Metformin Hydrochloride combined with Norvasc

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Death 1/1/2004 77 Male 192 lb 2/7/2006 Physician Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2002 79 Female 201 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2006 63 Male 207 lb 4/26/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/1/2003 52 Male 199 lb 4/24/2006 Physician United States
Primary
Concomitant
Hypotension 3/8/2006 66 Male 6/28/2006 United States
Primary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Physician Canada
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Cholelithiasis Hospitalization 7/3/2006 48 Female 274 lb 8/22/2006 Consumer United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization 1/1/2006 67 Male 132 lb 9/14/2006 Physician Canada
Primary
Concomitant
Cholelithiasis Hospitalization 7/3/2006 48 Female 274 lb 11/3/2006 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 12/21/2006 Physician Canada
Primary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Bradycardia Hospitalization 12/21/2006 70 Male 2/5/2007 Japan
Primary
Concomitant
Atrioventricular Block Second Degree Life Threatening 12/21/2006 72 Male 3/1/2007 Japan
Primary
Concomitant
Atrioventricular Block Second Degree Life Threatening 12/21/2006 72 Male 3/9/2007 Japan
Primary
Concomitant
Skin Disorder Other Serious 5/10/2007 61 Male 6/19/2007 Physician Japan
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Male 216 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Eczema 5/12/2007 61 Male 172 lb 7/5/2007 Physician Japan
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 9/30/2006 80 Male 150 lb 8/9/2007 Physician Japan
Primary
Concomitant
Lip Exfoliation 4/15/2007 Female 10/2/2007 Pharmacist United States
Primary
Concomitant
Hyperuricaemia Hospitalization 5/10/2007 63 Male 192 lb 12/3/2007 Japan
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 5/10/2007 63 Male 192 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Renal Failure Disability 1/23/2008 61 Male 2/21/2008 Consumer Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/1/2008 Female 128 lb 6/2/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/1/2008 Female 128 lb 6/9/2008 Physician Japan
Primary
Concomitant
Pain Hospitalization 10/5/2008 73 Female 146 lb 10/8/2008 Pharmacist United States
Primary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/25/2002 54 Male 226 lb 10/20/2008 Lawyer United States
Primary
Concomitant
Gastrointestinal Ulcer Other Serious 1/1/2008 81 Female 130 lb 10/20/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 10/22/2008 Consumer Switzerland
Primary
Concomitant
Tooth Extraction Other Serious 10/25/2004 Male 212 lb 12/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 10/11/2004 Male 212 lb 2/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 3/8/2008 Male 165 lb 3/6/2009 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/23/2009 88 Female 3/31/2009 Other Health Professional Norway
Primary
Concomitant
Nightmare 9/23/2008 58 Male 248 lb 4/14/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2004 Male 212 lb 5/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia 2/25/2009 57 Female 225 lb 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paralysis Hospitalization 1/1/2002 42 Male 150 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization 5/26/2009 Male 6/5/2009 Canada
Primary
Concomitant
Vomiting Hospitalization 5/21/2009 Female 136 lb 6/15/2009 Physician United States
Primary
Concomitant
Shock Hospitalization 11/1/2006 58 Female 6/15/2009 Other Health Professional United States
Primary
Concomitant
Malaise Life Threatening 6/21/2009 83 Male 139 lb 7/20/2009 Other Health Professional Japan
Primary
Concomitant
Synovitis Other Serious 2/29/2000 37 Female 212 lb 7/28/2009 United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 8/21/2009 Other Health Professional United States
Primary
Secondary
Pancreatitis Other Serious 2/20/2009 Male 291 lb 8/23/2009 Consumer Australia
Primary
Concomitant
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Sudden Death Death 7/17/2009 76 Female 8/27/2009 United States
Primary
Secondary
Myocardial Infarction Death 7/17/2009 76 Female 8/31/2009 United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 201 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 9/4/2009 United States
Primary
Secondary
Pancreatitis Other Serious 2/20/2009 Male 291 lb 9/7/2009 Physician Australia
Primary
Concomitant
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 9/8/2009 Other Health Professional United States
Primary
Secondary
Stent Placement Hospitalization 8/12/2009 67 Male 265 lb 9/30/2009 Consumer United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Syncope Hospitalization 56 Female 260 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/1/2009 Female 10/12/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2009 Female 146 lb 10/13/2009 Consumer United States
Primary
Concomitant
Diarrhoea 9/1/2009 Female 10/16/2009 Physician United States
Primary
Concomitant
Medical Device Implantation Hospitalization 6/1/2009 61 Female 10/14/2009 Consumer Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 10/1/2001 52 Male 198 lb 10/22/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
Microalbuminuria Other Serious 12/1/2009 Male 1/6/2010 Physician Canada
Primary
Concomitant
Product Quality Issue 5/16/2009 60 Male 1/4/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 9/21/2006 52 Female 139 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemic Seizure Other Serious 10/2/2008 59 Male 1/12/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 212 lb 1/14/2010 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 11/1/2009 Female 1/14/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/22/2009 65 Female 1/15/2010 Consumer Turkey
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 212 lb 2/10/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 212 lb 2/15/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 212 lb 2/18/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 2/5/2010 United States
