Metformin Hydrochloride combined with Vitamin D

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lactic Acidosis Hospitalization 35 Male 10/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/1/2007 Female 11/12/2007 Physician United States
Primary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Thrombosis Hospitalization 7/1/2007 Female 229 lb 10/14/2008 Consumer United States
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2008 Male 203 lb 3/31/2009 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2008 64 Male 4/24/2009 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/2/2008 83 Female 6/2/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 37 Female 252 lb 6/5/2009 United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 6/11/2009 United States
Primary
Concomitant
Psoriasis 2/16/2009 Male 235 lb 6/11/2009 United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 178 lb 6/12/2009 Consumer United States
Primary
Concomitant
Anxiety 4/15/2009 Female 170 lb 6/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2008 Female 265 lb 6/12/2009 United States
Primary
Concomitant
Gastroenteritis Viral Hospitalization 4/21/2009 60 Male 207 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Nausea Disability 4/30/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 5/5/2009 Male 7/14/2009 Pharmacist Australia
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Tremor 5/25/2009 53 Female 136 lb 10/12/2009 United States
Primary
Concomitant
Asthma Other Serious 11/12/2009 Female 270 lb 12/1/2009 Physician United States
Primary
Concomitant
Product Quality Issue 9/14/2009 62 Female 1/4/2010 Consumer United States
Primary
Concomitant
Femur Fracture Other Serious 5/1/2009 61 Female 250 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2008 Female 1/15/2010 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 11/16/2009 Female 160 lb 1/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2010 77 Female 2/17/2010 Consumer Canada
Primary
Concomitant
Haemolysis Hospitalization 7/1/2008 68 Female 218 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Syndrome Other Serious 11/1/2008 Female 3/2/2010 Physician United States
Primary
Concomitant
Pulse Absent Other Serious 12/1/2009 Female 101 lb 3/3/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 1/1/2009 74 Female 3/1/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/1993 Female 3/9/2010 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious Female 3/2/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 11/16/2009 Female 160 lb 3/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 11/12/2009 Female 270 lb 3/22/2010 United States
Primary
Concomitant
Product Odour Abnormal Other Serious 1/1/2010 78 Female 179 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/1/2009 78 Female 5/10/2010 Consumer Australia
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2010 75 Male 250 lb 5/13/2010 United States
Primary
Concomitant
Vomiting Other Serious 4/8/2008 68 Male 5/14/2010 Lawyer United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 1/1/2009 66 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Nausea 1/26/2010 50 Female 4/19/2010 Consumer United States
Primary
Concomitant
Diarrhoea 3/31/2010 30 Female 5/17/2010 United States
Primary
Secondary
Concomitant
Pruritus 3/28/2010 67 Female 200 lb 5/17/2010 United States
Primary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2009 65 Male 170 lb 5/18/2010 Canada
Primary
Concomitant
Weight Increased 75 Female 5/18/2010 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/5/2010 50 Male 205 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 64 Female 169 lb 5/18/2010 Consumer United States
Primary
Concomitant
Vision Blurred 77 Female 5/20/2010 Consumer United States
Primary
Concomitant
Fatigue Other Serious 8/1/2009 89 Male 5/21/2010 Physician Canada
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2009 67 Female 184 lb 5/26/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 60 Female 6/23/2010 Consumer United States
Primary
Secondary
Renal Failure Acute Other Serious 2/16/2010 71 Male 7/5/2010 Physician United States
Primary
Concomitant
Sepsis Neonatal Hospitalization 5/27/2009 6 lb 9/27/2010 Other Health Professional United States
