Metformin Hcl combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Headache 1/1/2005 35 Female 119 lb 1/30/2006 Consumer United States
Primary
Concomitant
Rash Other Serious 1/1/2005 25 Female 2/22/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2005 Female 2/24/2006 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2005 63 Male 3/16/2006 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Lethargy Other Serious 5/16/2006 76 Female 8/18/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 1/29/2006 64 Male 249 lb 7/19/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/1/2006 70 Female 10/3/2006 Physician France
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/17/2006 47 Female 10/10/2006 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/1/2006 67 Female 181 lb 10/2/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/15/2005 79 Female 10/27/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Prostate Cancer Life Threatening 1/1/1996 72 Male 150 lb 10/27/2006 Physician Ireland
Primary
Concomitant
Renal Failure Acute Hospitalization 8/5/2006 58 Male 10/20/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Malaise Hospitalization 5/28/2005 94 Female 11/13/2006 Physician France
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Oedema Peripheral 8/1/2005 68 Male 11/30/2006 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Visual Acuity Reduced Disability 9/1/2006 Female 1/5/2007 Consumer United States
Primary
Concomitant
Insomnia 5/1/2006 73 Female 160 lb 10/11/2006 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Post Procedural Complication Hospitalization 1/1/2006 62 Female 200 lb 1/9/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/20/2006 58 Female 212 lb 10/19/2006 Physician United States
Primary
Concomitant
Dry Throat 1/1/2006 47 Female 130 lb 10/24/2006 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 12/25/2005 Male 307 lb 12/6/2006 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 12/25/2005 Male 307 lb 12/1/2006 Consumer United States
Primary
Concomitant
Localised Infection Other Serious 4/1/2006 57 Male 255 lb 1/30/2007 United States
Primary
Concomitant
Rhabdomyolysis Death 4/1/2006 69 Female 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 2/26/2007 Consumer France
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
Therapeutic Response Unexpected 3/6/2006 35 Female 2/28/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Palpitations 37 Female 224 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/1/2006 78 Male 4/17/2007 Consumer United Kingdom
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 3/29/2007 Female 232 lb 4/24/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/21/2007 84 Female 148 lb 4/30/2007
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 2/23/2007 68 Female 251 lb 5/2/2007 Physician United Kingdom
Primary
Concomitant
Thought Insertion Disability 10/1/2006 53 Female 5/11/2007 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 11/5/2006 71 Female 2/16/2007 Physician United States
Primary
Concomitant
Panic Disorder Other Serious 28 Female 150 lb 5/16/2007 United States
Primary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 2/28/2006 80 Male 12/13/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 11/1/2006 78 Male 218 lb 5/24/2007 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/16/2006 66 Male 187 lb 2/9/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 3/1/2007 78 Male 218 lb 6/11/2007 Consumer United Kingdom
Primary
Concomitant
Therapeutic Response Unexpected Hospitalization 12/10/2006 53 Female 6/14/2007 Consumer United States
Primary
Concomitant
Paraesthesia 12/29/2006 56 Female 250 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/8/2007 71 Male 142 lb 6/28/2007 Physician United Kingdom
Primary
Concomitant
Thought Insertion Disability 10/1/2006 53 Female 6/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Restlessness Other Serious 7/1/2007 50 Male 7/17/2007 Consumer Canada
Primary
Concomitant
Pancreatic Carcinoma Death 9/1/2004 Male 126 lb 7/24/2007 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/9/2003 59 Male 7/26/2007 Consumer United States
Primary
Concomitant
Medication Error 6/13/2007 57 Male 8/8/2007 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/25/2006 71 Female 8/3/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 240 lb 8/10/2007 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2006 67 Female 8/7/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/31/2004 50 Female 171 lb 7/9/2007 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 50 Female 8/17/2007 Physician France
Primary
Concomitant
Vomiting 8/1/2006 49 Female 7/11/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 8/1/2007 Female 206 lb 8/28/2007 Consumer United States
Primary
Concomitant
Testicular Swelling Life Threatening 1/1/1999 59 Male 9/4/2007 Consumer United States
Primary
Concomitant
Sinusitis 3/1/2007 60 Female 7/11/2007 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 8/16/2007 74 Male 198 lb 9/5/2007 Physician
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 67 Male 217 lb 9/11/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 11/17/2000 35 Female 216 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2006 70 Female 214 lb 9/28/2007 Physician Australia
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2007 35 Female 10/12/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 75 Female 195 lb 9/17/2007 Consumer United States
Primary
Concomitant
Myalgia Other Serious 1/1/2003 70 Female 287 lb 10/19/2007 Physician Australia
