Metformin combined with Ramipril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 5/28/2005 73 Male 196 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Septic Shock Other Serious 6/1/2005 55 Female 1/23/2006 Physician Sweden
Primary
Concomitant
Pallor Hospitalization 9/1/2005 60 Female 174 lb 2/3/2006 Consumer United Kingdom
Primary
Concomitant
Hemiparesis Other Serious 9/1/2004 36 Female 2/6/2006 Physician United Kingdom
Primary
Concomitant
Injection Site Ulcer Other Serious 2/13/2006 51 Male 249 lb 3/2/2006 Other Health Professional Canada
Primary
Concomitant
Melaena Hospitalization 77 Male 2/23/2006 United Kingdom
Primary
Secondary
Concomitant
Pallor Hospitalization 9/1/2005 60 Female 165 lb 3/3/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 2/13/2006 2/27/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 1/1/2001 61 Male 2/27/2006 Physician Canada
Primary
Concomitant
Pallor Hospitalization 9/1/2005 60 Female 165 lb 3/10/2006 Physician United Kingdom
Primary
Concomitant
Catheter Related Complication Other Serious 3/3/2004 62 Male 209 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Urticaria Disability 4/30/2005 49 Male 215 lb 12/21/2005 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 5/28/2005 73 Male 196 lb 3/17/2006 Other Health Professional France
Primary
Secondary
Vomiting Life Threatening 2/13/2006 57 Male 3/29/2006 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/21/2006 Female 110 lb 4/6/2006 Consumer Canada
Primary
Concomitant
Renal Impairment Life Threatening 2/13/2006 57 Male 3/29/2006 Physician United Kingdom
Primary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Sinus Arrest Life Threatening 3/14/2006 68 Male 108 lb 4/7/2006 South Africa
Primary
Concomitant
Syncope Other Serious 65 Male 4/12/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 5/4/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/13/2006 78 Male 5/8/2006 Other Health Professional France
Primary
Secondary
Syncope Other Serious 65 Male 5/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/1/2005 71 Female 158 lb 5/17/2006 Canada
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2004 72 Male 187 lb 5/11/2006 Physician India
Primary
Concomitant
Vomiting Hospitalization 56 Female 5/19/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 67 Male 5/26/2006 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 12/24/2004 47 Male 176 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 12/22/2004 57 Male 210 lb 5/26/2006 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2004 44 Female 291 lb 5/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypernatraemia Required Intervention 62 Female 6/8/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 5/11/2006 57 Female 6/26/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 74 Male 7/6/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 60 Male 207 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Prostate Cancer Other Serious 4/24/2006 74 Male 7/12/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 4/24/2006 70 Male 7/6/2006 France
Primary
Secondary
Concomitant
Head Injury Hospitalization 95 Male 7/11/2006 Pharmacist United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 4/25/2005 61 Female 132 lb 7/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 4/24/2006 70 Male 7/14/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/11/2006 57 Female 7/21/2006 United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 5/9/2006 46 Male 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 7/11/2006 66 Female 179 lb 8/4/2006 Physician Germany
Primary
Concomitant
Transurethral Prostatectomy Other Serious 4/24/2006 74 Male 8/17/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 3/15/2006 59 Female 172 lb 8/11/2006 Physician France
Primary
Concomitant
Hyperkalaemia Other Serious 4/3/2006 61 Male 8/22/2006 Pharmacist Australia
Primary
Concomitant
Lethargy Life Threatening 55 Male 8/16/2006 United Kingdom
Primary
Concomitant
Lethargy Life Threatening 55 Male 176 lb 8/23/2006 United Kingdom
Primary
Concomitant
Death Death 8/12/2006 Female 182 lb 9/25/2006 Physician
Primary
Concomitant
Angina Pectoris Hospitalization 1/10/2006 Female 154 lb 9/26/2006 Physician United Kingdom
Primary
Concomitant
Pituitary Infarction Other Serious 62 Female 10/23/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 11/25/2005 67 Male 159 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 12/18/2005 74 Male 206 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 10/1/2006 76 Female 185 lb 11/10/2006 Physician Germany
Primary
Concomitant
Metabolic Acidosis Life Threatening 9/21/2006 71 Female 165 lb 11/6/2006 United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/8/2006 78 Female 187 lb 11/13/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2006 88 Female 12/2/2006 United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/12/2006 65 Female 114 lb 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Life Threatening 10/7/2002 58 Female 12/15/2006 Physician United States
Primary
Concomitant
Death Death 8/12/2006 Female 182 lb 1/16/2007 Physician
Primary
Concomitant
Hallucination, Visual Other Serious 12/5/2006 71 Male 1/20/2007 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 4/3/2006 61 Male 2/14/2007 Pharmacist Australia
Primary
Concomitant
Procedural Pain Other Serious 11/25/2006 74 Female 259 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Muscle Spasms Disability 1/1/2007 Male 4/10/2007 Physician Germany
Primary
Concomitant
Vomiting Other Serious 3/2/2007 80 Female 115 lb 4/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 3/1/2007 Male 4/11/2007 United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 6/20/2007 United Kingdom
Primary
Secondary
Concomitant
Bipolar I Disorder Hospitalization 6/8/2007 56 Female 234 lb 7/5/2007
Primary
Concomitant
