Metformin combined with Rebif

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ejection Fraction Decreased Hospitalization 11/1/2006 58 Female 2/14/2007 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 12/1/2005 41 Female 3/2/2007 United States
Primary
Concomitant
Cholelithiasis Other Serious 1/1/2005 55 Female 3/19/2007 United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/23/2007 60 Female 4/2/2007 United States
Primary
Concomitant
Visual Disturbance Other Serious 7/1/2006 33 Female 4/4/2007 United States
Primary
Concomitant
Fatigue 60 Female 4/10/2007 Other Health Professional United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 51 Female 174 lb 5/18/2007 Physician United States
Primary
Concomitant
Thromboembolic Stroke Life Threatening 1/30/2007 48 Female 5/21/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 9/1/2006 62 Male 5/21/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection 3/1/2007 44 Female 5/29/2007 United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2007 47 Female 296 lb 5/29/2007 United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2007 47 Female 296 lb 6/12/2007 Physician United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 5/31/2008 Female 294 lb 7/11/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/1/2009 49 Female 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 3/1/2010 51 Female 6/3/2010 Brazil
Primary
Concomitant
Blindness Disability 12/1/2009 52 Female 8/20/2010 Consumer United States
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 1/1/2003 48 Female 258 lb 8/23/2010 Physician United States
Primary
Concomitant
Pollakiuria Hospitalization Female 9/2/2010 Consumer Brazil
Primary
Concomitant
Urinary Incontinence 8/1/2010 52 Female 9/10/2010 Consumer Brazil
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2010 53 Female 9/16/2010 Consumer United States
Primary
Concomitant
Joint Sprain Hospitalization 1/1/2010 44 Female 181 lb 9/21/2010 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/3/2010 47 Female 9/22/2010 Consumer Brazil
Primary
Concomitant
Urinary Incontinence Other Serious 8/1/2010 52 Female 9/22/2010 Consumer Brazil
Primary
Concomitant
Stress Other Serious 10/1/2009 28 Female 9/23/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2010 46 Male 10/8/2010 Consumer United States
Primary
Concomitant
Cholecystectomy Hospitalization 3/1/2010 57 Female 10/8/2010 Consumer Brazil
Primary
Concomitant
Syncope Hospitalization 2/15/2009 73 Female 141 lb 10/8/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 48 Female 10/11/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 9/1/2010 60 Male 205 lb 10/15/2010 Consumer United States
Primary
Concomitant
Transfusion Hospitalization 1/1/2010 44 Female 181 lb 10/15/2010 Consumer United States
Primary
Concomitant
Rib Fracture Hospitalization 1/1/2010 61 Female 176 lb 10/25/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 8/1/2010 52 Female 10/26/2010 Consumer Brazil
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2009 30 Female 216 lb 11/8/2010 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/1/2010 49 Male 11/8/2010 Consumer United States
Primary
Secondary
Concomitant
Cytogenetic Abnormality Congenital Anomaly 1/1/2009 11/8/2010 Physician United States
Primary
Concomitant
Turner's Syndrome Congenital Anomaly 1/1/2008 11/8/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2008 29 Female 216 lb 11/8/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2010 51 Male 229 lb 11/10/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 168 lb 11/11/2010 Consumer United States
Primary
Concomitant
Injection Site Erythema Other Serious 1/1/2010 39 Female 11/12/2010 Physician
Primary
Concomitant
Vomiting Other Serious 6/1/2010 47 Female 187 lb 12/3/2010 Other Health Professional Netherlands
Primary
Concomitant
Renal Cancer Other Serious Male 12/3/2010 Consumer Brazil
Primary
Concomitant
Renal Cancer Other Serious 10/12/2009 46 Male 12/8/2010 Consumer Brazil
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/1/2010 60 Female 190 lb 12/10/2010 Consumer United States
Primary
Concomitant
Renal Cancer Other Serious 10/12/2009 46 Male 185 lb 12/15/2010 Consumer Brazil
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2010 50 Female 12/16/2010 Consumer United States
Primary
Concomitant
Optic Nerve Disorder Hospitalization 12/1/2009 37 Female 313 lb 12/16/2010 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 44 Female 12/20/2010 Other Health Professional Australia
Primary
Concomitant
