Metformin combined with Perindopril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenic Purpura Hospitalization 8/14/2002 Male 1/4/2006 Australia
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 7/24/2002 Male 1/4/2006 Australia
Primary
Concomitant
Malaise Other Serious 60 Male 2/6/2006 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 60 Male 4/3/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 12/22/2005 60 Male 4/4/2006 Physician South Africa
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 61 Male 4/28/2006 Physician Czech Republic
Primary
Concomitant
Depressed Mood Other Serious 1/1/2006 65 Female 5/25/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 7/19/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 1/30/2006 69 Female 132 lb 7/20/2006 United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Decreased Other Serious 5/18/2006 70 Female 8/22/2006 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 3/28/2007 44 Male 185 lb 5/16/2007 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 71 Male 5/16/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 10/14/2005 52 Female 11/5/2007 Other Health Professional Latvia
Primary
Secondary
Concomitant
Chest Pain Hospitalization 7/1/2007 47 Male 187 lb 11/29/2007 Physician France
Primary
Concomitant
Rhabdomyolysis Other Serious 1/10/2008 54 Male 216 lb 2/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Poor Quality Sleep Other Serious 1/1/2008 63 Male 223 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 6/8/2008 Male 476 lb 6/13/2008 Consumer United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 50 Male 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 12/16/2007 Female 6/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 3/1/2008 75 Male 165 lb 6/17/2008 Pharmacist China
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2008 75 Male 165 lb 6/23/2008 Pharmacist China
Primary
Concomitant
Syncope Life Threatening 6/1/2008 66 Male 7/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 7/15/2008 72 Female 187 lb 8/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 8/5/2008 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 73 Female 134 lb 9/3/2008 Physician France
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 1/1/2008 66 Female 9/9/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 1/1/2008 66 Female 9/10/2008 Pharmacist Australia
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2008 82 Male 10/1/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2007 63 Female 130 lb 10/17/2008 Physician Saudi Arabia
Primary
Concomitant
Intentional Overdose Hospitalization 10/4/2008 Male 245 lb 10/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 11/8/2008 71 Male 12/3/2008 Physician France
Primary
Concomitant
Hypoglycaemia Other Serious 11/1/2008 56 Male 12/26/2008 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 11/1/2008 56 Male 265 lb 1/16/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/1/2007 57 Female 1/19/2009 Physician Australia
Primary
Concomitant
Swollen Tongue Hospitalization 1/1/2008 66 Female 1/26/2009 Pharmacist Australia
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2008 66 Male 170 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Hospitalization 1/1/2008 66 Female 1/28/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 11/8/2008 71 Male 2/6/2009 Physician France
Primary
Concomitant
Myalgia Other Serious 1/1/2006 3/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 11/28/2008 3/23/2009 Physician Malaysia
Primary
Concomitant
Hypertensive Crisis Other Serious 11/8/2008 71 Male 4/1/2009 Physician France
Primary
Concomitant
Stomatitis Life Threatening 3/19/2009 4/8/2009 Physician Romania
Primary
Secondary
Concomitant
Syncope Life Threatening 6/1/2008 66 Male 4/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 65 Male 154 lb 6/17/2009 Portugal
Primary
Concomitant
Ascites Hospitalization 11/28/2008 62 6/29/2009 Physician Malaysia
Primary
Concomitant
Periorbital Oedema Other Serious 7/1/2008 6/30/2009 Other Health Professional Malaysia
Primary
Concomitant
Arterial Haemorrhage Hospitalization 6/20/2009 Female 7/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vasculitic Rash Other Serious 3/1/2009 64 Female 194 lb 7/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Arterial Haemorrhage Hospitalization 6/20/2009 Female 7/31/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 181 lb 8/4/2009 Physician Netherlands
Primary
Secondary
Concomitant
Mastitis Other Serious 10/1/2008 39 Female 8/7/2009 Physician Netherlands
