Metformin Hydrochloride combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 11/1/2005 49 Male 1/31/2006 Physician Germany
Primary
Concomitant
Stomatitis Hospitalization 10/19/2005 71 Female 2/9/2006 Physician Switzerland
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/26/2006 85 Male 198 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control 56 Female 259 lb 12/14/2006 United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 4/25/2007 Sweden
Primary
Concomitant
Drug Ineffective Hospitalization 3/4/2006 56 Female 120 lb 12/13/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/4/2004 58 Female 8/7/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/4/2004 58 Female 8/31/2007 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/16/2005 Female 172 lb 9/7/2007 Physician Turkey
Primary
Concomitant
Nail Disorder Female 195 lb 9/12/2007 United States
Primary
Concomitant
Rash Other Serious 10/14/2007 68 Female 11/27/2007 Sweden
Primary
Concomitant
Pharyngolaryngeal Pain 1/26/2008 Female 201 lb 3/15/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 7/21/2008 United States
Primary
Concomitant
Thrombosis Hospitalization 12/30/2008 2/13/2009 Other Health Professional Netherlands
Primary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Secondary
Concomitant
Peripheral Ischaemia 9/1/2008 78 Male 171 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Sudden Death Other Serious Male 6/1/2009 Other Health Professional New Zealand
Primary
Secondary
Myocardial Infarction Hospitalization 4/1/2004 42 Female 211 lb 6/4/2009 Consumer United States
Primary
Concomitant
Death Death 5/27/2009 Male 240 lb 6/3/2009 Physician United States
Primary
Concomitant
Transfusion Hospitalization 5/6/2009 Male 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 4/23/2009 Male 6/1/2009 Physician Germany
Primary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Drug Ineffective 6/1/2008 Female 6/11/2009 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/4/2009 74 Male 170 lb 6/12/2009 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Death 12/1/2008 82 Female 6/12/2009 United States
Primary
Concomitant
Coronary Artery Disease Death 5/27/2009 Male 240 lb 6/10/2009 Physician United States
Primary
Concomitant
Shock Hospitalization 11/1/2006 58 Female 6/15/2009 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 6/15/2009 Consumer United States
Primary
Concomitant
Renal Injury Hospitalization 1/1/1999 48 Female 250 lb 6/15/2009 Pharmacist United States
Primary
Concomitant
Angina Unstable Hospitalization 1/13/2009 Male 292 lb 6/12/2009 Consumer United States
Primary
Concomitant
Skin Laceration 4/2/2009 Female 202 lb 6/15/2009 Consumer United States
Primary
Concomitant
Headache 4/26/2009 Female 139 lb 6/15/2009 Consumer United States
Primary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/1/2008 77 Female 6/18/2009 Germany
Primary
Concomitant
Dizziness Male 8/21/2009 United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2008 Female 207 lb 9/29/2009 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 183 lb 9/21/2009 United States
Primary
Concomitant
Respiratory Disorder Death 68 Male 9/18/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 8/24/2009 41 Female 9/30/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Penile Oedema Other Serious 6/1/2009 56 Male 10/16/2009 Pharmacist Germany
Primary
Concomitant
Pyrexia Hospitalization 5/15/2009 Female 197 lb 10/28/2009 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/8/2010 78 Female 142 lb 5/14/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Life Threatening 3/10/2010 43 Female 5/19/2010 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 5/17/2010 81 Female 148 lb 9/28/2010 Consumer Brazil
Primary
Concomitant
Swelling Face Other Serious 8/29/2010 84 Male 150 lb 10/8/2010 Consumer Brazil
Primary
Concomitant
Vasculitis Other Serious 10/29/2007 63 Male 262 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 67 Female 12/2/2010 Physician United States
Primary
Concomitant
Lactic Acidosis Hospitalization 67 Female 12/2/2010 Physician United States
Primary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Neutropenic Colitis Hospitalization 3/4/2010 69 Male 211 lb 2/25/2011 Physician United States
Primary
Concomitant