Primary
Concomitant
Wheezing Hospitalization 79 Male 2/5/2010 United States
Primary
Concomitant
Partial Seizures Hospitalization 2/10/2010 53 Male 253 lb 3/1/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 212 lb 3/12/2010 United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Wegener's Granulomatosis Hospitalization 6/23/2008 Female 154 lb 3/18/2010 Other Health Professional Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 3/18/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 10/1/2006 59 Male 297 lb 3/17/2010 Physician United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 3/22/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 10/1/2007 68 Male 159 lb 3/22/2010 Lawyer United States
Primary
Concomitant
Sudden Death Death 7/17/2009 Female 201 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 214 lb 3/30/2010 United States
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 4/5/2010 Other Health Professional Germany
Primary
Secondary
Urine Albumin/creatinine Ratio Increased Other Serious 2/24/2010 79 Male 5/10/2010 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 5/12/2010 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 4/20/2010 68 Male 240 lb 5/13/2010 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 58 Female 5/13/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 5/14/2010 United States
Primary
Concomitant
Motor Dysfunction Hospitalization 12/30/2009 66 Male 190 lb 5/17/2010 Physician Switzerland
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 66 Male 226 lb 5/18/2010 Pharmacist United States
Primary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2009 65 Male 170 lb 5/18/2010 Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 5/19/2010 United States
Primary
Concomitant
Abdominal Pain Hospitalization 5/6/2010 52 Male 230 lb 5/20/2010 Physician Canada
Primary
Concomitant
Bronchitis Life Threatening Male 230 lb 5/28/2010 Physician Canada
Primary
Concomitant
Abdominal Pain Hospitalization 5/6/2010 52 Male 230 lb 5/28/2010 Physician Canada
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 6/23/2010 Consumer United States
Primary
Secondary
Drug Ineffective 4/18/2007 88 Female 99 lb 6/30/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Nausea 9/16/2008 72 Female 150 lb 7/23/2010 Consumer United States
Primary
Concomitant
Urticaria 1/1/2009 Female 225 lb 7/27/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 7/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 7/17/2009 76 Female 7/28/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2009 86 Female 117 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Anaemia Hospitalization 10/4/2010 78 Female 157 lb 10/26/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
Nephrogenic Anaemia Hospitalization 10/4/2010 78 Female 139 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 11/2/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 11/9/2010 Pharmacist United States
Primary
Secondary
Concomitant
Nephrogenic Anaemia Hospitalization 10/4/2010 79 Female 139 lb 11/10/2010 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/29/2000 37 Female 214 lb 12/17/2010 United States
Primary
Concomitant
Hypoaesthesia Oral 102 Male 11/23/2010 Consumer United States
Primary
Concomitant
Joint Sprain Hospitalization 10/25/2004 70 Male 212 lb 2/11/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 61 Male 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 8/9/2010 68 Male 3/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Anaemia Other Serious 11/1/2009 87 Female 117 lb 4/7/2011 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/26/2011 55 Female 131 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious Male 4/13/2011 Physician United States
Primary
Concomitant
Fear Other Serious 3/10/2006 58 Male 301 lb 5/25/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 1/21/2009 27 Female 295 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious Female 6/7/2011 Consumer United States
Primary
Concomitant
Urine Cytology Abnormal Hospitalization 6/9/2006 62 Female 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 7/26/2011 Japan
Primary
Concomitant
Facial Bones Fracture Other Serious 1/1/2005 63 Male 216 lb 8/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyuria Life Threatening 4/19/2011 78 Female 8/16/2011 Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 12/1/2010 74 Female 170 lb 8/22/2011 Physician United States
Primary
Concomitant
Oedema Peripheral 6/29/2011 Male 8/29/2011 Pharmacist United States
Primary
Concomitant
Generalised Oedema Hospitalization 5/1/2011 51 Male 177 lb 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/9/2006 62 Female 8/31/2011 Other Health Professional Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2011 63 Female 233 lb 8/25/2011 Pharmacist United States
Primary
Concomitant
Gallbladder Non-functioning Other Serious 1/1/2009 59 Male 280 lb 9/15/2011 United States
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 5/1/2011 51 Male 177 lb 9/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bladder Cancer Life Threatening 4/19/2011 78 Female 9/28/2011 Japan
Primary
Secondary
Concomitant
Lipogranuloma Hospitalization 7/7/2011 87 Female 10/3/2011 Other Health Professional Germany
Primary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 10/4/2011 Japan
Primary
Concomitant
Nausea Other Serious 9/30/2011 50 Female 10/9/2011 Consumer Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/7/2011 64 Male 195 lb 10/10/2011 Physician United States
Primary
Concomitant
Interacting
Nausea Other Serious 9/30/2011 50 Female 10/11/2011 Consumer Canada
Primary
Concomitant
Urosepsis Life Threatening 6/20/2011 43 Female 168 lb 10/11/2011 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/1/2011 71 Male 10/14/2011 Pharmacist Canada
Primary
Concomitant
Diarrhoea 9/1/2011 Male 10/14/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data