Metformin Hydrochloride combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 1/18/2006 Female 245 lb 2/9/2006 Consumer United States
Primary
Secondary
Concomitant
Cough Other Serious 1/31/2006 74 Male 256 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 3/1/2001 56 Female 245 lb 5/4/2006 Lawyer United States
Primary
Concomitant
Dyspnoea Other Serious 3/6/2006 75 Male 335 lb 5/12/2006 Consumer United States
Primary
Concomitant
Swelling 4/24/2006 Male 418 lb 6/30/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 3/6/2006 75 Male 335 lb 7/6/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Stool Analysis Abnormal 74 Female 7/18/2006 Other Health Professional United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/7/2006 77 Male 236 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 64 Female 1/16/2007 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 12/29/2006 54 Female 277 lb 4/26/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 1/1/2006 51 Female 226 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Nail Disorder Female 195 lb 9/12/2007 United States
Primary
Concomitant
Vomiting Other Serious 8/17/2007 43 Female 11/20/2007 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious 11/7/2007 Female 170 lb 11/21/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/2/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 49 Female 190 lb 10/10/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2007 Female 200 lb 10/8/2008 Physician United States
Primary
Concomitant
Thyroid Cancer Hospitalization 8/1/2008 Female 251 lb 10/22/2008 Consumer United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 10/2/2008 Female 10/22/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/29/2008 Female 198 lb 10/23/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2008 65 Female 182 lb 10/24/2008 United States
Primary
Concomitant
Vertigo Other Serious 2/1/2009 Female 210 lb 3/25/2009 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 4/24/2009 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Other Serious 8/26/2003 37 Female 244 lb 5/14/2009 Other Health Professional United States
Primary
Concomitant
Skin Haemorrhage 1/19/2009 60 Female 165 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred 12/15/2008 61 Female 5/15/2009 United States
Primary
Concomitant
Radiation Skin Injury 5/12/2009 50 Female 229 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 5/28/2009 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/17/2009 64 Female 119 lb 6/3/2009 Physician Canada
Primary
Concomitant
Urticaria Other Serious 2/23/2009 41 Female 181 lb 6/4/2009 Other Health Professional United States
Primary
Concomitant
Metabolic Disorder Hospitalization 4/12/2009 75 Female 220 lb 6/4/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/26/2008 Female 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 3/15/2009 Female 300 lb 6/11/2009 United States
Primary
Concomitant
Anxiety 4/15/2009 Female 170 lb 6/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2008 Female 265 lb 6/12/2009 United States
Primary
Concomitant
Drug Ineffective Male 390 lb 6/12/2009
Primary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/15/2009 Physician United States
Primary
Concomitant
Pain Hospitalization 11/1/2007 60 Female 125 lb 6/15/2009 Pharmacist United States
Primary
Concomitant
Vertebral Injury Other Serious 1/1/2008 Female 202 lb 6/11/2009 Consumer United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 8/21/2009 Other Health Professional United States
Primary
Secondary
Blood Glucose Increased 6/1/2008 Male 210 lb 8/25/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Sudden Death Death 7/17/2009 76 Female 8/27/2009 United States
Primary
Secondary
Myocardial Infarction Death 7/17/2009 76 Female 8/31/2009 United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 201 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 9/4/2009 United States
Primary
Secondary
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 9/8/2009 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 9/1/2009 Female 9/22/2009 Physician United States
Primary
Secondary
Concomitant
Traumatic Brain Injury 8/5/2004 42 Female 198 lb 9/23/2009 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 73 Female 168 lb 10/1/2009 Consumer United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 9/24/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Sinus Rhythm Hospitalization 62 Female 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Vascular Rupture Other Serious 85 Female 10/12/2009
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 10/14/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2009 Female 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious Female 198 lb 12/31/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/19/2009 79 Female 163 lb 1/6/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death Male 130 lb 1/6/2010 Other Health Professional United States
Primary
Concomitant
Eructation 75 Male 1/4/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 2/1/2009 66 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Palpitations 3/23/2009 79 Female 12/15/2009 Physician United States
Primary
Concomitant
Alopecia 10/1/2009 45 Female 12/15/2009 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 12/18/2009 79 Female 163 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/1/2008 61 Female 1/5/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/14/2009 Female 1/19/2010 United States
Primary
Concomitant
Alopecia 5/1/2008 54 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 76 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 2/14/2010 Female 209 lb 2/23/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2010 76 Female 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 76 Female 3/2/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Sepsis Syndrome Other Serious 11/1/2008 Female 3/2/2010 Physician United States
Primary
