Metformin Hydrochloride combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Death 1/1/2004 77 Male 192 lb 2/7/2006 Physician Canada
Primary
Concomitant
Left Ventricular End-diastolic Pressure Increased Hospitalization 3/9/2004 65 Male 271 lb 2/16/2006 Physician United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/6/2005 59 Female 3/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/6/2005 59 Female 3/13/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Cough Other Serious 1/31/2006 74 Male 256 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 69 Female 4/26/2006 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/6/2005 59 Female 4/27/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 8/25/2006 73 Male 178 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/7/2006 77 Male 236 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/18/2007 60 Male 9/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vasculitic Rash Other Serious 8/31/2007 73 Male 10/12/2007 United States
Primary
Concomitant
Arteriospasm Coronary Life Threatening 3/22/2007 77 Female 206 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 11/13/2007 Consumer United States
Primary
Concomitant
Skin Laceration Other Serious 8/1/2007 60 Male 5/12/2008 United States
Primary
Concomitant
Delusional Disorder, Unspecified Type Hospitalization 7/1/2008 Male 8/28/2008 Australia
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 217 lb 10/18/2008 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 217 lb 10/20/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 9/1/2008 Female 214 lb 10/21/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 217 lb 10/24/2008 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 10/29/2008 56 Male 220 lb 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 9/1/2008 72 Female 5/15/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 4/23/2009 Male 550 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2005 50 Male 260 lb 7/22/2009 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/29/2008 73 Male 220 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Graft Occlusion Other Serious 3/13/2008 63 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/29/2008 73 Male 220 lb 9/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 8/3/2003 44 Female 273 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 9/24/2009 United States
Primary
Concomitant
Syncope Hospitalization 56 Female 260 lb 9/25/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 56 Male 9/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
Cardiogenic Shock Life Threatening 9/18/2009 52 Male 152 lb 10/12/2009 Physician Canada
Primary
Concomitant
Temperature Intolerance Other Serious 8/6/2009 Female 220 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/25/2009 Male 309 lb 10/16/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1990 Female 220 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiogenic Shock Life Threatening 9/18/2009 52 Male 152 lb 10/19/2009 Physician Canada
Primary
Concomitant
Muscle Rupture Hospitalization Male 10/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Hyperhidrosis 5/1/2008 75 Female 113 lb 11/11/2009 Consumer United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 11/16/2009 74 Female 163 lb 12/30/2009 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/21/2006 Female 148 lb 1/12/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 41 Male 256 lb 1/15/2010 United States
Primary
Concomitant
Gastrointestinal Angiodysplasia Hospitalization 11/2/2009 76 Male 180 lb 1/15/2010 Physician Australia
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 2/18/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 2/5/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 71 Female 2/5/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 71 Female 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Nausea Hospitalization 76 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2010 76 Female 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 76 Female 3/2/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2010 Male 235 lb 3/3/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Therapeutic Response Unexpected 66 Female 151 lb 3/5/2010 Consumer United States
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization Male 280 lb 3/15/2010 Physician Spain
Primary
Concomitant
Low Density Lipoprotein Increased 1/11/2010 Male 260 lb 3/16/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 12/1/2008 Female 235 lb 3/17/2010 Physician United States
Primary
Concomitant
Renal Injury Hospitalization Female 3/22/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1990 57 Female 220 lb 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Steatosis 1/15/2010 62 Female 164 lb 5/17/2010 United States
Primary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 -1 Male 154 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 7/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 2/10/2010 76 Female 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased 1/1/2009 70 Male 202 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Increased 10/1/2008 86 Male 141 lb 9/14/2010 Consumer United States
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/3/2008 62 Male 1/12/2011 Consumer Japan
Primary
Concomitant
Renal Function Test Abnormal Other Serious 12/3/2008 62 Male 1/31/2011 Consumer Japan
