Metformin Hydrochloride combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Psychotic Disorder Hospitalization 6/1/2005 59 Male 262 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 11/12/2005 64 Male 3/1/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 1/19/2006 59 Male 262 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 12/1/2004 70 Female 125 lb 12/21/2005 Consumer United States
Primary
Concomitant
Cough Other Serious 1/31/2006 74 Male 256 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Spinal Shock Hospitalization 2/2/2006 58 Female 3/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 9/13/2005 64 Male 209 lb 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 4/24/2006 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 3/1/2006 56 Male 196 lb 3/1/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Ear Pain Hospitalization 12/1/2005 59 Female 238 lb 5/31/2006 Physician Australia
Primary
Secondary
Concomitant
Drug Therapy Changed 3/2/2006 Male 131 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Swelling 4/24/2006 Male 418 lb 6/30/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 5/15/2006 38 Male 234 lb 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/5/2006 70 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 5/12/2006 75 Male 170 lb 5/12/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2005 78 Male 202 lb 7/21/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/10/2005 45 Female 1/27/2006 United States
Primary
Concomitant
Ear Pain Hospitalization 12/1/2005 59 Female 238 lb 8/11/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatic Function Abnormal 6/29/2006 67 Male 9/8/2006 Japan
Primary
Secondary
Concomitant
Iiird Nerve Paresis Disability 11/19/2006 63 Female 157 lb 2/6/2007 Consumer United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 83 Male 178 lb 12/13/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 51 Female 5/30/2007 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/1/2007 78 Male 164 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 6/4/2007 61 Female 190 lb 7/3/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 73 Female 7/6/2007 United Kingdom
Primary
Concomitant
Hypotension Hospitalization 4/30/2007 75 Male 7/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Thrombosis Other Serious 3/1/2007 Female 239 lb 10/26/2007 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/13/2006 Female 11/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 11/13/2007 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 3/1/2007 Female 239 lb 11/26/2007 United States
Primary
Concomitant
Renal Failure Other Serious 1/24/2006 68 Male 227 lb 1/7/2008 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/16/2007 75 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Epistaxis Other Serious 2/13/2008 74 Male 3/18/2008 United Kingdom
Primary
Concomitant
Fatigue Other Serious 50 Female 268 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 9/1/2006 60 Female 242 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Glossodynia 9/15/2007 Female 182 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected Female 175 lb 8/27/2008 United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 7/16/2008 85 Female 9/12/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 9/5/2008 59 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/1/2003 56 Male 10/20/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 46 Female 390 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Underdose Hospitalization 10/13/2008 81 Male 10/17/2008 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Myoclonus Hospitalization 46 Female 390 lb 10/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 10/22/2008 Consumer Switzerland
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 1/1/2007 Male 10/24/2008 Physician United States
Primary
Concomitant
Flushing 1/1/2008 77 Male 10/27/2008 Consumer Germany
Primary
Concomitant
Product Quality Issue 3/18/2008 66 Male 10/30/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/7/2008 66 Male 168 lb 11/11/2008 Physician France
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/9/2009 Consumer Brazil
Primary
Concomitant
Perivascular Dermatitis Hospitalization 5/24/2006 1/12/2009 Other Health Professional Australia
Primary
Secondary
Vision Blurred Other Serious 7/29/2008 1/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 1/22/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/28/2009 Consumer Brazil
Primary
Concomitant
Completed Suicide Death 37 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Blood Pressure Increased 11/15/2008 62 Female 291 lb 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 77 Male 4/16/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 5/1/2009 Physician Japan
Primary
Concomitant
Product Substitution Issue Other Serious 1/1/2009 61 Female 3/25/2009 Pharmacist United States
Primary
Concomitant
Priapism Hospitalization 5/1/2009 65 Male 156 lb 5/15/2009 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus 12/30/2004 31 Male 160 lb 5/21/2009 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 5/10/2009 67 Male 210 lb 5/24/2009 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/1/2008 64 Male 4/24/2009 United States