Concomitant
Malaise Other Serious 2/19/2010 Female 3/1/2010 Physician United States
Primary
Concomitant
Neutropenia Other Serious Female 3/8/2010 Physician Canada
Primary
Concomitant
Skin Hypertrophy Other Serious 5/1/2009 44 Female 245 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Pancreatitis Acute Hospitalization 2/1/2006 Female 215 lb 3/17/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2009 59 Female 171 lb 3/18/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/29/2007 Male 184 lb 3/17/2010 Physician United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 3/22/2010 Consumer United States
Primary
Secondary
Renal Injury Hospitalization Female 3/22/2010 Physician United States
Primary
Concomitant
Sudden Death Death 7/17/2009 Female 201 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Sudden Death Death 7/17/2009 76 Female 201 lb 4/5/2010 Other Health Professional Germany
Primary
Secondary
Vomiting Hospitalization Male 209 lb 4/30/2010 Pharmacist United States
Primary
Concomitant
Lip Blister 67 Female 5/10/2010 Consumer United States
Primary
Concomitant
Carcinoid Tumour Of The Stomach Other Serious 4/1/2010 61 Female 5/10/2010 Consumer
Primary
Concomitant
Tumour Flare Other Serious 12/30/2008 80 Male 158 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 4/19/2008 79 Female 200 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 1/1/2009 66 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 60 Female 139 lb 5/17/2010 Consumer Brazil
Primary
Concomitant
Blindness Other Serious Female 5/17/2010 Consumer United States
Primary
Concomitant
Hepatic Steatosis 1/15/2010 62 Female 164 lb 5/17/2010 United States
Primary
Concomitant
Pruritus 3/1/2010 57 Female 180 lb 5/17/2010 Consumer United States
Primary
Concomitant
Small Intestinal Perforation Hospitalization 60 Female 285 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Heart Rate Decreased Male 5/18/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 75 Female 5/18/2010 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 115 lb 5/14/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 4/28/2010 69 Female 187 lb 5/20/2010 Other Health Professional United States
Primary
Concomitant
Hospitalisation Hospitalization 5/10/2010 66 Male 5/20/2010 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 1/1/2007 70 Female 5/21/2010 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/1/2009 48 Female 196 lb 5/26/2010 Consumer United States
Primary
Secondary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 53 Female 5/27/2010 Physician United States
Primary
Concomitant
Colon Cancer Hospitalization 8/1/2009 73 Female 168 lb 5/26/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 64 Female 6/17/2010 Physician Brazil
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 6/23/2010 Consumer United States
Primary
Secondary
Stomatitis Other Serious 7/1/2007 54 Male 215 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/22/2002 66 Female 190 lb 6/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 60 Female 234 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2005 43 Female 166 lb 6/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 65 Female 209 lb 7/7/2010 Physician United States
Primary
Concomitant
Tobacco User 4/7/2007 44 Female 267 lb 7/12/2010 Consumer United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Urticaria 1/1/2009 Female 225 lb 7/27/2010 Consumer United States
Primary
Concomitant
Impaired Gastric Emptying 1/1/2009 72 Female 135 lb 7/27/2010 Consumer United States
Primary
Concomitant
Diarrhoea 1/1/2008 65 Female 129 lb 7/27/2010 Consumer United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 7/28/2010 Consumer United States
Primary
Secondary
Myalgia 11/1/2008 61 Female 150 lb 7/31/2010 Consumer United States
Primary
Concomitant
Dry Eye 1/1/2008 64 Female 140 lb 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 64 Female 9/13/2010 Physician Brazil
Primary
Concomitant
Sepsis Neonatal Hospitalization 5/27/2009 6 lb 9/27/2010 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2010 61 Female 185 lb 9/15/2010 Consumer United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2010 61 Female 185 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
Retinal Vascular Disorder Other Serious 1/1/2009 69 Male 185 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Interacting
Nausea Other Serious 1/1/2010 Female 11/3/2010 Other Health Professional United States
Primary
Concomitant
Application Site Rash 7/1/2010 80 Female 156 lb 11/23/2010 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 69 Male 185 lb 12/8/2010 Physician Brazil
Primary
Concomitant
Injection Site Abscess Other Serious 9/7/2010 48 Male 284 lb 12/10/2010 Other Health Professional United States
Primary
Concomitant
Facial Pain Hospitalization 12/28/2000 45 Female 325 lb 2/14/2011 Lawyer United States
Primary
Concomitant
Thyroid Adenoma Hospitalization 9/2/2010 59 Male 400 lb 2/14/2011 Consumer United States
Primary
Concomitant
Back Pain Other Serious 9/22/2010 50 Female 3/21/2011 Physician Canada
Primary
Concomitant
Diarrhoea Hospitalization 1/2/2011 59 Female 3/18/2011 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 1/20/2011 86 Female 141 lb 5/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 1/1/2002 60 Female 170 lb 5/3/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2010 80 Female 5/4/2011 Consumer United States
Primary
Concomitant
Ankle Fracture Other Serious 3/1/2011 56 Female 270 lb 6/9/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 3/30/2011 Female 6/27/2011 Pharmacist United States
Primary
Concomitant
Pain Female 236 lb 7/19/2011 Consumer United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 12/31/2004 83 Female 209 lb 8/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Other Serious 1/1/2011 70 Female 8/24/2011 Brazil
Primary
Concomitant
Diarrhoea Hospitalization 5/9/2008 69 Female 9/2/2011 Lawyer United States
Primary
Concomitant

Drug Data