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prostatomegaly Other Serious 1/1/2010 73 Male 244 lb 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Prostatomegaly Other Serious 1/1/2010 Male 244 lb 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Lip Swelling 1/28/2011 63 Female 150 lb 2/14/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 1/2/2011 59 Female 3/18/2011 Consumer United States
Primary
Concomitant
Eye Irritation Other Serious 3/14/2011 70 Female 3/18/2011 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 1/20/2011 86 Female 141 lb 5/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Conjunctivitis 9/30/2010 59 Male 5/3/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/26/2011 55 Female 131 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Dry Eye Female 5/4/2011 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Increased 6/17/2011 59 Male 390 lb 6/21/2011 Consumer United States
Primary
Concomitant
Coronary Artery Disease Other Serious 12/16/2010 69 Male 269 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Nerve Degeneration Hospitalization 7/28/2010 62 Female 292 lb 7/21/2011 Other Health Professional United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 7/28/2010 62 Female 292 lb 7/26/2011 Other Health Professional United States
Primary
Concomitant
Paraesthesia 6/17/2011 59 Male 390 lb 7/24/2011 Consumer United States
Primary
Concomitant
Lung Infection Other Serious 1/1/2010 56 Male 247 lb 8/11/2011 Other Health Professional Brazil
Primary
Concomitant
Unresponsive To Stimuli Other Serious Male 8/19/2011 Consumer United States
Primary
Concomitant
Choking Sensation 1/1/2010 80 Male 8/20/2011 Consumer United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 3/10/2011 82 Male 172 lb 8/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Mass Other Serious 4/1/2011 66 Female 8/24/2011 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/1/2010 57 Female 278 lb 8/29/2011 Physician United States
Primary
Concomitant
Palpitations Hospitalization 7/18/2011 60 Male 9/14/2011 Consumer United States
Primary
Concomitant
Blister 7/10/2001 59 Female 10/7/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Disability 6/9/2011 65 Female 200 lb 10/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea 9/30/2010 59 Male 10/11/2011 Physician United States
Primary
Concomitant
Temporal Arteritis Other Serious 7/1/2011 73 Male 137 lb 10/12/2011 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2011 81 Male 10/5/2011 Other Health Professional United States
Primary
Concomitant
Arthralgia Other Serious Male 156 lb 10/11/2011 Physician United States
Primary
Concomitant
Mass Other Serious 4/1/2011 66 Female 10/14/2011 Physician United States
Primary
Concomitant
Neck Pain Hospitalization 6/13/2011 76 Female 10/12/2011 Consumer United States
Primary
Concomitant
Arthritis Other Serious Female 159 lb 11/28/2011 Consumer Brazil
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 12/2/2011 Physician United States
Primary
Concomitant
Osteoporosis Other Serious Female 1/20/2012 Consumer United States
Primary
Secondary
Alopecia Other Serious Female 1/20/2012 United States
Primary
Secondary
Death Death Male 1/23/2012 Physician United States
Primary
Concomitant
Drug Ineffective 12/14/2011 70 Male 265 lb 1/24/2012 Physician United States
Primary
Concomitant
Somnolence Other Serious 5/1/2011 37 Female 279 lb 1/24/2012 Consumer United States
Primary
Concomitant
Failure To Thrive Hospitalization 11/26/2011 69 Female 144 lb 2/10/2012 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 1/30/2012 71 Female 249 lb 2/9/2012 Physician United States
Primary
Concomitant
Abdominal Discomfort Hospitalization 12/5/2009 62 Female 148 lb 2/29/2012 Brazil
Primary
Secondary
Concomitant
Multiple Myeloma Death 11/9/2011 74 Female 3/8/2012 Physician United States
Primary
Concomitant
Syncope Hospitalization 3/27/2011 72 Female 3/9/2012 United States
Primary
Concomitant
Pruritus 2/1/2012 81 Female 3/9/2012 Consumer United States
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Other Serious Male 221 lb 3/16/2012 Consumer United States
Primary
Concomitant
Hepatitis B Other Serious 1/1/2008 53 Female 3/16/2012 Consumer United States
Primary
Concomitant
Dizziness 3/1/2012 64 Female 172 lb 3/21/2012 Consumer United States
Primary
Concomitant
Agitation Other Serious 3/1/2011 63 Female 172 lb 3/21/2012 Consumer United States
