Metformin combined with Novorapid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Life Threatening 7/30/2005 47 Male 203 lb 4/4/2006 Physician Canada
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 7/30/2005 53 Male 203 lb 4/19/2006 Physician Canada
Primary
Secondary
Concomitant
Skin Exfoliation Disability 8/24/2004 72 Female 188 lb 5/3/2006 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Other Serious 4/25/2005 61 Female 132 lb 7/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/12/2006 59 Male 293 lb 12/5/2006 Physician United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 11/30/2006 79 Male 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 11/30/2006 79 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 7/6/2007 51 Female 197 lb 9/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Other Serious 7/3/2007 76 Female 9/7/2007 Consumer Australia
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 7/26/2007 Female 9/28/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 64 Male 12/31/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cardiac Arrest Death 8/1/2008 Female 8/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 12/19/2008 22 Male 287 lb 2/3/2009 Physician Finland
Primary
Concomitant
Resuscitation Other Serious 1/12/2009 Male 2/3/2009 Physician Canada
Primary
Concomitant
Nausea Hospitalization 2/1/2009 65 Male 2/25/2009 Physician Sweden
Primary
Concomitant
Sepsis Hospitalization 12/30/2008 67 5/8/2009 Physician Norway
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 3/5/2009 69 6/8/2009 Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2009 59 Male 231 lb 8/12/2009 Physician United Kingdom
Primary
Concomitant
Polychondritis Hospitalization 4/14/2009 59 Female 1/25/2010 Other Health Professional Canada
Primary
Concomitant
Hyperglycaemia Hospitalization 12/11/2009 67 Female 4/28/2010 Lawyer Brazil
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 4/8/2010 69 Male 4/30/2010 Physician Australia
Primary
Concomitant
Productive Cough Other Serious 4/22/2009 51 Female 227 lb 5/6/2010 United Kingdom
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 9/1/2008 65 Female 229 lb 6/7/2010 Physician Canada
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 2/12/2010 76 Male 198 lb 6/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 4/1/2010 38 Female 331 lb 6/17/2010 Pharmacist Sweden
Primary
Concomitant
Visual Impairment Other Serious Female 141 lb 6/17/2010 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Other Serious 54 Female 205 lb 6/18/2010 Other Health Professional Canada
Primary
Concomitant
Throat Cancer Other Serious 6/1/2008 64 Female 140 lb 7/22/2010 Physician Australia
Primary
Secondary
Concomitant
Tremor Other Serious 1/30/2000 Female 137 lb 8/23/2010 Consumer Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 8/25/2010 Physician New Zealand
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 6/1/2008 64 Female 140 lb 8/27/2010 Physician Australia
Primary
Secondary
Concomitant
Arrhythmia Hospitalization Male 9/1/2010 Other Health Professional Sweden
Primary
Concomitant
Respiratory Failure Other Serious 7/20/2010 63 Male 9/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 4 lb 9/10/2010 Physician Australia
Primary
Secondary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Death 53 Female 9/23/2010 Consumer Australia
Primary
Secondary
Arrhythmia Hospitalization Male 9/30/2010 Other Health Professional Sweden
Primary
Concomitant
Pruritus Death 7/22/2004 68 Male 187 lb 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 10/14/2010 Physician New Zealand
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 6/1/2010 52 Male 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 69 Male 10/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Other Serious 7/20/2010 63 Male 10/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Death 1/22/2010 58 Female 245 lb 10/28/2010 Physician Greece
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 69 Male 10/28/2010 Consumer United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 10/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Disability 8/11/2010 52 Male 252 lb 10/28/2010 Physician New Zealand
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 9/8/2010 54 Male 11/1/2010 Physician Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 11/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/1/2010 53 Female 11/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/1/2010 53 Female 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 10/1/2010 63 Female 209 lb 11/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2010 53 Female 11/10/2010 Physician Denmark
