Metformin combined with Paracetamol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pituitary Tumour Benign Hospitalization 12/13/2001 Female 1/4/2006 Australia
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/23/2005 50 Male 201 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Yawning Other Serious 2/28/2006 85 Female 200 lb 5/22/2006 United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/27/2006 76 Female 209 lb 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Mental Disorder Hospitalization 9/1/2006 58 Male 7/3/2007 Physician Sweden
Primary
Secondary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Polyarthritis Other Serious 9/19/2007 Male 10/24/2007 Physician Netherlands
Primary
Concomitant
Vomiting 11/1/2007 Female 224 lb 3/14/2008 Consumer United States
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 256 lb 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/2/2008 2/4/2009 Physician France
Primary
Concomitant
Pneumonia Hospitalization 11/26/2008 Female 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 12/5/2008 Female 278 lb 2/27/2009 Consumer United Kingdom
Primary
Concomitant
Osteomyelitis Other Serious 2/16/2009 Male 222 lb 4/1/2009 Consumer United Kingdom
Primary
Concomitant
Anal Abscess Hospitalization 3/30/2009 4/7/2009 Pharmacist Brazil
Primary
Concomitant
Anal Abscess Other Serious 3/30/2009 4/20/2009 Brazil
Primary
Concomitant
Anal Abscess Hospitalization 3/30/2009 51 5/15/2009 Pharmacist Brazil
Primary
Concomitant
Malaise Other Serious 4/24/2009 Female 7/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 6/8/2009 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 8/21/2009 Other Health Professional New Zealand
Primary
Secondary
Sepsis Death 10/31/2007 84 9/28/2009 Other Health Professional New Zealand
Primary
Concomitant
Pneumonia Hospitalization 10/11/2008 Male 10/1/2009 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/7/2009 Female 10/1/2009 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 71 Female 10/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 3/25/2009 71 Male 174 lb 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 6/7/2008 66 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/7/2008 66 Male 11/4/2009 United Kingdom
Primary
Secondary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 11/24/2009 United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2008 52 Female 12/29/2009 Consumer Brazil
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 10/8/2009 Male 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/23/2009 1/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 63 Male 231 lb 1/8/2010 Other Health Professional Austria
Primary
Secondary
Urine Output Decreased Other Serious 1/15/2008 70 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 2/3/2010 63 Male 2/12/2010 Physician Germany
Primary
Concomitant
Liver Injury Hospitalization 1/18/2010 88 Female 2/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/4/2010 63 Male 2/25/2010 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 9/1/2009 54 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 8/1/2008 Female 3/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 9/1/2009 54 Male 3/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/11/2010 77 Female 3/26/2010 Physician Spain
Primary
Concomitant
Tachycardia Hospitalization 9/1/2009 54 Male 3/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Petechiae Life Threatening 80 Male 4/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Other Serious 79 Male 4/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Body Temperature Decreased Other Serious 5/12/2009 69 Male 198 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Proteinuria Other Serious 11/4/2008 67 Female 146 lb 4/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gastritis Hospitalization 10/23/2009 67 Male 125 lb 5/6/2010 Physician Brazil
Primary
Secondary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2009 Male 6/4/2010 Pharmacist Germany
Primary
Concomitant
Linear Iga Disease Hospitalization 4/6/2010 87 Female 6/4/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 6/8/2010 52 Male 189 lb 6/14/2010 Brazil
Primary
Concomitant
Anal Abscess Hospitalization 4/10/2010 52 Male 189 lb 7/16/2010 Pharmacist Brazil
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Delirium Hospitalization 8/18/2009 75 Female 196 lb 7/23/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 7/29/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 38 Female 176 lb 8/24/2010 Consumer Brazil
Primary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 9/16/2010 United Kingdom
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Miosis Other Serious 7/27/2010 75 Male 162 lb 9/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 9/13/2010 60 Female 220 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Miosis Other Serious 7/27/2010 75 Male 10/1/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Drug Administration Error Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/7/2010 44 Female 168 lb 9/24/2010 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 7/11/2001 79 Male 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/2/2009 55 Female 244 lb 10/7/2010 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 8/18/2009 53 Male 145 lb 10/7/2010 Consumer United States
Primary
Secondary
Concomitant
Pruritus Death 7/22/2004 68 Male 187 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Death 2/10/2010 76 Female 203 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Arthroplasty Other Serious 3/16/2010 74 Female 10/11/2010 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 6/22/2010 63 Male 225 lb 10/12/2010 Physician Australia
Primary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 6/6/2005 56 Female 150 lb 10/14/2010 Physician United Kingdom
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 203 lb 10/6/2010 Other Health Professional
