Metformin combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 12/1/2005 Female 164 lb 1/31/2006 Other Health Professional Canada
Primary
Concomitant
Wheezing Other Serious 73 Male 170 lb 2/7/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious Male 2/15/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
Sinusitis Hospitalization 11/29/2005 62 Male 229 lb 3/15/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Diabetes Mellitus Inadequate Control 45 Female 129 lb Physician United States
Primary
Concomitant
Somnolence Other Serious 4/26/2006 45 Male 5/4/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 10/1/2005 79 Female 170 lb 4/20/2006 United States
Primary
Concomitant
Neuropathy Other Serious 60 Female 250 lb 4/20/2006 Physician United States
Primary
Concomitant
Hypertension Other Serious 47 Male 260 lb 6/8/2006 United States
Primary
Concomitant
Neuropathy Peripheral Disability 2/10/2006 56 Male 270 lb 4/24/2006 United States
Primary
Concomitant
Vomiting Other Serious 74 Female 6/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 12/18/2005 Male 194 lb 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 5/1/2006 Male 205 lb 12/13/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 12/18/2005 Male 194 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Faecal Incontinence Hospitalization 1/11/2007 80 Male 159 lb 1/25/2007 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased 8/9/2006 59 Male 227 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Increased 60 Female 5/17/2007 Other Health Professional United States
Primary
Concomitant
Limb Injury Other Serious 7/23/2007 Male 225 lb 9/24/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 12/21/2007 Male 238 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/21/2007 Male 238 lb 1/21/2008 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 73 Female 3/13/2008 Consumer Canada
Primary
Secondary
Concomitant
Somnolence Hospitalization 12/18/2005 74 Male 206 lb 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/28/2008 69 Female 3/13/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 38 Male 198 lb 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased 44 Male 230 lb 7/24/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Male 9/16/2008 Consumer United States
Primary
Concomitant
Death Death 8/31/2008 Female 10/8/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 36 Male 235 lb 10/23/2008 Lawyer United States
Primary
Concomitant
Haematuria Hospitalization 12/31/2008 58 Female 1/19/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2008 74 Female 2/20/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 7/24/2008 Female 163 lb 2/26/2009 Physician France
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/1/2006 58 Male 250 lb 3/6/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/1/2006 58 Male 326 lb 3/6/2009 Consumer United States
Primary
Concomitant
Hypoaesthesia Facial Hospitalization 3/3/2009 63 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 3/2/2008 78 Female 7/21/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Death 3/2/2008 78 Female 8/5/2009 United States
Primary
Concomitant
Feeling Hot 12/9/2008 Female 8/22/2009 United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 9/24/2009 Female 198 lb 10/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 5/25/2009 Male 180 lb 11/6/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/12/2009 Male 177 lb 11/24/2009 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 11/18/2009 Female 140 lb 12/14/2009 Canada
Primary
Concomitant
Paraesthesia Other Serious 11/18/2009 Female 140 lb 12/29/2009 Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Death 5/1/2009 Female 1/5/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/1989 41 Male 2/12/2010 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Death 10/2/2009 54 Male 194 lb 3/5/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 Female 174 lb 3/11/2010 Other Health Professional Canada
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 Male 174 lb 3/22/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2010 60 Male 355 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 2/1/2010 38 Female 4/19/2010 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 59 Male 6/3/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 59 Female 135 lb 6/3/2010 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 10/2/2009 54 Male 194 lb 6/11/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 5/30/2010 Male 6/14/2010 Physician United States
Primary
Concomitant
Throat Irritation 11/1/2008 48 Female 144 lb 6/30/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/13/2010 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 5/1/2007 56 Male 190 lb 7/13/2010 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2007 45 Female 241 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 7/29/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 79 Male 8/2/2010 Other Health Professional
Primary
Secondary
Concomitant
Pain Other Serious 5/1/2010 57 Female 300 lb 8/10/2010 Physician Canada
Primary
Concomitant
