Metformin Hcl combined with Tramadol Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Localised Infection Hospitalization 12/31/2005 71 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 12/28/2005 58 Male 418 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 12/13/2005 81 Male 258 lb 1/20/2006 United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/5/2006 65 Female 209 lb 2/22/2006 Physician Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/1/2004 Male 4/3/2006 Physician New Zealand
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/9/2006 54 Male 300 lb 4/18/2006 Consumer United States
Primary
Concomitant
Swelling Disability 46 Male 254 lb 6/19/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Hypoglycaemia Other Serious 8/28/2006 73 Female 210 lb 10/13/2006 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 8/28/2006 73 Female 210 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Disability 3/1/2003 47 Male 10/25/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 8/2/2006 53 Male 120 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Disability 3/1/2003 47 Male 11/1/2006 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 9/9/2006 60 Male 275 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Breast Swelling 1/1/2006 73 Male 12/28/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2006 Female 1/9/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/11/2004 46 Female 1/11/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vertigo Hospitalization 4/21/2006 75 Female 196 lb 9/26/2006 United States
Primary
Concomitant
Vitreous Haemorrhage Disability 3/1/2003 47 Male 1/15/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 2/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Rash Other Serious 3/1/2005 65 Female 170 lb 6/14/2005 United States
Primary
Concomitant
Syncope Hospitalization 1/8/2007 63 Male 223 lb 2/16/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/8/2007 63 Male 223 lb 2/23/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 3/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 3/8/2007 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Death 12/4/2006 59 Female 3/9/2007 Pharmacist Malaysia
Primary
Concomitant
Septic Shock Hospitalization 67 Female 112 lb 3/9/2007 Physician Korea, Republic Of
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/13/2006 67 Female 112 lb 3/21/2007 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2007 46 Male 243 lb 4/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Myalgia 11/8/2006 52 Male 1/12/2007 Consumer United States
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 4/27/2007 Consumer United States
Primary
Concomitant
Oesophageal Ulcer 66 Female 190 lb 4/30/2007 United States
Primary
Concomitant
Skin Ulcer Life Threatening 4/30/2007 Consumer United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 2/23/2007 68 Female 251 lb 5/2/2007 Physician United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Disability 3/1/2003 47 Male 5/4/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 10/19/2006 65 Female 1/25/2007 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12/1/2006 Male 216 lb 5/15/2007 Pharmacist France
Primary
Secondary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Somnolence Hospitalization 7/31/2006 1 Male 5/17/2007 Other Health Professional United States
Primary
Secondary
Hyperaesthesia Hospitalization 62 Male 159 lb 5/24/2007 Belgium
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 61 Female 183 lb 6/1/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/28/2007 Female 265 lb 6/12/2007 United States
Primary
Secondary
Concomitant
Hypersomnia Other Serious 1/13/2007 77 Female 260 lb 7/2/2007 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 200 lb 7/13/2007 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 7/5/2007 77 Male 7/18/2007 Consumer Australia
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 6/25/2007 67 Male 7/24/2007 Physician Guatemala
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/9/2003 59 Male 7/26/2007 Consumer United States
Primary
Concomitant
Hypothyroidism Hospitalization 3/3/2005 58 Female 8/3/2007 United States
Primary
Concomitant
Drug Interaction Hospitalization 73 Male 8/13/2007
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12/1/2006 Male 216 lb 8/15/2007 Pharmacist France
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 1/1/2007 Male 234 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12/1/2006 Male 216 lb 8/20/2007 Pharmacist France
Primary
Secondary
Concomitant
Femur Fracture Other Serious 4/1/2007 65 Female 8/20/2007 Physician Argentina
Primary
Concomitant
Tremor Hospitalization 8/1/2006 55 Female 8/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious Female 8/24/2007 Physician Ireland
Primary
Concomitant
Femur Fracture Other Serious 4/1/2007 65 Female 8/28/2007 Physician Argentina
Primary
Concomitant
Testicular Swelling Life Threatening 1/1/1999 59 Male 9/4/2007 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2006 59 Female 9/6/2007 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious 7/27/2007 83 128 lb 9/6/2007 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 287 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 9/12/2007 Female 287 lb 9/12/2007 Physician United States
Primary
Concomitant
Hyperhidrosis Other Serious 7/1/2007 56 Female 198 lb 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 73 Female 154 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/15/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/2/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 9/18/2006 9/21/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 82 Female 12/6/2007 Physician Australia
Primary
Concomitant
Joint Swelling Other Serious 1/1/2007 46 Male 12/14/2007 Pharmacist Germany
Primary
Concomitant
Interacting