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 9/27/2010 88 Female 108 lb 10/14/2010 Physician Spain
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Other Serious 9/15/2010 55 Female 10/21/2010 Physician United States
Primary
Concomitant
Radius Fracture Hospitalization 12/16/2007 72 Female 159 lb 10/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Joint Arthroplasty Hospitalization 3/16/2010 74 Female 10/31/2010 Pharmacist United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/6/2010 79 Male 11/1/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 8/6/2010 73 Male 11/22/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 9/15/2009 49 Male 211 lb 11/24/2010 Physician Ireland
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 10/14/2010 56 Male 357 lb 11/30/2010 Physician Mexico
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wrong Drug Administered Other Serious 10/14/2010 56 Male 357 lb 12/8/2010 Physician Mexico
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/14/2010 Consumer United Kingdom
Primary
Concomitant
Multiple Drug Overdose Death 63 Female 265 lb 12/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 10/26/2010 82 Female 12/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neuralgia Life Threatening 10/9/2009 88 Male 11/24/2009 United Kingdom
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 52 Female 12/29/2009 Consumer Brazil
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious Female 12/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 9/1/2010 65 Male 12/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 10/26/2010 82 Female 12/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 10/26/2010 82 Female 12/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/22/2010 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 11/9/2010 77 Male 12/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/19/2010 56 Male 234 lb 12/28/2010 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/6/2010 73 Male 12/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 10/26/2010 82 Female 12/15/2010 Other Health Professional Denmark
Primary
Concomitant
Serotonin Syndrome Death 63 Female 265 lb 12/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 12/23/2010 71 Female 1/20/2011 Physician New Zealand
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/25/2011 51 Male 2/8/2011 Consumer United States
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 1/30/2011 41 Male 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Hospitalization 2/3/2011 69 Male 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/25/2011 51 Male 3/10/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/19/2010 56 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cholestasis Hospitalization 1/6/2011 83 Male 3/22/2011 Consumer France
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 12/1/2010 36 Female 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Bacterial Infection Other Serious 12/1/2010 36 Female 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 1/1/2009 86 Female 4/7/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Magnesium Decreased Hospitalization 10/19/2009 72 Female 4/8/2011 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 11/9/2010 77 Male 4/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 75 Female 4/17/2011 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 75 Female 4/17/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 72 Female 4/18/2011 Physician United Kingdom
Primary
Concomitant
Disturbance In Attention Hospitalization 3/22/2011 79 Female 4/21/2011 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Drug Interaction Hospitalization 1/25/2011 74 Female 5/4/2011 Other Health Professional France
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 4/7/2010 77 Female 220 lb 5/4/2011 Consumer Germany
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 4/16/2011 63 Male 5/4/2011 Pharmacist Canada
Primary
Concomitant
Skin Disorder Other Serious 12/1/2010 79 Male 176 lb 5/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Circulatory Collapse Other Serious 3/30/2011 81 Male 256 lb 5/5/2011 Other Health Professional Netherlands
Primary
Concomitant
Skin Disorder Other Serious 12/1/2010 79 Male 176 lb 5/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lung Carcinoma Cell Type Unspecified Stage 0 Death 1/20/2010 63 Male 271 lb 5/27/2011 Physician United Kingdom
Primary
Concomitant
Renal Impairment Death 1/20/2010 63 Male 271 lb 6/10/2011 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 12/19/2010 56 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Hospitalization 87 Female 7/5/2011 Physician Spain
Primary
Concomitant
Interacting
Insomnia Other Serious 8/23/2011 37 Female 344 lb 9/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2011 37 Female 344 lb 9/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2011 37 Female 344 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/9/2012 65 Female 295 lb 2/28/2012 Physician Netherlands
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 2/1/2012 66 Female 154 lb 6/21/2012 Consumer Brazil
Primary
Concomitant
Neuroendocrine Tumour Other Serious 68 Female 8/20/2012 Physician Norway
Primary
Concomitant
Hepatitis Fulminant Hospitalization 10/7/2010 65 Male 11/6/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/28/2011 74 Male 190 lb 10/2/2012 Physician Au
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 11/3/2011 75 Female 3/21/2013 Physician Es
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 9/12/2011 75 Male 9/13/2012 Physician Gb
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/15/2012 55 Female 9/24/2012 Other Health Professional Gb
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/18/2012 61 Male 240 lb 11/27/2012 Physician Nl
Primary
Secondary
Concomitant

Drug Data