Metformin combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 12/1/2002 Female 1/4/2006 France
Primary
Concomitant
Renal Failure Chronic Other Serious 5/25/2000 Female 1/4/2006 Australia
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/1999 62 Male 276 lb 1/6/2006 Physician Canada
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/1999 62 Male 276 lb 1/10/2006 Physician Canada
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Angioneurotic Oedema 10/9/2005 71 Male Pharmacist United States
Primary
Concomitant
Pruritus Hospitalization 11/20/2005 54 Male 194 lb 12/13/2005 Pharmacist United States
Primary
Concomitant
Skin Odour Abnormal Other Serious 8/1/2005 81 Male 2/24/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 6/1/2005 Male 263 lb 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 1/22/2006 78 Male 3/7/2006
Primary
Secondary
Concomitant
Fall Hospitalization 1/22/2006 78 Male 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/21/2005 Female 137 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased Other Serious 2/3/2006 68 Male 172 lb 3/15/2006 Physician Italy
Primary
Concomitant
Tachycardia Other Serious 11/28/2005 57 Female 3/22/2006 Physician Netherlands
Primary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 3/24/2006 Pharmacist United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 10/13/2005 76 Male 154 lb 10/13/2005 Other Health Professional United States
Primary
Concomitant
Herpes Zoster Hospitalization 2/18/2004 53 Male 3/27/2006 Physician United States
Primary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 3/20/2006 United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Weight Decreased 10/27/2005 57 Female 216 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Other Serious 8/30/2004 70 Male 4/5/2006 Physician Australia
Primary
Secondary
Concomitant
Death Other Serious Female 185 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Scar Hospitalization 2/18/2004 53 Male 254 lb 4/10/2006 Physician United States
Primary
Concomitant
Shoulder Pain Life Threatening 1/20/2006 58 Female 229 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 3/29/2006 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2001 61 Female 4/7/2006 Brazil
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/1998 58 Female 4/7/2006 Brazil
Primary
Concomitant
Cerebral Ischaemia Other Serious 1/1/2002 62 Female 4/7/2006 Brazil
Primary
Concomitant
Hyperkalaemia Hospitalization 3/22/2006 83 Male 148 lb 4/18/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2005 75 Female 197 lb 4/14/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2005 39 Male 4/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Cerebral Ischaemia Other Serious 1/1/2002 62 Female 4/19/2006 Brazil
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2001 61 Female 4/21/2006 Brazil
Primary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 8/1/2005 64 Male 2/17/2006 Physician United States
Primary
Concomitant
Syncope 2/6/2006 61 Male 5/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Shoulder Pain Life Threatening 1/20/2006 58 Female 229 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 11/22/2005 71 Male 194 lb 5/9/2006 Physician Belgium
Primary
Concomitant
Stridor Disability 2/24/2006 45 Female 5/8/2006 United States
Primary
Concomitant
Syncope Hospitalization 2/6/2006 61 Male 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control 45 Female 129 lb Physician United States
Primary
Concomitant
Pancytopenia Other Serious 4/12/2006 59 Female 218 lb 5/15/2006 Consumer Netherlands
Primary
Concomitant
Tachycardia Other Serious 5/8/2006 58 Female 143 lb 5/16/2006 Consumer Brazil
Primary
Secondary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 3/22/2006 83 Male 148 lb 5/22/2006 United Kingdom
Primary
Secondary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 5/19/2006 Physician United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/14/2005 64 Female 176 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Stomach Discomfort Hospitalization 1/1/2005 87 Male 134 lb 5/31/2006 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious Female 185 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Other Serious 11/1/2005 Male 200 lb 4/20/2006 Consumer United States
Primary
Concomitant
Sarcoma Other Serious 11/10/2004 72 Female 5/30/2006 Physician United States
Primary
Concomitant
Shoulder Pain Other Serious 11/10/2004 72 Female 6/7/2006 Physician United States
Primary
Concomitant
Nausea Hospitalization 5/27/2006 49 Male 260 lb 6/15/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/24/2006 Male 153 lb 6/27/2006 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/30/2004 70 Male 6/28/2006 Physician Australia
Primary
Secondary
Concomitant
Injection Site Bruising 1/1/2006 67 Female 249 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 2/22/2006 68 Male 290 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2004 77 Male 195 lb 6/27/2006 United States
Primary
Concomitant
Weight Decreased 1/1/2006 60 Female 235 lb 4/17/2006 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 6/14/2006 65 Male 7/10/2006 Pharmacist United Kingdom
Primary
Concomitant
Nausea Hospitalization 5/27/2006 49 Male 260 lb 6/27/2006 Physician United States
Primary
Concomitant
Confusional State Other Serious Female 185 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 4/9/2006 78 Male 154 lb 7/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Positron Emission Tomogram Abnormal Other Serious 11/10/2004 72 Female 6/30/2006 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 4/12/2006 59 Female 218 lb 7/19/2006 Consumer Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 5/6/2006 76 Male Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/12/2006 76 Male 7/14/2006 Other Health Professional New Zealand
Primary
Concomitant
Blood Glucose Increased 8/1/2005 51 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 78 Male 7/21/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 4/20/2006 52 Female 7/25/2006 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2006 59 Male Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 4/9/2006 78 Male 154 lb 7/28/2006 Other Health Professional France
