Metformin Hydrochloride combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombosis Other Serious 11/23/2003 61 Male 256 lb 3/1/2006 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/10/2004 54 Female 220 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Sinus Bradycardia Other Serious 11/27/2003 61 Male 256 lb 3/30/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2003 52 Female 295 lb 4/21/2006 Physician United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 11/4/2003 54 Female 220 lb 5/2/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/25/2005 66 Male 5/19/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pruritus Other Serious 3/1/2005 73 Male 172 lb 5/25/2006 Physician Belgium
Primary
Concomitant
Ear Pain Hospitalization 12/1/2005 59 Female 238 lb 5/31/2006 Physician Australia
Primary
Secondary
Concomitant
Nervousness 1/20/2006 69 Female 137 lb 4/17/2006 Consumer United States
Primary
Concomitant
Sudden Death Death 5/4/2006 67 Male 243 lb 7/24/2006 Physician Austria
Primary
Concomitant
International Normalised Ratio Decreased 73 Female 139 lb 8/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/3/2005 45 Female 280 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2003 52 Female 295 lb 8/7/2006 Physician United States
Primary
Concomitant
Ear Pain Hospitalization 12/1/2005 59 Female 238 lb 8/11/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2005 45 Female 280 lb 8/30/2006 Physician United States
Primary
Secondary
Concomitant
Drug Interaction 1/1/2005 69 Female 165 lb 9/14/2006 Consumer United States
Primary
Secondary
Concomitant
Erysipelas Hospitalization 8/27/2006 63 Male 207 lb 9/27/2006 Physician Austria
Primary
Concomitant
Weight Decreased Required Intervention 11/1/2005 45 Female 244 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2006 63 Male 10/27/2006 Physician South Africa
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 64 Female 1/16/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/6/2006 59 Male 179 lb 4/26/2007 Physician United States
Primary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/31/2007 66 Female 11/26/2007 Physician Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 10/9/2007 59 Female 11/28/2007 Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/30/2007 66 Female 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 12/26/2007 68 Male 2/20/2008 Other Health Professional France
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 10/30/2007 66 Female 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 6/1/2006 56 Male 3/17/2008
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/30/2007 66 Female 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/1/2006 56 Male 3/20/2008 Physician Canada
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 6/1/2006 56 Male 4/14/2008 Physician United States
Primary
Secondary
Concomitant
Nephritis Allergic Other Serious 6/1/2006 56 Male 7/15/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/25/2005 66 Male 9/19/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 8/20/2008 43 Male 9/26/2008 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 5/28/2008 80 Female 10/1/2008 Other Health Professional Spain
Primary
Concomitant
Myocardial Infarction Hospitalization 3/25/2002 54 Male 226 lb 10/20/2008 Lawyer United States
Primary
Concomitant
Dry Mouth 3/1/2008 70 Male 10/20/2008 Consumer
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/20/2008 43 Male 10/28/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/20/2008 43 Male 10/31/2008 Physician Japan
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 12/3/2008 Physician Canada
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 12/4/2008 Physician Canada
Primary
Concomitant
Nausea 4/1/2007 65 Female 12/1/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 1/1/2008 Male 195 lb 12/24/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 1/1/2008 Male 195 lb 3/19/2009 Consumer United States
Primary
Concomitant
Death Death 48 Male 3/26/2009 Other Health Professional United States
Primary
Secondary
Lactic Acidosis Hospitalization 12/26/2007 68 Male 4/17/2009 Other Health Professional France
Primary
Secondary
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 5/1/2009 Physician Japan
Primary
Concomitant
Renal Cancer Death 5/1/2007 78 Male 143 lb 5/8/2009 Other Health Professional Austria
Primary
Concomitant
Peripheral Ischaemia 9/1/2008 78 Male 171 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Death Death 5/27/2009 Male 240 lb 6/3/2009 Physician United States
Primary
Concomitant
Dysphonia Hospitalization 1/1/2006 71 Male 228 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Trigger Finger 1/1/2008 Male 229 lb 6/11/2009 United States
Primary
Concomitant
Coronary Artery Disease Death 5/27/2009 Male 240 lb 6/10/2009 Physician United States
Primary
Concomitant
Knee Arthroplasty Other Serious 1/1/2006 Male 272 lb 6/10/2009 Consumer United States
Primary
Concomitant
Paraesthesia Female 6/15/2009 Consumer United States
Primary
Concomitant
Myalgia Other Serious 58 Male 6/29/2009 Other Health Professional Ireland
Primary
Concomitant
Myalgia Other Serious 58 Male 7/6/2009 Other Health Professional Ireland
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 48 Female 172 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/1/2009 Male 145 lb 8/31/2009 Consumer United States
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 9/16/2009 Other Health Professional France
Primary
Secondary
Ventricular Fibrillation Hospitalization 5/1/2004 46 Female 226 lb 9/30/2009 Pharmacist United States
Primary
Concomitant
Hiccups 8/24/2009 73 Male 216 lb 10/1/2009 Consumer United States
Primary
Concomitant
Syncope Hospitalization 56 Female 260 lb 9/25/2009 United States
Primary
Concomitant
Stress Other Serious 4/1/2008 Female 141 lb 10/12/2009 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 9/1/2009 Female 10/7/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2000 60 Male 230 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder Disability Female 236 lb 10/15/2009 United States
Primary
Concomitant
Wheezing Life Threatening 6/5/2009 64 163 lb 10/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 10/28/2009 Other Health Professional France
Primary
Secondary
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/4/2009 Other Health Professional France
Primary
Secondary
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 11/13/2009 Other Health Professional France
Primary
Secondary
