Metformin Hcl combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 6/16/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2005 55 Male 9/17/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 9/11/2006 59 Male 10/24/2006 United States
Primary
Concomitant
Vascular Calcification Other Serious 11/28/2006 53 Female 161 lb 12/20/2006 Physician United States
Primary
Concomitant
Respiratory Tract Congestion 1/1/2006 58 Female 235 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/20/2007 Male 6/20/2007 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/1/2006 64 Male 7/14/2007 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/1/2006 64 Male 7/14/2007 Other Health Professional United States
Primary
Concomitant
Urethral Obstruction Other Serious 7/2/2007 63 Male 8/23/2007 United States
Primary
Concomitant
Swelling Other Serious 6/6/2007 76 Female 9/6/2007 Physician United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/1/2006 64 Male 9/7/2007 United States
Primary
Concomitant
Urethral Obstruction Other Serious 7/2/2007 63 Male 9/20/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/1/2007 67 Male 1/15/2008 Physician United States
Primary
Concomitant
Wound Hospitalization 12/15/2007 71 Female 2/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/1/2008 62 Male 289 lb 2/27/2008 United Kingdom
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 67 Male 256 lb 7/30/2008 Pharmacist United States
Primary
Secondary
Concomitant
Tracheo-oesophageal Fistula Other Serious 67 Male 8/11/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2007 Male 8/11/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 Male 8/11/2008 United States
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious 7/6/2004 Male 9/4/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/1/2007 Male 9/25/2008 Physician Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 Male 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 Male 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 11/23/2008 Female 2/10/2009 Physician United States
Primary
Concomitant
Cardiac Arrest Other Serious 11/23/2008 Female 3/19/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 Male 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 11/23/2008 Female 4/14/2009 Physician United States
Primary
Concomitant
Pain Other Serious 12/1/2005 Female 4/30/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious 3/23/2009 Male 5/27/2009 Physician United States
Primary
Concomitant
Vomiting 12/1/2008 68 Female 121 lb 6/17/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 4/11/2009 Female 6/23/2009 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/23/2009 Male 6/24/2009 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2009 67 Male 8/21/2009 Other Health Professional Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 Male 233 lb 9/1/2009 Consumer Brazil
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 Male 233 lb 9/2/2009 Consumer Brazil
Primary
Secondary
Concomitant
Nausea 9/6/2009 66 Female 9/24/2009 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 11/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/14/2007 Male 188 lb 11/20/2009 Physician New Zealand
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 11/18/2009 Male 183 lb 12/21/2009 Germany
Primary
Secondary
Concomitant
Pain Hospitalization 10/21/2009 Male 194 lb 1/22/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 70 Male 95 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Vein Occlusion Disability 12/22/2009 64 Female 161 lb 2/3/2010 Physician France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/7/2004 Female 3/12/2010 United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/15/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/24/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/18/2008 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/20/2003 61 Female 203 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Tumour Flare Other Serious 1/8/2010 61 Male 4/19/2010 Physician United States
Primary
Concomitant
Wound Necrosis Other Serious Male 4/20/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/18/2008 54 Female 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 67 Male 5/4/2010 Other Health Professional United States
Primary
Concomitant
Walking Aid User Other Serious 2/2/2004 75 Male 5/4/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/18/2008 54 Female 6/9/2010 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 3/1/2002 50 Male 7/2/2010 United States
Primary
Concomitant
Death Death Female 123 lb 7/6/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2010 82 Male 7/6/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death Female 123 lb 7/9/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 4/22/2010 73 Male 7/12/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 7/14/2010 United States
Primary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 7/15/2010 United States
Primary
Concomitant
Pollakiuria Hospitalization 4/21/2010 83 Male 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 10/21/2009 73 Male 194 lb 7/22/2010 Physician United States
Primary
Concomitant
Tooth Loss Other Serious Male 7/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/26/2010 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 7/1/2010 79 Female 125 lb 7/28/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 7/30/2010 United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 4/21/2010 83 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/6/2010 United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/13/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 8/13/2010 United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 7/30/2010 57 Male 8/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/21/2010 74 Male 8/20/2010 Other Health Professional Netherlands
