Metformin Hcl combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 5/25/2005 Female 2/24/2006 Physician Germany
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 6/16/2006 United States
Primary
Concomitant
Stomach Discomfort 6/5/2006 65 Female 280 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/6/2006 63 Male 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Increased 5/1/2006 61 Female 7/19/2006 Consumer United States
Primary
Concomitant
Nervousness Hospitalization 8/1/2006 58 Female 222 lb 9/19/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 10/19/2006 Physician United States
Primary
Secondary
Concomitant
Cough 1/1/2006 77 Male 10/30/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2006 54 Female 258 lb 11/9/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2006 64 Female 10/16/2006 Consumer United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Creatinine Renal Clearance Increased 12/1/2005 70 Male 168 lb 2/27/2007 Consumer United States
Primary
Concomitant
Weight Decreased 7/1/2006 71 Male 215 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 225 lb 2/27/2007 United States
Primary
Concomitant
Skin Lesion Other Serious 2/23/2007 Female 200 lb 4/19/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 11/1/2006 74 Female 251 lb 1/12/2007 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 1/1/2007 64 Female 4/24/2007 Physician United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 2/18/2007 66 Female 5/4/2007 Physician Canada
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2006 60 Male 5/13/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Lesion Other Serious 2/23/2007 Female 200 lb 5/16/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2005 68 Male 253 lb 5/25/2007 Physician United States
Primary
Concomitant
Haematochezia Other Serious 12/1/2006 68 Female 170 lb 2/28/2007 United States
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/18/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/22/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 143 lb 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/2/2007 61 Male 198 lb 7/30/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/31/2007 87 Female 249 lb 8/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 11/7/2006 74 Female 260 lb 7/11/2007 Consumer United States
Primary
Concomitant
Multiple Myeloma Other Serious 7/30/2007 Female 157 lb 8/31/2007 United Kingdom
Primary
Concomitant
Syncope Hospitalization 8/13/2007 69 Male 303 lb 9/5/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 9/25/2007 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/1/2007 86 Female 165 lb 10/2/2007 Consumer United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 8/13/2007 Male 303 lb 10/9/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/19/2007 47 Female 10/31/2007 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 11/2/2007 Physician Spain
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/1/2007 Female 11/5/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/8/2007 United States
Primary
Concomitant
Hiatus Hernia Hospitalization 9/13/2007 Female 303 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/21/2007 United States
Primary
Concomitant
Hiatus Hernia Hospitalization 9/13/2007 58 Female 11/30/2007 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 8/1/2007 Male 220 lb 12/11/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 74 Female 12/7/2007 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 9/13/2007 Female 303 lb 12/24/2007 Physician United States
Primary
Secondary
Concomitant
Hiatus Hernia Other Serious 9/13/2007 58 Female 1/10/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/1/2007 Female 1/21/2008 Physician United States
Primary
Concomitant
Multiple Myeloma Other Serious 6/1/2007 Female 157 lb 1/29/2008 United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 10/1/2007 Female 1/25/2008 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization 12/17/2007 Female 185 lb 1/31/2008 Consumer United States
Primary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 200 lb 2/1/2008 Consumer United States
Primary
Concomitant
Melaena Other Serious 9/13/2007 58 Female 2/7/2008 United States
Primary
Concomitant
Pancreatitis Other Serious 1/16/2008 Female 160 lb 2/12/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 2/7/2008 68 Male 3/3/2008 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2006 68 Female 170 lb 3/14/2007 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/1/2008 Female 177 lb 3/11/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/1/2008 Female 177 lb 3/18/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 166 lb 3/20/2008 Consumer United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/4/2008 United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/10/2008 United States
Primary
Concomitant
Pharyngolaryngeal Pain 2/29/2008 Male 4/10/2008 Consumer United States
Primary
Concomitant
Nephrolithiasis 2/1/2006 Female 213 lb 4/10/2008 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 4/18/2008 Consumer United Kingdom
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/18/2008 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 4/22/2008 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 195 lb 4/16/2008 Physician United States
Primary
Concomitant
Spinal Fracture Other Serious 52 Male 4/25/2008 Consumer United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 4/28/2008 United States
Primary
Secondary
Concomitant
Drug Ineffective 2/1/2008 80 Male 218 lb 4/30/2008 United States
Primary
Concomitant
Weight Decreased Other Serious Female 180 lb 5/2/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/2/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/6/2008 United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 5/13/2008 Physician Canada
