Metformin Hcl combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Other Serious 1/1/2005 75 Female 1/16/2006 Canada
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 10/18/2005 Male 160 lb 12/14/2005 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 60 Female 2/20/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/18/2005 78 Female 162 lb 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 10/14/2005 54 Female 204 lb 1/20/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 10/16/2005 64 Female 170 lb 1/20/2006 United States
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 6/16/2006 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/4/2005 68 Female 6/19/2006 Physician United States
Primary
Concomitant
Weight Decreased 3/23/2006 59 Male 264 lb 4/17/2006 Consumer United States
Primary
Concomitant
Skin Haemorrhage Required Intervention 8/23/2006 Female 250 lb 8/24/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 3/24/2006 59 Female 177 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 4/1/2006 40 Female 228 lb 7/19/2006 Consumer United States
Primary
Concomitant
Injection Site Urticaria 1/1/2006 51 Female 7/19/2006 United States
Primary
Concomitant
Weight Decreased 3/5/2006 55 Female 170 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 53 Female 185 lb 7/19/2006 Consumer United States
Primary
Concomitant
Tremor 3/11/2006 53 Female 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis 5/31/2006 62 Male 284 lb 7/19/2006 Consumer United States
Primary
Concomitant
Lipoma Of Breast Other Serious 4/1/2006 55 Female 128 lb 9/11/2006 United States
Primary
Concomitant
Vomiting Projectile Hospitalization 7/26/2006 62 Female 180 lb 9/11/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Disability 6/14/2006 51 Male 223 lb 9/18/2006 Physician United States
Primary
Concomitant
Weight Decreased 4/19/2006 63 Female 241 lb 7/19/2006 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 8/3/2006 53 Female 10/3/2006 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 4/12/2005 57 Male 271 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint 38 Female 210 lb 10/4/2006 Consumer United States
Primary
Concomitant
Blood Calcium Decreased Hospitalization 7/1/2006 58 Female 189 lb 10/13/2006 Consumer United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 8/31/2005 74 Male 8/21/2006 Pharmacist United States
Primary
Concomitant
Gait Disturbance Other Serious Female 155 lb 10/20/2006 United States
Primary
Concomitant
Temperature Intolerance Disability 1/1/2006 51 Male 223 lb 10/31/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/26/2006 62 Female 180 lb 11/14/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 70 Male 191 lb 11/15/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Dermatitis Herpetiformis 47 Female 11/30/2006 Consumer United States
Primary
Concomitant
Overgrowth Bacterial 1/1/2006 76 Female 157 lb 11/30/2006 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 7/1/2006 38 Female 210 lb 12/6/2006 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 10/1/2006 60 Female 252 lb 12/14/2006 Consumer United States
Primary
Concomitant
Nasal Dryness 63 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 72 Female 12/28/2006 Consumer United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/1/2006 60 Female 252 lb 12/21/2006 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/17/2006 72 Female 1/4/2007 Other Health Professional Canada
Primary
Concomitant
Drug Ineffective 71 Female 9/12/2006 United States
Primary
Concomitant
Wheezing Other Serious 72 Female 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Middle Insomnia 1/1/2006 40 Female 120 lb 10/11/2006 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence 1/1/2000 53 Female 148 lb 10/19/2006 United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 67 Male 255 lb 1/18/2007 Physician United States
Primary
Concomitant
Injection Site Nodule 7/24/2006 45 Female 201 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2006 59 Female 118 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 7/15/2005 58 Female 300 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Weight Decreased 6/25/2006 60 Female 280 lb 10/16/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/12/2007 Male 250 lb 1/30/2007 Pharmacist Canada
Primary
Concomitant
Somnolence 11/8/2005 54 Female 170 lb 11/10/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 73 Male 11/10/2006 Physician United States
Primary
Concomitant
Somnolence 11/8/2005 54 Female 170 lb 11/10/2006 Consumer United States
Primary
Concomitant
Paradoxical Drug Reaction Hospitalization 1/24/2007 78 Female 112 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2007 63 Female 2/1/2007 Pharmacist Canada
Primary
Concomitant
Weight Decreased 7/1/2006 66 Female 189 lb 10/16/2006 Consumer United States
Primary
Concomitant
Ovarian Cyst Hospitalization 1/1/2006 42 Female 220 lb 1/31/2007 Consumer United States
Primary
Concomitant
Blood Glucose Abnormal Other Serious 5/31/2006 73 160 lb 8/17/2006 United States
Primary
Concomitant
Blood Cholesterol Increased Other Serious 67 Female 211 lb 11/17/2005 United States
Primary
Concomitant
Syncope Hospitalization 11/22/2006 76 Male 2/16/2007 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 10/20/2006 52 Female 2/28/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 11/5/2006 Female 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Goitre Other Serious 1/1/2005 56 Male 3/1/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 12/1/2006 Female 3/6/2007 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 225 lb 2/27/2007 United States
Primary
Concomitant
Treatment Noncompliance 4/27/2006 65 Male 261 lb 3/7/2007 Consumer United States
Primary
Secondary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 3/15/2007 Physician United States
Primary
Concomitant
Pain Other Serious 1/20/2007 Female 297 lb 3/21/2007 Consumer Canada
Primary
Concomitant
Myalgia Hospitalization 8/19/2005 62 Female 211 lb 2/23/2006 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal 12/7/2006 65 Female 143 lb 3/27/2007 Consumer United States
Primary
Concomitant
Sleep Walking Other Serious 10/23/2006 Male 3/30/2007 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/1/2007 Male 181 lb 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Ovarian Cyst Hospitalization 10/1/2006 42 Female 220 lb 3/29/2007 Physician United States
Primary
Concomitant
