Metformin Hydrochloride combined with Ramipril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 6/8/2001 Male 1/3/2006 Australia
Primary
Concomitant
Urinary Retention Hospitalization 8/10/2000 Male 1/3/2006 France
Primary
Concomitant
Vertigo Hospitalization 11/16/2002 Male 1/4/2006 France
Primary
Concomitant
Cholelithiasis Hospitalization 11/14/2002 Male 1/4/2006 France
Primary
Concomitant
Tendon Disorder Hospitalization 6/18/2003 Male 1/4/2006 Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 72 Female 1/16/2006 Physician Denmark
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Lipase Increased Hospitalization 2/7/2006 63 Female 2/21/2006 Other Health Professional Italy
Primary
Concomitant
Cardiomyopathy Acute Hospitalization 2/7/2006 63 Female 3/3/2006 Other Health Professional Italy
Primary
Concomitant
Tachycardia Other Serious 2/12/2006 72 Female 161 lb 2/28/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Syncope Other Serious 65 Male 4/28/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/11/2006 57 Female 6/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 4/24/2006 70 Male 7/14/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Death 4/10/2004 64 Male 8/2/2006 Pharmacist
Primary
Concomitant
Lethargy Life Threatening 55 Male 8/23/2006 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 5/11/2006 57 Female 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Rash Other Serious 6/30/2006 66 Male 208 lb 6/30/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 3/17/2006 66 Female 9/1/2006 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 6/26/2006 71 Male 9/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Hospitalization 4/24/2006 70 Male 9/20/2006 United States
Primary
Secondary
Concomitant
Metabolic Acidosis Required Intervention 9/21/2006 71 Female 11/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 12/25/2005 Male 165 lb 11/27/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/25/2005 Male 165 lb 12/5/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 46 Male 4/3/2007 United Kingdom
Primary
Concomitant
Rales Other Serious 5/8/2007 75 Male 159 lb 6/4/2007 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 3/1/2007 78 Male 164 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening Female 7/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 60 Female 8/29/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/18/2007 60 Male 9/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 11/6/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Chest Pain Other Serious 7/1/2007 44 Male 182 lb 11/19/2007 Consumer United Kingdom
Primary
Concomitant
Mania Other Serious 1/1/2007 65 Male 11/19/2007 Physician Canada
Primary
Concomitant
Pancreatitis Acute Other Serious 10/19/2007 Male 11/16/2007 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 2/1/2007 46 Male 11/28/2007
Primary
Secondary
Hypertonia Hospitalization 8/10/2007 55 Male 220 lb 1/2/2008 Physician Switzerland
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 7/1/2007 61 Female 12/28/2007
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 87 Male 1/15/2008 Physician Germany
Primary
Concomitant
Gout Other Serious 8/28/2007 66 Male 4/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 75 Female 6/30/2008 Other Health Professional Sweden
Primary
Concomitant
Delusional Disorder, Unspecified Type Hospitalization 7/1/2008 Male 8/28/2008 Australia
Primary
Concomitant
Death Death 6/1/2008 64 Male 9/2/2008 Physician Norway
Primary
Concomitant
Hyperglycaemia Hospitalization 8/5/2008 73 Female 9/15/2008 Physician France
Primary
Concomitant
Vitamin B12 Decreased Other Serious 70 9/12/2008 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/18/2008 Physician Norway
Primary
Concomitant
Weight Decreased Hospitalization 12/25/2005 66 Male 9/19/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/25/2008 Physician Norway
Primary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/1/2007 Female 229 lb 10/14/2008 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 10/22/2008 Consumer Switzerland
Primary
Concomitant
Pallor Hospitalization Female 220 lb 10/24/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 5/11/2006 57 Female 10/22/2008 Denmark
Primary
Concomitant
Thrombosis Other Serious 2/13/2008 63 Male 214 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 9/1/2008 57 Male 214 lb 11/17/2008 Pharmacist Australia
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 12/3/2008 Physician Canada
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 12/4/2008 Physician Canada
Primary
Concomitant
Surgery Other Serious 11/13/2008 12/10/2008 Consumer Brazil
Primary
Concomitant
Malaise Hospitalization 1/1/2008 63 Male 12/16/2008 Physician Finland
Primary
Concomitant
Syncope Hospitalization 8/3/2008 60 Male 181 lb 1/5/2009 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 11/1/2008 1/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2008 72 Female 1/27/2009 Physician Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 1/1/2008 63 Male 2/11/2009 Physician Finland
Primary
Concomitant
Renal Failure Hospitalization 12/1/2008 65 Male 2/18/2009 Physician France
Primary
Concomitant
Surgery Other Serious 11/13/2008 2/19/2009 Consumer Brazil
Primary
Concomitant
Renal Failure Hospitalization 11/1/2008 65 Male 2/27/2009 Physician France
Primary
Concomitant
Death Hospitalization 3/9/2009 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Brain Stem Infarction Hospitalization 9/10/2006 46 Female 3/17/2009 Korea, Republic Of
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/9/2009 4/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/9/2009 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2008 71 5/7/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2008 67 Male 185 lb 6/2/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 55 Male 304 lb 6/2/2009 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 Male 194 lb 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Left Ventricular Failure Death 5/12/2009 69 Male 6/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 66 Male 6/16/2009 Physician Italy
Primary
Concomitant