Suicidal Ideation Other Serious 1/1/2009 Male 145 lb 12/1/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 204 lb 11/30/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/19/2009 79 Female 163 lb 1/6/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/1/2009 Female 12/23/2009 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 12/18/2009 79 Female 163 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Other Serious 5/1/2009 61 Female 250 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 2/18/2010 Other Health Professional France
Primary
Secondary
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 2/5/2010 United States
Primary
Concomitant
Nausea Hospitalization 76 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2010 76 Female 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 76 Female 3/2/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Underdose Hospitalization 6/1/2009 Male 3/2/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 70 Male 95 lb 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 65 Male 223 lb 3/11/2010 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 3/15/2010 Physician Canada
Primary
Concomitant
Pancreatitis Acute Other Serious 10/1/2007 Female 188 lb 3/16/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 70 Male 95 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Mass Other Serious 1/1/2007 Female 211 lb 3/18/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 2/17/2008 Male 250 lb 3/17/2010 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 Male 250 lb 3/17/2010 Physician United States
Primary
Concomitant
Somnolence Hospitalization 12/18/2005 Male 205 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2009 Female 3/26/2010 Consumer United States
Primary
Concomitant
Febrile Neutropenia Life Threatening 2/4/2010 Male 3/29/2010 Physician United States
Primary
Concomitant
Granulomatous Liver Disease Hospitalization 6/23/2009 68 Male 4/1/2010 Other Health Professional France
Primary
Secondary
Overdose Life Threatening 1/12/2010 78 Male 4/2/2010 Other Health Professional Spain
Primary
Secondary
Sinus Bradycardia Hospitalization Male 195 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia 5/7/2010 65 Female 186 lb 5/17/2010 United States
Primary
Concomitant
Cataract Operation Other Serious 9/1/2008 64 Female 5/18/2010 Other Health Professional United States
Primary
Concomitant
Nephropathy Hospitalization 57 Male 195 lb 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/18/2010 55 Female 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Epistaxis 4/4/2010 74 Female 220 lb 5/27/2010 Consumer United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Hospitalization 1/1/2010 78 Female 5/28/2010 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 10/1/2007 74 Female 6/7/2010 Physician Japan
Primary
Concomitant
Paraesthesia 1/1/2009 65 Male 145 lb 6/29/2010 Pharmacist United States
Primary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 7/2/2010 Physician United States
Primary
Concomitant
Dyspnoea Female 7/30/2010 Consumer United States
Primary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 8/6/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious Female 219 lb 9/10/2010 Physician United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 60 Female 9/17/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 7/10/2010 61 Female 10/5/2010 Physician United States
Primary
Secondary
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/1/2010 55 Male 198 lb 10/29/2010 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 5/1/2010 55 Male 198 lb 12/16/2010 Consumer Brazil
Primary
Concomitant
Jaundice Hospitalization 10/1/2010 83 Female 150 lb 1/21/2011 Other Health Professional Australia
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/16/2011 56 Female 2/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 1/1/2010 65 Female 2/21/2011 Pharmacist Australia
Primary
Concomitant
Dizziness Hospitalization 9/1/2010 72 Female 3/10/2011 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 1/1/2010 65 Female 3/15/2011 Other Health Professional Australia
Primary
Concomitant
Presyncope Other Serious 1/6/2011 76 Female 141 lb 4/7/2011 Other Health Professional Netherlands
Primary
Concomitant
Glaucoma 1/1/2004 59 Female 210 lb 5/2/2011 United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 9/4/2004 57 Female 230 lb 5/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 10/1/2009 65 Male 209 lb 5/10/2011 Physician Germany
Primary
Concomitant
Hepatic Steatosis Other Serious 10/1/2009 65 Male 209 lb 5/20/2011 Physician Germany
Primary
Concomitant
Renal Failure Other Serious Female 206 lb 6/7/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 4/23/2011 56 Female 7/1/2011 Other Health Professional France
Primary
Secondary
Rhabdomyolysis Life Threatening 4/23/2011 56 Female 7/5/2011 Other Health Professional France
Primary
Secondary
Angina Pectoris Life Threatening 6/1/2011 69 Female 150 lb 7/14/2011 Physician Japan
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 5/1/2006 69 Female 8/9/2011 Japan
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 12/31/2004 83 Female 209 lb 8/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 1/1/2000 60 Female 205 lb 8/29/2011 Consumer United States
Primary
Concomitant
Dizziness Other Serious 11/1/2010 67 Male 190 lb 9/15/2011 Consumer United States
Primary
Secondary
Concomitant
Insomnia Other Serious 11/1/2010 67 Male 190 lb 10/12/2011 United States
Primary
Secondary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Hallucination Other Serious 11/25/2011 58 Male 161 lb 12/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 9/29/2011 76 Male 1/18/2012 Consumer Germany
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 10/27/2011 67 Female 170 lb 11/16/2011 Pharmacist United States
Primary
Concomitant
Hypersensitivity Hospitalization 10/25/2011 58 Female 293 lb 1/20/2012 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2007 73 Male 172 lb 3/8/2012 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 1/1/2011 54 Female 260 lb 3/11/2012 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2011 73 Female 146 lb 3/19/2012 Physician United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 6/28/2011 53 Female 320 lb 3/19/2012 Other Health Professional United States
Primary
Concomitant
Amnesia Other Serious 8/20/2010 77 Male 3/19/2012 Physician United States
Primary
Concomitant
Bladder Transitional Cell Carcinoma Required Intervention 10/1/2011 75 Male 6/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/2/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/6/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Intervertebral Discitis Hospitalization 12/28/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 9/21/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data