Metformin combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Life Threatening 4/13/2005 Male 1/9/2006 Physician Germany
Primary
Secondary
Concomitant
Epistaxis Hospitalization 6/16/2005 64 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/23/2006 67 Male 188 lb 3/3/2006 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/10/2005 71 Male 250 lb 12/27/2005 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 53 Male 3/20/2006 Consumer Canada
Primary
Secondary
Faeces Discoloured 11/7/2005 54 Female 255 lb 1/20/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 10/1/2005 41 Male 389 lb 1/20/2006 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 3/30/2006 5/3/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/23/2006 70 Female 4/21/2006 Norway
Primary
Secondary
Concomitant
Serum Ferritin Decreased Other Serious 10/6/2005 72 Female 138 lb 5/5/2006 Physician Canada
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/1990 82 Male 5/1/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/28/2005 76 Male 200 lb 2/2/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 10/1/2005 79 Female 170 lb 4/20/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 8/1/1999 62 Male 275 lb 6/6/2006 Lawyer United States
Primary
Concomitant
Neck Pain Hospitalization 5/23/2006 46 Male 6/16/2006 Physician Switzerland
Primary
Concomitant
Oedema Peripheral Hospitalization 3/21/2006 60 Female 172 lb 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 4/1/2006 80 Male 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Middle Insomnia 2/28/2006 88 Male 152 lb 7/12/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 Male 210 lb 9/11/2006 Physician United States
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 9/22/2006
Primary
Concomitant
Headache 5/18/2006 76 Female 140 lb 8/23/2006 Physician United States
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/14/2006
Primary
Concomitant
Pneumonia Hospitalization 11/1/2006 58 Male 188 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Poisoning Death 58 11/10/2006 Physician United States
Primary
Secondary
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/2/2005 58 Female 11/29/2006 Consumer Australia
Primary
Secondary
Poisoning Death 58 11/16/2006 Physician United States
Primary
Secondary
Flushing Other Serious 11/1/2006 56 Male 182 lb 11/17/2006 United States
Primary
Concomitant
Skin Cancer Other Serious 3/1/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Kidney Infection 8/1/2005 41 Male 12/8/2006 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/26/2006 Female 12/8/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/2/2005 58 Female 12/8/2006 Consumer Australia
Primary
Secondary
Weight Increased Other Serious 5/1/2006 66 Male 153 lb 12/18/2006 Pharmacist Australia
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2006 75 Male 170 lb 12/19/2006 Physician Germany
Primary
Secondary
Concomitant
Carotid Artery Stenosis Hospitalization 9/21/2006 56 Male 225 lb 12/20/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/29/2006 60 Female 180 lb 12/22/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/10/2006 50 Female 12/28/2006 Physician Hong Kong
Primary
Secondary
Concomitant
Insomnia 1/1/2006 59 Female 10/11/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/23/2006 67 Male 222 lb 7/25/2006 Pharmacist United States
Primary
Concomitant
Ketoacidosis Other Serious 1/1/2000 49 Male 148 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/13/2007 Male 1/25/2007 Pharmacist Canada
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 198 lb 3/19/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 10/19/2006 65 Female 4/23/2007 United States
Primary
Secondary
Concomitant
Drug Ineffective 2/23/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Nasopharyngitis 5/1/2007 65 Male 7/11/2007 Consumer United States
Primary
Concomitant
Hallucination Other Serious 4/4/2006 62 Female 8/30/2007 Consumer United States
Primary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 Female 125 lb 9/21/2007 Physician United States
Primary
Concomitant
Interacting
Headache 2/15/2007 51 Male 280 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 7/15/2007 63 Male 234 lb 10/26/2007 Physician Sweden
Primary
Concomitant
Hyperhidrosis Hospitalization 11/1/2006 Male 1/15/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2007 Male 3/14/2008 Physician United States
Primary
Concomitant
Application Site Rash 1/1/2008 66 Female 3/24/2008 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/13/2005 53 Female 5/8/2008 Lawyer United States
Primary
Concomitant
Yellow Skin Other Serious 63 Male 185 lb 6/17/2008 United States
Primary
Concomitant
Renal Failure Life Threatening 5/24/2008 Female 7/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Hospitalization 2/1/2008 71 Male 159 lb 7/15/2008 Other Health Professional Germany
Primary
Concomitant
Malaise Other Serious 1/1/2007 Male 7/16/2008 Consumer United States
Primary
Concomitant
Interacting
Scab Hospitalization 8/15/1997 Female 172 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/1/2008 70 Male 131 lb 8/26/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/3/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/27/2000 44 Female 224 lb 9/10/2008 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/10/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/16/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/12/2008 50 Female 245 lb 10/20/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 9/9/2008 50 Female 218 lb 11/24/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 9/9/2008 50 Female 218 lb 12/2/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 9/1/2008 50 Female 245 lb 12/12/2008 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Death 11/30/2008 69 Female 205 lb 12/31/2008 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 66 Male 2/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/30/2008 69 Female 205 lb 2/11/2009 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 12/23/2008 2/17/2009 Germany
Primary
Secondary
Concomitant
Somnolence 4/1/2008 78 Female 3/4/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 150 lb 3/4/2009 Consumer United States
