Metformin Hydrochloride combined with Pravastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Monoparesis Hospitalization 3/11/2006 73 Male 142 lb 10/6/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 73 Female 7/6/2007 United Kingdom
Primary
Concomitant
Presyncope Other Serious 6/5/2007 Male 170 lb 7/23/2007 Physician France
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 6/17/2007 79 Male 8/28/2007 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 56 Female 4/3/2008 Physician France
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Other Serious 1/1/2007 48 Male 4/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Retinal Vein Occlusion Disability 3/21/2008 Male 185 lb 5/27/2008 Consumer Netherlands
Primary
Concomitant
Weight Increased Other Serious 3/1/2007 Female 143 lb 6/17/2008 Consumer Brazil
Primary
Concomitant
Retinal Vein Thrombosis Disability 3/21/2008 Male 185 lb 6/17/2008 Consumer Netherlands
Primary
Concomitant
Procedural Pain Hospitalization 5/29/2008 44 Female 8/22/2008 Mexico
Primary
Concomitant
Procedural Pain Hospitalization 5/29/2008 Female 152 lb 8/28/2008 Mexico
Primary
Concomitant
Weight Increased Hospitalization 54 Female 10/6/2008 Taiwan, Province Of China
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 9/12/2008 Female 105 lb 10/23/2008 Other Health Professional United States
Primary
Concomitant
Oesophagitis Other Serious 6/1/2008 78 Female 143 lb 10/30/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Male 348 lb 1/12/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2006 56 Male 4/6/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/21/2003 36 Female 188 lb 6/5/2009 United States
Primary
Concomitant
Pain Hospitalization 1/30/2006 50 Male 211 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Fatigue 2/19/2009 Male 280 lb 6/12/2009 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 3/3/2009 Male 264 lb 6/12/2009 United States
Primary
Concomitant
Vision Blurred Female 170 lb 6/12/2009 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 12/15/2007 Male 179 lb 6/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 203 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 8/31/2009 United Kingdom
Primary
Concomitant
Eye Haemorrhage Other Serious 73 Female 168 lb 10/1/2009 Consumer United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 10/14/2009 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/1/2007 65 Male 211 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 1/1/2009 Female 210 lb 11/25/2009 Consumer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 11/1/2009 Female 161 lb 12/3/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 1/1/2009 Female 210 lb 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2009 Female 196 lb 1/11/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Job Dissatisfaction 12/1/2007 57 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 2/10/2010 Male 141 lb 3/1/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 179 lb 3/22/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 1/14/2010 78 Male 3/25/2010 Physician Denmark
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious Male 4/5/2010 Physician United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/22/2010 47 Female 4/16/2010 France
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Somnolence Other Serious Male 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/1/2010 73 Male 180 lb 5/18/2010 Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/9/2010 70 Female 5/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Visual Impairment Other Serious Male 5/27/2010 Consumer United States
Primary
Concomitant
Interacting
Catheterisation Cardiac Abnormal Hospitalization 5/13/2010 59 Female 301 lb 5/27/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 7/27/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization Female 168 lb 9/10/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 68 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 2/5/2011 77 Female 227 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatic Enzymes Increased Other Serious 7/3/2010 57 Female 180 lb 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Convulsion Other Serious 8/28/2008 64 Male 3/29/2011 Consumer Denmark