Death Death 7/15/2010 64 Male 218 lb 8/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 8/23/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 8/8/2008 56 Male 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Death 7/15/2010 64 Male 218 lb 8/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 79 Male 8/17/2010 Other Health Professional
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 9/8/2010 United States
Primary
Concomitant
Somnolence Hospitalization 7/11/2001 79 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Hospitalization 79 Male 9/8/2010
Primary
Secondary
Concomitant
Middle Insomnia 8/12/2009 65 Female 162 lb 9/15/2010 Physician United States
Primary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 9/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea 4/21/2009 54 Female 299 lb 9/17/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/18/2010 57 Female 123 lb 9/22/2010 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 61 Female 279 lb 9/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 9/30/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/12/2010 Male 10/1/2010 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/7/2004 47 Female 10/5/2010 United States
Primary
Concomitant
Somnolence Hospitalization 7/11/2001 79 Male 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/31/2010 65 Male 10/7/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/13/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2009 66 Male 10/15/2010 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 8/1/2010 50 Male 200 lb 10/15/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/18/2010 57 Female 124 lb 10/18/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 2/18/2010 57 Female 124 lb 10/25/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 10/26/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Product Quality Issue 46 Female 10/27/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2010 83 Male 195 lb 10/29/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 12/9/2002 11/8/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/12/2010 United States
Primary
Secondary
Concomitant
Headache 8/10/2010 58 Male 176 lb 11/16/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/16/2010 United States
Primary
Secondary
Concomitant
Biliary Sepsis Hospitalization 10/24/2010 62 Male 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 49 Female 11/19/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/3/2010 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/1/2010 65 Female 195 lb 12/14/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 9/1/2010 49 Male 154 lb 12/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2010 50 Male 200 lb 12/17/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/30/2010 United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious Female 285 lb 12/21/2010 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death 56 Female 1/5/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 56 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Ligament Sprain Hospitalization 1/1/2005 63 Male 177 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 56 Female 1/12/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 56 Female 1/14/2011 Physician United States
Primary
Secondary
Asthenia Other Serious 7/1/2010 74 Female 1/21/2011 Physician United States
Primary
Concomitant
Eye Infection 8/13/2010 68 Female 205 lb 1/29/2011 Consumer United States
Primary
Concomitant
Oral Herpes 1/1/2010 72 Female 151 lb 1/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection 10/1/2010 62 Female 102 lb 1/30/2011 Other Health Professional United States
Primary
Concomitant
Poisoning Death 1/1/2009 56 Female 1/25/2011 Physician United States
Primary
Secondary
Death Death 1/1/2009 56 Female 1/27/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 56 Female 1/24/2011 Physician United States
Primary
Secondary
Bundle Branch Block Left Other Serious 62 Female 331 lb 1/26/2011 United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/1/2009 35 Female 2/15/2011 Other Health Professional United States
Primary
Concomitant
Abasia Other Serious Male 2/14/2011 Physician United States
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 6/26/2008 68 Female 2/21/2011 Consumer Canada
Primary
Concomitant
Headache Hospitalization 6/14/2010 77 Female 2/21/2011 Physician Canada
Primary
Concomitant
Multiple Drug Overdose Intentional Death 1/1/2009 56 Female 2/7/2011 Physician United States
Primary
Secondary
Hallucination Other Serious 3/15/2010 79 Male 185 lb 1/13/2011 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2005 63 Male 177 lb 2/28/2011 United States
Primary
Secondary
Concomitant
Constipation Other Serious 7/6/1998 47 Male 258 lb 3/2/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 6/26/2008 68 Female 3/3/2011 Consumer Canada
Primary
Concomitant
Death Death Female 3/4/2011 Physician United States
Primary
Secondary
Lung Consolidation Hospitalization 11/17/2010 53 Female 203 lb 2/22/2011 Other Health Professional Australia
Primary
Concomitant
Arteriosclerosis Hospitalization 6/1/2006 78 Male 200 lb 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 7/1/2009 35 Female 3/14/2011 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 63 Male 177 lb 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious Female 300 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data