Primary
Secondary
Concomitant
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Thrombocytopenia Other Serious 49 Female 6/2/2009 Spain
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious Male 216 lb 6/3/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 4/1/2001 45 Female 232 lb 6/5/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 Male 194 lb 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 4/23/2009 Male 550 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 11/12/2008 Female 192 lb 6/11/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/9/2008 Male 6/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 4/15/2009 74 Female 172 lb 6/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations Other Serious 5/12/2009 73 Female 6/12/2009 Physician United Kingdom
Primary
Concomitant
Nausea Disability 4/30/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Vertebral Injury Other Serious 1/1/2008 Female 202 lb 6/11/2009 Consumer United States
Primary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 66 Male 6/16/2009 Physician Italy
Primary
Concomitant
Rash Pruritic Hospitalization 6/20/2009 77 Female 7/1/2009 Consumer United States
Primary
Concomitant
Volvulus Hospitalization 1/1/2008 Female 270 lb 7/14/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/13/2009 Male 275 lb 8/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Purpura Other Serious 7/7/2009 75 Male 9/9/2009 Other Health Professional
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 6/25/2009 76 Male 187 lb 9/25/2009 Germany
Primary
Concomitant
Interacting
Weight Increased Other Serious 6/1/2008 Female 207 lb 9/29/2009 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Life Threatening 6/25/2009 76 Male 187 lb 9/30/2009 Germany
Primary
Concomitant
Interacting
Vasculitis Other Serious 7/7/2009 75 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/30/2009 41 Female 198 lb 10/13/2009 Other Health Professional Singapore
Primary
Concomitant
Irritable Bowel Syndrome 3/1/2009 Female 10/16/2009 Consumer
Primary
Concomitant
Foot Deformity Other Serious Female 190 lb 10/16/2009 Other Health Professional Canada
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 76 Female 10/19/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 6/14/2007 Male 188 lb 10/19/2009 Physician New Zealand
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/20/2009 83 Male 10/22/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/13/2009 Male 275 lb 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/20/2009 83 Male 10/27/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 10/28/2009 Pharmacist United Kingdom
Primary
Secondary
Dehydration Hospitalization 8/10/2009 Male 275 lb 11/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 11/6/2009 Pharmacist United Kingdom
Primary
Secondary
Multiple Myeloma Other Serious 1/1/2007 57 Male 12/14/2009 Consumer France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 39 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 1/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 70 Female 12/23/2009 Physician Israel
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 11/16/2009 Female 1/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 8/4/2009 50 Female 12/30/2009 United Kingdom
Primary
Concomitant
Vomiting 10/25/2009 72 Female 1/4/2010 Consumer United States
Primary
Concomitant
Gastrointestinal Carcinoma Death 10/1/2009 65 Female 198 lb 1/11/2010 Physician Netherlands
Primary
Concomitant
Urticaria 43 Male 270 lb 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/16/2009 Male 179 lb 1/13/2010 Physician Poland
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/16/2009 Male 179 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 12/30/2009 1/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/8/2010 68 Male 267 lb 2/1/2010 Other Health Professional Canada
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 3/26/2009 86 Female 110 lb 2/18/2010 Consumer Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2010 61 Male 2/12/2010 Other Health Professional Czech Republic
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 211 lb 2/25/2010 Consumer United States
Primary
Concomitant
Walking Disability Other Serious 8/1/2009 Female 2/25/2010 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 12/27/2009 61 Male 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Other Serious 10/14/2009 Male 3/2/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 68 Female 146 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 12/30/2009 3/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 66 Female 151 lb 3/5/2010 Consumer United States
Primary
Concomitant
Cholecystitis Acute Hospitalization 11/16/2009 Female 130 lb 3/5/2010 Physician India
Primary
Concomitant
Death Death 1/26/2010 81 Male 185 lb 3/5/2010 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/1/2010 Male 260 lb 3/8/2010 Physician United Kingdom
Primary
Concomitant

Drug Data