Metformin Hcl combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Refusal Of Treatment By Patient Hospitalization 85 Female 1/5/2006 Physician United States
Primary
Secondary
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2005 85 Female 1/26/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 11/2/2005 71 Male 1/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Localised Infection Hospitalization 12/31/2005 71 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oliguria Other Serious 12/7/2005 61 Male 291 lb 2/21/2006 Physician Canada
Primary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/18/2007 Male 135 lb 4/13/2007 United States
Primary
Secondary
Concomitant
Somnolence 11/14/2006 65 Female 170 lb 1/12/2007 Consumer United States
Primary
Concomitant
Cardioversion Other Serious 3/1/2006 Male 143 lb 5/11/2007 Physician Australia
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2006 60 Male 5/13/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/19/2007 78 5/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 84 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 78 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 66 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Atrial Fibrillation Hospitalization 6/15/2007 Male 203 lb 8/22/2007 United Kingdom
Primary
Concomitant
Testicular Swelling Life Threatening 1/1/1999 59 Male 9/4/2007 Consumer United States
Primary
Concomitant
Posturing Life Threatening 6/21/2007 68 Male 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 181 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Parosmia Hospitalization 12/1/2008 74 Female 1/9/2009 Consumer
Primary
Concomitant
Haemarthrosis Hospitalization 1/1/2009 Male 194 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant
Upper Limb Fracture Other Serious Female 1/23/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 51 Female 4/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 6/1/2008 76 Female 4/29/2009 Consumer United States
Primary
Concomitant
Frequent Bowel Movements 9/2/2008 Male 4/30/2009 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/1/2005 65 Female 250 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/1/2008 Female 270 lb 4/29/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/17/2002 65 Female 164 lb 6/3/2009 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 6/2/2009 Female 160 lb 6/25/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/1/2009 Male 190 lb 8/9/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Life Threatening 6/9/2009 68 Male 229 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 8/11/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/12/2009 Consumer United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/22/2005 Male 8/21/2009 Physician Canada
Primary
Concomitant
Erythema 4/8/2009 Male 8/22/2009 United States
Primary
Concomitant
Sensory Disturbance Female 8/22/2009 United States
Primary
Concomitant
Multiple Myeloma Death 3/17/2009 Male 8/24/2009 Pharmacist United States
Primary
Concomitant
Nausea 3/1/2008 Female 270 lb 8/20/2009 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/22/2005 Male 8/28/2009 Physician Canada
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/28/2009 Portugal
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 66 Male 802 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Surgery Death Female 9/11/2009 United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Vomiting Required Intervention 7/3/2009 53 Female 131 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Visual Impairment Hospitalization 1/1/2009 52 Male 370 lb 9/28/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 81 Male 136 lb 10/27/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 39 Female 344 lb 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 73 Female 331 lb 1/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 7/23/2009 Female 1/13/2010 Physician United States
Primary
Concomitant
Hyperkalaemia Life Threatening 73 Female 1/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 73 Female 331 lb 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 74 Male 6/2/2010 Other Health Professional Italy
Primary
Concomitant
Interacting
Psoriasis Hospitalization 4/1/2010 41 Male 310 lb 6/14/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 74 Male 6/15/2010
Primary
Secondary
Renal Failure Other Serious 3/1/2008 74 Male 6/15/2010 Lawyer United States
Primary
Concomitant
Haematuria Hospitalization 9/1/2008 78 Male 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 74 Male 6/16/2010 Other Health Professional Italy
Primary
Concomitant
Interacting
Nausea 7/28/2008 48 Male 351 lb 6/24/2010 Consumer United States
Primary
Concomitant
Atrial Fibrillation 1/1/2007 66 Female 230 lb 6/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 4/1/2007 68 Male 160 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 3/4/2010 66 Male 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged 10/13/2008 66 Male 265 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Death Death 6/9/2010 51 Female 264 lb 6/30/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 74 Male 6/22/2010 Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization Female 7/6/2010 Physician United States
Primary
Concomitant
Rash Other Serious 2/4/2010 80 Male 187 lb 7/7/2010 Consumer United States
Primary
Secondary
Concomitant
Hyperhidrosis 1/27/2007 66 Female 172 lb 7/9/2010 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 7/5/2010 52 Female 203 lb 7/22/2010 Other Health Professional Australia
Primary
Concomitant
Rash Pruritic 3/1/1999 57 Male 245 lb 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/4/2010 66 Male 8/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/1984 74 Male 8/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Occlusion Other Serious 1/1/2010 59 Male 185 lb 8/12/2010 Consumer Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/13/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypoxia Hospitalization Male 240 lb 8/13/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/1/2010 59 Male 350 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Hospitalization 6/2/2010 51 Female 264 lb 8/25/2010 Physician United States
