Metformin Hcl combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Generalised 59 Female 168 lb 1/30/2006 Consumer United States
Primary
Concomitant
Urticaria 3/1/2004 59 Male 181 lb 1/30/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 59 Female 1/24/2006 United States
Primary
Concomitant
Thrombosis Other Serious 59 Female 2/10/2006 United States
Primary
Concomitant
Tremor Other Serious 10/1/2005 51 Male 2/23/2006 Consumer United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 1/1/2005 71 Male 118 lb 2/17/2006 United States
Primary
Concomitant
Epistaxis 2/1/2006 58 Female 315 lb 4/17/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/30/2006 79 Male 167 lb 7/24/2006 United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/13/2002 53 Male 224 lb 8/8/2006 United States
Primary
Concomitant
Vomiting Other Serious 3/1/2006 57 Male 220 lb 7/5/2006 United States
Primary
Concomitant
Injection Site Erythema 5/10/2006 56 Female 176 lb 7/21/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected 2/21/2006 47 Female 208 lb 7/19/2006 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 8/18/2006 54 Female 153 lb 8/30/2006 United States
Primary
Concomitant
Drug Ineffective 2/7/2006 69 Female 181 lb 9/6/2006 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 70 Female 7/19/2006 Consumer United States
Primary
Concomitant
Urticaria Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Contusion 5/1/2006 73 Male 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/25/2006 57 Male 172 lb 9/13/2006 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious 8/18/2006 54 Female 153 lb 9/14/2006 United States
Primary
Concomitant
Rash Generalised 5/16/2006 51 Female 203 lb 7/19/2006 Consumer United States
Primary
Concomitant
Vomiting 4/3/2006 76 Female 190 lb 7/19/2006 Consumer United States
Primary
Concomitant
Cyst Required Intervention 7/1/2005 50 Male 212 lb 9/20/2006 United States
Primary
Concomitant
Stridor Other Serious 1/3/2006 74 Male 194 lb 10/2/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 2/13/2006 57 Female 172 lb 10/2/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 66 Female 162 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 9/10/2006 53 Female 243 lb 9/28/2006 Consumer United States
Primary
Concomitant
Urticaria Other Serious 7/1/2006 Female 10/11/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Required Intervention 6/30/2006 62 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/18/2006 83 Female 121 lb 8/10/2006 Physician United States
Primary
Concomitant
Drug Ineffective Male 8/22/2006 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 10/19/2006 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 9/10/2006 53 Female 243 lb 10/19/2006 Physician United States
Primary
Concomitant
Hypersensitivity Other Serious 8/17/2006 59 Male 170 lb 10/25/2006 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 9/1/2006 Male 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/13/2006 54 Female 220 lb 12/11/2006 Consumer United States
Primary
Concomitant
Breast Swelling 1/1/2006 73 Male 12/28/2006 Consumer United States
Primary
Concomitant
Sinus Congestion 10/11/2006 85 Male 12/28/2006 Consumer United States
Primary
Concomitant
Skin Swelling Hospitalization 7/14/2006 68 Female 108 lb 1/4/2007 Other Health Professional United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 8/14/2006 Female 199 lb 1/10/2007 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 3/20/2006 57 Male 172 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 4/21/2006 75 Female 196 lb 9/26/2006 United States
Primary
Concomitant
Incorrect Dose Administered 61 Male 269 lb 1/9/2007 Physician United States
Primary
Concomitant
Heart Rate Increased 8/1/2006 74 Male 175 lb 10/24/2006 United States
Primary
Concomitant
Viral Infection Other Serious 1/3/2006 74 Male 194 lb 1/16/2007 Pharmacist United States
Primary
Concomitant
Blindness Other Serious 10/1/2006 Male 1/22/2007 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 79 Female 183 lb 1/23/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/28/2006 70 Female 120 lb 1/24/2007 Consumer United States
Primary
Concomitant
Somnolence 7/11/2006 31 Male 280 lb 11/6/2006 United States
Primary
Concomitant
Weight Decreased 7/12/2006 77 Male 160 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting 9/21/2006 59 Female 11/10/2006 Consumer United States
Primary
Concomitant
Blood Pressure Increased 1/1/2006 69 Female 206 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 9/1/2006 76 Female 185 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/19/2007 54 Male 170 lb 1/29/2007 Other Health Professional United States
Primary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 44 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Amnesia Other Serious 52 Male 200 lb 6/2/2006 Physician United States
Primary
Concomitant
Weight Increased 5/1/2006 63 Female 174 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 75 Female 170 lb 2/8/2007 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/1/2003 Female 2/23/2007 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 2/3/2007 52 Female 2/15/2007 Consumer United States
Primary
Concomitant
Ulcer Hospitalization 1/19/2007 54 Male 170 lb 2/12/2007 United States
Primary
Concomitant
Splenic Infarction Other Serious 10/12/2006 49 Female 148 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased 8/11/2006 54 Female 230 lb 10/16/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance 1/1/2006 54 Male 10/16/2006 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/8/2007 Physician United States
Primary
Concomitant
Hypertension Hospitalization 64 Female 3/21/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/18/2007 79 Male 141 lb 3/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 8/19/2005 62 Female 211 lb 2/23/2006 Other Health Professional United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Skin Irritation Other Serious 11/27/2004 84 Male 5/3/2005 United States