Primary
Concomitant
Vomiting Life Threatening 1/11/2011 76 Male 4/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 7/3/2010 57 Female 180 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 5/23/2011 66 Male 216 lb 5/25/2011 Physician United States
Primary
Concomitant
Blood Triglycerides Increased Other Serious 7/3/2010 57 Female 180 lb 6/7/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 10/25/2010 72 Male 6/9/2011 Consumer France
Primary
Concomitant
Pituitary Cyst Life Threatening 6/21/2007 66 Female 106 lb 6/4/2011 Consumer United States
Primary
Concomitant
Apolipoprotein A-i Decreased Other Serious 56 Female 6/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bladder Cancer Hospitalization 7/12/2011 68 Female 7/28/2011 Other Health Professional Japan
Primary
Concomitant
Bacteriuria Hospitalization 1/1/2011 63 Female 8/31/2011 Other Health Professional France
Primary
Concomitant
Interacting
Hepatic Steatosis Hospitalization 63 Female 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Exertional Life Threatening 2/10/2011 67 Male 9/26/2011 Other Health Professional France
Primary
Secondary
Pulmonary Arterial Hypertension Life Threatening 2/10/2011 67 Male 227 lb 9/28/2011 Other Health Professional France
Primary
Secondary
Neuropathy Peripheral Hospitalization 6/11/2011 76 Male 178 lb 10/7/2011 Physician United States
Primary
Secondary
Concomitant
Blister 7/10/2001 59 Female 10/7/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Disability 6/9/2011 65 Female 200 lb 10/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 2/10/2011 67 Male 10/12/2011 Other Health Professional France
Primary
Secondary
Abnormal Behaviour Hospitalization Female 10/11/2011 Physician United States
Primary
Concomitant
Death Death 10/4/2011 78 Female 124 lb 10/17/2011 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 4/21/2011 65 Male 236 lb 10/17/2011 Physician United States
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 1/1/2010 64 Male 209 lb 1/4/2012 Pharmacist United States
Primary
Concomitant
Bile Duct Cancer Stage Iii Life Threatening 12/20/2011 69 Female 132 lb 3/8/2012 Physician France
Primary
Concomitant
Angioedema Other Serious 3/9/2012 Physician United States
Primary
Concomitant
Somnolence Other Serious 10/21/2010 58 Female 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/28/2012 78 Male 163 lb 6/18/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 3/18/2012 65 Male 6/27/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Dose Omission Hospitalization 8/15/2011 63 Male 172 lb 7/11/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2011 66 Female 200 lb 7/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fistula Other Serious 8/1/2011 72 Male 282 lb 7/13/2012 Physician Germany
Primary
Concomitant
Neoplasm Malignant Hospitalization 4/1/2010 63 Male 155 lb 7/13/2012 Consumer United States
Primary
Secondary
Concomitant
Microalbuminuria Hospitalization 8/13/2007 54 Male 209 lb 7/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Anaemia Hospitalization 5/7/2005 58 Male 174 lb 7/16/2012 Consumer United States
Primary
Secondary
Concomitant
Orthostatic Hypertension Death 8/13/2007 54 Male 209 lb 7/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 12/1/2011 60 Female 170 lb 7/16/2012 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 11/27/2011 62 Male 254 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Dizziness Death 8/13/2007 59 Male 209 lb 7/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Exposed Bone In Jaw Other Serious 1/1/2008 42 Female 7/17/2012 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/9/2011 66 Female 200 lb 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Irritation Other Serious 10/1/2009 70 Male 235 lb 7/5/2012 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia 62 Male 240 lb 7/18/2012 Physician United States
Primary
Concomitant
Asthenia Hospitalization 3/1/2012 86 Female 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Arthropathy Other Serious 1/1/2008 42 Female 7/19/2012 Lawyer United States
Primary
Concomitant
Headache 6/11/2012 79 Female 7/19/2012 Consumer United States
Primary
Concomitant
Atelectasis Other Serious 1/1/2008 42 Female 7/20/2012 Lawyer United States