Renal Impairment Hospitalization 11/1/2010 33 Male 245 lb 12/23/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2010 56 Male 12/23/2010 Consumer United States
Primary
Concomitant
Stress Other Serious 1/1/2010 18 Female 245 lb 12/23/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2010 57 Female 194 lb 12/23/2010 Physician United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization 1/1/2010 44 Female 181 lb 1/11/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 43 Female 238 lb 1/20/2011 Physician United States
Primary
Concomitant
Pain Hospitalization 1/1/2010 50 Female 1/27/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious Male 1/31/2011 Consumer Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2006 29 Female 252 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 1/1/2010 44 Female 2/9/2011 Physician Sweden
Primary
Concomitant
Stress Other Serious 10/1/2009 28 Female 2/10/2011 Consumer United States
Primary
Concomitant
Influenza Like Illness Hospitalization 12/7/2010 56 Female 176 lb 2/14/2011 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 11/1/2010 33 Male 245 lb 2/18/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2011 53 Male 3/8/2011 Other Health Professional Canada
Primary
Concomitant
Influenza Like Illness Other Serious 1/1/2011 53 Male 3/15/2011 Other Health Professional Canada
Primary
Concomitant
Off Label Use Other Serious 9/1/2010 54 Female 3/24/2011 Consumer Brazil
Primary
Concomitant
Injection Site Erythema Female 4/6/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2006 29 Female 252 lb 4/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious Female 4/18/2011 Other Health Professional United States
Primary
Concomitant
Self-injurious Ideation Other Serious 3/8/2011 49 Female 4/20/2011 Consumer United States
Primary
Concomitant
Arrhythmia Hospitalization 6/1/2010 47 Female 187 lb 4/21/2011 Consumer Netherlands
Primary
Concomitant
Pancreatitis Hospitalization 3/26/2011 41 Male 4/26/2011 Other Health Professional United States
Primary
Concomitant
Hypothyroidism Other Serious 1/1/2010 44 Female 4/29/2011 Physician Sweden
Primary
Concomitant
Spinal Column Stenosis Other Serious 5/1/2010 49 Female 8/17/2011 Consumer Canada
Primary
Concomitant
Malaise Other Serious 5/18/2011 52 Male 301 lb 8/18/2011 United States
Primary
Concomitant
Balance Disorder Hospitalization Male 8/18/2011 Consumer Canada
Primary
Concomitant
Fall Hospitalization 8/20/2011 71 Female 9/1/2011 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Life Threatening 6/1/2011 67 Male 9/1/2011 Consumer Brazil
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 3/1/2009 56 Female 6/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 3/1/2009 56 Female 6/28/2012 Physician United States
Primary
Secondary
Concomitant
Intracranial Aneurysm Hospitalization 7/2009 59 Female 220 lb 9/24/2013 Other Health Professional Us
Primary
Concomitant
Neck Pain Hospitalization 2011 Female 287 lb 4/1/2013 Other Health Professional Us
Primary
Concomitant
Premature Rupture Of Membranes Hospitalization 5/2011 Female 152 lb 11/12/2012 Physician Us
Primary
Concomitant
Multiple Sclerosis Hospitalization 8/20/2011 71 Female 9/13/2012 Other Health Professional Us
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/9/2012 Physician Us
Primary
Concomitant
Thyroid Disorder Hospitalization 2011 Female 165 lb 10/3/2012 Other Health Professional Us
Primary
Concomitant
Weight Decreased Hospitalization 6/2011 Female 161 lb 10/10/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Somnolence Other Serious 10/2011 52 Female 190 lb 7/2/2013 Consumer Us
Primary
Concomitant
Uterine Cancer Other Serious Female 269 lb 9/28/2012 Physician Us
Primary
Concomitant
Foot Fracture Other Serious 5/2011 Female 181 lb 10/10/2012 Consumer Us
Primary
Concomitant
Mobility Decreased Disability 12/2011 Female 152 lb 10/15/2012 Physician Us
Primary
Concomitant
Uterine Cyst Other Serious 12/2011 Female 293 lb 10/16/2012 Other Health Professional Us
Primary
Concomitant
Uterine Cyst Other Serious 2013 Female 293 lb 8/15/2013 Other Health Professional Us
Primary
Concomitant
Influenza Like Illness Female 10/11/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Pain Other Serious Female 1/25/2013 Consumer Br
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 3/2012 Female 10/10/2012 Other Health Professional Us
Primary
Concomitant
Weight Decreased Other Serious 4/2012 44 Male 229 lb 6/10/2013 Pharmacist Us
Primary
Concomitant
Pain In Extremity Other Serious Female 311 lb 9/14/2012 Other Health Professional Us
Primary
Concomitant
Pain In Extremity Other Serious 8/2012 Female 12/28/2012 Consumer Us
Primary
Concomitant
