2009 United States
Primary
Concomitant
Flushing 9/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Urticaria 10/8/2008 Male 219 lb 8/22/2009 Consumer United States
Primary
Concomitant
Medication Residue 7/1/2008 Female 198 lb 8/22/2009 United States
Primary
Secondary
Concomitant
Swelling Face 10/15/2008 Female 8/22/2009 United States
Primary
Concomitant
Arthralgia Male 8/22/2009 United States
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Dizziness 11/16/2008 160 lb 8/22/2009 Consumer United States
Primary
Concomitant
Cardiac Flutter 11/16/2008 Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Tuberculosis Other Serious 8/20/2009 50 Male 163 lb 10/20/2009
Primary
Concomitant
Tachycardia Life Threatening 10/6/2009 Female 12/29/2009 Consumer Australia
Primary
Concomitant
Hypokalaemia Life Threatening 11/24/2009 66 Female 209 lb 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 213 lb 4/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 4/22/2010 Germany
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 213 lb 4/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 213 lb 5/5/2010 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 213 lb 5/17/2010 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 213 lb 5/20/2010 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 6/11/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/10/2010 64 Female 6/11/2010 Physician Italy
Primary
Concomitant
Interacting
Myalgia Other Serious 72 Female 212 lb 6/5/2010 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 72 Female 213 lb 6/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Paradoxical Drug Reaction Other Serious 6/1/2006 72 Female 213 lb 6/18/2010 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2006 72 Female 214 lb 8/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tongue Oedema Life Threatening 3/20/2010 55 Female 196 lb 5/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Life Threatening 7/7/2010 61 Male 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/7/2010 61 Male 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Male 215 lb 8/27/2010 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/7/2010 61 Male 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 66 Male 9/20/2010 Physician Italy
Primary
Concomitant
Interacting
Alveolitis Allergic Hospitalization 7/27/2010 57 Female 126 lb 9/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/7/2010 44 Female 168 lb 9/24/2010 United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 60 Male 10/7/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 8/11/2010 55 Female 10/8/2010 Other Health Professional Brazil
Primary
Concomitant
Hypoperfusion Other Serious 8/13/2010 56 Male 10/8/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious Female 359 lb 10/11/2010 Physician Netherlands
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/3/2010 76 Female 10/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venous Injury Other Serious 9/16/2010 60 Male 324 lb 11/2/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 66 Male 11/10/2010 Physician Italy
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 9/1/2010 59 Female 12/2/2010 Consumer Brazil
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 1/16/2011 Male 258 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious Female 107 lb 2/22/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 9/1/2010 59 Female 3/8/2011 Consumer Brazil
Primary
Secondary
Concomitant
Intentional Drug Misuse Hospitalization 1/1/2009 62 Male 210 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Creatine Increased Hospitalization 11/1/2008 63 Male 243 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/5/2010 51 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Flank Pain Hospitalization 3/28/2011 62 Male 185 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 78 Female 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 4/1/2011 52 Female 4/20/2011 Consumer Turkey
Primary
Concomitant
Hyperglycaemia Other Serious 49 Female 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Diarrhoea Hospitalization 3/22/2011 78 Female 5/23/2011 Physician Colombia
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 56 Female 6/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Apolipoprotein A-i Decreased Other Serious 56 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 56 Female 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 4/1/2011 52 Female 8/2/2011 Consumer Turkey
Primary
Concomitant
Bladder Cancer Required Intervention 6/1/2011 62 Male 8/9/2011 Argentina
Primary
Concomitant
Treatment Failure Life Threatening 73 Male 236 lb 8/26/2011 Physician United States
Primary
Concomitant
Eye Swelling Other Serious 5/1/2011 57 Female 185 lb 9/7/2011 Consumer Hungary
Primary
Concomitant
Blood Urea Increased Other Serious Male 195 lb 11/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Non-cardiogenic Pulmonary Oedema Hospitalization 73 Female 236 lb 1/4/2012 Physician United States
Primary
Concomitant
Shock Hypoglycaemic Other Serious 10/15/2010 38 Female 159 lb 1/25/2012 Physician France
Primary
Concomitant
Interacting
Epistaxis Hospitalization 2/18/2012 77 Male 3/30/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/18/2012 77 Male 4/3/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Dysphagia Hospitalization 4/23/2012 72 Male 149 lb 5/18/2012 Physician United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 5/16/2012 Female 128 lb 7/31/2012 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 4/23/2012 72 Male 143 lb 8/13/2012 Physician United States
Primary
Secondary
Concomitant