Primary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 73 Male 7/23/2012 Physician Ireland
Primary
Secondary
Concomitant
Back Pain 7/14/2012 Male 7/23/2012 Consumer United States
Primary
Concomitant
Off Label Use 54 Female 154 lb 7/26/2012 United States
Primary
Concomitant
Nausea Hospitalization 40 Male 7/26/2012 Physician United States
Primary
Concomitant
Nausea Death 59 Male 7/13/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Infection Other Serious 5/7/2005 58 Male 174 lb 7/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 6/1/2012 55 Female 7/30/2012 Consumer United States
Primary
Concomitant
Immunosuppression Disability 6/9/2011 66 Female 200 lb 7/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Death 3/17/2010 67 Male 160 lb 7/30/2012 Physician United States
Primary
Concomitant
Fatigue Other Serious 11/14/2011 69 Male 7/24/2012 Physician Canada
Primary
Concomitant
Death Death 62 Male 7/31/2012 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 7/22/2012 65 Female 7/31/2012 Physician United States
Primary
Concomitant
Hypersensitivity Other Serious 3/21/2012 53 Male 285 lb 8/1/2012 Consumer United States
Primary
Concomitant
Asthenia Other Serious 5/11/2012 91 Female 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 4/12/2012 70 Male 246 lb 5/4/2012 Pharmacist United States
Primary
Concomitant
Eructation 6/1/2012 65 Female 8/2/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Neoplasm Other Serious 5/7/2005 58 Male 174 lb 8/3/2012 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Female 195 lb 8/3/2012 Consumer United States
Primary
Concomitant
Muscular Weakness 7/1/2011 53 Male 208 lb 8/3/2012 Consumer United States
Primary
Concomitant
Flushing Male 190 lb 8/3/2012 Consumer United States
Primary
Concomitant
Chest Pain 11/30/2011 49 Male 265 lb 8/3/2012 Consumer United States
Primary
Concomitant
Burning Sensation 150 lb 8/3/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 8/1/2011 61 Female 285 lb 8/3/2012 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 1/1/2008 42 Female 8/3/2012 Physician United States
Primary
Concomitant
Feeling Abnormal Female 184 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased 9/1/2011 45 Female 160 lb 8/3/2012 Consumer United States
Primary
Concomitant
Paraesthesia Male 250 lb 8/3/2012 Consumer United States
Primary
Concomitant
Skin Burning Sensation Female 8/3/2012 Consumer United States
Primary
Concomitant
Flushing Male 220 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Abnormal 1/1/2010 67 Male 200 lb 8/3/2012 Consumer United States
Primary
Concomitant
Feeling Hot 4/1/2012 57 Male 218 lb 8/3/2012 Consumer United States
Primary
Concomitant
Skin Burning Sensation 5/1/2012 48 Male 247 lb 8/3/2012 Consumer United States
Primary
Concomitant
Pruritus 3/26/2012 71 Female 196 lb 8/3/2012 Consumer United States
Primary
Concomitant
Pruritus 5/1/2012 48 Male 255 lb 8/3/2012 Consumer United States
Primary
Secondary
Concomitant
Flushing Male 250 lb 8/3/2012 Consumer United States
Primary
Concomitant
Tongue Disorder 1/1/2011 85 Female 7/31/2012 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/1/2008 42 Female 8/7/2012 Physician United States
Primary
Concomitant
Acute Respiratory Failure Other Serious 5/7/2005 58 Male 174 lb 8/8/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 42 Female 8/8/2012 Physician United States
Primary
Concomitant
Incorrect Route Of Drug Administration 8/6/2012 73 Female 8/9/2012 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/12/2009 48 Male 220 lb 8/9/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Test Abnormal Other Serious 1/1/2012 74 Male 236 lb 8/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Crying Hospitalization 5/22/2012 58 Male 210 lb 8/13/2012 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2008 42 Female 8/14/2012 Lawyer United States
Primary
Concomitant
Ankle Fracture Hospitalization 5/1/2012 54 Male 342 lb 8/14/2012 Other Health Professional United States
Primary
Concomitant
Infection Hospitalization 1/1/2009 67 Male 160 lb 8/17/2012 Consumer United States
Primary
Concomitant
Coronary Angioplasty Other Serious 11/19/2009 Male 8/17/2012 Consumer Germany
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/21/2012 40 Female 320 lb 8/7/2012 Consumer United States
Primary
Concomitant

Drug Data