Metformin combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 1/17/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 8/1/2003 48 Male 196 lb 1/23/2006 Physician United States
Primary
Concomitant
Pulmonary Hypertension Death 10/19/2005 Male 1/31/2006 United States
Primary
Concomitant
Skin Discolouration Other Serious 12/12/2005 Female 126 lb 1/31/2006 Physician United States
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 53 Male 300 lb 2/15/2006 Lawyer United States
Primary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/2/2003 48 Male 196 lb 2/17/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 2/21/2006 Physician United States
Primary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 8/20/2001 64 Female 121 lb 2/24/2006 Lawyer United States
Primary
Concomitant
Urticaria 11/15/2005 45 Male 2/27/2006 Consumer United States
Primary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 1/1/2001 68 Female 240 lb 3/1/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/2/2003 48 Male 196 lb 3/3/2006 Physician United States
Primary
Concomitant
Catheter Related Complication Other Serious 3/3/2004 62 Male 209 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/22/2006 Physician United States
Primary
Concomitant
Asthenia Required Intervention 3/10/2006 75 Female 3/12/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 10/13/2005 76 Male 154 lb 10/13/2005 Other Health Professional United States
Primary
Concomitant
Ventricular Dyskinesia Hospitalization 9/1/2001 71 Male 276 lb 3/28/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 3/4/2003 66 Female 238 lb 3/29/2006 Physician United States
Primary
Concomitant
Overdose Hospitalization 3/1/2003 60 Male 231 lb 3/30/2006 Lawyer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/4/2004 42 Male 274 lb 3/28/2006 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2004 71 Female 3/28/2006 Physician Czech Republic
Primary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 4/2/2006 72 Female 157 lb 4/5/2006 Pharmacist United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
Medication Error Disability 3/1/2005 50 Male 2/21/2006 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 7/30/2003 66 Female 238 lb 4/13/2006 Physician United States
Primary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Depression Hospitalization 11/20/2001 82 Male 134 lb 4/20/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2004 78 Male 4/21/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/2/2003 48 Male 196 lb 4/26/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2000 64 Female 121 lb 4/28/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 4/25/2006 Poland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 11/3/2001 64 Male 181 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2001 71 Male 276 lb 5/4/2006 Physician United States
Primary
Concomitant
Syncope 2/6/2006 61 Male 5/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/21/2006 60 Female 172 lb 5/22/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 62 Male 223 lb 4/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability Female 6/7/2006 Physician Canada
Primary
Concomitant
Blood Glucose Increased 6/1/2005 66 Female 7/21/2006 Consumer United States
Primary
Concomitant
Rash 5/29/2005 67 Female 7/21/2006 Consumer United States
Primary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Triglycerides Increased 8/1/2005 Male 7/21/2006 Consumer United States
Primary
Concomitant
Visual Disturbance 5/1/2005 Female 7/21/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 4/1/2006 66 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2006 54 Female 240 lb 8/14/2006 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 9/1/2006 Female 179 lb 9/22/2006 Consumer United States
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Vomiting Other Serious 6/1/2006 57 Male 9/25/2006 United States
Primary
Concomitant
Vomiting Hospitalization 10/23/2006 74 Male 190 lb 11/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Hospitalization 10/18/2006 72 Male 11/21/2006 Consumer United States
Primary
Concomitant
Hypokalaemia Other Serious 10/6/2003 74 Female 11/22/2006 United States
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 2/1/2007 58 Female 183 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/22/2007 58 Male 212 lb 3/26/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/22/2007 58 Male 212 lb 5/9/2007 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 73 Female 9/24/2007 Pharmacist United States
Primary
Concomitant
Interacting
Drug Ineffective 6/13/2007 Female 8/16/2007 United States
Primary
Concomitant
Weight Increased Hospitalization 10/4/2007 58 Male 261 lb 10/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 70 Female 175 lb 10/13/2007 Consumer Germany
Primary
Concomitant
Radius Fracture Other Serious Female 179 lb 10/12/2007 Physician Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2006 63 Male 10/15/2007 United States
Primary
Concomitant
Vomiting Required Intervention 10/10/2007 59 Female 201 lb 10/18/2007 Consumer United States
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Pharmaceutical Product Complaint 5/15/2007 67 Male 10/26/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 9/1/2007 71 Male 10/26/2007 Consumer United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 12/1/2007 78 Male 2/8/2008 Consumer United States
Primary
Concomitant
Fall Other Serious 4/3/2008 57 Male 260 lb 5/30/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/1/2008 Female 6/5/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 6/6/2008 Male 194 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 12/31/2007 55 Female 6/30/2008 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 72 Male 7/2/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/8/2008 Male 190 lb 7/13/2008 Physician Sweden