Primary
Concomitant
Interacting
Lethargy Other Serious 5/17/2005 Female 137 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 2/13/2006 Female 185 lb 8/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 65 Male 8/8/2006 Physician New Zealand
Primary
Secondary
Hyperkalaemia Other Serious 4/3/2006 61 Male 8/22/2006 Pharmacist Australia
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 2/13/2006 Female 185 lb 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemic Coma Death 6/12/2006 49 Male 8/24/2006 United States
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 4/8/2006 78 Male 154 lb 9/5/2006 Other Health Professional France
Primary
Concomitant
Interacting
Therapeutic Response Delayed Life Threatening 3/27/2006 63 Male 174 lb 8/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Spinal Disorder Other Serious 7/4/2006 56 Female 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 4/12/2006 65 Female 194 lb 7/19/2006 Consumer United States
Primary
Concomitant
Sensory Loss Other Serious 1/1/2003 Female 10/6/2006 Consumer Spain
Primary
Concomitant
Ventricular Hypokinesia Other Serious 11/25/2005 67 Male 159 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 8/18/2006 70 Male 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 8/9/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 10/14/2006 56 Female 11/13/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/2/2005 58 Female 11/29/2006 Consumer Australia
Primary
Secondary
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 1/1/2003 Female 12/8/2006 Consumer Spain
Primary
Concomitant
Vomiting Other Serious 3/2/2005 58 Female 12/8/2006 Consumer Australia
Primary
Secondary
Cardiac Pacemaker Insertion Other Serious 61 Male 12/28/2006 United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 6/5/2006 63 Male 1/19/2007 Consumer Ireland
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Hospitalization 12/18/2006 70 Male 163 lb 1/22/2007 Consumer United States
Primary
Concomitant
Hyperkalaemia Other Serious 4/3/2006 61 Male 2/14/2007 Pharmacist Australia
Primary
Concomitant
Tremor 3/14/2006 51 Female 188 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Increased 9/8/2006 70 Male 216 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 57 Female 196 lb 10/16/2006 Consumer United States
Primary
Concomitant
Cardiac Pacemaker Insertion Other Serious Male 3/5/2007 Physician United Kingdom
Primary
Concomitant
Procedural Pain Other Serious 11/25/2006 74 Female 259 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/20/2007 64 Male 163 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 77 Male 4/2/2007 Physician Sweden
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/7/2007 53 Female 327 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 9/1/2006 Male 187 lb 4/12/2007 Physician France
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2006 52 Male 4/12/2007 Physician Spain
Primary
Concomitant
Myalgia 2/1/2007 71 Female 174 lb 5/17/2007 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 8/14/2006 66 Female 6/25/2007 United States
Primary
Concomitant
Death Disability 3/1/2007 80 Female 90 lb 7/9/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/4/2007 73 Female 119 lb 7/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematochezia 8/11/2007 50 Male 389 lb 8/28/2007 Pharmacist United States
Primary
Concomitant
Fungal Infection Other Serious 11/27/2006 Female 200 lb 9/7/2007 Consumer Canada
Primary
Concomitant
Myalgia 9/1/2007 64 Female 207 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/10/2007 Male 9/14/2007 Pharmacist United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Speech Disorder Other Serious 12/1/2006 69 Female 198 lb 9/24/2007 Consumer United Kingdom
Primary
Concomitant
Myalgia 2/1/2007 70 Female 174 lb 8/16/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 10/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 51 Male 9/25/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 10/4/2007 58 Male 261 lb 10/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Erysipelas Hospitalization 10/3/2007 63 Female 10/16/2007 Physician Germany
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/23/2007 83 Male 10/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2007 48 Male 328 lb 10/16/2007 Physician United Kingdom
Primary
Concomitant
Headache 80 Male 10/24/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 8/7/2007 57 Male 257 lb 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance 6/8/2006 69 Male 10/25/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 42 Female 10/26/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 9/1/2007 71 Male 10/26/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/13/2006 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 364 lb 11/5/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 10/29/2007 81 Female 11/12/2007 Consumer Chile
Primary
Concomitant
Acute Promyelocytic Leukaemia Hospitalization 9/1/2004 54 Male 262 lb 12/26/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/1/2007 Female 250 lb 1/10/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/8/2005 71 Female 205 lb 2/20/2008 Physician Brazil
Primary
Concomitant
Device Occlusion Hospitalization 9/17/2007 61 Female 3/3/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/8/2005 71 Female 205 lb 3/7/2008 Physician Brazil
Primary
Concomitant
Nausea 11/21/2007 67 Female 2/15/2008 Physician United States
Primary
Concomitant
Nervous System Disorder Hospitalization 11/17/2007 Male 128 lb 3/13/2008 Consumer United Kingdom
Primary
Concomitant
Wound Infection 1/1/2007 76 Female 192 lb 3/13/2008 Physician Netherlands
Primary
Concomitant
Myeloid Leukaemia Other Serious Male 3/17/2008 Physician France
Primary
Concomitant
Renal Failure Life Threatening 6/5/2006 63 Male 3/24/2008 Consumer Ireland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Angioedema Other Serious Female 6/18/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 38 Male 198 lb 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data