Primary
Concomitant
Hypercalcaemia Life Threatening 3/19/2009 71 9/11/2009 Physician Romania
Primary
Secondary
Concomitant
Syncope Life Threatening 6/1/2008 66 Male 11/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Syncope Life Threatening 6/7/2008 66 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 9/15/2009 Female 227 lb 11/3/2009 Physician Malaysia
Primary
Concomitant
Syncope Life Threatening 6/7/2008 66 Male 11/4/2009 United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 71 Female 11/24/2009 Physician United Kingdom
Primary
Secondary
Syncope Life Threatening 6/1/2008 66 Male 3/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 9/6/2009 Male 3/19/2010 Other Health Professional Australia
Primary
Concomitant
Rectal Haemorrhage Other Serious 4/19/2010 75 Male 5/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 4/19/2010 75 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 6/1/2010 78 Male 6/14/2010 Pharmacist Canada
Primary
Concomitant
Weight Decreased Disability 1/1/2010 55 Male 223 lb 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Life Threatening 7/7/2010 61 Male 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/7/2010 61 Male 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/7/2010 61 Male 9/3/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/7/2010 61 Male 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/30/2010 57 Male 9/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Joint Arthroplasty Other Serious 3/16/2010 74 Female 10/11/2010 Pharmacist United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 7/7/2010 61 Male 10/15/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2009 66 Male 10/15/2010 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 10/1/2010 51 Female 139 lb 10/22/2010 Consumer Brazil
Primary
Concomitant
Radius Fracture Hospitalization 12/16/2007 72 Female 159 lb 10/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Joint Arthroplasty Hospitalization 3/16/2010 74 Female 10/31/2010 Pharmacist United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 7/7/2010 61 Male 11/29/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Cerebral Infarction Death 12/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/7/2010 66 Male 12/6/2010 Physician Germany
Primary
Secondary
Concomitant
Troponin Increased Other Serious 8/28/2009 55 Male 12/9/2010 Pharmacist Australia
Primary
Concomitant
Nephrotic Syndrome Hospitalization 11/11/2010 61 Male 214 lb 12/14/2010 Physician Belgium
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 11/11/2010 61 Male 214 lb 12/21/2010 Physician Belgium
Primary
Secondary
Concomitant
Gastritis Hospitalization 1/19/2011 67 Male 190 lb 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Life Threatening 10/5/2010 70 Male 2/4/2011 Physician Netherlands
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 1/30/2011 71 Female 2/4/2011 Physician France
Primary
Concomitant
Vertigo Other Serious 1/30/2011 71 Female 2/11/2011 Physician France
Primary
Concomitant
Nephrotic Syndrome Death 11/11/2010 61 Male 214 lb 2/11/2011 Physician Belgium
Primary
Secondary
Concomitant
Myopathy Hospitalization 2/3/2011 69 Male 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ileus Paralytic Other Serious 75 Male 3/9/2011 Other Health Professional Spain
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/25/2010 78 Male 3/22/2011 Physician Canada
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 56 Male 3/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 47 Female 4/4/2011 Brunei Darussalam
Primary
Secondary
Concomitant
Drug Interaction Other Serious 83 Female 4/19/2011 Physician Hungary
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 52 Female 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Malaise Hospitalization Male 4/21/2011 Netherlands
Primary
Concomitant
Haemorrhage Other Serious 83 Female 4/25/2011 Physician Hungary
Primary
Secondary
Concomitant
Agitation Other Serious 62 Male 194 lb 4/27/2011 Pharmacist Canada
Primary
Concomitant
Drug Interaction Other Serious 83 Female 4/27/2011 Other Health Professional Hungary
Primary
Concomitant
Interacting
Haemorrhage Other Serious 83 Female 4/27/2011 Other Health Professional Hungary
Primary
Concomitant
Interacting
Blood Alkaline Phosphatase Increased Other Serious 75 Female 190 lb 4/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Other Serious 83 Female 4/28/2011 Physician Hungary
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 83 Female 5/1/2011 Other Health Professional Hungary
Primary
Concomitant
Interacting
