Metformin Hcl combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Hospitalization 6/21/2005 58 Female 1/26/2006 Physician Australia
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Death 11/10/2005 56 Female 2/17/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/20/2006 70 Male 335 lb 9/7/2006 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 8/17/2006 59 Male 175 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Vomiting Projectile Hospitalization 7/26/2006 62 Female 180 lb 9/11/2006 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/12/2006 Male 154 lb 9/21/2006 Physician France
Primary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 9/27/2006 Pharmacist Canada
Primary
Concomitant
Obstructive Airways Disorder Hospitalization 8/17/2006 49 Male 9/28/2006 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 9/14/2006 65 Male 10/11/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Pneumonia Death 6/1/2006 72 Male 265 lb 10/20/2006 Physician Germany
Primary
Concomitant
Pneumonia 2/20/2006 60 Female 8/22/2006 United States
Primary
Concomitant
Dysgeusia 4/1/2006 75 Male 8/22/2006 United States
Primary
Concomitant
Drug Ineffective Male 8/22/2006 United States
Primary
Concomitant
Bone Pain 3/1/2006 72 Female 271 lb 8/22/2006 United States
Primary
Concomitant
Dyspnoea 1/7/2006 60 Female 8/22/2006 United States
Primary
Concomitant
Urine Flow Decreased 3/15/2006 76 Male 211 lb 8/22/2006 United States
Primary
Concomitant
Hypersensitivity Other Serious 8/17/2006 59 Male 170 lb 10/25/2006 Physician United States
Primary
Concomitant
Pneumonia Death 6/1/2006 72 Male 265 lb 11/3/2006 Physician Germany
Primary
Concomitant
Pancytopenia Other Serious 11/11/2005 77 Male 160 lb 8/29/2006 Physician United States
Primary
Concomitant
Respiratory Failure Death 10/16/2006 86 Male 11/15/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/26/2006 62 Female 180 lb 11/14/2006 Other Health Professional United States
Primary
Concomitant
Breast Cancer Female Other Serious 10/1/2005 57 Female 11/17/2006 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 10/1/2005 57 Female 12/1/2006 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 7/12/2006 Male 154 lb 12/28/2006 Physician France
Primary
Concomitant
Visual Acuity Reduced Disability 9/1/2006 Female 1/5/2007 Consumer United States
Primary
Concomitant
Swollen Tongue Life Threatening 1/6/2007 58 Female 1/11/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/17/2006 68 Male 1/15/2007 Pharmacist Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 12/25/2005 Male 307 lb 12/6/2006 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 12/25/2005 Male 307 lb 12/1/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Other Serious 10/1/2005 57 Female 1/22/2007 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 5/9/2006 53 Male 260 lb 2/2/2007 Physician Canada
Primary
Concomitant
Hypoglycaemia Life Threatening 5/9/2006 53 Male 260 lb 2/5/2007 Physician Canada
Primary
Concomitant
Stress Other Serious 1/1/2007 Male 230 lb 2/5/2007 Consumer United States
Primary
Secondary
Concomitant
Muscle Twitching 51 Male 198 lb 11/21/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 11/15/2006 Female 2/13/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 3/8/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/1/2006 70 Male 4/27/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2007 78 Male 4/24/2007 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2007 81 Female 174 lb 5/2/2007 Physician United States
Primary
Concomitant
Lactic Acidosis Hospitalization 8/21/2006 61 Male 5/14/2007 Consumer Germany
Primary
Concomitant
Hypoglycaemia 11/18/2006 80 Female 2/16/2007 Physician United States
Primary
Concomitant
Vascular Calcification Hospitalization 3/23/2007 5/21/2007 Consumer United States
Primary
Secondary
Concomitant
Wheezing 1/1/2007 68 Female 2/22/2007 United States
Primary
Concomitant
Dysgeusia 4/1/2006 75 Male 2/22/2007 United States
Primary
Concomitant
Dyspnoea 1/1/2006 65 Female 2/22/2007 United States
Primary
Concomitant
Drug Ineffective 12/8/2006 84 Male 2/22/2007 United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 6/7/2007 Female 6/29/2007 Consumer United States
Primary
Concomitant
Toe Amputation Hospitalization 1/1/2007 83 Male 7/2/2007 Consumer United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 7/5/2007 77 Male 7/18/2007 Consumer Australia
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 Female 216 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/21/2007 64 Female 8/7/2007 Consumer United States
Primary
Concomitant
Skin Laceration Female 8/14/2007 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 6/7/2007 Female 8/14/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 58 Male 8/15/2007 Consumer United States
Primary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/17/2007 Pharmacist Canada
Primary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/20/2007 Pharmacist Canada
Primary
Concomitant
Hypotension Other Serious 4/5/2007 81 Female 133 lb 7/25/2007 United States
Primary
Concomitant
Drug Ineffective 4/17/2007 Female 8/31/2007 Pharmacist United States
Primary
Concomitant
Sinusitis 3/1/2007 60 Female 7/11/2007 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 6/1/2007 70 Male 8/31/2007 Germany
Primary
Concomitant
Skin Laceration Hospitalization 1/1/2006 Female 9/10/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 8/16/2007 Female 9/11/2007 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 12/1/2006 Female 9/11/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 8/16/2007 Female 9/11/2007 Consumer United States
Primary
Concomitant
Skin Laceration 9/1/2007 Female 9/12/2007 Consumer United States
Primary
Concomitant
Coronary Artery Disease Other Serious 9/12/2007 Female 287 lb 9/12/2007 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/11/2007 53 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Throat Tightness Other Serious 10/9/2007 Female 168 lb 10/30/2007 Consumer United States
Primary
Concomitant
Diabetic Neuropathy 75 Male 11/7/2007 Consumer United States
Primary
Concomitant