Primary
Concomitant
Irritability 3/1/2012 64 Female 172 lb 3/22/2012 Consumer United States
Primary
Concomitant
Drug Interaction Female 3/23/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Agitation Other Serious 3/1/2011 63 Female 172 lb 3/26/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/30/2012 71 Female 249 lb 3/28/2012 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 12/1/2011 55 Female 240 lb 4/27/2012 Consumer United States
Primary
Secondary
Aortic Stenosis Hospitalization 1/13/2012 81 Female 152 lb 5/22/2012 Consumer France
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/13/2012 81 Female 152 lb 6/7/2012 Consumer France
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization Male 234 lb 6/22/2012 Other Health Professional United States
Primary
Concomitant
Thyroid Cancer Other Serious 62 Female 7/3/2012 Physician United States
Primary
Concomitant
Injection Site Pain Other Serious 5/27/2012 61 Female 271 lb 7/5/2012 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 50 Female 6/26/2012 Physician Australia
Primary
Concomitant
Blood Creatinine Increased Other Serious 75 Female 11/5/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2011 66 Female 200 lb 7/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Gallbladder Disorder Other Serious 4/23/2012 65 Female 7/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 3/6/2012 58 Female 179 lb 7/13/2012 Physician Hungary
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2011 73 Female 7/14/2012 Consumer United States
Primary
Concomitant
Cardiac Arrest Life Threatening 11/27/2011 62 Male 254 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 7/9/2012 74 Female 7/17/2012 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2012 58 Female 7/17/2012 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 6/9/2011 66 Female 200 lb 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 6/29/2012 49 Female 182 lb 7/18/2012 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 6/29/2012 49 Female 182 lb 7/18/2012 Physician United States
Primary
Concomitant
Dehydration Other Serious 5/1/2012 50 Female 162 lb 7/19/2012 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/16/2010 69 Male 269 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Cough 12/19/2005 64 Female 168 lb 7/20/2012 United States
Primary
Secondary
Concomitant
Rash Generalised 7/1/2011 69 Female 200 lb 7/20/2012 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 1/1/2012 65 Male 7/25/2012 Physician Canada
Primary
Concomitant
Attention Deficit/hyperactivity Disorder 64 Female 138 lb 7/26/2012 United States
Primary
Concomitant
Medication Residue 7/1/2011 63 Male 7/27/2012 Pharmacist United States
Primary
Concomitant
Dementia Other Serious 68 Female 7/26/2012 Consumer United States
Primary
Concomitant
Nausea 6/1/2012 55 Female 7/30/2012 Consumer United States
Primary
Concomitant
Immunosuppression Disability 6/9/2011 66 Female 200 lb 7/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Hospitalization 4/5/2010 24 Female 7/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 6/29/2012 49 Female 182 lb 7/30/2012 Physician United States
Primary
Concomitant
Fatigue Other Serious 11/14/2011 69 Male 7/24/2012 Physician Canada
Primary
Concomitant
Respiratory Arrest Hospitalization 10/1/2009 82 Female 7/30/2012 Consumer United States
Primary
Concomitant
Platelet Count Decreased 1/1/2011 57 Male 7/30/2012 Consumer United States
Primary
Concomitant
Off Label Use 57 Male 260 lb 7/31/2012 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/31/2012 Physician United States
Primary
Concomitant
Hypertension Other Serious 4/1/2012 58 Female 246 lb 7/31/2012 Physician United States
Primary
Concomitant
Asthenia Other Serious 5/11/2012 91 Female 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Wheezing 5/30/2012 72 Male 165 lb 8/1/2012 United States
Primary
Concomitant
Visual Impairment Hospitalization 4/12/2012 70 Male 246 lb 5/4/2012 Pharmacist United States
Primary
Concomitant
Gangrene Hospitalization 4/11/2012 54 Male 270 lb 5/9/2012 Pharmacist United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 6/4/2012 65 Male 261 lb 6/11/2012 Pharmacist United States
Primary
Secondary
Concomitant
Angiotensin Converting Enzyme Decreased Other Serious 61 Male 8/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data