Malaise Life Threatening 6/2/2008 83 Male 6/29/2009 Physician Australia
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2008 50 7/14/2009 Pharmacist Canada
Primary
Concomitant
Melaena Other Serious 11/5/2008 Male 7/23/2009 Other Health Professional
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/15/2008 Female 9/3/2009 Consumer Australia
Primary
Secondary
Concomitant
Completed Suicide Death 37 Female 9/8/2009 Physician United States
Primary
Secondary
Purpura Other Serious 7/7/2009 75 Male 9/9/2009 Other Health Professional
Primary
Secondary
Concomitant
Vasculitis Other Serious 7/7/2009 75 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 9/25/2009 United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Rash Generalised Other Serious 8/7/2006 Female 9/30/2009 United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 11/13/2008 64 Female 9/30/2009 United Kingdom
Primary
Concomitant
Skin Ulcer Life Threatening 72 Male 9/30/2009 United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 1/1/2009 Male 10/8/2009 Physician Canada
Primary
Concomitant
Bronchial Carcinoma Hospitalization 7/3/2009 70 Male 10/14/2009 Germany
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/15/2009 Physician United Kingdom
Primary
Concomitant
Foot Deformity Other Serious Female 190 lb 10/16/2009 Other Health Professional Canada
Primary
Concomitant
Medical Device Implantation Hospitalization 6/1/2009 61 Female 10/14/2009 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Asthma Other Serious 11/12/2009 Female 270 lb 12/1/2009 Physician United States
Primary
Concomitant
Hypomagnesaemia Other Serious 9/15/2009 61 Male 256 lb 12/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Life Threatening 12/24/2009 49 Male 191 lb 12/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/16/2009 Male 179 lb 1/13/2010 Physician Poland
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/8/2010 68 Male 267 lb 2/1/2010 Other Health Professional Canada
Primary
Concomitant
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 1/6/2010 60 Male 209 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/12/2009 82 Female 2/4/2010 Pharmacist Germany
Primary
Concomitant
Tremor Life Threatening 11/15/2008 76 Male 2/6/2010 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2009 Male 273 lb 2/22/2010 Physician United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 3/3/2010 Other Health Professional Norway
Primary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 3/3/2010 Other Health Professional Norway
Primary
Concomitant
Renal Failure Other Serious 12/18/2009 Male 207 lb 3/5/2010 Physician Germany
Primary
Concomitant
Thyroid Neoplasm Other Serious 10/5/2009 Male 227 lb 3/8/2010 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/1/2010 Male 260 lb 3/8/2010 Physician United Kingdom
Primary
Concomitant
Blood Glucose Abnormal Other Serious 2/1/2010 Male 3/9/2010 Consumer Germany
Primary
Concomitant
Urinary Retention Hospitalization 9/10/2009 Male 240 lb 3/10/2010 Physician United Kingdom
Primary
Concomitant
Arthritis Other Serious 2/11/2010 71 267 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 7/1/2008 Male 277 lb 3/10/2010 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 12/29/2009 66 Male 227 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 66 Male 3/11/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2007 Male 150 lb 3/15/2010 Physician Canada
Primary
Concomitant
Wheezing Other Serious 11/12/2009 Female 270 lb 3/22/2010 United States
Primary
Concomitant
Dehydration Hospitalization 1/8/2010 68 Male 267 lb 3/24/2010 Other Health Professional Canada
Primary
Concomitant
Diarrhoea Other Serious 1/15/2009 66 Male 214 lb 3/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 2/1/2010 Male 3/25/2010 Physician Germany
Primary
Concomitant
Multi-organ Failure Hospitalization 1/8/2010 68 Male 267 lb 3/30/2010 Other Health Professional Canada
Primary
Concomitant
Medication Error Other Serious Male 4/19/2010 Consumer United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 1/8/2010 68 Male 267 lb 4/19/2010 Other Health Professional Canada
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/12/2009 69 Male 4/26/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/13/2009 69 Male 4/30/2010
Primary
Concomitant
Fall Other Serious 12/1/2008 75 Female 150 lb 5/11/2010 Consumer Brazil
Primary
Secondary
Concomitant
Chest Pain Other Serious 3/12/2009 69 Male 5/12/2009 United States
Primary
Concomitant
Therapeutic Response Decreased Life Threatening 5/26/2008 66 Male 5/10/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 63 Male 5/13/2010 Other Health Professional France
Primary
Concomitant
Interacting
Cholelithiasis 12/4/2009 60 Male 222 lb 5/17/2010 Physician Germany
Primary
Secondary
Concomitant
Sinus Arrhythmia Hospitalization 3/24/2010 87 Male 5/17/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/12/2010 65 Male 243 lb 5/17/2010 Physician United Kingdom
Primary
Concomitant
Pruritus 3/1/2010 57 Female 180 lb 5/17/2010 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious 2/1/2010 59 Male 5/18/2010 Physician Germany
Primary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2009 65 Male 170 lb 5/18/2010 Canada
Primary
Concomitant
Loss Of Consciousness Other Serious 2/12/2010 60 Male 190 lb 5/19/2010 Other Health Professional Australia
Primary
Concomitant
Abdominal Pain Hospitalization 5/6/2010 52 Male 230 lb 5/20/2010 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 64 Male 194 lb 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 4/12/2010 54 Female 184 lb 5/21/2010 Other Health Professional Canada
Primary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 5/27/2010 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Other Serious 3/30/2010 60 Male 5/27/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 74 Male 5/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Interacting
Staphylococcal Infection Hospitalization 4/17/2010 77 Female 5/27/2010 Other Health Professional France
Primary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 5/19/2010 70 Female 163 lb 5/27/2010 Physician Canada
Primary
Secondary
Concomitant

Drug Data