Metformin combined with Propranolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Required Intervention 35 Female 174 lb 12/28/2005 Consumer United States
Primary
Concomitant
Road Traffic Accident Death 1/25/2006 48 Male 3/6/2006 United States
Primary
Concomitant
Catatonia Hospitalization 3/6/2006 Male 181 lb 3/17/2006 Physician India
Primary
Concomitant
Road Traffic Accident Death 1/25/2006 48 Male 3/23/2006 United States
Primary
Concomitant
Hypokinesia Hospitalization 3/6/2006 Male 181 lb 4/7/2006 Physician India
Primary
Concomitant
Oedema Other Serious 3/13/2006 80 Male 162 lb 5/17/2006 Physician Canada
Primary
Concomitant
Lethargy Hospitalization 4/23/2006 77 Male 208 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Rectal Polyp Disability 1/15/2006 48 Female 168 lb 5/22/2006 Pharmacist Netherlands
Primary
Concomitant
Rectal Polyp Disability 1/15/2006 48 Female 168 lb 6/20/2006 Pharmacist Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/24/2006 64 Female 190 lb 6/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal 12/1/2005 54 Female 190 lb 4/17/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased Female 7/21/2006 Consumer United States
Primary
Concomitant
Gallbladder Disorder Other Serious 56 Female 7/25/2006 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 6/24/2006 64 Female 190 lb 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Initial Insomnia 5/17/2006 76 Female 135 lb 7/12/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/3/2006 55 Female 228 lb 11/3/2006 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 6/21/2007 Male 6/22/2007 Pharmacist United States
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 12/1/2006 69 Female 198 lb 9/24/2007 Consumer United Kingdom
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 9/28/2007 Consumer Brazil
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 9/28/2007 Consumer Brazil
Primary
Concomitant
Back Pain 11/7/2006 62 Female 183 lb 9/20/2007 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 55 Female 139 lb 10/25/2007 Consumer Brazil
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/1/2007 17 Male 166 lb 12/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence 5/1/2006 Female 6/17/2008 Consumer United States
Primary
Concomitant
Migraine Hospitalization 3/1/2008 Female 6/17/2008 Physician United States
Primary
Concomitant
Weight Increased 80 Female 7/24/2008 Consumer United States
Primary
Concomitant
Scab Hospitalization 8/15/1997 Female 172 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 1/26/2009 Female 270 lb 2/5/2009 Consumer United States
Primary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Concomitant
Laceration Hospitalization 7/1/2008 67 Male 176 lb 3/9/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 11/19/2001 42 Male 210 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 64 Female 7/7/2009 United States
Primary
Concomitant
Interacting
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Migraine 8/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Sensory Disturbance 1/1/1998 Male 8/22/2009 United States
Primary
Concomitant
Nocturia Other Serious 8/19/2009 56 9/9/2009 Consumer Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/6/2009 Male 195 lb 10/7/2009 United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 56 10/9/2009 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2002 56 Male 216 lb 11/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/6/2009 Male 195 lb 11/14/2009 United States
Primary
Concomitant
Diarrhoea Hospitalization 12/5/2009 Female 142 lb 12/15/2009 Physician Chile
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2009 Female 220 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 154 lb 1/28/2010 Brazil
Primary
Concomitant
Diarrhoea Hospitalization 12/5/2009 Female 142 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 60 Female 165 lb 2/22/2010 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/20/2010 72 Male 156 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/20/2010 72 Male 156 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 11/1/2009 60 Male 171 lb 4/8/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2002 54 Male 216 lb 4/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 4/2/2010 43 Male 256 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2009 60 Male 171 lb 4/21/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2009 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 4/12/2010 52 Female 201 lb 4/29/2010 Consumer Mexico