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/15/2007 83 Female 10/30/2007 Italy
Primary
Secondary
Concomitant
Dizziness 9/7/2006 76 Male 11/13/2007 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2006 65 Male 11/13/2007 Consumer United States
Primary
Concomitant
Cough 11/1/2006 78 Female 11/13/2007 Consumer United States
Primary
Concomitant
Weight Increased 9/1/2006 39 Male 11/14/2007 Consumer United States
Primary
Secondary
Concomitant
Rash 68 Female 11/14/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2004 41 Female 147 lb 11/19/2007 Physician United States
Primary
Concomitant
Cholecystectomy Hospitalization Female 11/30/2007 Belgium
Primary
Concomitant
Blood Creatinine Increased 6/19/2007 57 Male 250 lb 11/16/2007 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 2/19/2007 55 Male 236 lb 12/4/2007 Physician Canada
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 11/6/2007 50 Male 12/7/2007 Physician Canada
Primary
Concomitant
Vomiting Required Intervention 10/15/2006 58 Female 195 lb 10/8/2007 Consumer United States
Primary
Concomitant
Neuropathic Arthropathy Other Serious 8/1/2007 Male 12/18/2007 Consumer United States
Primary
Secondary
Concomitant
Medication Residue Male 12/20/2007 Consumer United States
Primary
Concomitant
Skin Haemorrhage Other Serious 12/1/2006 72 Male 12/13/2007 Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 249 lb 12/21/2007 Consumer United States
Primary
Concomitant
Tremor 9/20/2007 61 Female 10/9/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/21/2007 76 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 9/17/2007 Male 1/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Formication Hospitalization 2/26/2007 51 Male 1/17/2008
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 1/5/2008 Male 203 lb 1/18/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 Male 188 lb 1/24/2008 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2007 35 Female 1/29/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization Male 1/21/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 5/4/2006 69 Male 1/24/2008 Netherlands
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 Male 188 lb 2/6/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 345 lb 1/30/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 1/25/2008 Belgium
Primary
Concomitant
Vomiting Other Serious 1/14/2008 68 Male 2/12/2008 Other Health Professional Germany
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 2/6/2008 Belgium
Primary
Concomitant
Breast Mass Other Serious 12/1/2007 58 Female 212 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 68 Male 2/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint 28 Female 2/22/2008 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2007 57 Male 2/27/2008 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/5/2006 69 Male 2/28/2008 Netherlands
Primary
Concomitant
Paraesthesia 9/27/2007 53 Female 145 lb 1/10/2008 Consumer United States
Primary
Concomitant
Alopecia 8/1/2007 70 Female 167 lb 1/10/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 7/14/2007 71 Male 269 lb 7/27/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 3/17/2008 United Kingdom
Primary
Concomitant
Oedema Peripheral 8/1/2007 33 Female 260 lb 8/27/2007 Consumer United States
Primary
Concomitant
Oedema Other Serious 60 Male 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 68 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 65 Male 163 lb 4/4/2008 Consumer Germany
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 4/8/2008 Physician Belgium
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 195 lb 4/16/2008 Physician United States
Primary
Concomitant
Renal Impairment 82 Male 4/22/2008 Germany
Primary
Concomitant
Drug Ineffective 2/1/2008 80 Male 218 lb 4/30/2008 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 5/3/2007 59 Male 4/30/2008 United States
Primary
Concomitant
Thrombocytopenia 5/3/2007 59 Male 5/6/2008 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 12/1/2007 Female 212 lb 5/12/2008 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 195 lb 5/8/2008 Physician United States
Primary
Concomitant
Infection Hospitalization 2/19/2007 Male 236 lb 5/14/2008 Physician Canada
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/9/2008 58 Female 5/14/2008 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 3/12/2008 66 Female 146 lb 5/19/2008 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2008 Female 199 lb 5/21/2008 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 2/19/2007 Male 236 lb 5/23/2008 Physician Canada
Primary
Secondary
Concomitant
Death Death 5/6/2008 Female 149 lb 5/22/2008 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 1/1/2008 Female 199 lb 6/2/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 5/29/2008 Belgium
Primary
Concomitant
Hyperlipidaemia Hospitalization 4/2/2008 Female 230 lb 6/4/2008 Consumer United States
Primary
Concomitant
Renal Impairment 7/20/2007 82 Male 5/30/2008 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 9/25/2007 Male 269 lb 4/7/2008 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2005 61 Male 190 lb 4/10/2008 Consumer United States
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/11/2008 United Kingdom
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Irritability 10/1/2007 43 Female 187 lb 6/25/2008 Consumer United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 6/24/2008 Belgium
Primary
Concomitant
Sinusitis 3/12/2007 64 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Muscle Spasms 3/1/2007 55 Female 4/10/2008 Consumer United States
Primary
Concomitant

Drug Data