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 198 lb 5/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 195 lb 5/8/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/15/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 84 Male 5/17/2008 Physician Canada
Primary
Concomitant
Dyspnoea 1/1/2008 83 Male 5/21/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/23/2008 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2008 59 Female 143 lb 5/30/2008 Physician France
Primary
Concomitant
Hypersensitivity Other Serious 4/28/2008 Male 6/5/2008 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea 1/1/2008 83 Male 6/24/2008 Physician United States
Primary
Concomitant
Osteoporosis Hospitalization 3/21/2006 66 Female 170 lb 6/20/2008 Consumer United States
Primary
Concomitant
Fall Hospitalization 3/17/2008 68 Female 170 lb 6/20/2008 Consumer United States
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 7/11/2008 Male 80 lb 7/24/2008 Consumer United States
Primary
Concomitant
Nocturia 4/1/2008 Male 8/8/2008 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 8/4/2008 Female 157 lb 8/17/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Hospitalization 10/1/2006 74 Male 261 lb 8/29/2008 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 8/4/2008 Female 157 lb 8/28/2008 Physician United States
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 1/1/2006 Female 220 lb 9/18/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 9/3/2008 Female 10/7/2008 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Pruritic 10/25/2007 70 Female 184 lb 10/10/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 10/21/2008 Female 206 lb 10/31/2008 United States
Primary
Concomitant
Scotoma Other Serious 7/1/2008 Male 11/3/2008 Pharmacist Canada
Primary
Concomitant
Syncope Other Serious 10/21/2008 Female 206 lb 11/5/2008 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2008 Female 11/1/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 10/21/2008 Female 206 lb 11/14/2008 United States
Primary
Concomitant
Anaemia Other Serious 2/1/2008 Female 11/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 280 lb 11/24/2008 Physician United States
Primary
Concomitant
Weight Fluctuation Other Serious 1/1/2006 Female 220 lb 11/26/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 12/1/2007 Male 196 lb 12/4/2008 Physician United States
Primary
Concomitant
Diarrhoea 79 Female 165 lb 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 1/18/2009 62 Female 2/2/2009 Pharmacist Germany
Primary
Concomitant
Death Death Female 2/3/2009 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 73 Male 280 lb 1/29/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/1/2006 Female 103 lb 2/19/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 280 lb 3/2/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/28/2009 70 Male 201 lb 3/4/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 1/18/2009 62 Female 3/10/2009 Pharmacist Canada
Primary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 3/19/2009 Consumer United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2009 Male 187 lb 3/19/2009 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2008 Male 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 4/3/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 12/1/2008 Male 190 lb 4/15/2009 Physician United States
Primary
Secondary
Concomitant
Weight Control Hospitalization 9/1/2008 Female 4/29/2009 Puerto Rico
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/18/2009 Female 183 lb 5/4/2009 New Zealand
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Other Serious 4/1/2009 62 Female 5/5/2009 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 2/1/2009 Male 5/8/2009 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/15/2009 71 Female 5/14/2009 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/17/2009 64 Female 119 lb 5/20/2009 Physician Canada
Primary
Concomitant
Pneumonitis Hospitalization 4/18/2009 Female 183 lb 5/21/2009 New Zealand
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/1/2008 Female 230 lb 5/19/2009 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2000 Female 5/22/2009 Consumer Australia
Primary
Concomitant
Pulmonary Hypertension Other Serious 10/1/2008 Male 212 lb 5/22/2009 Physician United States
Primary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 5/26/2009 Consumer United Kingdom
Primary
Concomitant
Blood Glucose Increased 4/1/2009 Female 255 lb 5/27/2009 United States
Primary
Concomitant
Feeling Hot 5/1/2009 Male 5/27/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 6/16/2009 Female 220 lb 6/25/2009 Consumer United States
Primary
Concomitant
Crohn's Disease Hospitalization 4/23/2009 53 Female 7/6/2009 Other Health Professional Canada
Primary
Concomitant
Death Death 7/1/2009 Female 7/9/2009 Consumer United States
Primary
Concomitant
Urticaria 6/1/2009 76 Male 152 lb 7/13/2009 Consumer United States
Primary
Concomitant
Urticaria 6/1/2009 76 Male 152 lb 7/14/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/4/2008 Female 157 lb 7/15/2009 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Disability 6/17/2009 Female 218 lb 7/22/2009 Physician United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/1/2009 Female 7/23/2009 Consumer United States
Primary
Concomitant
Malaise 6/7/2008 71 Male 7/23/2009 Consumer United States
Primary
Concomitant
Anaemia Other Serious 4/1/2008 69 Female 7/23/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/24/2009 Canada
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 4/23/2009 53 Female 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Pruritus Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 180 lb 8/22/2009 United States
Primary
Concomitant
Rash 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/4/2008 Female 157 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 6/16/2009 Female 220 lb 8/27/2009 Physician United States
Primary
Concomitant

Drug Data