Primary
Concomitant
Sleep Disorder Hospitalization 12/16/2008 56 Female 3/12/2009 Germany
Primary
Concomitant
Drug Ineffective 10/29/2008 79 Male 190 lb 3/29/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/5/2009 70 Male 209 lb 5/1/2009 Other Health Professional Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/5/2009 70 Male 209 lb 5/4/2009 Other Health Professional Germany
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 4/29/2005 61 Male 241 lb 6/1/2009 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 75 Female 5/27/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Death 71 Male 5/28/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/6/2009 65 Male 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/10/2009 Ireland
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 5/30/2009 Consumer United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1995 40 Male 193 lb 6/11/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 220 lb 6/4/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 59 Female 214 lb 6/4/2009 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 3/5/2005 Female 6/24/2009 Consumer United Kingdom
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/24/2009 Ireland
Primary
Concomitant
Torsade De Pointes Other Serious 72 Female 6/25/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Febrile Neutropenia Hospitalization 6/11/2009 Female 6/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Death 4/9/2008 Male 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 Male 229 lb 6/30/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/11/2009 Female 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 11/1/2006 58 Female 7/2/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/1/2004 59 Male 165 lb 7/2/2009 Other Health Professional United States
Primary
Concomitant
Diabetic Foot Other Serious 1/1/2004 45 Male 200 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Disability 9/1/2008 86 Female 7/30/2009 Physician Canada
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Thyroidectomy Hospitalization 8/1/2008 Female 8/5/2009 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 9/1/2008 86 Female 8/12/2009 Physician Canada
Primary
Concomitant
Vertigo Male 8/21/2009 United States
Primary
Concomitant
Nausea 10/1/2008 Female 200 lb 8/22/2009 United States
Primary
Concomitant
Urticaria 1/1/2005 60 Female 8/22/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/23/2008 80 8/25/2009 Physician Germany
Primary
Secondary
Concomitant
Cerebral Haemorrhage Required Intervention 7/25/2009 75 Female 131 lb 7/27/2009 United States
Primary
Concomitant
Muscle Rupture Hospitalization 69 Male 10/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Operative Haemorrhage Other Serious 9/16/2009 77 Male 10/5/2009 Colombia
Primary
Secondary
Concomitant
Syncope Other Serious 9/16/2009 77 Male 10/19/2009 Colombia
Primary
Secondary
Concomitant
Muscle Rupture Hospitalization 69 Male 11/16/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 10/12/2009 62 Female 290 lb 12/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/10/2009 56 Female 12/17/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 12/1/2009 Female 1/31/2010 Other Health Professional Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/10/2009 56 Female 2/18/2010 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 12/21/2008 49 Male 385 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 163 lb 4/5/2010 Other Health Professional United States
Primary
Concomitant
Porphyria Acute Other Serious 3/1/2010 74 Male 5/7/2010 Other Health Professional Netherlands
Primary
Concomitant
Porphyria Acute Other Serious 3/1/2010 74 Male 5/7/2010 Other Health Professional Netherlands
Primary
Concomitant
Pneumonia Other Serious 12/1/2009 60 Female 198 lb 5/7/2010 Other Health Professional Canada
Primary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 5/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2009 68 Male 6/4/2010 Physician Germany
Primary
Secondary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 6/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 11/25/2008 76 Male 6/21/2010 Consumer Germany
Primary
Concomitant
Tendon Rupture Hospitalization Male 260 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 4/26/2008 63 Male 187 lb 7/22/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/31/2009 71 Female 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 75 Female 196 lb 7/23/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 4/27/2010 79 Female 7/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/12/2009 47 Male 8/11/2010 Other Health Professional Germany
Primary
Concomitant
Urosepsis Hospitalization 2/26/2010 67 Male 230 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/1/2010 60 Male 9/2/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/18/2010 60 Male 176 lb 9/3/2010 Physician Germany
Primary
Concomitant
Interacting
Tendon Rupture Hospitalization Male 260 lb 9/7/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/18/2010 60 Male 176 lb 9/10/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypertension Other Serious 9/9/2010 88 Female 9/22/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Other Serious 8/1/2010 57 Male 132 lb 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 7/3/2010 80 Male 152 lb 9/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2010 57 Male 132 lb 9/24/2010 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 7/3/2010 80 Male 152 lb 9/28/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Pathological Fracture Other Serious 4/27/2010 79 Female 10/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 4/27/2010 79 Female 10/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Rales Other Serious 10/11/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/12/2009 62 Female 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sluggishness Hospitalization 3/1/2010 60 Female 152 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 88 Female 137 lb 11/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 55 Female 176 lb 11/10/2010 Consumer Brazil
Primary
Secondary
Concomitant

Drug Data