Wrist Fracture Other Serious 11/12/2007 Female 218 lb 12/19/2007 Physician Australia
Primary
Concomitant
Poor Peripheral Circulation Other Serious 8/18/2003 52 Male 213 lb 1/3/2008 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 1/8/2008 Physician United Kingdom
Primary
Concomitant
Myositis Life Threatening 11/14/2007 46 Male 12/28/2007
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 12/28/2007 51 Male 300 lb 1/11/2008 Consumer United Kingdom
Primary
Concomitant
Post Procedural Infection Other Serious 12/24/2007 Male 238 lb 1/30/2008 Pharmacist United Kingdom
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 300 lb 2/4/2008 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 2/6/2008 United Kingdom
Primary
Concomitant
Productive Cough Other Serious 12/10/2007 Female 174 lb 2/8/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 2/8/2008 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 1/25/2008 Belgium
Primary
Concomitant
Wheezing Required Intervention 11/4/2007 57 Female 126 lb 1/25/2008 Pharmacist United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 2/6/2008 Belgium
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 200 lb 2/18/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/23/2008 54 Female 143 lb 2/18/2008 Consumer Mexico
Primary
Concomitant
Radius Fracture Other Serious 11/12/2007 Female 218 lb 2/19/2008 Physician Australia
Primary
Concomitant
Rash Hospitalization 7/17/2006 Male 293 lb 2/26/2008 United Kingdom
Primary
Concomitant
Toothache Hospitalization 10/8/2007 57 Female 2/25/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 1/5/2008 Male 2/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Decreased Appetite 10/1/2007 74 Female 1/10/2008 Consumer United States
Primary
Concomitant
Throat Irritation 10/4/2007 59 Male 201 lb 3/10/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/8/2007 57 Female 3/6/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/8/2007 57 Female 3/25/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Oedema Other Serious 60 Male 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 5/1/2002 Female 4/10/2008 Physician France
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 4/8/2008 Physician Belgium
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 Female 115 lb 4/18/2008 United States
Primary
Concomitant
Hernia Pain Hospitalization 3/27/2008 Female 276 lb 4/21/2008 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 3/17/2008 Male 4/22/2008 Belgium
Primary
Concomitant
Pulmonary Embolism Other Serious 3/12/2007 Male 4/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 71 Male 4/24/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/8/2007 57 Female 4/28/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Radius Fracture Other Serious 11/12/2007 Female 218 lb 4/28/2008 Physician Australia
Primary
Concomitant
Hernia Pain Hospitalization 3/27/2008 Female 276 lb 5/6/2008 Consumer United Kingdom
Primary
Concomitant
Rash Other Serious 4/18/2008 53 Female 159 lb 5/9/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 5/16/2008 Physician United Kingdom
Primary
Concomitant
Hyperhidrosis 12/1/2007 61 Female 154 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Hospitalization 5/22/2008 Physician United States
Primary
Concomitant
Hyperhidrosis 12/1/2007 61 Female 154 lb 5/29/2008 Other Health Professional United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 5/29/2008 Belgium
Primary
Concomitant
Mouth Ulceration Other Serious 68 Male 6/3/2008 Consumer United Kingdom
Primary
Concomitant
Dysarthria Hospitalization 1/21/2008 66 Female 6/12/2008 Physician United States
Primary
Concomitant
Oedema Peripheral 4/28/2008 Female 6/13/2008 United States
Primary
Concomitant
Viral Infection Hospitalization 7/1/2007 Female 180 lb 6/13/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 6/24/2008 Belgium
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 4/21/2008 Female 207 lb 7/7/2008 Consumer United Kingdom
Primary
Concomitant
Wrong Drug Administered Other Serious 61 Female 7/3/2008 United Kingdom
Primary
Secondary
Concomitant
Thrombocythaemia Death 6/29/2008 Female 157 lb 7/18/2008 Other Health Professional United States
Primary
Concomitant
Throat Irritation 10/4/2007 59 Male 201 lb 7/22/2008 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Life Threatening 10/15/2007 72 Male 8/1/2008 Other Health Professional Spain
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 6/19/2008 49 Female 124 lb 8/6/2008 United States
Primary
Concomitant
Thrombocythaemia Death 6/29/2008 Female 157 lb 8/11/2008 Other Health Professional United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 5/2/2008 73 Female 8/8/2008 Physician Spain
Primary
Concomitant
Weight Increased 1/1/2007 52 Male 230 lb 7/7/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/17/2002 44 Female 8/14/2008 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2007 Male 8/18/2008 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2007 63 Female 237 lb 7/7/2008 Consumer United States
Primary
Concomitant
Pruritus 7/20/2008 Female 8/27/2008 United States
Primary
Concomitant
Swelling Face 6/19/2008 Female 8/27/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2007 54 Male 190 lb 8/28/2008 Consumer United States
Primary
Concomitant
Pruritus 6/19/2008 Female 218 lb 8/29/2008 United States
Primary
Concomitant
Blood Glucose Increased Other Serious 8/15/2008 Female 179 lb 8/29/2008 United States
Primary
Concomitant
Nightmare 61 Female 9/5/2008 Consumer United States
Primary
Concomitant
Wound Hospitalization 1/1/2007 Female 9/5/2008 Other Health Professional Sweden
Primary
Concomitant
Herpes Zoster 5/24/2008 Female 175 lb 9/12/2008 Other Health Professional Puerto Rico
Primary
Concomitant
Paraesthesia 7/15/2008 Female 200 lb 9/12/2008 United States
Primary
Concomitant
Accidental Exposure 7/17/2008 Male 196 lb 9/12/2008 Consumer United States
Primary
Concomitant

Drug Data