Primary
Concomitant
Pain In Extremity 8/1/2006 74 Male 175 lb 1/23/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/27/2006 Female 220 lb 4/9/2007 Physician United States
Primary
Concomitant
Throat Tightness 10/1/2006 67 Female 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 1/1/2006 63 Male 309 lb 1/12/2007 Other Health Professional United States
Primary
Concomitant
Tremor 10/26/2006 62 Male 200 lb 1/12/2007 Consumer United States
Primary
Concomitant
Diplopia 10/24/2006 74 Male 310 lb 1/12/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 2/3/2007 52 Female 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 11/1/2006 50 Female 165 lb 4/11/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/18/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 80 Male 142 lb 4/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 2/1/2006 68 Male 249 lb 1/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 6/1/2006 57 Female 185 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Projectile 7/1/2006 67 Female 4/17/2007 Physician United States
Primary
Concomitant
Injection Site Pain 12/18/2006 67 Female 270 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/18/2007 73 Male 163 lb 4/23/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/2/2007 72 Male 216 lb 3/11/2007 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Other Serious 4/1/2007 Male 170 lb 4/27/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 4/9/2007 65 Male 184 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 1/1/2006 70 Female 254 lb 1/30/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 4/10/2007 Male 184 lb 5/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/9/2007 Male 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/14/2007 79 Male 130 lb 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/17/2006 71 Male 154 lb 5/3/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 79 Male 142 lb 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence 12/31/2006 Male 2/16/2007 United States
Primary
Concomitant
Tongue Discolouration 11/1/2006 60 Female 2/16/2007 United States
Primary
Concomitant
Haemorrhage Other Serious 1/1/1993 43 Male 5/9/2007 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/1/2007 78 Male 4/30/2007 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 2/15/2007 56 Female 5/9/2007 Consumer United States
Primary
Concomitant
Chromaturia 1/7/2007 58 Male 2/16/2007 United States
Primary
Concomitant
Occult Blood Positive Hospitalization 4/9/2007 76 Male 238 lb 5/15/2007 Pharmacist United States
Primary
Concomitant
Rhinorrhoea 12/16/2006 65 Female 2/16/2007 United States
Primary
Secondary
Concomitant
Angioedema 12/4/2006 65 Female 2/16/2007 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/16/2007 81 Male 181 lb 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/1/2006 33 Female 5/29/2007 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 6/27/2006 45 Male 3/28/2007 Other Health Professional United States
Primary
Concomitant
Pain 1/1/2006 78 Female 3/13/2007 Consumer United States
Primary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 6/1/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia 2/1/2007 81 Male 200 lb 4/12/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 61 Female 6/11/2007 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious 2/1/2004 77 Female 6/11/2007 Consumer United States
Primary
Concomitant
Syncope 1/1/2007 65 Male 5/17/2007 Pharmacist United States
Primary
Concomitant
Rash Generalised 11/15/2006 74 Female 158 lb 5/17/2007 Physician United States
Primary
Concomitant
Sensation Of Pressure Other Serious 11/1/2006 57 Male 6/12/2007 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 92 Male 6/12/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2007 Male 142 lb 6/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting 3/6/2007 77 Female 165 lb 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 79 Male 130 lb 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2007 79 Male 142 lb 6/8/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 11/4/2006 63 Male 435 lb 4/10/2007 Consumer United States
Primary
Concomitant
Tremor 1/1/2007 68 Female 4/10/2007 Consumer United States
Primary
Concomitant
Unevaluable Event Disability Male 6/18/2007 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/14/2007 Male 142 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity 10/1/2006 67 Female 4/10/2007 Physician United States
Primary
Concomitant
Fatigue 12/1/2006 69 Female 230 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 62 Female 185 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/3/2007 60 Male 6/21/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2004 69 Female 6/21/2007 Consumer United States
Primary
Concomitant
Tremor 81 Female 170 lb 6/22/2007 Consumer United States
Primary
Concomitant
Muscular Weakness 78 Female 155 lb 6/25/2007 United States
Primary
Concomitant
Dyspnoea 1/13/2007 54 Male 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 1/1/2006 66 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/15/2006 69 Female 250 lb 4/26/2007 United States
Primary
Concomitant
Muscle Spasms Other Serious 12/13/2006 70 Female 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/7/2007 Female 6/29/2007 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 56 Female 279 lb 4/10/2007 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/1/2003 Female 7/6/2007 Lawyer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 6/1/2007 Female 220 lb 7/9/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 6/29/2007 Male 180 lb 7/10/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/22/2007 60 Male 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 7/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data