Panic Reaction Other Serious 1/1/2010 49 Male 300 lb 4/7/2011 United States
Primary
Secondary
Concomitant
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 1/15/2007 59 Male 6/9/2011 Pharmacist United States
Primary
Concomitant
Atrial Thrombosis Other Serious 57 6/9/2011 Other Health Professional Brazil
Primary
Concomitant
Pain In Extremity 5/19/2011 73 Male 6/9/2011 Consumer United States
Primary
Concomitant
Facial Paresis Hospitalization 7/14/2010 62 Male 6/9/2011 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious Female 6/7/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 4/1/2011 70 Male 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Inflammation Other Serious 6/1/2010 54 Male 6/24/2011 Brazil
Primary
Concomitant
Diverticulitis Other Serious 1/1/2010 77 Male 7/18/2011 Consumer Brazil
Primary
Secondary
Concomitant
Confusional State Hospitalization 1/1/2009 80 Female 157 lb 7/21/2011 Consumer Brazil
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious 4/29/2011 57 Male 253 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 8/19/2011 Physician United States
Primary
Concomitant
Choking Sensation 1/1/2010 80 Male 8/20/2011 Consumer United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 72 Female 8/22/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Erythema Other Serious 5/4/2011 62 Female 190 lb 8/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 3/10/2011 82 Male 172 lb 8/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Faecal Incontinence Hospitalization 82 Female 8/30/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 10/1/2009 71 Male 176 lb 9/23/2011 Consumer Brazil
Primary
Secondary
Concomitant
Injection Site Necrosis Other Serious 8/1/2011 47 Female 315 lb 10/12/2011 Physician United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 72 Female 176 lb 10/13/2011 Physician Brazil
Primary
Secondary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 3/16/2011 62 Male 176 lb 10/18/2011 Denmark
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/1/2009 71 Male 176 lb 12/5/2011 Consumer Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 72 Female 176 lb 12/15/2011 Physician Brazil
Primary
Secondary
Concomitant
Poisoning Death 30 Male 12/22/2011 Physician United States
Primary
Secondary
Chronic Sinusitis Hospitalization 1/1/1998 36 Female 172 lb 12/29/2011 Consumer United States
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 68 Male 12/20/2011 Other Health Professional United States
Primary
Concomitant
Exostosis Other Serious 1/1/1998 36 Female 172 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Application Site Exfoliation Other Serious Female 150 lb 1/10/2012 Consumer Brazil
Primary
Concomitant
Abdominal Distension Other Serious 1/1/2012 68 Female 1/18/2012 Consumer Brazil
Primary
Concomitant
Application Site Exfoliation Other Serious Female 150 lb 1/20/2012 Consumer Brazil
Primary
Concomitant
Arrhythmia Hospitalization 8/1/2010 69 Female 181 lb 1/24/2012 Consumer Brazil
Primary
Secondary
Concomitant
Arthritis Disability 1/1/2009 63 Female 3/1/2012 Lawyer United States
Primary
Concomitant
Mass Hospitalization 12/14/2011 85 Male 175 lb 3/8/2012 Consumer Canada
Primary
Concomitant
Osteomyelitis Acute Other Serious 68 Female 3/8/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Arthralgia Hospitalization 1/12/2012 47 Male 228 lb 3/8/2012 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 2/23/2012 74 Male 175 lb 3/13/2012 Other Health Professional Canada
Primary
Concomitant
Cardiovascular Disorder Other Serious Male 386 lb 3/16/2012 Other Health Professional United States
Primary
Concomitant
Cholecystitis Acute Hospitalization 7/28/2010 51 Male 234 lb 3/16/2012 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 2/1/2012 56 Female 220 lb 3/16/2012 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 10/21/2010 58 Female 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2011 73 Female 146 lb 3/19/2012 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 1/1/2012 69 Female 273 lb 3/20/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious Female 4/3/2012 Physician United States
Primary
Concomitant
Aortic Valve Stenosis Hospitalization 11/6/2008 57 Female 148 lb 4/13/2012 Consumer Brazil
Primary
Concomitant
Multi-organ Failure Death 10/30/2011 68 Male 5/16/2012 Other Health Professional Denmark