Primary
Concomitant
Haemorrhoidal Haemorrhage Other Serious 1/1/2009 54 Female 129 lb 5/7/2010 United States
Primary
Concomitant
Tobacco User Other Serious 11/1/2009 60 Male 171 lb 5/26/2010 Other Health Professional
Primary
Secondary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 41 Male 6/7/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Female 6/16/2010 Other Health Professional United States
Primary
Concomitant
Nausea 5/1/2007 60 Female 211 lb 7/13/2010 Consumer United States
Primary
Concomitant
Nausea 5/1/2007 64 Female 150 lb 7/13/2010 Other Health Professional United States
Primary
Concomitant
Flushing 1/1/2007 49 Female 165 lb 8/27/2010 United States
Primary
Concomitant
Paraesthesia 8/1/2009 62 Male 214 lb 8/27/2010 United States
Primary
Concomitant
Rash 10/21/2009 61 Male 180 lb 8/28/2010 United States
Primary
Concomitant
Heart Rate Increased 2/1/2010 63 Male 8/28/2010 United States
Primary
Concomitant
Blood Glucose Increased 4/1/2010 73 Male 245 lb 8/29/2010 United States
Primary
Concomitant
Throat Irritation 7/19/2010 Male 8/29/2010 Consumer United States
Primary
Concomitant
Poisoning Deliberate Hospitalization 7/27/2010 65 Female 8/20/2010 France
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/28/2000 45 Female 325 lb 9/8/2010 United States
Primary
Concomitant
Lip Swelling Other Serious 8/31/2010 64 Male 250 lb 9/9/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 46 Male 167 lb 9/15/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 48 Female 212 lb 9/17/2010 United States
Primary
Concomitant
Epilepsy Other Serious Male 325 lb 9/20/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/6/2005 37 Male 222 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 41 Male 315 lb 9/20/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 66 Male 204 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 8/1/2010 59 Female 242 lb 10/1/2010 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 37 Female 10/12/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/1/2007 76 Male 172 lb 10/14/2010 Lawyer United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2006 Male 168 lb 10/29/2010 Consumer Brazil
Primary
Concomitant
Diarrhoea Hospitalization 9/1/2010 54 Male 198 lb 11/12/2010 Other Health Professional Canada
Primary
Concomitant
Spondylitis Other Serious 37 Female 11/18/2010 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 10/28/2010 64 Male 139 lb 11/18/2010 United Kingdom
Primary
Concomitant
Tremor Hospitalization 4/11/2009 54 Male 165 lb 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness 53 Female 360 lb 12/14/2010 Consumer United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly Female 5 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spondylitis Other Serious Female 12/28/2010 Consumer United States
Primary
Concomitant
Medication Residue 60 Female 1/7/2011 Physician United States
Primary
Concomitant
Pain Other Serious 10/1/2008 37 Female 1/14/2011 Consumer United States
Primary
Secondary
Concomitant
Agitation Other Serious 10/1/2008 37 Female 1/18/2011 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2002 34 Female 205 lb 1/20/2011 Consumer United States
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 12/19/2010 70 Male 500 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia Other Serious 12/1/2010 43 Female 137 lb 2/7/2011 Consumer Brazil
Primary
Concomitant
Gastric Haemorrhage Hospitalization 11/21/2010 67 Male 132 lb 2/21/2011 Consumer United States
Primary
Secondary
Concomitant
Nodal Arrhythmia Hospitalization 12/27/2010 81 Female 146 lb 1/26/2011 Pharmacist United States
Primary
Concomitant
Malaise Hospitalization 12/1/2010 67 Male 3/2/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 12/1/2010 76 Male 3/14/2011 Other Health Professional France
Primary
Concomitant
Interacting