Dizziness 9/7/2006 76 Male 11/13/2007 Consumer United States
Primary
Concomitant
Pollakiuria 10/19/2007 52 Male 11/13/2007 Consumer United States
Primary
Concomitant
Nasal Discomfort 9/1/2007 Female 11/26/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 10/14/2007 Female 168 lb 11/28/2007 Consumer United States
Primary
Concomitant
Eye Pain 1/1/2006 Male 12/3/2007 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 7/1/2007 74 Female 11/16/2007 Physician United States
Primary
Concomitant
Pollakiuria 10/19/2007 52 Male 12/5/2007 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 7/11/2007 76 Female 118 lb 11/16/2007 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 11/16/2007 69 Female 12/17/2007 Physician Germany
Primary
Concomitant
Urinary Tract Infection 5/3/2007 71 Female 10/9/2007 Consumer United States
Primary
Concomitant
Fatigue 1/1/2004 59 Female 1/7/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/12/2007 60 Female 260 lb 10/31/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/1/2007 67 Male 1/15/2008 Physician United States
Primary
Concomitant
Paralysis Other Serious 2/1/2007 73 Male 1/28/2008 Consumer Brazil
Primary
Concomitant
Nasal Discomfort 9/1/2007 Female 1/31/2008 Consumer United States
Primary
Concomitant
Fatigue 1/1/2007 59 Female 1/31/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 200 lb 2/1/2008 Consumer United States
Primary
Concomitant
Constipation 1/25/2008 Male 2/12/2008 Consumer United States
Primary
Concomitant
Skin Laceration 1/15/2008 60 Female 2/12/2008 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 10/1/2007 62 Female 170 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Fatigue 1/1/2007 59 Female 3/3/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 70 Male 250 lb 1/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 1/10/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death 2/13/2008 69 Male 234 lb 3/7/2008 Physician
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 61 Female 170 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 7/1/2007 74 Female 2/15/2008 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 61 Female 170 lb 2/25/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/9/2008 Female 3/18/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization Female 3/18/2008 Pharmacist United States
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 10/1/2007 62 Female 170 lb 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 2/29/2008 Male 4/10/2008 Consumer United States
Primary
Concomitant
Fatigue 1/1/2007 60 Female 4/14/2008 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 52 Male 4/16/2008 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 10/1/2007 Female 4/17/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/30/2008 78 Female 86 lb 4/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 4/3/2008 Male 240 lb 4/22/2008
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 3/1/2006 Male 4/22/2008 Physician Belgium
Primary
Concomitant
Pruritus Generalised 2/15/2008 75 Female 4/25/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/9/2008 Female 143 lb 4/29/2008 Other Health Professional United States
Primary
Concomitant
Oesophagitis Hospitalization 4/9/2008 Male 240 lb 4/30/2008 United States
Primary
Concomitant
Sudden Death Death 4/13/2008 77 Female 5/1/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Laceration 1/15/2008 60 Female 5/1/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 198 lb 5/7/2008 Consumer United States
Primary
Concomitant
Dry Mouth 10/1/2007 66 Female 5/20/2008 Consumer United States
Primary
Concomitant
Collapse Of Lung Hospitalization 74 Female 5/21/2008 Consumer United States
Primary
Concomitant
Dyspnoea 1/1/2008 83 Male 5/21/2008 Consumer United States
Primary
Concomitant
Death Death 4/15/2008 Male 5/12/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 5/27/2008 Consumer Switzerland
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Female 180 lb 5/30/2008 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 5/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/28/2008 89 Male 5/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Generalised 2/15/2008 75 Female 126 lb 6/4/2008 Physician United States
Primary
Concomitant
Lacrimation Increased 5/7/2008 Female 6/6/2008 Consumer United States
Primary
Concomitant
Ulcer Life Threatening 4/30/2008 Female 6/13/2008 France
Primary
Secondary
Concomitant
Coronary Artery Bypass Other Serious 4/15/2008 77 Male 150 lb 6/16/2008 United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 4/10/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 3/1/2008 78 Female 175 lb 6/13/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 1/5/2008 61 Female 167 lb 6/10/2008 United States
Primary
Concomitant
Dyspnoea 1/1/2008 83 Male 6/24/2008 Physician United States
Primary
Concomitant
Chest Discomfort 71 Female 6/26/2008 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 3/1/2008 78 Female 180 lb 7/7/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 Female 158 lb 7/17/2008 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/1/2008 53 Female 7/21/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/8/2008 Male 265 lb 7/25/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 4/28/2008 Female 150 lb 7/28/2008 Physician Netherlands
Primary
Concomitant
Off Label Use Other Serious 3/1/2008 78 Female 180 lb 7/24/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/1/2008 53 Female 8/1/2008 Consumer United States
Primary
Concomitant
Pruritus Generalised 2/15/2008 75 Female 126 lb 8/1/2008 Physician United States
Primary
Concomitant
Lacrimation Increased 5/7/2008 Female 8/1/2008 Consumer United States
Primary
Concomitant
Urticaria Other Serious 7/28/2008 Female 160 lb 8/6/2008 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2007 Female 259 lb 8/6/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 61 Female 247 lb 8/11/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 6/22/2008 80 Female 8/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 77 Female 160 lb 7/7/2008 Consumer United States
Primary
Concomitant

Drug Data