Primary
Concomitant
Weight Decreased Other Serious 10/11/2004 70 Male 212 lb 8/23/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 9/8/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/5/2010 64 Male 10/5/2010 Pharmacist Netherlands
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 10/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 10/19/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/18/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 12/13/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Oral Mucosal Erythema Hospitalization 68 Male 1/24/2011 Other Health Professional Japan
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 1/28/2005 44 Male 437 lb 1/24/2011 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/7/2004 47 Female 1/26/2011 Lawyer United States
Primary
Concomitant
Syncope Life Threatening 12/21/2010 70 Male 174 lb 2/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 11/10/2010 70 Male 2/7/2011 Pharmacist Spain
Primary
Concomitant
Myalgia Other Serious 1/1/2005 63 Male 177 lb 2/7/2011 United States
Primary
Secondary
Concomitant
Multiple Myeloma Life Threatening 12/21/2010 70 Male 174 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 12/21/2010 70 Male 174 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 9/9/2010 58 Female 163 lb 2/23/2011 Physician Japan
Primary
Concomitant
Diarrhoea Life Threatening 9/9/2010 58 Female 163 lb 3/7/2011 Physician Japan
Primary
Concomitant
Urinary Retention Other Serious 6/1/2006 78 Male 200 lb 3/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 12/9/2002 3/22/2011 Lawyer United States
Primary
Concomitant
Meniscus Lesion Other Serious 1/1/2007 50 Male 3/29/2011 Physician United States
Primary
Concomitant
Gingival Bleeding Disability 1/1/2003 46 Male 3/29/2011 Lawyer United States
Primary
Concomitant
Gout Hospitalization 12/10/2010 80 Female 4/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bladder Discomfort Other Serious 1/1/2007 50 Male 4/8/2011 Physician United States
Primary
Concomitant
Muscle Strain Other Serious 7/6/2009 64 Male 4/19/2011 Other Health Professional United States
Primary
Concomitant
Asteatosis Hospitalization 1/1/2005 63 Male 177 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 3/28/2011 74 Male 195 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 3/30/2011 67 Male 5/12/2011 Netherlands
Primary
Concomitant
Neoplasm Malignant Other Serious 6/1/2006 78 Male 200 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Colitis Hospitalization 4/14/2011 84 Female 5/17/2011 Other Health Professional United States
Primary
Concomitant
Colitis Other Serious 12/9/2002 5/19/2011 Consumer United States
Primary
Concomitant
Injection Site Warmth 5/1/2010 72 Male 184 lb 3/28/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 3/18/2011 61 Male 230 lb 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Other Serious 1/1/2007 65 Male 5/27/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2010 76 Male 5/31/2011 Physician United States
Primary
Secondary
Concomitant
Patellofemoral Pain Syndrome Other Serious 2/13/2004 47 Male 6/1/2011 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 159 lb 6/2/2011 Consumer Brazil
Primary
Concomitant
Urinary Retention Hospitalization 12/5/2010 71 Female 148 lb 6/2/2011 Other Health Professional Japan
Primary
Concomitant
Hordeolum Hospitalization 1/7/2004 47 Female 6/6/2011 Physician United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 184 lb 6/6/2011 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 5/1/2011 78 Male 6/10/2011 Consumer Netherlands
Primary
Concomitant
Death Death 7/7/2004 62 Male 162 lb 6/10/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/9/2002 6/13/2011 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/23/2005 70 Female 6/11/2011 Canada
Primary
Concomitant
Fatigue Other Serious 1/1/2006 42 Female 6/15/2011 Physician United States
Primary
Concomitant
Dyskinesia Hospitalization 3/14/2011 53 Male 231 lb 6/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/13/2011 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaw Fracture Other Serious 6/16/2008 60 Female 101 lb 6/20/2011 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 5/4/2011 62 Female 190 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 3/28/2011 74 Male 195 lb 6/23/2011 Physician United States
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 6/1/2006 47 Female 6/23/2011 Other Health Professional United States
Primary
Concomitant
Abscess Oral Hospitalization 6/16/2008 60 Female 101 lb 6/27/2011 Other Health Professional Japan
Primary
Concomitant
Bone Marrow Oedema Other Serious Female 6/27/2011 Other Health Professional United States
Primary
Concomitant
Bone Disorder Hospitalization 6/5/2008 69 Male 128 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 5/5/2011 59 Female 6/28/2011 Physician Germany
Primary
Secondary
Concomitant
Osteosclerosis Hospitalization 1/1/2005 63 Male 216 lb 6/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxoplasma Serology Positive Hospitalization 5/7/2005 58 Male 174 lb 6/29/2011 United States
Primary
Secondary
Concomitant
Abdominal Distension Other Serious 4/1/2002 38 Female 6/30/2011 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/7/2004 60 Male 7/5/2011 Consumer United States
Primary
Concomitant
Hypersomnia Hospitalization 6/25/2011 73 Male 7/6/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious Male 7/8/2011 Pharmacist Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Life Threatening 4/15/2011 Female 7/12/2011 Physician Cyprus
Primary
Concomitant
Pneumonia Other Serious 12/9/2002 7/14/2011 Lawyer United States
Primary
Concomitant

Drug Data