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 184 lb 7/8/2008 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2008 Male 7/8/2008 Consumer United States
Primary
Concomitant
Death Death 50 Female 8/22/2008 Pharmacist Canada
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 Female 160 lb 8/22/2008 United States
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2008 Male 220 lb 8/22/2008 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Upper Respiratory Tract Infection 2/1/2008 57 Male 174 lb 8/15/2008 Physician United States
Primary
Concomitant
Hypotension Hospitalization 9/3/2008 Female 9/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/11/2008 Consumer United States
Primary
Concomitant
Death Death 12/31/2008 Other Health Professional Colombia
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 Female 162 lb 12/24/2008 Consumer United States
Primary
Concomitant
Drug Toxicity Death 45 Male 1/12/2009 Physician United States
Primary
Secondary
Tachycardia Hospitalization 1/7/2009 Female 167 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Myalgia Other Serious 4/15/2008 77 Male 150 lb 1/22/2009 Physician United States
Primary
Concomitant
Lumbar Radiculopathy Hospitalization 11/12/2008 Male 198 lb 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Haematuria Hospitalization 12/31/2008 58 Female 1/19/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 55 Male 226 lb 1/30/2009 Lawyer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 55 Female 115 lb 1/29/2009 Consumer Mexico
Primary
Concomitant
Death Death 2/5/2009 Other Health Professional Colombia
Primary
Secondary
Concomitant
Intervertebral Disc Displacement Hospitalization 8/26/2008 47 Female 202 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Death 11/12/2008 Male 200 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 2/19/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 4/15/2008 77 Male 150 lb 2/23/2009 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 2/17/2003 Male 297 lb 2/24/2009 United States
Primary
Concomitant
Wound Treatment Other Serious 2/17/2003 Male 297 lb 2/24/2009 United States
Primary
Concomitant
Headache Female 2/24/2009 United States
Primary
Concomitant
Blood Glucose Increased 11/27/2008 Female 2/24/2009 United States
Primary
Concomitant
Constipation Male 2/24/2009 United States
Primary
Concomitant
Myalgia Male 2/24/2009 United States
Primary
Concomitant
Epistaxis Other Serious 5/22/2008 58 Male 2/25/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 2/1/2009 65 Male 2/25/2009 Physician Sweden
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/4/2009 74 Male 196 lb 2/23/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 2/21/2009 Male 153 lb 3/9/2009 Consumer United States
Primary
Concomitant
Malignant Melanoma Death 5/1/2008 Male 350 lb 3/11/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/16/2009 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/12/2009 Other Health Professional Sweden
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/20/2009 United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/31/2008 79 Male 240 lb 2/26/2009 Pharmacist United States
Primary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 3/27/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/27/2001 38 Female 179 lb 3/27/2009 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 3/14/2009 Male 159 lb 4/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 1/1/2007 Male 4/10/2009 Other Health Professional New Zealand
Primary
Concomitant
Hypotension Hospitalization 3/14/2009 Male 159 lb 4/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/14/2009 Male 159 lb 5/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 1/1/2009 Male 210 lb 6/1/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/5/2009 69 6/8/2009 Netherlands
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2006 Male 165 lb 6/26/2009 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 1/1/2009 Male 210 lb 7/7/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 210 lb 7/29/2009 Consumer United States
Primary
Concomitant
Colitis Microscopic Other Serious 59 Male 7/28/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 9/1/2008 Female 220 lb 7/31/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2006 Male 165 lb 8/3/2009 Consumer United States
Primary
Secondary
Concomitant
Social Problem Death 82 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 3/14/2009 Male 159 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious Female 325 lb 7/29/2009 Consumer United States
Primary
Concomitant
Renal Disorder Death 67 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 242 lb 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/1/2006 Female 165 lb 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/10/2009 United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/10/2009 United States
Primary
Concomitant
Surgery Death Female 8/4/2009 United States
Primary
Concomitant
Gastrointestinal Ulcer 10/10/2007 Male 162 lb 8/19/2009 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Due To General Medical Condition, Insomnia Type 6/1/2009 68 Female 8/19/2009 Consumer
Primary
Concomitant
Drug Ineffective 7/23/2009 Male 8/19/2009 Consumer
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/3/2006 65 Male 213 lb 8/20/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2001 45 Male 8/20/2009 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Male 270 lb 8/21/2009 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Female 8/21/2009 United States
Primary
Concomitant
Rash 8/1/2007 Male 8/21/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 8/21/2009 United States
Primary
Concomitant

Drug Data