Palpitations Other Serious 6/1/2007 48 Female 230 lb 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Akathisia Other Serious 1/1/1984 32 Female 115 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Epistaxis Hospitalization 10/28/2009 48 Male 176 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Dysuria Hospitalization 5/1/2002 54 Male 220 lb 3/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Injury Other Serious Female 280 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Chronic Other Serious Female 280 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 9/23/2009 49 Female 4/14/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/1/2011 54 Female 154 lb 4/20/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 11/21/2010 67 Male 132 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 4/16/2011 63 Male 5/4/2011 Pharmacist Canada
Primary
Concomitant
Cognitive Disorder Other Serious 5/18/2008 53 Female 250 lb 5/21/2011 Consumer United States
Primary
Concomitant
Lip Swelling Other Serious 6/15/2011 73 Female 229 lb 9/13/2011 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2011 73 Female 229 lb 9/19/2011 Consumer United States
Primary
Concomitant
Pain Death 8/1/2005 42 Female 257 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2010 36 Male 380 lb 9/22/2011 Physician United States
Primary
Concomitant
Dermal Cyst 1/1/2001 35 Female 195 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2011 73 Female 229 lb 10/19/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2007 54 Male 220 lb 10/19/2011 Consumer Brazil
Primary
Secondary
Concomitant
Constipation Other Serious 1/1/2011 73 Female 229 lb 10/27/2011 Physician United States
Primary
Concomitant
Rash Other Serious 1/1/2009 51 Male 235 lb 1/17/2012 Consumer United States
Primary
Concomitant
Angioedema Hospitalization 12/21/2011 84 Male 211 lb 12/22/2011 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/22/2011 68 Male 200 lb 1/23/2012 Physician United States
Primary
Concomitant
Abnormal Dreams 9/1/2011 49 Male 239 lb 2/1/2012 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious 2/3/2012 51 Male 359 lb 2/8/2012 Consumer United States
Primary
Concomitant
Mood Altered 7/14/2011 48 Male 238 lb 2/9/2012 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 56 Female 3/14/2012 Physician Brazil
Primary
Concomitant
Blood Glucose Increased 1/1/2011 72 Male 194 lb 4/2/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2012 62 Female 309 lb 4/18/2012 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 4/1/2012 62 Female 309 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Tremor 1/1/2011 50 Female 201 lb 5/22/2012 Consumer United States
Primary
Concomitant
Pain 1/1/2012 Female 5/24/2012 Consumer United States
Primary
Concomitant
Drug Screen False Positive 7/17/2012 56 Male 163 lb 7/23/2012 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 6/1/2012 63 Male 305 lb 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious Male 8/23/2012 Consumer Ireland
Primary
Concomitant
Tremor 2003 62 Female 181 lb 11/13/2012 Consumer Us
Primary
Concomitant
Deep Vein Thrombosis Other Serious 3/21/2009 39 Female 182 lb 9/20/2012 Consumer Us
Primary
Concomitant
Feeling Abnormal 42 Female 9/20/2012 Physician Us
Primary
Concomitant
Glycosylated Haemoglobin Increased 9/2012 73 Female 236 lb 11/14/2012 Physician Us
Primary
Concomitant
Sinusitis Other Serious 8/9/2012 66 Female 165 lb 10/23/2012 Consumer Br
Primary
Concomitant
Injection Site Erythema 7/5/2012 52 Female 186 lb 10/26/2012 Consumer Us
Primary
Concomitant
Fluid Retention Other Serious 2011 43 Female 11/5/2012 Consumer Us
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/27/2010 27 Female 3/15/2013 Consumer Us
Primary
Concomitant
Off Label Use 2012 65 Female 208 lb 11/15/2012 Consumer Us
Primary
Concomitant
Pain 11/2012 52 Female 175 lb 11/15/2012 Consumer Us
Primary
Concomitant
Urinary Incontinence Hospitalization 9/18/2012 52 Female 157 lb 11/13/2012 Pharmacist Us
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2012 67 Male 139 lb 11/26/2012 Other Health Professional Br
Primary
Concomitant
Syncope Other Serious 2012 Female 233 lb 12/19/2012 Consumer Us
Primary
Secondary
Concomitant
Wound Other Serious 11/19/2012 68 Female 139 lb 12/17/2012 Country Not Specified
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 7/2/2011 60 Male 9/10/2012 Physician Se
Primary
Secondary
Concomitant

Drug Data