Pharyngeal Oedema Other Serious 8/1/2007 74 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 1/1/2007 Female 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ischaemia Hospitalization 6/1/2007 52 Male 204 lb 9/24/2007 Physician Canada
Primary
Concomitant
Toxic Shock Syndrome Life Threatening 7/15/2007 67 Male 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Toxic Shock Syndrome Life Threatening 7/15/2007 67 Male 10/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Life Threatening 6/12/2007 54 Female 217 lb 10/23/2007 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 9/26/2007 62 Female 10/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vasculitic Rash Hospitalization 46 Male 10/26/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 9/27/2007 42 Male 10/26/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Myocardial Infarction Other Serious 6/13/2006 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 11/1/2005 77 Female 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Hypertensive Crisis Hospitalization 12/14/2007 54 Male 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 73 Male 1/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypertensive Crisis Hospitalization 12/14/2007 54 Male 1/30/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/31/2007 76 Male 2/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pseudomonas Infection Disability 11/1/2005 Female 194 lb 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 3/14/2008 Physician United States
Primary
Secondary
Pain In Extremity 8/19/2007 Female 150 lb 3/14/2008 Consumer United States
Primary
Concomitant
Sinusitis 1/26/2008 Male 260 lb 3/15/2008 United States
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 256 lb 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 68 Male 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Phosphorus Increased Hospitalization 5/8/2008 66 Female 5/15/2008 Pharmacist United Kingdom
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypokalaemia Life Threatening 4/12/2008 77 Male 154 lb 6/5/2008 Physician Germany
Primary
Concomitant
Hypersensitivity Hospitalization 70 Female 6/20/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Anoxic Encephalopathy Other Serious 5/15/2008 Female 245 lb 7/11/2008 Physician Israel
Primary
Concomitant
Completed Suicide Death 37 Female 7/11/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/3/2008 Female 7/23/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Malaise Other Serious 5/16/2007 Female 182 lb 7/23/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Distress Other Serious 5/15/2008 Female 245 lb 7/24/2008 Physician Israel
Primary
Concomitant
Drug Interaction Hospitalization 65 Female 7/28/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/24/2008 40 Female 8/4/2008 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 6/10/2008
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2008 Male 8/21/2008 Canada
Primary
Concomitant
Renal Cancer Life Threatening 2/1/2008 Female 203 lb 8/25/2008 Physician Germany
Primary
Concomitant
Pain Other Serious 1/1/2008 72 Male 198 lb 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 6/8/2008 60 Male 240 lb 9/10/2008 Physician France
Primary
Concomitant
Hypersensitivity Hospitalization 70 Female 9/11/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2007 Male 205 lb 9/13/2008 Physician Germany
Primary
Concomitant
Rhabdomyolysis Death 81 Male 9/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/24/2008 40 Female 159 lb 9/26/2008 Physician Germany
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 6/1/2008 52 Female 152 lb 10/13/2008 Physician France
Primary
Concomitant
Loss Of Consciousness Other Serious 9/29/2008 Male 267 lb 10/16/2008 Consumer United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 10/14/2008 Male 10/22/2008 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 55 Male 220 lb 10/23/2008 Lawyer United States
Primary
Concomitant
Urticaria Life Threatening 67 Male 238 lb 11/26/2008 Consumer United Kingdom
Primary
Concomitant
Musculoskeletal Disorder Hospitalization 10/24/2008 74 Male 12/16/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 1/14/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Flushing 179 lb 1/15/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Death 10/11/2008 Male 220 lb 1/15/2009 Germany
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/16/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 11/1/2008 Male 252 lb 1/16/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 60 Male 205 lb 1/21/2009 United States
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 12/19/2008 74 Female 1/22/2009 Physician France
Primary
Secondary
Concomitant
Syncope Life Threatening 5/26/2008 1/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 1/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Depression Other Serious 11/4/2008 70 Female 183 lb 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 69 Male 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 43 Male 2/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 12/8/2008 Female 2/9/2009 Physician Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 2/12/2009 Physician United Kingdom
Primary
Concomitant
Depression Other Serious 11/4/2008 70 Female 183 lb 2/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 43 Male 2/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 43 Male 2/3/2009 United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 6/4/2008 67 Male 193 lb 2/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 43 Male 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Male 2/24/2009 United States
Primary
Concomitant
Tuberculosis Life Threatening 11/13/2007 43 Male 130 lb 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 6/4/2008 67 Male 3/5/2009 Physician Germany
Primary
Concomitant

Drug Data