Primary
Concomitant
Hypoxia Hospitalization 8/14/2010 79 Male 240 lb 8/25/2010 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 4/4/2010 Female 183 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 10/19/2010 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 7/31/2010 73 Male 10/20/2010 Other Health Professional Sweden
Primary
Concomitant
Thrombosis Other Serious 61 Male 389 lb 10/20/2010 Pharmacist United States
Primary
Concomitant
Lung Transplant Hospitalization 59 Male 195 lb 10/20/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/9/2010 65 Female 11/2/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 70 Male 10/21/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 11/12/2009 56 Female 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 53 Male 11/10/2010 Physician United States
Primary
Concomitant
Infection Hospitalization 10/17/2010 67 Female 11/14/2010 Consumer Canada
Primary
Concomitant
Rhinitis Hospitalization 10/26/2009 58 Male 205 lb 12/1/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/4/2010 72 Female 181 lb 12/6/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/1/2010 77 Female 110 lb 12/15/2010 Physician Japan
Primary
Secondary
Concomitant
Limb Asymmetry Hospitalization 1/1/2010 74 Female 158 lb 1/5/2011 Consumer United States
Primary
Concomitant
Arthralgia 9/1/2010 44 Female 305 lb 1/6/2011 Consumer United States
Primary
Concomitant
Tendonitis Other Serious 5/2/2000 43 Female 270 lb 1/17/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 11/1/2010 77 Female 110 lb 1/21/2011 Physician Japan
Primary
Concomitant
Pneumonia Death 9/1/2009 76 Male 104 lb 1/24/2011 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious Male 1/24/2011 Physician Switzerland
Primary
Concomitant
Cardio-respiratory Arrest Death 78 Female 1/5/2011 United States
Primary
Concomitant
Pneumonia Hospitalization 41 Female 201 lb 1/28/2011 Consumer United States
Primary
Concomitant
Eye Disorder Other Serious 1/1/2011 77 Female 2/2/2011 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Death 9/1/2009 76 Male 104 lb 2/2/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2011 64 Female 2/9/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2011 77 Female 2/10/2011 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 1/1/2006 17 Female 243 lb 2/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms 1/1/2010 43 Female 3/4/2011 Consumer United States
Primary
Concomitant
Arthralgia 11/1/2010 44 Female 300 lb 3/7/2011 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 5/24/2010 59 Male 206 lb 3/3/2011 Physician United States
Primary
Concomitant
Atrial Flutter Hospitalization 2/1/2011 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 7/30/2010 76 Male 251 lb 3/29/2011 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 2/1/2011 4/17/2011 Physician Japan
Primary
Secondary
Concomitant
Burning Sensation Disability 2/18/2011 73 Female 4/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypertensive Crisis Life Threatening 2/18/2011 73 Male 194 lb 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 3/25/2011 71 Male 240 lb 5/11/2011 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 50 Female 7/1/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 6/30/2011 8/3/2011 Pharmacist Australia
Primary
Concomitant
Pancreatitis Relapsing Other Serious 11/1/2006 56 Male 250 lb 8/3/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Other Serious 4/18/2011 88 Male 209 lb 8/4/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/15/2011 71 Female 170 lb 8/4/2011 Physician United States
Primary
Concomitant
Cardiac Pacemaker Insertion Hospitalization 6/10/2011 81 Male 249 lb 8/4/2011 Physician Canada
Primary
Concomitant
Hypotension Hospitalization 4/21/2011 65 Male 236 lb 8/4/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/18/2011 65 Male 190 lb 8/4/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 12/4/2010 73 Female 185 lb 8/4/2011 Physician United States
Primary
Concomitant
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/11/2011 Lawyer United States
Primary
Concomitant
Low Cardiac Output Syndrome Death 4/27/2011 68 Male 161 lb 9/16/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Death 4/27/2011 68 Male 161 lb 9/19/2011 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 62 Female 9/28/2011 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Pneumonia Death 4/27/2011 68 Male 161 lb 10/24/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/9/2011 65 Female 200 lb 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gout Other Serious Male 11/1/2011 United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 1/1/2011 74 Female 12/21/2011 Physician Canada
Primary
Concomitant
Drug Ineffective 12/14/2011 Male 1/5/2012 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 1/20/2012 72 Male 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Hallucination Other Serious 2/22/2012 75 Male 3/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Hallucination Other Serious 2/22/2012 75 Male 4/18/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 4/11/2012 53 Male 181 lb 5/4/2012 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 12/13/2011 60 Male 247 lb 6/8/2012 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 6/8/2012 Other Health Professional United States
Primary
Concomitant
Emphysema Other Serious 65 Male 218 lb 6/11/2012 Consumer United States
Primary
Concomitant
Oliguria Hospitalization 73 Female 9/14/2012 Consumer De
Primary
Concomitant
Sepsis Life Threatening 72 Female 10/19/2012 Consumer De
Primary
Concomitant
Testicular Swelling Life Threatening 1999 55 Male 10/22/2012 Physician Us
Primary
Concomitant
Plasma Cell Myeloma Death 11/19/2012 Female 203 lb 3/25/2013 Other Health Professional Us
Primary
Concomitant
Plasma Cell Myeloma Death 12/2012 Male 250 lb 3/15/2013 Physician Us
Primary
Concomitant
Glioblastoma Hospitalization 2/18/2013 46 Male 228 lb 3/11/2013 Physician Us
Primary
Concomitant

Drug Data