Malaise Other Serious 8/5/2012 51 Female 9/13/2012 Consumer Gb
Primary
Secondary
Thrombosis Hospitalization 2006 Female 9/14/2012 Pharmacist Us
Primary
Concomitant
Malaise Other Serious 8/5/2012 50 Female 9/18/2012 Consumer Gb
Primary
Secondary
Optic Neuritis Other Serious 3/2012 Female 3/27/2013 Consumer Us
Primary
Concomitant
Temporomandibular Joint Syndrome Other Serious Female 10/8/2012 Consumer Us
Primary
Secondary
Myalgia Other Serious 9/2012 Female 12/6/2012 Consumer Us
Primary
Concomitant
Myalgia Other Serious 9/2012 55 Female 8/7/2013 Consumer Us
Primary
Concomitant
Paraesthesia 1/12/2012 Female 10/19/2012 Pharmacist Us
Primary
Concomitant
Pyrexia Other Serious 10/11/2012 66 Female 10/29/2012 Consumer Br
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/3/2012 50 Male 12/3/2012 Other Health Professional Gb
Primary
Concomitant
Pyrexia Other Serious 10/2012 Female 163 lb 2/5/2013 Other Health Professional Us
Primary
Concomitant
Sjogren's Syndrome Other Serious 2005 Female 12/14/2012 Consumer Us
Primary
Concomitant
Staphylococcal Infection Other Serious 10/2012 49 Female 4/16/2013 Physician Us
Primary
Concomitant
Blood Glucose Increased Other Serious 11/2012 Female 12/26/2012 Other Health Professional Us
Primary
Concomitant
Myocardial Infarction Death 8/25/2012 62 Male 12/7/2012 Physician Us
Primary
Concomitant
Suicidal Ideation Other Serious 11/2012 Female 12/17/2012 Consumer Us
Primary
Concomitant
Vision Blurred Hospitalization 10/30/2011 47 Female 2/25/2013 Consumer Br
Primary
Concomitant
Hypertensive Nephropathy Hospitalization 7/2012 Male 3/1/2013 Consumer Us
Primary
Concomitant
Hepatic Cirrhosis Other Serious Female 190 lb 10/31/2012 Consumer Us
Primary
Concomitant
Hyperhidrosis Death 2012 Male 12/28/2012 Consumer Us
Primary
Concomitant
Sepsis Hospitalization 1/2013 44 Male 8/1/2013 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 10/2012 Female 205 lb 2/7/2013 Consumer Us
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 12/1/2012 44 Female 6/13/2013 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 10/22/2012 Female 130 lb 3/3/2013 Physician Gb
Primary
Concomitant
Multiple Sclerosis Other Serious 2012 Female 3/8/2013 Consumer Us
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2011 Female 207 lb 5/1/2013 Physician De
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 6/2/2011 59 Female 3/13/2013 Other Health Professional Us
Primary
Concomitant
Injection Site Pain Other Serious Female 229 lb 3/18/2013 Physician Us
Primary
Concomitant
Pain Other Serious 4/2013 48 Female 227 lb 9/16/2013 Consumer Us
Primary
Concomitant
Gingival Disorder 2013 Female 198 lb 5/20/2013 Consumer Us
Primary
Concomitant
Prostate Cancer Other Serious 2012 Male 5/16/2013 Consumer Us
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/7/2013 55 Male 225 lb 5/25/2013 Consumer Us
Primary
Concomitant
Muscular Weakness Other Serious 2012 Female 5/19/2013 Consumer Br
Primary
Concomitant
Pneumothorax Other Serious 2012 43 Female 5/23/2013 Other Health Professional Br
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 9/24/2012 67 Female 5/30/2013 Consumer Br
Primary
Concomitant
Vaginal Prolapse Hospitalization 3/2013 51 Female 201 lb 7/5/2013 Physician Us
Primary
Concomitant
Vomiting Other Serious 3/2013 49 Male 6/18/2013 Consumer Us
Primary
Concomitant
Paraesthesia Hospitalization 3/2013 60 Female 6/19/2013 Pharmacist Us
Primary
Concomitant
Visual Impairment Female 6/20/2013 Pharmacist Us
Primary
Concomitant
Bronchitis Male 278 lb 6/20/2013 Pharmacist Us
Primary
Concomitant
Injection Site Swelling 3/1/2011 58 Female 170 lb 6/20/2013 Pharmacist Us
Primary
Concomitant
Pruritus 4/19/2013 36 Female 185 lb 6/21/2013 Pharmacist Us
Primary
Concomitant
Disease Progression Female 6/21/2013 Pharmacist Us
Primary
Concomitant
Pain In Extremity 4/9/2012 41 Male 6/21/2013 Pharmacist Us
Primary
Concomitant
Peroneal Nerve Palsy 9/12/2012 44 Female 181 lb 6/21/2013 Pharmacist Us
Primary
Concomitant
Hepatic Enzyme Increased 5/24/2012 59 Female 130 lb 6/21/2013 Pharmacist Us
Primary
Concomitant
Paraesthesia Male 220 lb 6/22/2013 Pharmacist Us
Primary
Concomitant
Pruritus 4/9/2013 47 Female 220 lb 6/22/2013 Pharmacist Us
Primary
Concomitant
Antibody Test Positive Female 260 lb 6/22/2013 Pharmacist Us
Primary
Concomitant
Ovarian Neoplasm Hospitalization Female 8/1/2013 Other Health Professional Us
Primary
Concomitant
Convulsion Other Serious Female 205 lb 7/12/2013 Other Health Professional Us
Primary
Concomitant
Urinary Tract Infection Other Serious Female 9/13/2013 Consumer Br
Primary
Secondary
Concomitant

Drug Data