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/1/2008 11/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 9/15/2009 49 Male 211 lb 12/6/2010 Physician Ireland
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization Female 12/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 3/1/2010 36 Female 247 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 10/1/2010 63 Female 209 lb 12/17/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 1/1/2010 67 Male 255 lb 1/12/2011 Physician Australia
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 11/16/2010 65 Female 1/27/2011 Pharmacist Netherlands
Primary
Concomitant
Interacting
Acute Abdomen Hospitalization 12/12/2010 66 Female 216 lb 1/31/2011 United Kingdom
Primary
Concomitant
Acute Abdomen Hospitalization 12/12/2010 66 Female 216 lb 2/2/2011 Physician United Kingdom
Primary
Concomitant
Abortion Spontaneous Hospitalization 4/12/2010 26 Female 236 lb 2/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/18/2011 Consumer United Kingdom
Primary
Concomitant
Colitis Hospitalization 12/12/2010 66 Female 216 lb 2/22/2011 Consumer United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 12/12/2010 66 Female 216 lb 3/14/2011 Consumer Germany
Primary
Concomitant
Hypoacusis Other Serious Male 194 lb 3/14/2011 Consumer Brazil
Primary
Concomitant
Arrhythmia Death 1/7/2011 79 Male 4/7/2011 Physician Netherlands
Primary
Concomitant
Herpes Zoster Hospitalization 3/31/2011 31 Female 4/13/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/28/2011 71 Female 187 lb 4/14/2011 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/31/2011 31 Female 4/27/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/31/2011 31 Female 4/29/2011 Pharmacist Denmark
Primary
Secondary
Concomitant
Colitis Other Serious 12/12/2010 66 Female 216 lb 7/21/2011 Consumer Germany
Primary
Concomitant
Hypoglycaemia Other Serious 7/19/2011 50 Male 185 lb 8/2/2011 Physician Netherlands
Primary
Concomitant
Cardiac Arrest Other Serious 6/1/2010 52 Male 8/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 303 lb 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 1/1/2011 60 Male 238 lb 9/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 9/2/2011 68 Male 10/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 4/1/2010 54 Male 10/28/2011 Consumer Australia
Primary
Concomitant
Intracranial Tumour Haemorrhage Hospitalization 11/12/2011 56 Male 168 lb 12/23/2011 Physician Spain
Primary
Secondary
Concomitant
Rash Papular Other Serious 12/10/2011 47 Male 1/10/2012 Other Health Professional Denmark
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/9/2012 65 Female 295 lb 2/28/2012 Physician Netherlands
Primary
Secondary
Concomitant
Tachycardia Other Serious 4/19/2012 61 Female 7/16/2012 Other Health Professional France
Primary
Secondary
Concomitant
Dizziness Hospitalization 5/25/2012 78 Female 7/18/2012 Physician Sweden
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 1/1/2012 69 Female 8/23/2012 Consumer New Zealand
Primary
Concomitant
Blood Glucose Decreased Hospitalization 1/1/2005 62 Female 132 lb 8/27/2012 Consumer Brazil
Primary
Secondary
Concomitant
Paralysis Hospitalization 12/11/2009 67 Female 159 lb 10/22/2012 Consumer Br
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/20/2010 53 Male 252 lb 1/21/2013 Physician Nz
Primary
Concomitant
Angina Unstable Hospitalization 8/7/2010 53 Male 252 lb 1/21/2013 Physician Nz
Primary
Concomitant
Suicidal Ideation Disability 8/11/2010 53 Male 252 lb 3/29/2013 Physician Nz
Primary
Concomitant
Thirst Hospitalization 12/20/2011 87 Female 132 lb 10/1/2012 Physician Dk
Primary
Concomitant
Sudden Cardiac Death Hospitalization 7/2/2011 60 Male 9/12/2012 Physician Se
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 3/2012 74 Male 8/29/2012 Consumer Ca
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 3/2012 74 Male 8/31/2012 Consumer Ca
Primary
Secondary
Concomitant
Hyponatraemia 76 Male 9/6/2012 Au
Primary
Secondary
Vitreous Haemorrhage Other Serious 9/10/2012 63 Male 185 lb 10/11/2012 Other Health Professional Gb
Primary
Concomitant
Transient Ischaemic Attack Disability 5/25/2006 75 Female 140 lb 1/2/2013 Consumer Ca
Primary
Secondary
Concomitant