Primary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 11/27/2010 77 Female 2/14/2011 Other Health Professional France
Primary
Concomitant
Asthenia Hospitalization 1/1/2008 52 Male 256 lb 3/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Blindness Other Serious 1/1/2008 52 Male 256 lb 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 9/4/2004 57 Female 230 lb 5/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Fear Other Serious 3/10/2006 58 Male 301 lb 5/25/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 5/26/2010 70 Male 154 lb 6/28/2011 Other Health Professional United States
Primary
Concomitant
Blindness Hospitalization 1/1/2008 52 Male 256 lb 7/25/2011 Lawyer United States
Primary
Secondary
Concomitant
Depression Other Serious 10/1/2001 58 Male 205 lb 8/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Facial Bones Fracture Other Serious 1/1/2005 63 Male 216 lb 8/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Other Serious 4/3/2008 83 Male 180 lb 8/22/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 10/1/2001 59 Male 205 lb 8/24/2011 Physician United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 5/8/2011 83 Female 152 lb 9/12/2011 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/7/2011 64 Male 195 lb 10/10/2011 Physician United States
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Other Serious 8/1/2010 85 Female 165 lb 9/28/2011 Physician United States
Primary
Concomitant
Interacting
Aortic Aneurysm Other Serious 9/15/2011 69 Male 169 lb 10/17/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/4/2011 69 Male 10/18/2011 Physician United States
Primary
Concomitant
Lactic Acidosis Life Threatening 12/14/2011 54 Male 1/11/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/9/2011 54 Male 1/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypothermia Life Threatening 12/14/2011 54 Male 1/23/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Cervical Cord Compression Hospitalization 10/6/2011 72 Male 1/23/2012 Hong Kong
Primary
Secondary
Iron Deficiency Anaemia Other Serious Male 221 lb 3/16/2012 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/21/2012 45 Male 227 lb 3/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Oedema Hospitalization 5/1/2012 72 Female 7/10/2012 Physician Italy
Primary
Concomitant
Pneumonia Aspiration Other Serious 6/7/2012 72 Male 7/13/2012 Consumer Canada
Primary
Concomitant
Tongue Oedema Hospitalization 5/1/2012 72 Female 7/13/2012 Physician Italy
Primary
Concomitant
Pneumonia Hospitalization 11/29/2011 86 Female 177 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/29/2011 86 Female 177 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 8/1/2011 66 Male 197 lb 7/16/2012 Other Health Professional Australia
Primary
Concomitant
Sepsis Hospitalization 10/2/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/6/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Intervertebral Discitis Hospitalization 12/28/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 5/1/2012 72 Female 7/16/2012 Physician Italy
Primary
Concomitant
Back Pain Hospitalization 9/21/2011 61 Male 229 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 6/7/2012 72 Male 7/17/2012 Physician Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/1/2011 71 Male 220 lb 7/18/2012 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 4/1/2010 7/18/2012 Physician United States
Primary
Secondary
Concomitant
Arteriosclerosis Coronary Artery Other Serious Female 7/20/2012 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/18/2012 66 Female 7/9/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 3/1/2008 79 Male 7/23/2012 Physician Argentina
Primary
Secondary
Concomitant
Injury Other Serious Male 7/9/2012 Lawyer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 7/1/2012 77 Male 204 lb 7/25/2012 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus 1/1/2003 54 Female 200 lb 7/27/2012 United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 3/30/2012 88 Female 7/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Formication 7/19/2011 64 Female 245 lb 8/1/2012 Other Health Professional United States
Primary
Concomitant
Vertigo Hospitalization 5/10/2012 91 Female 7/12/2012 Physician Italy
Primary
Concomitant
Impaired Work Ability 52 Female 8/1/2012 United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/13/2012 87 Male 179 lb 3/15/2012 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization Female 8/3/2012 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/7/2011 48 Male 256 lb 8/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Male 210 lb 8/3/2012 Consumer United States
Primary
Concomitant
Fall Other Serious 6/26/2012 86 Female 220 lb 8/9/2012 Other Health Professional Canada
Primary
Concomitant
Colon Cancer Other Serious 10/2/2011 8/9/2012 Physician Singapore
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/14/2012 60 Male 357 lb 8/13/2012 Physician United Kingdom
Primary
Concomitant
Catheterisation Cardiac Hospitalization 2/1/2007 47 Female 282 lb 8/17/2012 Physician United States
Primary
Concomitant
Wound Hospitalization 12/28/2011 61 Male 229 lb 6/29/2012 Physician Us
Primary
Secondary
Concomitant
Back Pain Hospitalization 9/21/2011 61 Male 229 lb 6/29/2012 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/2/2011 72 Male 262 lb 11/6/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Malaise Other Serious 58 Male 4/15/2013 Other Health Professional Us
Primary
Secondary
Concomitant

Drug Data