Metformin Hcl combined with Vitamin E

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Secretion Hospitalization 12/3/2005 65 Male 1/6/2006 Physician United States
Primary
Concomitant
Rash Other Serious 1/1/2005 25 Female 2/22/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 200 lb 2/17/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 10/7/2005 76 Male 160 lb 2/28/2006 United States
Primary
Concomitant
Paraesthesia Other Serious 3/23/2006 62 Female 125 lb 8/23/2006 Physician United States
Primary
Concomitant
Endometrial Cancer Stage Ii Hospitalization 5/2/2006 64 Female 9/5/2006 Physician United States
Primary
Concomitant
Weight Decreased 5/6/2006 63 Male 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Increased 5/1/2006 61 Female 7/19/2006 Consumer United States
Primary
Concomitant
Nervousness Hospitalization 8/1/2006 58 Female 222 lb 9/19/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Male 239 lb 10/13/2006 United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Joint Swelling Other Serious 10/16/2006 61 Male 225 lb 11/16/2006 United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 10/16/2006 61 Male 255 lb 12/19/2006 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/28/2005 60 Male 11/6/2006 Physician United States
Primary
Concomitant
Weight Fluctuation Hospitalization 67 Male 255 lb 1/18/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2005 57 Male 287 lb 2/1/2007 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 11/24/2006 78 Male 180 lb 3/9/2007 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/1/2005 67 Male 8/28/2006 Consumer United States
Primary
Concomitant
Pyrexia 1/1/2006 51 Female 1/12/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Female 140 lb 4/19/2007 Consumer United States
Primary
Concomitant
Septic Shock Other Serious 1/1/2007 68 Female 161 lb 4/18/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 4/1/2006 32 Male 274 lb 1/12/2007 Consumer United States
Primary
Concomitant
Urethral Pain Other Serious 11/28/2006 53 Female 150 lb 4/17/2007 Physician United States
Primary
Concomitant
Humerus Fracture Required Intervention 12/4/2006 73 Male 150 lb 4/23/2007 Physician United States
Primary
Concomitant
Dyskinesia Other Serious 2/9/2007 43 Female 181 lb 5/30/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Required Intervention 12/3/2006 73 Male 150 lb 5/25/2007 Physician United States
Primary
Concomitant
Sinusitis 11/1/2006 63 236 lb 5/17/2007 Physician United States
Primary
Concomitant
Weight Decreased 11/1/2006 81 Female 180 lb 4/10/2007 Consumer United States
Primary
Concomitant
Muscular Weakness 78 Female 155 lb 6/25/2007 United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 Female 216 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 1/1/2007 Male 234 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2006 59 Female 9/6/2007 Consumer United States
Primary
Concomitant
Insomnia 74 Female 11/13/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2005 57 Male 287 lb 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 9/1/2007 Female 11/27/2007 United States
Primary
Concomitant
Hallucination, Auditory Other Serious 9/30/2007 67 Female 210 lb 12/3/2007 Consumer United States
Primary
Concomitant
Hallucination, Auditory Other Serious 9/30/2007 67 Female 210 lb 12/3/2007 Consumer United States
Primary
Concomitant
Gout 65 Male 190 lb 12/17/2007 United States
Primary
Concomitant
Speech Disorder Hospitalization 11/1/2007 Male 12/12/2007 Consumer United States
Primary
Concomitant
Death Death 12/23/2007 Female 153 lb 1/3/2008 Physician Canada
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/28/2005 Male 182 lb 1/11/2008 Consumer United States
Primary
Concomitant
Death Death 12/23/2007 Female 153 lb 1/18/2008 Physician Canada
Primary
Secondary
Concomitant
Convulsion Other Serious 82 Female 2/7/2008 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 82 Female 2/8/2008 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Death 12/23/2007 Female 153 lb 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
Rash Vesicular Other Serious Female 180 lb 2/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/15/2003 Male 267 lb 2/21/2008 Australia
Primary
Secondary
Concomitant
Muscle Spasms 10/22/2007 55 Male 197 lb 11/8/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2008 Male 240 lb 3/6/2008 United States
Primary
Concomitant
Faeces Discoloured 11/29/2007 73 Female 161 lb 3/9/2008 Consumer United States
Primary
Concomitant
Oedema Other Serious 60 Male 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Wrong Drug Administered Life Threatening 12/28/2007 Female 172 lb 4/10/2008 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2007 57 Female 172 lb 4/22/2008 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 71 Female 4/30/2008 Consumer Canada
Primary
Concomitant
Restlessness Other Serious 58 Female 5/20/2008 Consumer India
Primary
Concomitant
Faeces Discoloured 11/29/2007 73 Female 161 lb 5/29/2008 Consumer United States
Primary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Required Intervention 2/1/2000 71 Male 155 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 7/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/29/2008 Male 7/29/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/29/2008 Male 7/30/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder 5/10/2008 Female 225 lb 8/27/2008 Consumer United States
Primary
Concomitant
Hot Flush 1/1/2006 Female 8/27/2008 United States
Primary
Concomitant
Oedema Hospitalization 10/1/2006 74 Male 261 lb 8/29/2008 Consumer United States
Primary
Concomitant
Poor Quality Sleep 7/7/2008 Male 228 lb 8/29/2008
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/21/2008 Female 120 lb 9/5/2008 Physician United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/21/2005 57 Female 194 lb 9/19/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Pain 76 Female 130 lb 10/7/2008 Consumer United States
Primary
Concomitant
Death Death Male 212 lb 10/10/2008 Consumer United States
Primary
Concomitant
Intestinal Obstruction Other Serious 3/1/2008 75 Female 10/30/2008 Consumer United States