Shock Other Serious 9/23/2012 73 Female 165 lb 10/9/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 62 Female 10/10/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 68 Male 10/10/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Shock Other Serious 9/23/2012 73 Female 168 lb 10/10/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Shock Other Serious 9/23/2012 73 Female 168 lb 10/12/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Shock Other Serious 9/23/2012 73 Female 168 lb 10/16/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Premature Baby Other Serious 2/10/2010 10/16/2012 Other Health Professional De
Primary
Secondary
Concomitant
Vomiting Other Serious 9/20/2012 Male 12/26/2012 Consumer De
Primary
Concomitant
Shock Other Serious 73 Female 168 lb 10/13/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Hellp Syndrome Other Serious 31 Female 331 lb 10/23/2012 Physician De
Primary
Secondary
Patent Ductus Arteriosus Congenital Anomaly 2/10/2010 Female 10/23/2012 Physician De
Primary
Secondary
Concomitant
Shock Other Serious 9/23/2012 73 Female 76 lb 10/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Shock Other Serious 9/24/2012 73 Female 10/18/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Congenital Anomaly 2/10/2010 Female 4 lb 10/25/2012 Other Health Professional De
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Congenital Anomaly 2/10/2010 Female 4 lb 10/26/2012 Physician De
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/31/2012 74 Female 191 lb 10/25/2012 Other Health Professional Au
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 12/2/2011 Male 196 lb 2/26/2013 Physician Gb
Primary
Concomitant
Hellp Syndrome Other Serious 2/10/2010 31 Female 10/26/2012 Physician De
Primary
Secondary
Concomitant
Transposition Of The Great Vessels Life Threatening 2009 Female 4 lb 11/15/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Hellp Syndrome Hospitalization 31 Female 11/12/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Premature Delivery Hospitalization 7/9/2009 31 Female 11/14/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization Female 4 lb 11/14/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Pyrexia Death 7/9/2012 76 Male 11/7/2012 Physician Gb
Primary
Concomitant
Pregnancy Congenital Anomaly 7/9/2009 11/19/2012 Physician Dk
Primary
Secondary
Concomitant
Neck Mass Hospitalization 66 Male 293 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Pregnancy Hospitalization 7/9/2009 31 Female 11/20/2012 Other Health Professional Dk
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 2/10/2010 31 Female 331 lb 11/12/2012 Physician Dk
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 2/10/2010 31 Female 331 lb 11/19/2012 Physician Dk
Primary
Secondary
Concomitant
Urine Output Decreased Congenital Anomaly 2/10/2010 Female 4 lb 11/20/2012 Physician Dk
Primary
Secondary
Concomitant
Pregnancy Hospitalization 7/9/2009 NotSpecified 3/25/2013 Physician Dk
Primary
Secondary
Concomitant
Pregnancy Hospitalization 7/9/2009 31 Female 3/24/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/18/2012 59 Male 161 lb 1/21/2013 Physician Ug
Primary
Secondary
Concomitant
Syncope Other Serious 11/2012 76 Female 11/29/2012 Consumer Co
Primary
Concomitant
Renal Failure Acute Hospitalization 10/30/2012 75 Male 179 lb 12/4/2012 Other Health Professional Gb
Primary
Concomitant
Weight Increased Hospitalization 10/15/2007 59 Female 170 lb 12/19/2012 Consumer Ca
Primary
Concomitant
Cellulitis Hospitalization Female 12/21/2012 Physician Au
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 11/29/2012 67 Female 2/25/2013 Consumer Gb
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 62 Female 1/14/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 64 Male 1/14/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Jaundice Hospitalization 11/12/2012 75 Female 3/22/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 11/29/2012 67 Female 2/28/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Acute Death 12/17/2012 79 Female 163 lb 2/28/2013 Other Health Professional De
Primary
Concomitant
Renal Failure Acute Death 12/17/2012 79 Female 163 lb 2/21/2013 Physician De
Primary
Concomitant
Loss Of Consciousness Hospitalization 11/29/2012 67 Female 2/11/2013 Consumer Gb
Primary
Secondary
Concomitant
Palpitations Other Serious 7/7/2012 59 Female 203 lb 1/21/2013 Consumer Gb
Primary
Secondary
Sudden Cardiac Death Hospitalization 7/2/2011 60 Male 9/10/2012 Physician Se
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 2/18/2012 71 Female 119 lb 11/6/2012 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data