Metformin Hcl combined with Senna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 12/7/2006 Male 12/28/2006 Pharmacist United States
Primary
Concomitant
Nephrolithiasis Other Serious 7/1/2006 52 Female 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Pain 1/1/2006 70 Female 254 lb 1/30/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 6/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Upper Limb Fracture Hospitalization 12/1/2004 94 Female 6/13/2007 United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 6/20/2007 Pharmacist United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 6/22/2007 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2007 70 Female 251 lb 8/3/2007 Physician
Primary
Secondary
Concomitant
Tremor Other Serious 70 Female 8/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2007 70 Female 8/20/2007 Physician
Primary
Secondary
Concomitant
Tremor Other Serious 5/18/2007 70 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 7/26/2007 75 Female 119 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/20/2006 Female 191 lb 8/27/2007 United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 12/10/2007 Pharmacist United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 1/24/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/5/2008 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 4/5/2008 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/5/2008 18 Male 6/23/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 4/5/2008 18 Male 6/30/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Ataxia Hospitalization 2/11/2008 Female 180 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/25/2006 70 183 lb 8/5/2008
Primary
Concomitant
Septic Embolus Other Serious 7/14/2008 Female 205 lb 8/19/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 10/13/2008 74 Female 154 lb 10/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 7/1/2006 52 Female 99 lb 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 7/1/2006 52 Female 100 lb 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Aphasia Other Serious 11/26/2008 Male 156 lb 1/14/2009 Physician United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 7/14/2008 Female 205 lb 2/2/2009 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 4/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 4/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 4/7/2009
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/31/2004 90 Female 114 lb 4/20/2009 United States
Primary
Concomitant
Sudden Death Other Serious 49 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Other Serious 49 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 4/16/2009 United States
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 11/27/2007 Female 6/17/2009 Physician United States
Primary
Secondary
Concomitant
Aphasia Other Serious 11/26/2008 Male 156 lb 7/8/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2009 Female 149 lb 7/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 Female 149 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Level Increased Death 8/27/2008 49 Female 8/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Other Serious 6/9/2009 58 Female 132 lb 8/21/2009 Physician
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 8/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/6/2009 Female 149 lb 8/27/2009 France
Primary
Secondary
Concomitant
Renal Impairment Death 8/27/2008 49 Female 8/26/2009
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 9/9/2009 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 8/19/2009 71 Female 123 lb 9/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/26/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/22/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 2/17/2009 39 Male 10/27/2009 Pharmacist
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Tuberculosis Hospitalization 5/1/2008 66 Male 139 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/16/2009 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious 9/24/2009 Female 11/27/2009 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/1/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Drug Toxicity Death 8/27/2008 49 Female 12/1/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 39 Male 11/25/2009 Physician
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/19/2009 Female 123 lb 12/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 49 Female 11/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/7/2009 Female 133 lb 12/9/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thirst Other Serious 3/13/2009 83 Male 205 lb 12/14/2009 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/15/2009 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/29/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/5/2008 18 Male 1/25/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 5/18/2007 70 Female 1/20/2010 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/29/2010 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Death 49 Female 2/17/2010 United Kingdom
Primary
Secondary
Concomitant
Drug Level Increased Death Female 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 2/6/2008 76 Male 195 lb 4/23/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 66 Male 6/15/2010 Consumer United Kingdom
Primary
Concomitant
Pericardial Effusion Hospitalization 45 Female 351 lb 8/2/2010 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization Male 8/23/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 8/27/2010 United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 8/19/2010 87 Male 10/12/2010 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 6/1/2009 18 Female 11/15/2010 Pharmacist United Kingdom
Primary
Concomitant
Dyspnoea Life Threatening 11/19/2010 62 Female 143 lb 12/16/2010 Pharmacist Canada
Primary
Concomitant
Dyspnoea Hospitalization 11/19/2010 62 Female 143 lb 1/25/2011 Physician Canada
Primary
Concomitant
Asthenia Hospitalization 2/6/2008 76 Male 195 lb 1/18/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2011 70 Female 214 lb 2/1/2011 Physician Canada
Primary
Concomitant
Large Intestinal Obstruction Death Male 2/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 12/3/2010 53 Male 250 lb 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/19/2010 62 Female 143 lb 3/16/2011 Physician Canada
Primary
Concomitant
Cellulitis Hospitalization 7/30/2010 76 Male 251 lb 3/29/2011 Physician United States
Primary
Concomitant
Meniscus Lesion Other Serious 1/1/2007 50 Male 3/29/2011 Physician United States
Primary
Concomitant
Bladder Discomfort Other Serious 1/1/2007 50 Male 4/8/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 5/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxoplasma Serology Positive Hospitalization 5/7/2005 58 Male 174 lb 6/29/2011 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 9/23/2010 51 Male 181 lb 7/6/2011 Physician United States
Primary
Concomitant
Myopathy Hospitalization 6/4/2011 83 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 2/10/2011 89 Female 7/14/2011 Consumer Switzerland
Primary
Concomitant
Vomiting Death 3/22/2011 73 Male 176 lb 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Skin Hyperpigmentation Hospitalization 3/22/2011 73 Male 176 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 3/1/2011 82 Male 8/1/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 7/27/2011 57 Female 201 lb 8/9/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 8/9/2011 Physician United Kingdom
Primary
Concomitant
Cholecystitis Acute Hospitalization 3/22/2011 73 Male 176 lb 8/8/2011 Physician United States
Primary
Concomitant
Coma Scale Abnormal Hospitalization 2/17/2009 39 Male 9/2/2011 Germany
Primary
Secondary
Concomitant
Coma Scale Abnormal Hospitalization 2/17/2009 39 Male 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 2/17/2009 39 Male 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Agitation Hospitalization 2/17/2009 39 Male 9/2/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Asthma Hospitalization 7/23/2011 55 Female 9/2/2011 Consumer Canada
Primary
Concomitant
Acute Myocardial Infarction Other Serious 3/1/2010 64 Female 9/7/2011 Physician United States
Primary
Concomitant
Overdose Other Serious 2/17/2009 39 Male 9/13/2011 Physician Germany
Primary
Secondary
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 4/21/2011 71 Female 9/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 9/11/2011 46 Female 211 lb 9/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 9/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death Female 10/3/2011 Physician United States
Primary
Concomitant
Dysphonia 55 Female 10/17/2011 Physician Canada
Primary
Concomitant
Neutropenia Life Threatening 8/17/2011 49 Female 142 lb 10/25/2011 Physician United Kingdom
Primary
Concomitant
Metastases To Peritoneum Death 66 Male 194 lb 10/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 10/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization Female 11/11/2011 Consumer United States
Primary
Concomitant

Drug Data