Primary
Concomitant
Thyroid Disorder Hospitalization 11/6/2008 57 Female 148 lb 5/23/2012 Consumer Brazil
Primary
Concomitant
Agitation Life Threatening 5/21/2012 58 Female 192 lb 6/2/2012 Physician Latvia
Primary
Concomitant
Fatigue Hospitalization 85 Female 5/31/2012 Physician Denmark
Primary
Secondary
Concomitant
Lactic Acidosis Death 10/30/2011 68 Male 5/31/2012 Other Health Professional Norway
Primary
Concomitant
Back Pain Death 1/1/2011 75 Male 176 lb 6/8/2012 Physician United States
Primary
Concomitant
Gastritis 4/1/2012 53 Female 6/26/2012 Consumer Brazil
Primary
Secondary
Concomitant
Intestinal Dilatation Hospitalization 69 Male 6/25/2012 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 11/15/2011 58 Male 190 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 11/15/2011 58 Male 190 lb 4/2/2012 Physician United States
Primary
Secondary
Concomitant
Atrial Flutter Other Serious Male 220 lb 7/3/2012 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Death 3/22/2012 61 Male 245 lb 7/18/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Extremity 66 Female 7/18/2012 Consumer United States
Primary
Concomitant
Dysgeusia 62 Male 240 lb 7/18/2012 Physician United States
Primary
Concomitant
International Normalised Ratio Abnormal 11/13/2004 45 Female 170 lb 7/18/2012 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 3/1/2012 86 Female 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 5/10/2011 68 Female 7/18/2012 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 7/18/2012 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 4/1/2010 7/18/2012 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/22/2012 61 Male 273 lb 7/18/2012 Physician Germany
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 11/1/2011 56 Male 7/18/2012 Physician Germany
Primary
Secondary
Concomitant
Foot Deformity Other Serious 58 Female 115 lb 7/18/2012 Other Health Professional Australia
Primary
Concomitant
Abdominal Pain Hospitalization 5/14/2012 54 Female 146 lb 7/19/2012 Physician United States
Primary
Secondary
Concomitant
Death Death Female 7/19/2012 Physician Australia
Primary
Concomitant
Joint Swelling 5/8/2011 72 Male 7/19/2012 Consumer United States
Primary
Concomitant
Aortic Valve Stenosis Other Serious 11/6/2008 57 Female 148 lb 7/20/2012 Consumer Brazil
Primary
Concomitant
Death Death Female 7/19/2012 Pharmacist United States
Primary
Concomitant
Rash Generalised 7/1/2011 69 Female 200 lb 7/20/2012 Other Health Professional United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Other Serious Female 7/20/2012 Consumer United States
Primary
Concomitant
Dry Skin Life Threatening 4/27/2012 82 Female 7/23/2012 Other Health Professional Canada
Primary
Concomitant
Interacting
Dyspnoea Hospitalization 1/24/2011 77 Male 207 lb 7/24/2012 Physician Germany
Primary
Concomitant
Myalgia Hospitalization 3/24/2012 66 Male 7/24/2012 Physician Italy
Primary
Concomitant
Dyspnoea Hospitalization 6/1/2012 85 Male 7/24/2012 Consumer United States
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/22/2012 61 Male 273 lb 7/25/2012 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious Male 7/25/2012 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 69 Female 291 lb 7/25/2012 Pharmacist Canada
Primary
Concomitant
Dyspnoea Hospitalization 1/24/2011 77 Male 207 lb 7/25/2012 Physician Germany
Primary
Concomitant
Fatigue Hospitalization 5/1/2012 41 Female 175 lb 7/25/2012 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization Male 7/26/2012 Physician United States
Primary
Concomitant
Leukoplakia Oral 7/17/2012 Male 7/26/2012 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious Male 7/27/2012 Physician United States
Primary
Concomitant
Hypertension Other Serious 4/1/2012 58 Female 246 lb 7/31/2012 Physician United States
Primary
Concomitant
Extrasystoles Other Serious 6/1/2012 47 Male 8/2/2012 Physician Bulgaria
Primary
Concomitant
Tongue Disorder 1/1/2011 85 Female 7/31/2012 Consumer United States
Primary
Concomitant
Laceration Hospitalization 1/1/2012 54 Male 197 lb 8/9/2012 Consumer Brazil
Primary
Concomitant
Injection Site Haematoma Other Serious 60 Female 212 lb 8/13/2012 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/14/2011 8/16/2012 Other Health Professional Germany
Primary
Concomitant

Drug Data