Throat Tightness 10/1/2006 67 Female 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 10/31/2006 74 Female 164 lb 1/12/2007 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 3/1/2007 Female 4/16/2007 Physician United States
Primary
Concomitant
Weight Decreased 11/22/2006 67 Female 225 lb 1/12/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 12/1/2006 Female 4/17/2007 Consumer Canada
Primary
Concomitant
Weight Decreased 2/1/2006 74 Female 240 lb 1/12/2007 Consumer United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication 8/1/2006 49 Male 304 lb 1/12/2007 Consumer United States
Primary
Concomitant
Stress 11/1/2006 44 Female 196 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased 61 Female 222 lb 1/12/2007 Consumer United States
Primary
Concomitant
Injection Site Discomfort 10/2/2006 60 Male 232 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased 58 Female 184 lb 1/12/2007 Physician United States
Primary
Concomitant
Injection Site Urticaria 11/4/2006 42 Female 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 11/1/2006 76 Female 180 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea 8/1/2006 54 Female 178 lb 1/12/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 55 Female 240 lb 4/18/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased 12/1/2006 79 Male 1/12/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 62 Female 164 lb 4/23/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/1/2007 Male 181 lb 4/27/2007 United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/18/2007 Female 291 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
Throat Irritation Male 203 lb 4/30/2007 United States
Primary
Concomitant
Blood Glucose Increased 58 Female 150 lb 4/30/2007 Consumer United States
Primary
Concomitant
Reflux Oesophagitis 77 Female 183 lb 4/30/2007 United States
Primary
Concomitant
Drug Ineffective 66 Female 176 lb 4/30/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Ureteric Perforation Other Serious 1/1/2006 58 Female 162 lb 5/4/2007 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 1/1/2006 57 Female 148 lb 5/10/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 11/2/2006 52 Female 200 lb 2/16/2007 Physician United States
Primary
Concomitant
Rhinorrhoea 11/9/2006 61 Female 2/16/2007 United States
Primary
Concomitant
Blood Glucose Increased 11/5/2006 71 Female 2/16/2007 Physician United States
Primary
Concomitant
Frequent Bowel Movements 11/11/2006 72 Female 2/16/2007 United States
Primary
Concomitant
Drug Ineffective 1/9/2007 60 Female 2/16/2007 United States
Primary
Concomitant
Tremor Other Serious 5/8/2007 33 Female 134 lb 5/15/2007 Consumer Brazil
Primary
Concomitant
Renal Failure Other Serious 9/21/2006 69 Female 5/15/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 12/1/2006 Female 227 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Goitre Other Serious 1/1/2005 56 Male 5/21/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 12/1/2006 Female 227 lb 5/23/2007 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 6/1/2005 68 Male 253 lb 5/25/2007 Physician United States
Primary
Concomitant
Weight Increased 1/1/2006 54 Female 147 lb 3/13/2007 Consumer United States
Primary
Concomitant
Somnolence 11/8/2005 54 Female 170 lb 3/13/2007 Consumer United States
Primary
Concomitant
Somnolence 11/8/2005 54 Female 170 lb 3/13/2007 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 10/17/2006 Female 192 lb 6/1/2007 Physician United States
Primary
Concomitant
Insomnia 1/1/2005 36 Female 250 lb 4/12/2007 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation 3/21/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Rash Generalised 11/15/2006 74 Female 158 lb 5/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 62 Female 164 lb 6/5/2007 Consumer United States
Primary
Concomitant
Weight Decreased 11/4/2006 63 Male 435 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 55 Female 240 lb 4/10/2007 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort 2/11/2007 58 Female 4/10/2007 Consumer United States
Primary
Concomitant
Weight Increased 3/1/2006 60 Female 118 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 3/1/2006 60 Female 205 lb 4/10/2007 Consumer United States
Primary
Concomitant
Hypersensitivity 10/1/2006 67 Female 4/10/2007 Physician United States
Primary
Concomitant
Weight Decreased 11/1/2006 81 Female 180 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased 4/3/2006 76 Female 163 lb 4/10/2007 Consumer United States
Primary
Concomitant
Urticaria 12/1/2006 63 Female 180 lb 4/10/2007 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 5/18/2007 Female 214 lb 6/22/2007 Physician United States
Primary
Concomitant
Unevaluable Event Other Serious 4/1/2007 63 Female 6/26/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 7/12/2006 74 Female 201 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Hot Flush Other Serious 63 Female 234 lb 6/29/2007 United States
Primary
Concomitant
Paraesthesia 12/1/2006 45 Male 4/10/2007 Pharmacist United States
Primary
Concomitant
Faeces Discoloured 5/1/2007 73 Female 6/11/2007 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 4/1/2007 64 Female 328 lb 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/1/2006 55 Female 170 lb 7/6/2007 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion Hospitalization 55 Female 7/12/2007 Canada
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 5/18/2007 Female 203 lb 7/19/2007 Physician United States
Primary
Concomitant
Oedema Peripheral 7/23/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 70 Female 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 11/17/2006 63 Female 272 lb 7/23/2007 Consumer United States
Primary
Concomitant
Paronychia Female 7/23/2007 Other Health Professional United States
Primary
Concomitant
Renal Cyst Other Serious 65 Female 153 lb 7/24/2007 Physician United States
Primary
Concomitant
Somnambulism Other Serious 8/1/2006 Male 330 lb 7/25/2007 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/6/2006 68 Female 7/26/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 4/18/2007 59 Female 209 lb 7/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Loss Poor Hospitalization 1/1/2002 52 Female 8/7/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/31/2007 87 Female 249 lb 8/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 1/23/2007 Male 8/9/2007 Physician United States
Primary
Concomitant

Drug Data