Flank Pain Hospitalization 8/14/2012 66 Male 8/22/2012 Physician Australia
Primary
Concomitant
Fall Hospitalization 4/23/2012 72 Male 149 lb 8/27/2012 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/28/2010 71 Male 134 lb 6/26/2013 Physician Au
Primary
Concomitant
Myocardial Infarction Hospitalization 7/13/2009 65 Male 1/7/2013 Other Health Professional Us
Primary
Concomitant
Renal Failure Acute Hospitalization 8/6/2011 73 Female 216 lb 5/1/2013 Physician Us
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 3/5/2012 58 Male 268 lb 2/13/2013 Physician Us
Primary
Secondary
Concomitant
Swelling Hospitalization Female 165 lb 4/12/2013 Consumer Country Not Specified
Primary
Concomitant
Diverticulum Hospitalization 5/5/2012 57 Female 6/7/2013 Physician Country Not Specified
Primary
Concomitant
Thrombocytopenia Other Serious 6/2012 Male 227 lb 9/10/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Flank Pain Hospitalization 8/14/2012 66 Male 10/25/2012 Physician Au
Primary
Concomitant
Vomiting Other Serious 6/25/2012 67 Female 137 lb 10/26/2012 Consumer Country Not Specified
Primary
Concomitant
Hypoglycaemia Hospitalization 5/23/2012 60 Male 12/27/2012 Consumer Us
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 8/20/2012 Male 9/14/2012 Pharmacist Ca
Primary
Concomitant
Ulcer Other Serious 8/28/2012 78 Male 187 lb 9/17/2012 Other Health Professional Gb
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 65 Male 12/14/2012 Consumer Country Not Specified
Primary
Concomitant
International Normalised Ratio Increased Other Serious Male 10/8/2012 Consumer It
Primary
Concomitant
Eosinophil Count Increased Other Serious 9/18/2012 38 Male 12/10/2012 Physician Ie
Primary
Concomitant
Thrombocytopenia Death 6/16/2012 55 Male 2/15/2013 Physician Es
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/17/2012 76 Male 146 lb 10/19/2012 Pharmacist Gb
Primary
Concomitant
Tremor Other Serious 73 Male 10/26/2012 Other Health Professional Ro
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/24/2012 66 Male 12/3/2012 Physician Ca
Primary
Concomitant
Oromandibular Dystonia Other Serious 50 Female 11/12/2012 Physician Au
Primary
Concomitant
Intraocular Pressure Test Abnormal Other Serious 2011 78 Female 194 lb 1/22/2013 Consumer Br
Primary
Concomitant
Pancreatitis Other Serious Male 323 lb 12/5/2012 Consumer Ie
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/10/2012 68 Male 1/29/2013 Other Health Professional Au
Primary
Secondary
Concomitant
Drug Ineffective Male 12/14/2012 Consumer Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/3/2012 71 Male 2/7/2013 Physician Fr
Primary
Secondary
Concomitant
Viral Infection Other Serious 10/2012 Female 135 lb 12/14/2012 Physician Country Not Specified
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/22/2012 68 Female 12/21/2012 Physician Gb
Primary
Concomitant
Interacting
Tachycardia Hospitalization 12/5/2012 76 Female 12/28/2012 Other Health Professional Us
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/22/2012 68 Female 12/22/2012 Physician Gb
Primary
Secondary
Concomitant
Gastrointestinal Vascular Malformation Hospitalization 2/20/2009 51 Female 179 lb 1/2/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 62 Male 292 lb 1/7/2013 Other Health Professional Gb
Primary
Concomitant
Toxicity To Various Agents Death 31 Female 1/10/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 60 Male 1/9/2013 Physician Us
Primary
Secondary
Postoperative Wound Complication Hospitalization 2/2012 74 Female 4/9/2013 Physician Ca
Primary
Concomitant
Infusion Related Reaction Other Serious 1/21/2013 Female 207 lb 2/4/2013 Other Health Professional Ca
Primary
Concomitant
Oedema Peripheral Other Serious 7/2012 NotSpecified 3/14/2013 Consumer Ca
Primary
Concomitant
Respiratory Arrest Death 2011 60 Male 1/16/2013 Physician Us
Primary
Secondary
Vomiting Hospitalization 2/3/2013 58 Female 2/13/2013 Physician Np
Primary
Concomitant
Hypogonadism Male Hospitalization 67 Male 3/14/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Wrong Technique In Drug Usage Process 7/11/2012 67 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Musculoskeletal Pain Hospitalization Female 1/30/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/5/2012 75 Male 2/11/2013 Consumer Country Not Specified
Primary
Concomitant
Gynaecomastia Other Serious 67 Female 2/13/2013 Physician Us
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 2/2013 79 Female 183 lb 6/24/2013 Physician Us
Primary
Concomitant
Polyp Hospitalization 9/2012 74 Male 2/22/2013 Consumer Ca
Primary
Concomitant
Uterine Atrophy Other Serious 2012 60 Female 132 lb 1/16/2013 Consumer Ph
Primary
Secondary
Concomitant
Hypogonadism Other Serious 67 Male 2/27/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Death Death 60 Male 1/25/2013 Other Health Professional Us
Primary
Secondary
Respiratory Arrest Death 2011 60 Male 2/1/2013 Physician Us
Primary
Secondary
Haematochezia Hospitalization 1/22/2013 78 Male 135 lb 3/8/2013 Pharmacist Gb
Primary
Concomitant
Renal Impairment Hospitalization 2/2013 65 Male 227 lb 3/18/2013 Consumer Fr
Primary
Secondary
Concomitant
Trisomy 21 Other Serious NotSpecified 3/18/2013 Other Health Professional Ch
Primary
Secondary
Concomitant
Syncope Other Serious 10/2/2012 42 Female 196 lb 11/2/2012 Consumer Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/2012 Male 201 lb 3/28/2013 Other Health Professional Ie
Primary
Concomitant
Trisomy 21 Congenital Anomaly NotSpecified 3/26/2013 Other Health Professional Ch
Primary
Secondary
Trisomy 21 Congenital Anomaly NotSpecified 3/26/2013 Other Health Professional Ch
Primary
Secondary

Drug Data