Primary
Concomitant
Pain Of Skin Hospitalization 1/1/2008 Male 11/6/2008 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Male 212 lb 11/14/2008 Other Health Professional United States
Primary
Concomitant
Vaginal Discharge Hospitalization 1/1/2008 Female 11/19/2008 Consumer United States
Primary
Concomitant
Trigger Finger Other Serious 66 Female 240 lb 11/25/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 280 lb 11/24/2008 Physician United States
Primary
Concomitant
Myalgia 8/6/2008 Female 172 lb 11/26/2008 United States
Primary
Concomitant
Blood Urine Present 4/11/2008 61 Male 195 lb 12/17/2008 Consumer United States
Primary
Concomitant
Muscular Weakness 7/14/2008 78 Male 195 lb 12/10/2008 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 12/26/2008 58 Male 300 lb 12/31/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/1/2007 Male 12/31/2008 Consumer United States
Primary
Concomitant
Night Sweats Other Serious 7/1/2007 70 Female 160 lb 1/7/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 280 lb 3/2/2009 Physician United States
Primary
Concomitant
Chest Discomfort Other Serious 5/17/2008 Female 120 lb 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Pitting Oedema Other Serious 1/1/2008 75 Male 3/30/2009 Other Health Professional United States
Primary
Concomitant
Palpitations 1/1/2009 Male 4/2/2009 Physician
Primary
Concomitant
Vision Blurred Other Serious 3/1/2007 Male 4/3/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 12/26/2008 58 Male 300 lb 4/9/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/1/2007 Male 4/24/2009 Consumer United States
Primary
Concomitant
Gastroenteritis Viral Hospitalization 4/21/2009 60 Male 207 lb 5/20/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 73 Male 181 lb 6/23/2009 Consumer Brazil
Primary
Secondary
Concomitant
Surgery Death 64 Male 217 lb 6/18/2009 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 7/6/1998 47 Male 258 lb 7/10/2009 United States
Primary
Concomitant
Urticaria 6/1/2009 76 Male 152 lb 7/13/2009 Consumer United States
Primary
Concomitant
Nausea 90 Male 7/14/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria 6/1/2009 76 Male 152 lb 7/14/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 66 Female 7/15/2009 United States
Primary
Concomitant
Weight Increased 7/9/2008 69 Female 220 lb 7/21/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 66 Female 8/6/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 8/16/2009 Lawyer United States
Primary
Concomitant
Feeling Abnormal Other Serious 40 Female 196 lb 8/12/2009 United States
Primary
Concomitant
Skin Burning Sensation 4/13/2009 Female 8/22/2009 United States
Primary
Concomitant
Pruritus 5/24/2009 Male 8/22/2009 United States
Primary
Concomitant
Abdominal Discomfort 6/1/2009 43 Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 6/12/2009 Female 8/22/2009 United States
Primary
Concomitant
Paraesthesia Female 157 lb 8/23/2009 United States
Primary
Concomitant
Uterine Polyp Hospitalization 61 Female 8/25/2009 United States
Primary
Concomitant
Influenza Like Illness Other Serious 7/12/2009 32 Female 9/7/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1997 Female 120 lb 9/17/2009 Consumer United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 10/1/2006 74 Male 261 lb 9/22/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Vitreous Floaters Hospitalization 62 Female 10/16/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1997 Female 120 lb 10/26/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 10/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 62 Female 11/4/2009 United States
Primary
Concomitant
Vitreous Floaters Hospitalization 62 Female 11/16/2009 Lawyer United States
Primary
Concomitant
Coronary Artery Disease Death 12/23/2007 Female 153 lb 11/30/2009 Physician Canada
Primary
Secondary
Concomitant
Tremor Other Serious 59 Female 157 lb 12/7/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Vitreous Floaters Hospitalization 62 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Headache Other Serious 12/1/2008 72 Male 185 lb 12/22/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 46 Female 309 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Pubis Fracture Other Serious 8/1/2006 Male 206 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 46 Female 309 lb 3/23/2010 Lawyer United States
Primary
Concomitant
Pallor Other Serious 2/12/2010 Female 201 lb 3/23/2010 Consumer Brazil
Primary
Concomitant
Urticaria Other Serious 48 Female 3/24/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Off Label Use Hospitalization Male 187 lb 5/5/2010 Pharmacist Netherlands
Primary
Concomitant
Oedema Peripheral Hospitalization 1/4/2010 79 Male 5/10/2010 Consumer Italy
Primary
Concomitant
Vomiting Hospitalization 4/5/2010 36 Female 285 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 3/12/2010 74 Female 138 lb 6/9/2010 United States
Primary
Concomitant
Rash Other Serious 2/26/2008 87 Male 151 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 10/29/2009 41 Male 134 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Drug Ineffective 7/27/2007 43 Male 205 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 5/9/2010 68 Female 172 lb 6/20/2010 United States
Primary
Concomitant
Vomiting 11/1/2006 84 Female 140 lb 7/8/2010 Consumer United States
Primary
Concomitant
Wound 12/5/2006 71 Male 272 lb 7/8/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/12/2010 74 Female 138 lb 7/15/2010 United States
Primary
Concomitant
Cough 8/1/2007 57 Male 256 lb 7/15/2010 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2009 67 Female 147 lb 7/19/2010 Consumer United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/10/2008 46 Female 225 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia 7/1/2008 70 Male 198 lb 7/30/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 9/1/2007 72 Female 200 lb 8/2/2010 Consumer United States
Primary
Concomitant
Somnolence 3/18/2008 60 Female 298 lb 8/3/2010 Consumer United States
Primary
Concomitant
Somnolence Female 180 lb 8/3/2010 Consumer United States
Primary
Concomitant

Drug Data