Metformin Hcl combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombosis Other Serious 59 Female 1/24/2006 United States
Primary
Concomitant
Thrombosis Other Serious 59 Female 2/10/2006 United States
Primary
Concomitant
Therapeutic Response Unexpected 5/23/2006 51 Female 243 lb 7/19/2006 Physician United States
Primary
Concomitant
Victim Of Crime Other Serious 1/1/2005 37 Female 295 lb 9/7/2006 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 42 Male 420 lb 10/30/2006 Physician United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 10/2/2006 46 Female 12/14/2006 United States
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2007 Female 248 lb 1/24/2007 Physician United States
Primary
Concomitant
Thrombosis Other Serious 6/1/2003 Female 2/23/2007 Lawyer United States
Primary
Concomitant
Panic Reaction Other Serious 2/1/2007 Female 200 lb 2/27/2007 Consumer United States
Primary
Concomitant
Restless Legs Syndrome 7/28/2006 45 Female 300 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor 8/7/2006 25 Female 133 lb 10/16/2006 Consumer United States
Primary
Concomitant
Migraine Other Serious 1/1/2007 Female 248 lb 3/5/2007 Physician United States
Primary
Concomitant
Restless Legs Syndrome 7/28/2006 45 Female 301 lb 3/7/2007 Consumer United States
Primary
Secondary
Concomitant
Social Phobia Other Serious 1/1/2004 15 Female 137 lb 3/23/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Disability 1/1/2003 46 Female 8/17/2006 Lawyer United States
Primary
Secondary
Concomitant
Palpitations 37 Female 224 lb 1/23/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 Male 220 lb 1/8/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 4/6/2007 57 Male 400 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 10/4/2006 72 Female 180 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/1/1993 43 Male 5/9/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 Female 214 lb 5/17/2007 Consumer United States
Primary
Concomitant
Panic Disorder Other Serious 28 Female 150 lb 5/16/2007 United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious Female 3/28/2007 United States
Primary
Secondary
Concomitant
Insomnia 3/1/2007 45 Male 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 12/1/2006 55 Female 186 lb 4/10/2007 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/1/2003 Female 7/6/2007 Lawyer United States
Primary
Concomitant
Drug Ineffective 3/1/2006 47 Female 218 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Schizoaffective Disorder Hospitalization 63 Male 8/8/2007 Consumer United States
Primary
Concomitant
Drug Effect Decreased Death 6/1/2007 42 Male 279 lb 9/11/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 9/25/2007 United States
Primary
Concomitant
Headache 4/26/2007 50 Female 8/16/2007 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/8/2007 United States
Primary
Concomitant
Drug Ineffective 9/17/2007 50 Male 11/12/2007 Consumer United States
Primary
Concomitant
Knee Operation Hospitalization 3/28/2007 38 Female 264 lb 11/15/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/21/2007 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Joint Swelling 6/15/2007 59 Female 11/16/2007 United States
Primary
Concomitant
Headache 8/7/2007 49 Female 11/16/2007 United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 150 lb 12/5/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 5/1/2007 Female 137 lb 12/17/2007 Physician France
Primary
Secondary
Concomitant
Drug Ineffective 9/17/2007 50 Male 12/27/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 148 lb 1/28/2008 Consumer United States
Primary
Concomitant
Haematospermia Other Serious 1/1/2008 Male 227 lb 2/15/2008 Consumer United States
Primary
Concomitant
Weight Decreased 10/26/2007 53 Male 206 lb 1/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 1/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 Female 166 lb 1/10/2008 Consumer United States
Primary
Concomitant
Dissociative Fugue Other Serious 2/23/2008 Male 162 lb 3/6/2008 United States
Primary
Secondary
Concomitant
Paralysis Other Serious 1/1/2008 Female 160 lb 4/1/2008 United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/4/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/4/2008 United States
Primary
Secondary
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/8/2008 69 Male 181 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/10/2008 United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/18/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 31 Female 4/11/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 4/21/2008 Consumer United States
Primary
Secondary
Post-traumatic Stress Disorder Other Serious 1/1/2008 Female 160 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 4/28/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 180 lb 5/2/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/2/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/6/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 210 lb 5/7/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/15/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 160 lb 5/23/2008 United States
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2008 31 Female 5/20/2008 Physician United States
Primary
Concomitant
Sternal Fracture Hospitalization 12/1/2007 Female 160 lb 5/30/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/28/2007 Female 280 lb 6/6/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 4/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2007 67 Female 220 lb 4/10/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 10/4/2005 Female 210 lb 6/23/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2008 Male 7/7/2008 Consumer United States
Primary
Concomitant