Skin Disorder Other Serious 12/1/2010 79 Male 176 lb 5/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Skin Disorder Other Serious 12/1/2010 79 Male 176 lb 5/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Nephrotic Syndrome Hospitalization 11/11/2010 61 Male 214 lb 6/8/2011 Physician Belgium
Primary
Secondary
Concomitant
Pruritus Hospitalization 5/4/2011 67 Female 6/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/11/2010 74 Female 7/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Nephrotic Syndrome Death 11/11/2010 61 Male 214 lb 7/26/2011 Physician Belgium
Primary
Secondary
Concomitant
Eye Swelling Other Serious 5/1/2011 57 Female 185 lb 9/7/2011 Consumer Hungary
Primary
Concomitant
Back Pain Disability 9/20/2011 77 Male 179 lb 10/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Hospitalization 67 Male 12/1/2011 Physician France
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 1/1/2009 64 Female 12/27/2011 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Compulsive Sexual Behaviour Other Serious 11/21/2011 77 Male 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 83 Female 1/6/2012 Hungary
Primary
Concomitant
Interacting
Weight Decreased Other Serious 10/28/2011 62 Male 190 lb 1/18/2012 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 11/11/2011 58 Female 5/14/2012 Physician United Kingdom
Primary
Concomitant
Mobility Decreased Disability 64 Male 159 lb 5/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 4/30/2012 71 Male 6/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 77 Female 172 lb 3/20/2013 Other Health Professional Gb
Primary
Concomitant
Somnolence 6/2/2012 60 Female 203 lb 10/9/2012 Consumer Gb
Primary
Concomitant
Rash Hospitalization 8/5/2012 85 Female 162 lb 11/1/2012 Other Health Professional Ca
Primary
Concomitant
Eyelid Tumour Other Serious Male 150 lb 8/28/2012 Consumer Ca
Primary
Concomitant
Vomiting Hospitalization 8/16/2012 50 Male 8/29/2012 Physician Au
Primary
Concomitant
Adenocarcinoma Pancreas Life Threatening 1/2012 58 Female 220 lb 11/1/2012 Physician Be
Primary
Concomitant
Eosinophil Count Increased Other Serious 9/18/2012 38 Male 12/10/2012 Physician Ie
Primary
Concomitant
Hyponatraemia Hospitalization 9/5/2012 80 9/26/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Vomiting Other Serious 8/4/2012 72 Male 201 lb 10/1/2012 Physician Gb
Primary
Secondary
Concomitant
Vomiting Other Serious 8/4/2012 72 Male 201 lb 10/11/2012 Physician Gb
Primary
Secondary
Concomitant
Respiratory Failure Death 9/21/2012 75 Female 123 lb 11/5/2012 Physician Hk
Primary
Concomitant
Vomiting Death 8/4/2012 72 Male 201 lb 10/8/2012 Physician Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/19/2012 61 Male 10/9/2012 Consumer Za
Primary
Concomitant
Vomiting Death 8/4/2012 72 Male 201 lb 10/11/2012 Physician Gb
Primary
Secondary
Concomitant
Vomiting Death 8/4/2012 72 Male 201 lb 10/10/2012 Physician Gb
Primary
Secondary
Concomitant
Vomiting Death 8/4/2012 72 Male 201 lb 10/11/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Malaise Hospitalization 9/12/2012 59 Male 153 lb 11/26/2012 Physician Gb
Primary
Secondary
Concomitant
Malaise Life Threatening 9/12/2012 59 Male 153 lb 11/30/2012 Physician Gb
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/19/2012 46 Male 1/10/2013 Physician Au
Primary
Concomitant
Cerebrovascular Accident Hospitalization 56 Female 183 lb 10/30/2012 Pharmacist Ca
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/24/2012 66 Male 12/3/2012 Physician Ca
Primary
Concomitant
Purpura Hospitalization 8/1/2012 11/5/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 5/27/2012 74 Male 245 lb 11/19/2012 Physician Gb
Primary
Concomitant
Vascular Calcification Other Serious 4/30/2012 84 Female 11/30/2012 Physician Gb
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/4/2012 64 Male 12/10/2012 Physician Ca
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/2012 80 Female 1/28/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Rash Generalised Other Serious 11/20/2012 48 Female 185 lb 12/14/2012 Consumer Gb
Primary
Concomitant
Weight Increased Hospitalization 9/4/2012 64 Male 12/21/2012 Physician Ca
Primary
Concomitant
Vomiting Hospitalization 12/7/2012 63 Male 1/4/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Tremor Disability 10/11/2012 47 Male 150 lb 1/4/2013 Physician Gb
Primary
Concomitant
Vomiting Hospitalization 12/7/2012 63 Male 1/2/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 2/18/2012 71 Female 119 lb 11/6/2012 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data