Stress Hospitalization 5/1/2008 Female 7/22/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2004 Female 205 lb 7/31/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 60 Female 147 lb 7/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2007 67 Female 220 lb 7/7/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased 1/1/2005 59 Female 150 lb 7/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 76 Female 165 lb 8/26/2008 Consumer United States
Primary
Concomitant
Pain Hospitalization 11/1/2007 60 Female 125 lb 8/27/2008 Consumer United States
Primary
Concomitant
Weight Increased 65 Female 8/15/2008 United States
Primary
Concomitant
Wheezing Other Serious 8/23/2008 Female 9/5/2008 Consumer Canada
Primary
Concomitant
Weight Increased 47 Female 220 lb 9/23/2008 Consumer United States
Primary
Concomitant
Overdose Other Serious 1/1/2002 56 Female 9/18/2008 Physician United States
Primary
Concomitant
Homicidal Ideation Other Serious 9/26/2007 59 Female 9/29/2008 Other Health Professional Australia
Primary
Concomitant
Overdose Other Serious 1/1/2002 56 Female 10/14/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 43 Male 270 lb 10/17/2008 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 11/1/2008 64 Male 12/11/2008 Physician United States
Primary
Concomitant
Increased Appetite 10/1/2008 43 Male 285 lb 12/2/2008 Consumer United States
Primary
Concomitant
Blepharospasm Disability 12/1/2007 53 Female 1/13/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Death 1/1/1990 51 Male 204 lb 1/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 7/2/2008 63 Female 1/26/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/30/2008 69 Male 203 lb 3/4/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 12/31/2008 Female 204 lb 3/14/2009 Physician United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 2/1/2009 Female 3/20/2009 Physician United States
Primary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Vomiting 11/8/2000 50 Female 163 lb 4/2/2009 United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 42 Female 257 lb 4/3/2009 United States
Primary
Concomitant
Dizziness Hospitalization 3/24/2009 Female 4/3/2009 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/17/2008 Female 111 lb 4/8/2009 Consumer United States
Primary
Concomitant
Vaginal Odour Hospitalization 1/1/2004 44 Female 170 lb 4/14/2009 United States
Primary
Concomitant
Schizoaffective Disorder Hospitalization 3/1/2007 42 Female 4/21/2009 United States
Primary
Concomitant
Throat Tightness 3/21/2008 32 Female 295 lb 4/24/2009 United States
Primary
Concomitant
Weight Increased Other Serious 3/28/2003 44 Female 240 lb 5/18/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 34 Female 225 lb 5/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/24/2000 40 Female 185 lb 5/21/2009 United States
Primary
Concomitant
Palpitations Hospitalization 4/1/2009 Female 148 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Flushing Female 5/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 45 Male 185 lb 6/9/2009 United States
Primary
Concomitant
Multiple Sclerosis Relapse 5/1/2008 35 Female 207 lb 5/11/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 51 Male 256 lb 7/7/2009 United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2001 16 Female 200 lb 7/9/2009 United States
Primary
Concomitant
Abortion Spontaneous Other Serious 4/19/2009 Female 206 lb 7/9/2009 Other Health Professional United States
Primary
Secondary
Tardive Dyskinesia Other Serious 1/1/2006 28 Female 218 lb 7/13/2009 United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 5/29/2009 43 Female 238 lb 7/1/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/5/2003 38 Female 235 lb 7/14/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 42 Male 213 lb 7/15/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Weight Increased Other Serious 11/19/1999 44 Female 256 lb 7/17/2009 United States
Primary
Concomitant
Abortion Spontaneous Other Serious 4/19/2009 Female 206 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/8/2008 Female 8/18/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2004 40 Female 292 lb 8/21/2009 United States
Primary
Concomitant
Abortion Spontaneous Other Serious 4/19/2009 Female 197 lb 8/21/2009 Other Health Professional United States
Primary
Secondary
Pruritus 1/26/2009 Female 119 lb 8/22/2009 Consumer United States
Primary
Concomitant
Nausea 3/1/2009 Female 8/22/2009 United States
Primary
Concomitant
Pain Hospitalization 11/1/2007 60 Female 125 lb 8/28/2009 Pharmacist United States
Primary
Secondary
Concomitant
Hyperhidrosis 6/1/2009 Female 198 lb 8/29/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2007 60 Female 125 lb 9/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 61 Female 9/9/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2007 60 Female 125 lb 9/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 5/25/2009 Female 175 lb 9/18/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus 9/1/2005 43 Female 285 lb 9/23/2009 United States
Primary
Concomitant
Obesity 1/1/2001 35 Female 195 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased 1/1/2005 25 Female 312 lb 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 1/1/2004 41 Female 271 lb 9/23/2009 United States
Primary
Concomitant
Vaginitis Bacterial 1/1/1999 39 Female 150 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 33 Female 170 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/3/2006 27 Female 220 lb 9/23/2009 United States
Primary
Concomitant
Viral Infection 1/1/2003 36 Female 247 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Viral Infection 6/15/1999 6 Male 95 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/3/2004 13 Female 254 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/23/2009 United States
Primary
Concomitant
Metabolic Syndrome 5/17/2006 46 Male 260 lb 9/23/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection 1/23/2004 40 Female 150 lb 9/23/2009 United States
Primary
Concomitant
Vomiting 11/8/2000 50 Female 163 lb 9/23/2009 United States
Primary
Concomitant
Insomnia 4/9/2009 59 Male 9/24/2009 Physician United States
Primary
Concomitant

Drug Data